Libert H.K. Defize

5.1k total citations · 2 hit papers
46 papers, 4.2k citations indexed

About

Libert H.K. Defize is a scholar working on Molecular Biology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Libert H.K. Defize has authored 46 papers receiving a total of 4.2k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Molecular Biology, 16 papers in Oncology and 10 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Libert H.K. Defize's work include Protein Kinase Regulation and GTPase Signaling (9 papers), Monoclonal and Polyclonal Antibodies Research (9 papers) and Bone health and treatments (7 papers). Libert H.K. Defize is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (9 papers), Monoclonal and Polyclonal Antibodies Research (9 papers) and Bone health and treatments (7 papers). Libert H.K. Defize collaborates with scholars based in Netherlands, United States and France. Libert H.K. Defize's co-authors include Tony Hunter, Siegfried W. de Laat, James R. Woodgett, Tod Smeal, Michael Karin, William J. Boyle, Peter Angel, Marcel Karperien, Abdul‐Badi Abou‐Samra and Mark H. G. Verheijen and has published in prestigious journals such as Science, Cell and Journal of Biological Chemistry.

In The Last Decade

Libert H.K. Defize

45 papers receiving 4.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PTH/PTHrP Receptor in Early Development and Indian Hedgehog—Regulated Bone Growth

1996 1.0k citations Beate Lanske, Marcel Karperien et al. profile →
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 949 citations Libert H.K. Defize, Tony Hunter et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Libert H.K. Defize Netherlands	28	3.2k	1.2k	620	412	368	46	4.2k
Robert A. Nissenson United States	38	3.3k 1.0×	2.0k 1.8×	535 0.9×	227 0.6×	170 0.5×	112	5.0k
T.B. Shows United States	37	2.3k 0.7×	766 0.7×	798 1.3×	586 1.4×	374 1.0×	77	4.4k
Joan Levy United States	28	2.6k 0.8×	955 0.8×	250 0.4×	545 1.3×	406 1.1×	58	3.6k
Guy Boileau Canada	35	1.7k 0.5×	1.1k 0.9×	384 0.6×	428 1.0×	275 0.7×	128	3.6k
Stephen A. Kaufman United States	24	3.3k 1.0×	1.2k 1.1×	279 0.5×	344 0.8×	589 1.6×	64	5.4k
Paul Stroobant United Kingdom	23	2.5k 0.8×	758 0.7×	599 1.0×	396 1.0×	435 1.2×	28	4.4k
Senén Vilaró Spain	39	2.0k 0.6×	739 0.6×	368 0.6×	795 1.9×	438 1.2×	108	4.3k
Anthony J. Mason United States	35	4.8k 1.5×	664 0.6×	1.2k 2.0×	348 0.8×	262 0.7×	53	7.6k
Robert Kypta United Kingdom	32	4.0k 1.3×	991 0.9×	611 1.0×	604 1.5×	656 1.8×	59	5.3k
Angie Rizzino United States	43	4.3k 1.3×	896 0.8×	740 1.2×	298 0.7×	751 2.0×	140	5.7k

Countries citing papers authored by Libert H.K. Defize

Since Specialization

Citations

This map shows the geographic impact of Libert H.K. Defize's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Libert H.K. Defize with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Libert H.K. Defize more than expected).

Fields of papers citing papers by Libert H.K. Defize

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Libert H.K. Defize. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Libert H.K. Defize. The network helps show where Libert H.K. Defize may publish in the future.

Co-authorship network of co-authors of Libert H.K. Defize

This figure shows the co-authorship network connecting the top 25 collaborators of Libert H.K. Defize. A scholar is included among the top collaborators of Libert H.K. Defize based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Libert H.K. Defize. Libert H.K. Defize is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Moolenaar, Wouter H., Libert H.K. Defize, & Siegfried W. de Laat. (2007). Calcium in the Action of Growth Factors. Novartis Foundation symposium. 122. 212–231.

Heyden, Marcel A. G. van der & Libert H.K. Defize. (2003). Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us about cardiomyocyte differentiation. Cardiovascular Research. 58(2). 292–302. 151 indexed citations

Heyden, Marcel A. G. van der, Jacqueline M. Veltmaat, Jeanine Hendriks, Olivier Destrée, & Libert H.K. Defize. (2000). Dynamic connexin43 expression and gap junctional communication during endoderm differentiation of F9 embryonal carcinoma cells. European Journal of Cell Biology. 79(4). 272–282. 8 indexed citations

Veltmaat, Jacqueline M., et al.. (2000). Cloning and analysis of the mouse follistatin promoter. Molecular Biology Reports. 27(3). 129–139. 19 indexed citations

Verheijen, Mark H. G., Marcel Karperien, Ung‐il Chung, et al.. (1999). Parathyroid hormone-related peptide (PTHrP) induces parietal endoderm formation exclusively via the Type I PTH/PTHrP receptor. Mechanisms of Development. 81(1-2). 151–161. 22 indexed citations

Verheijen, Mark H. G., Rob M.F. Wolthuis, Johannes L. Bos, & Libert H.K. Defize. (1999). The Ras/Erk Pathway Induces Primitive Endoderm but Prevents Parietal Endoderm Differentiation of F9 Embryonal Carcinoma Cells. Journal of Biological Chemistry. 274(3). 1487–1494. 49 indexed citations

Laat, Siegfried W. de, Johannes Boonstra, Libert H.K. Defize, et al.. (1999). Growth factor signalling. The International Journal of Developmental Biology. 43(7). 681–691. 10 indexed citations

Karperien, Marcel, Hetty Farih-Sips, Jeanine Hendriks, et al.. (1999). Identification of a Retinoic Acid-Inducible Element in the Murine PTH/PTHrP (Parathyroid Hormone/Parathyroid Hormone-Related Peptide) Receptor Gene. Molecular Endocrinology. 13(7). 1183–1196. 16 indexed citations

Verheijen, Mark H. G., Rob M.F. Wolthuis, Libert H.K. Defize, Jeroen den Hertog, & Johannes L. Bos. (1999). Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells. Oncogene. 18(31). 4435–4439. 27 indexed citations

10.

Verheijen, Mark H. G. & Libert H.K. Defize. (1997). Parathyroid Hormone Activates Mitogen-activated Protein Kinase via a cAMP-mediated Pathway Independent of Ras. Journal of Biological Chemistry. 272(6). 3423–3429. 78 indexed citations

11.

Karperien, Marcel, Peter H. Lanser, Siegfried W. de Laat, J. Boonstra, & Libert H.K. Defize. (1996). Parathyroid hormone related peptide mRNA expression during murine postimplantation development: evidence for involvement in multiple differentiation processes. The International Journal of Developmental Biology. 40(3). 599–608. 46 indexed citations

12.

Karperien, Marcel, Thamar B. van Dijk, Fons Cremers, et al.. (1994). Expression pattern of parathyroid hormone/parathyroid hormone related peptide receptor mRNA in mouse postimplantation embryos indicates involvement in multiple developmental processes. Mechanisms of Development. 47(1). 29–42. 62 indexed citations

13.

Stolpe, Anja van de, Marcel Karperien, Clemens W.G.M. Löwik, et al.. (1993). Parathyroid hormone-related peptide as an endogenous inducer of parietal endoderm differentiation.. The Journal of Cell Biology. 120(1). 235–243. 92 indexed citations

14.

Spaargaren, Marcel, Libert H.K. Defize, J. Boonstra, & Siegfried W. de Laat. (1991). Antibody-induced dimerization activates the epidermal growth factor receptor tyrosine kinase. Journal of Biological Chemistry. 266(3). 1733–1739. 83 indexed citations

15.

Kruyt, Frank A.E., C.E. van den Brink, Libert H.K. Defize, et al.. (1991). Transcriptional regulation of retinoic acid receptor β in retinoic acid-sensitive and -resistant P19 embryocarcinoma cells. Mechanisms of Development. 33(3). 171–178. 48 indexed citations

16.

Defize, Libert H.K., J. Boonstra, Jill Meisenhelder, et al.. (1989). Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors.. The Journal of Cell Biology. 109(5). 2495–2507. 169 indexed citations

17.

Brahma, S. K., David S. McDevitt, & Libert H.K. Defize. (1987). Ontogeny of αA and αB crystallin polypeptides during Rana temporaria lens development. Experimental Eye Research. 45(2). 253–261. 7 indexed citations

18.

Defize, Libert H.K. & Siegfried W. de Laat. (1986). Chapter 15 Structural and functional aspects of epidermal growth factor (EGF) and its receptor. Progress in brain research. 69. 169–182. 4 indexed citations

19.

Defize, Libert H.K., Wouter H. Moolenaar, Paul T. van der Saag, & Siegfried W. de Laat. (1986). Dissociation of cellular responses to epidermal growth factor using anti-receptor monoclonal antibodies.. The EMBO Journal. 5(6). 1187–1192. 56 indexed citations

20.

Wiegant, F. A. C., et al.. (1986). Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells.. The Journal of Cell Biology. 103(1). 87–94. 121 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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