Tom Maniatis

231.7k citations

278 papers · 190.2k indexed · 46 hit papers · h-index 137

Impact in

Molecular Biology top 0.01%
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
- CRISPR and Genetic Engineering
Genetics top 0.01%
- Bacterial Genetics and Biotechnology

Papers in

Genetics 38
- Hemoglobinopathies and Related Disorders 22
Molecular Biology 212
- RNA Research and Splicing 80
- RNA and protein synthesis mechanisms 67
- RNA modifications and cancer 37
- DNA and Nucleic Acid Chemistry 28
- Genomics and Chromatin Dynamics 25

Co-authors: Joseph Sambrook Dimitris Thanos Kai Zinn Robin Reed Douglas A. Melton Andrea Jeffrey Michael R. Rebagliati Paul A. Krieg
Journals: Cell (58 papers)Proceedings of the National Academy of Sciences (41 papers)Molecular and Cellular Biology (24 papers)Nature (21 papers)Science (15 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Tom Maniatis

277 papers receiving 182.7k citations

Hit Papers

15 papers align trajectories log scale

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function 2015 · 648 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 Cell
2014 Neuron
2014 Journal of Neuroscience
2013 Cell Reports
2013 Nature Methods
2012 Nature
2007 Molecular Cell
2007 Nature Neuroscience
2003 Nature Immunology
2002 Nature
2002 Nature
2000 Cell
1999 Cell
1998 Molecular Cell
1996 Cell
1995 Cell
1995 Proceedings of the National Academy of Sciences
1995 The FASEB Journal
1995 Genes & Development
1995 Cell
1994 Cell
1993 Cell
1992 Cell
1990 Nature
1989 Medical Entomology and Zoology
1989 Medical Entomology and Zoology
1987 Nature
1987 Methods in enzymology on CD-ROM/Methods in enzymology
1987 Science
1986 Science
1985 Nucleic Acids Research
1984 Nucleic Acids Research
1984 Cell
1984 Cell
1984 Cell
1983 Nature
1983 Cell
1981 Cell
1980 Cell
1980 The Structure and Evolution of the Human /?-Globin Gene Family
1979 Cell
1978 Cell
1978 Cell
1976 Cell
1975 Biochemistry
1975 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Tom Maniatis

Since Specialization

Citations

This map shows the geographic impact of Tom Maniatis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom Maniatis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom Maniatis more than expected).

Fields of papers citing papers by Tom Maniatis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom Maniatis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom Maniatis. The network helps show where Tom Maniatis may publish in the future.

Co-authors

The 25 scholars most cited alongside Tom Maniatis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tom Maniatis Line = papers co-authored together Tom Maniatis links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Genotype-specific interferon signatures in amyotrophic lateral sclerosis relate to disease severity Brain ·Olga Carletta, Camilla Perfetto, Olivia M. Rifai, Francesca Manganelli, Fergal M. Waldron, Tom Maniatis, Jenna M. Gregory, Valeria Gerbino	2025	1
2	ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy Proceedings of the National Academy of Sciences ·Olivia Harding, Chantell S. Evans, Junqiang Ye, Jonah Cheung, Tom Maniatis, Erika L.F. Holzbaur	2021	68
3	Effects of ALS-associated TANK binding kinase 1 mutations on protein–protein interactions and kinase activity Proceedings of the National Academy of Sciences ·Junqiang Ye, Jonah Cheung, Valeria Gerbino, Göran Ahlsén, Christina M. Zimanyi, David Hirsh, Tom Maniatis	2019	32
4	Distinct roles for motor neuron autophagy early and late in the SOD1 ^G93A mouse model of ALS Proceedings of the National Academy of Sciences ·Noam D. Rudnick, Christopher J. Griffey, Paolo Guarnieri, Valeria Gerbino, Xueyong Wang, Jason Piersaint, Juan Carlos Tapia, Mark M. Rich, Tom Maniatis	2017	151
5	Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly Science ·George Mountoufaris, Weisheng V. Chen, Yusuke Hirabayashi, Sean O’Keeffe, Maxime Chevée, Chiamaka L. Nwakeze, Franck Polleux, Tom Maniatis	2017	105
6	Prevalent presence of periodic actin–spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species Proceedings of the National Academy of Sciences ·Jiang He, Ruobo Zhou, Zhuhao Wu, Mónica A. Carrasco, Peri T. Kurshan, Jonathan E. Farley, David Simon, Guiping Wang, Boran Han, Junjie Hao, Evan Heller, Marc Freeman, Kang Shen, Tom Maniatis, Marc Tessier‐Lavigne, Xiaowei Zhuang	2016	121
7	Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions Cell ·Rotem Rubinstein, Chan Aye Thu, K.M. Goodman, Holly N. Wolcott, Fabiana Bahna, Seetha Mannepalli, Göran Ahlsén, Maxime Chevée, Adnan Halim, Henrik Clausen, Tom Maniatis, Lawrence Shapiro, Barry Honig	2015	122
8	Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells Journal of Neuroscience ·Mackenzie W. Amoroso, Gist F. Croft, Damian J. Williams, Sean O’Keeffe, Mónica A. Carrasco, Anne Davis, Laurent Roybon, Derek H. Oakley, Tom Maniatis, Christopher E. Henderson, Hynek Wichterle	2013	191
9	Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability Proceedings of the National Academy of Sciences ·Bilada Bilican, Andrea Serio, Sami J. Barmada, Agnes L. Nishimura, Gareth J. Sullivan, Mónica A. Carrasco, Hemali Phatnani, Clare A. Puddifoot, David Story, Judy Fletcher, In-Hyun Park, Brad A. Friedman, George Q. Daley, David J. A. Wyllie, Giles E. Hardingham, Ian Wilmut, Steven Finkbeiner, Tom Maniatis, Christopher E. Shaw, Siddharthan Chandran	2012	257
10	A dimer-specific function of the transcription factor NFATp Proceedings of the National Academy of Sciences ·James V. Falvo, Charles Lin, Alla V. Tsytsykova, Peter K. Hwang, Dimitris Thanos, Anne E. Goldfeld, Tom Maniatis	2008	19
11	IFN-regulatory factor 3-dependent gene expression is defective in Tbk1 -deficient mouse embryonic fibroblasts Proceedings of the National Academy of Sciences ·Sarah M. McWhirter, Katherine A. Fitzgerald, Jacqueline Rosains, Daniel C. Rowe, Douglas T. Golenbock, Tom Maniatis	2003	454
12	Caspase-mediated processing of the Drosophila NF-κB factor Relish Proceedings of the National Academy of Sciences ·Svenja Stöven, Neal Silverman, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk, Ylva Engström, Tom Maniatis, Dan Hultmark	2003	276
13	IKKε and TBK1 are essential components of the IRF3 signaling pathway Nature Immunology ·Katherine A. Fitzgerald, Sarah M. McWhirter, L. Kerrie, Daniel C. Rowe, Eicke Latz, Douglas T. Golenbock, Anthony J. Coyle, Sha-Mei Liao, Tom Maniatis Hit paper breakdown →	2003	2204
14	PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins Genes & Development ·Bing Ren, Kerlen J. Chee, Tae Hoon Kim, Tom Maniatis	1999	225
15	Multiple Distinct Splicing Enhancers in the Protein-Coding Sequences of a Constitutively Spliced Pre-mRNA Molecular and Cellular Biology ·Thomas Schaal, Tom Maniatis	1999	163
16	Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter Molecular Cell ·Bhavin S. Parekh, Tom Maniatis	1999	221
17	In vitro assembly of enhancer complexes Methods in enzymology on CD-ROM/Methods in enzymology ·Dimitris Thanos, Tom Maniatis	1996	11
18	Identification of the rel Family Members Required for Virus Induction of the Human Beta Interferon Gene Molecular and Cellular Biology ·Dimitris Thanos, Tom Maniatis	1995	124
19	44 Positive and Negative Control of Human Interferon-β Gene Expression Cold Spring Harbor Monograph Archive ·Tom Maniatis, Lisa-Anne Whittemore, Wei Du, Chen‐Ming Fan, Andrew Keller, Vito J. Palombella, Dimitrios N. Thanos	1992	6
20	Inducible Processing of Interferon Regulatory Factor-2 Molecular and Cellular Biology ·Vito J. Palombella, Tom Maniatis	1992	13

About Tom Maniatis

Tom Maniatis is a scholar working on Genetics, Molecular Biology, Immunology, Cancer Research and Cellular and Molecular Neuroscience, having authored 278 papers that have together received 190.2k indexed citations. Recurring topics across this work include RNA Research and Splicing (80 papers), RNA and protein synthesis mechanisms (67 papers), interferon and immune responses (45 papers), RNA modifications and cancer (37 papers), DNA and Nucleic Acid Chemistry (28 papers), NF-κB Signaling Pathways (27 papers), Genomics and Chromatin Dynamics (25 papers) and Hemoglobinopathies and Related Disorders (22 papers). The work is most often cited by research in Molecular Biology (121.0k citations), Genetics (35.1k citations), Immunology (24.2k citations), Endocrinology (5.4k citations) and Biotechnology (7.9k citations). Tom Maniatis has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Joseph Sambrook, Dimitris Thanos, Kai Zinn, Robin Reed, Douglas A. Melton, Andrea Jeffrey, Michael R. Rebagliati, Paul A. Krieg, R Myers and Stephen Goodbourn. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences, Molecular and Cellular Biology, Nature and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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