Thomas D. Schmittgen

221.1k total citations · 9 hit papers
95 papers, 181.3k citations indexed

About

Thomas D. Schmittgen is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Thomas D. Schmittgen has authored 95 papers receiving a total of 181.3k indexed citations (citations by other indexed papers that have themselves been cited), including 76 papers in Molecular Biology, 55 papers in Cancer Research and 14 papers in Oncology. Recurrent topics in Thomas D. Schmittgen's work include MicroRNA in disease regulation (51 papers), Cancer-related molecular mechanisms research (25 papers) and RNA modifications and cancer (21 papers). Thomas D. Schmittgen is often cited by papers focused on MicroRNA in disease regulation (51 papers), Cancer-related molecular mechanisms research (25 papers) and RNA modifications and cancer (21 papers). Thomas D. Schmittgen collaborates with scholars based in United States, United Kingdom and India. Thomas D. Schmittgen's co-authors include Kenneth J. Livak, Brian A. Zakrajsek, Jinmai Jiang, Eun Joo Lee, Yuriy Gusev, Daniel J. Brackett, Gerard J. Nuovo, Jong Kook Park, Tushar Patel and Michael W. Reed and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and SHILAP Revista de lepidopterología.

In The Last Decade

Thomas D. Schmittgen

93 papers receiving 179.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 149.2k citations Kenneth J. Livak, Thomas D. Schmittgen Methods profile →
Analyzing real-time PCR data by the comparative CT method

2008 21.1k citations Thomas D. Schmittgen, Kenneth J. Livak Nature Protocols profile →
Detection of microRNA Expression in Human Peripheral Blood Microvesicles

2008 1.2k citations Thomas D. Schmittgen, S. Patrick Nana‐Sinkam et al. PLoS ONE profile →
Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR

2000 1.1k citations Thomas D. Schmittgen et al. profile →
Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods

2000 883 citations Thomas D. Schmittgen et al. profile →
Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

2006 826 citations Jinmai Jiang, Thomas D. Schmittgen et al. profile →
Expression profiling identifies microRNA signature in pancreatic cancer

2006 740 citations Eun Joo Lee, Yuriy Gusev et al. International Journal of Cancer profile →
MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

2009 515 citations Jinmai Jiang, Thomas D. Schmittgen et al. Cancer Research profile →
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

2017 447 citations Jinmai Jiang, Thomas D. Schmittgen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas D. Schmittgen United States	40	89.2k	37.3k	28.2k	23.7k	14.1k	95	181.3k
Kenneth J. Livak United States	42	95.0k 1.1×	44.4k 1.2×	23.5k 0.8×	26.2k 1.1×	19.0k 1.3×	95	199.5k
Wolfgang Huber Germany	72	67.0k 0.8×	17.8k 0.5×	14.6k 0.5×	12.8k 0.5×	12.6k 0.9×	249	109.8k
Tom Maniatis United States	137	121.0k 1.4×	27.6k 0.7×	12.3k 0.4×	24.2k 1.0×	35.1k 2.5×	278	190.2k
Mark A. Bradford United States	72	109.9k 1.2×	57.1k 1.5×	5.8k 0.2×	12.8k 0.5×	14.9k 1.1×	229	239.7k
Ulrich K. Laemmli Switzerland	62	154.2k 1.7×	33.5k 0.9×	10.0k 0.4×	24.1k 1.0×	29.5k 2.1×	84	261.7k
Simon Anders Germany	31	51.5k 0.6×	15.8k 0.4×	11.8k 0.4×	10.7k 0.4×	9.6k 0.7×	59	87.9k
Masayuki Yamamoto Japan	169	85.7k 1.0×	7.2k 0.2×	9.1k 0.3×	11.1k 0.5×	5.4k 0.4×	1.4k	119.9k
Cole Trapnell United States	60	58.9k 0.7×	16.3k 0.4×	16.6k 0.6×	9.6k 0.4×	9.4k 0.7×	102	85.0k
Joseph Sambrook United States	49	78.4k 0.9×	24.3k 0.7×	4.1k 0.1×	9.6k 0.4×	25.9k 1.8×	339	127.1k
A. Farr United States	7	143.2k 1.6×	33.7k 0.9×	12.4k 0.4×	14.4k 0.6×	18.5k 1.3×	7	295.7k

Countries citing papers authored by Thomas D. Schmittgen

Since Specialization

Citations

This map shows the geographic impact of Thomas D. Schmittgen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas D. Schmittgen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas D. Schmittgen more than expected).

Fields of papers citing papers by Thomas D. Schmittgen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas D. Schmittgen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas D. Schmittgen. The network helps show where Thomas D. Schmittgen may publish in the future.

Co-authorship network of co-authors of Thomas D. Schmittgen

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas D. Schmittgen. A scholar is included among the top collaborators of Thomas D. Schmittgen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas D. Schmittgen. Thomas D. Schmittgen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Treekitkarnmongkol, Warapen, Mei-Chee Tai, Sanchita Rauth, et al.. (2025). RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer. Nature Cell Biology. 28(1). 197–206.

Greenberg, Zachary, Andrew Brock, Jinmai Jiang, et al.. (2025). Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy. Journal of Nanobiotechnology. 23(1). 467–467. 1 indexed citations

Duraivel, Senthilkumar, Jinmai Jiang, Jonathan Fischer, et al.. (2025). RNA Sequencing at Single Vesicle Resolution via 3D Printed Embedded Droplet Arrays. ACS Applied Materials & Interfaces. 17(38). 53110–53121. 1 indexed citations

Vozmediano, Valvanera, Rodrigo Cristofoletti, Jinmai Jiang, et al.. (2024). Rerouting cardiovascular management following gastric bypass surgery: Dose optimization of carvedilol using population‐based analysis. British Journal of Clinical Pharmacology. 90(9). 2223–2235. 1 indexed citations

Atanasova, Kalina R., Ranjala Ratnayake, Jinmai Jiang, et al.. (2024). Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids. Frontiers in Pharmacology. 15. 1335246–1335246. 4 indexed citations

Wilkerson, Jenny L., et al.. (2020). Alterations in mouse spinal cord and sciatic nerve microRNAs after the chronic constriction injury (CCI) model of neuropathic pain. Neuroscience Letters. 731. 135029–135029. 18 indexed citations

Park, Jong Kook, Takayuki Kogure, Gerard J. Nuovo, et al.. (2011). miR-221 Silencing Blocks Hepatocellular Carcinoma and Promotes Survival. Cancer Research. 71(24). 7608–7616. 180 indexed citations

Henry, Jon C., Ana Clara P. Azevedo‐Pouly, & Thomas D. Schmittgen. (2011). microRNA Replacement Therapy for Cancer. Pharmaceutical Research. 28(12). 3030–3042. 121 indexed citations

Park, Jong Kook, Jon C. Henry, Jinmai Jiang, et al.. (2011). miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor. Biochemical and Biophysical Research Communications. 406(4). 518–523. 147 indexed citations

10.

Narayanan, Ramesh, Jinmai Jiang, Yuriy Gusev, et al.. (2010). MicroRNAs Are Mediators of Androgen Action in Prostate and Muscle. PLoS ONE. 5(10). e13637–e13637. 49 indexed citations

11.

Henry, Jon C., Jong Kook Park, Jinmai Jiang, et al.. (2010). miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines. Biochemical and Biophysical Research Communications. 403(1). 120–125. 118 indexed citations

12.

Hackanson, Björn, Kristi L. Bennett, Romulo Martin Brena, et al.. (2008). Epigenetic Modification of CCAAT/Enhancer Binding Protein α Expression in Acute Myeloid Leukemia. Cancer Research. 68(9). 3142–3151. 114 indexed citations

13.

Jiang, Jinmai, Yuriy Gusev, Ileana Aderca, et al.. (2008). Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival. Clinical Cancer Research. 14(2). 419–427. 422 indexed citations

14.

Blower, Paul E., Ji-Hyun Chung, Joseph S. Verducci, et al.. (2008). MicroRNAs modulate the chemosensitivity of tumor cells. Molecular Cancer Therapeutics. 7(1). 1–9. 294 indexed citations

15.

Schmittgen, Thomas D. & Kenneth J. Livak. (2008). Analyzing real-time PCR data by the comparative CT method. Nature Protocols. 3(6). 1101–1108. 21053 indexed citations breakdown →

16.

Nana‐Sinkam, S. Patrick, Melissa Hunter, Gerard J. Nuovo, et al.. (2008). Integrating the MicroRNome into the Study of Lung Disease. American Journal of Respiratory and Critical Care Medicine. 179(1). 4–10. 79 indexed citations

17.

Gusev, Yuriy, Thomas D. Schmittgen, Megan R. Lerner, Russell G. Postier, & Daniel J. Brackett. (2007). Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer. BMC Bioinformatics. 8(S7). S16–S16. 60 indexed citations

18.

Foraker, Amy B., et al.. (2007). Dynamin 2 Regulates Riboflavin Endocytosis in Human Placental Trophoblasts. Molecular Pharmacology. 72(3). 553–562. 16 indexed citations

19.

Lee, Eun Joo, Yuriy Gusev, Jinmai Jiang, et al.. (2006). Expression profiling identifies microRNA signature in pancreatic cancer. International Journal of Cancer. 120(5). 1046–1054. 740 indexed citations breakdown →

20.

Livak, Kenneth J. & Thomas D. Schmittgen. (2001). Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method. Methods. 25(4). 402–408. 149151 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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