Lawrence Shapiro

33.9k citations

189 papers · 16.1k indexed · 7 hit papers · h-index 69

Impact in

Virology top 0.5%
- HIV Research and Treatment
Cell Biology top 0.1%
- Cellular Mechanics and Interactions

Papers in

Cell Biology 54
- Cellular Mechanics and Interactions 25
- Skin and Cellular Biology Research 15
Virology 15
- HIV Research and Treatment 14

Co-authors: Barry Honig David Colman Philipp E. Scherer Peter D. Kwong Dinshaw J. Patel Julia Brasch Wayne A. Hendrickson Fabiana Bahna
Journals: Proceedings of the National Academy of Sciences (18 papers)Neuron (13 papers)Cell Reports (12 papers)Structure (12 papers)Nature Communications (9 papers)
Partner nations: United States Russia United Kingdom

In The Last Decade

Lawrence Shapiro

187 papers receiving 15.8k citations

Hit Papers

7 papers align trajectories log scale

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization 2021 · 390 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Cell Host & Microbe
2011 Structure
2010 Science
2004 Journal of Biological Chemistry
2002 Science
1998 Current Biology
1995 Nature

Peers

Countries citing papers authored by Lawrence Shapiro

Since Specialization

Citations

This map shows the geographic impact of Lawrence Shapiro's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence Shapiro with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence Shapiro more than expected).

Fields of papers citing papers by Lawrence Shapiro

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence Shapiro. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence Shapiro. The network helps show where Lawrence Shapiro may publish in the future.

Co-authors

The 25 scholars most cited alongside Lawrence Shapiro, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lawrence Shapiro Line = papers co-authored together Lawrence Shapiro links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2 Nature Communications ·Qian Wang, Yicheng Guo, Ryan G. Casner, Jian Yu, Manoj S. Nair, Jerren Ho, Eswar R. Reddem, Ian A. Mellis, Madeline Wu, Anwar Mukammi Kulaib Alruwaili, Shilu Tong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D. Ho	2025	2
2	Push-pull mechanics of E-cadherin ectodomains in biomimetic adhesions Biophysical Journal ·Y. Outa, I. V. Sutyagin, Julio César Saldaña Pumarica, Gilbert McGaughren, Gaetano Pero, O.J. Harrison, Léa-Lætitia Pontani, Lawrence Shapiro, Barry Honig, Jasna Brujić	2023	3
3	Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus PLoS Pathogens ·Li Ou, WU Zi-gui., I‐Ting Teng, Lijuan Yang, Baoshan Zhang, Tongqing Zhou, Tiffany Carro, Cheng Cheng, Wing‐Pui Kong, Nicholas C. Morano, 向後保雄, John-Paul Todd, Yaroslav Tsybovsky, Shuishu Wang, H. Kahles, John R. Mascola, Lawrence Shapiro, Ruth Woodward, Ursula J. Buchholz, Peter D. Kwong	2023	5
4	Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site Structure ·Tongqing Zhou, Lei Chen, Jason Gorman, Shuishu Wang, Young Do Kwon, Bob C. Lin, Mark K. Louder, Reda Rawi, 向後保雄, Yongping Yang, Baoshan Zhang, Kimberly A. Bettes, Laura E. McCoy, Lucy Rutten, Theo Verrips, Robin A. Weiss, Nicole A. Doria-Rose, Lawrence Shapiro, Peter D. Kwong	2022	9
5	Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules Cell Reports ·Shuwa Xu, Alina P. Sergeeva, Phinikoula S. Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, S Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn	2022	10
6	Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain Cell Reports ·Gabriele Cerutti, Yicheng Guo, Pengfei Wang, Manoj S. Nair, Maple Wang, Yaoxing Huang, Jian Yu, Lihong Liu, Phinikoula S. Katsamba, Fabiana Bahna, Eswar R. Reddem, Peter D. Kwong, David D. Ho, Zizhang Sheng, Lawrence Shapiro	2021	42
7	Elasticity of individual protocadherin 15 molecules implicates tip links as the gating springs for hearing Proceedings of the National Academy of Sciences ·Hong Weitao, Felicitas E. Hengel, Toyoko Orimoto, Gäumann, 成章荻林, 恭次木本, C. Sanna, Lawrence Shapiro, Ulrich Müller, A. J. Hudspeth	2019	44
8	Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins Proceedings of the National Academy of Sciences ·Ida Signe Bohse Larsen, Yoshiki Narimatsu, Hiren J. Joshi, El Salmy Salah El Din, O.J. Harrison, Julia Brasch, K.M. Goodman, Lars Hestbjerg Hansen, Lawrence Shapiro, Barry Honig, Sergey Y. Vakhrushev, Henrik Clausen, Adnan Halim	2017	78
9	Structural basis of adhesive binding by desmocollins and desmogleins Proceedings of the National Academy of Sciences ·O.J. Harrison, Julia Brasch, Gorka Lasso, Phinikoula S. Katsamba, Göran Ahlsén, Barry Honig, Lawrence Shapiro	2016	130
10	Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation Science ·Vasileios I. Petrou, Carmen M. Herrera, Kathryn M. Schultz, Oliver B. Clarke, Jérémie Vendôme, David Tomasek, Surajit Banerjee, Kanagalaghatta R. Rajashankar, Meagan Belcher Dufrisne, Brian Kloss, Edda Kloppmann, Burkhard Rost, Candice S. Klug, M. Stephen Trent, Lawrence Shapiro, Filippo Mancia	2016	96
11	Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection PLoS Computational Biology ·Zizhang Sheng, Chaim A. Schramm, Mark Connors, Lynn Morris, John R. Mascola, Peter D. Kwong, Lawrence Shapiro	2016	23
12	FGF5 is a crucial regulator of hair length in humans Proceedings of the National Academy of Sciences ·Claire A. Higgins, Lynn Petukhova, Sivan Harel, E. N., Esther Drill, Lawrence Shapiro, Muhammad Wajid, Angela M. Christiano	2014	126
13	Structures from Anomalous Diffraction of Native Biological Macromolecules Science ·Qun Liu, Tassadite Dahmane, Zhen Zhang, Zahra Assur, Julia Brasch, Lawrence Shapiro, Filippo Mancia, Wayne A. Hendrickson	2012	129
14	Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Proceedings of the National Academy of Sciences ·Young Do Kwon, Andrés Finzi, Xueling Wu, Cajetan Dogo‐Isonagie, Lawrence K. Lee, Lucas R. Moore, Stephen D. Schmidt, Jonathan Stuckey, Yongping Yang, Tongqing Zhou, Jiang Zhu, David A. Vicic, Asim K. Debnath, Lawrence Shapiro, Carole A. Bewley, John R. Mascola, Joseph Sodroski, Peter D. Kwong	2012	197
15	Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 Science ·Tongqing Zhou, Ivelin S. Georgiev, Xueling Wu, Zhi-Yong Yang, Kaifan Dai, Andrés Finzi, Young Do Kwon, Johannes F. Scheid, Wei Shi, Ling Xu, Yongping Yang, Jiang Zhu, Michel C. Nussenzweig, Joseph Sodroski, Lawrence Shapiro, Gary J. Nabel, John R. Mascola, Peter D. Kwong Hit paper breakdown →	2010	821
16	Adiponectin Deficiency Limits Tumor Vascularization in the MMTV-PyV-mT Mouse Model of Mammary Cancer Clinical Cancer Research ·Martin S. Denzel, Lionel Hebbard, Nicolas Luc Bize, Lawrence Shapiro, Robert D. Cardiff, Barbara Ranscht	2009	75
17	Crystal Structures of the Adenylate Sensor from Fission Yeast AMP-Activated Protein Kinase Science ·Robert Townley, Lawrence Shapiro	2007	148
18	Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide Protein Science ·Jason Gorman, Lawrence Shapiro	2005	22
19	G-Protein Signaling Through Tubby Proteins Science ·Sandro Santagata, Titus J. Boggon, Cheryl L. Baird, Carlos A. Gómez, 礼二田中, Ahed Nahhas, David G. Myszka, Lawrence Shapiro	2001	302
20	Isolation of intact CNS synaptic junctions The maintenance of synaptic adhesion The Society for Neuroscience Abstracts ·Greg R. Phillips, 康代岬, Sarath Gamini de Silva, Kirsten Arndt, Lawrence Shapiro, David Colman	1999	1

About Lawrence Shapiro

Lawrence Shapiro is a scholar working on Cell Biology, Virology, Structural Biology, Cellular and Molecular Neuroscience and Molecular Biology, having authored 189 papers that have together received 16.1k indexed citations. Recurring topics across this work include Wnt/β-catenin signaling in development and cancer (50 papers), Cellular Mechanics and Interactions (25 papers), Monoclonal and Polyclonal Antibodies Research (22 papers), Protein Structure and Dynamics (19 papers), RNA and protein synthesis mechanisms (18 papers), Axon Guidance and Neuronal Signaling (18 papers), Skin and Cellular Biology Research (15 papers) and HIV Research and Treatment (14 papers). The work is most often cited by research in Virology (1.2k citations), Cell Biology (3.9k citations), Molecular Biology (9.8k citations), Biochemistry (909 citations) and Cellular and Molecular Neuroscience (2.3k citations). Lawrence Shapiro has collaborated with scholars based in United States, Russia and United Kingdom. Frequent co-authors include Barry Honig, David Colman, Philipp E. Scherer, Peter D. Kwong, Dinshaw J. Patel, Julia Brasch, Wayne A. Hendrickson, Fabiana Bahna, Göran Ahlsén and O.J. Harrison. Their work appears in journals such as Proceedings of the National Academy of Sciences, Neuron, Cell Reports, Structure and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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