Thomas A. Baillie

15.9k total citations · 5 hit papers
210 papers, 12.1k citations indexed

About

Thomas A. Baillie is a scholar working on Pharmacology, Molecular Biology and Spectroscopy. According to data from OpenAlex, Thomas A. Baillie has authored 210 papers receiving a total of 12.1k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Pharmacology, 70 papers in Molecular Biology and 43 papers in Spectroscopy. Recurrent topics in Thomas A. Baillie's work include Pharmacogenetics and Drug Metabolism (90 papers), Analytical Chemistry and Chromatography (36 papers) and Drug Transport and Resistance Mechanisms (34 papers). Thomas A. Baillie is often cited by papers focused on Pharmacogenetics and Drug Metabolism (90 papers), Analytical Chemistry and Chromatography (36 papers) and Drug Transport and Resistance Mechanisms (34 papers). Thomas A. Baillie collaborates with scholars based in United States, United Kingdom and Japan. Thomas A. Baillie's co-authors include Juswinder Singh, Adrian Whitty, Russell C. Petter, Margaret R. Davis, Jiunn H. Lin, David C. Evans, Paul G. Pearson, Deborah A. Nicoll‐Griffith, Allan E. Rettie and Albert W. Rettenmeier and has published in prestigious journals such as Science, Journal of Biological Chemistry and Angewandte Chemie International Edition.

In The Last Decade

Thomas A. Baillie

208 papers receiving 11.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The resurgence of covalent drugs

2011 1.4k citations Thomas A. Baillie et al. Nature Reviews Drug Discovery profile →
Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development

2003 511 citations David C. Evans, Deborah A. Nicoll‐Griffith et al. Chemical Research in Toxicology profile →
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States

2011 494 citations Thomas A. Baillie et al. Chemical Research in Toxicology profile →
Targeted Covalent Inhibitors for Drug Design

2016 423 citations Thomas A. Baillie profile →
Managing the challenge of chemically reactive metabolites in drug development

2011 338 citations B. Kevin Park, Alan R. Boobis et al. Nature Reviews Drug Discovery profile →

Peers

Countries citing papers authored by Thomas A. Baillie

Since Specialization

Citations

This map shows the geographic impact of Thomas A. Baillie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas A. Baillie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas A. Baillie more than expected).

Fields of papers citing papers by Thomas A. Baillie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas A. Baillie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas A. Baillie. The network helps show where Thomas A. Baillie may publish in the future.

Co-authorship network of co-authors of Thomas A. Baillie

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas A. Baillie. A scholar is included among the top collaborators of Thomas A. Baillie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas A. Baillie. Thomas A. Baillie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Acyl glucuronides–mediators of drug-induced toxicities? 2023 ·Medicinal Chemistry Research ·Thomas A. Baillie	2
2	The contributions of Sidney D. Nelson to drug metabolism research 2014 ·Drug Metabolism Reviews ·Thomas A. Baillie	6
3	Managing the challenge of chemically reactive metabolites in drug development breakdown → 2011 ·Nature Reviews Drug Discovery ·B. Kevin Park, Alan R. Boobis, Stephen E. Clarke, Christopher E. Goldring, David Jones, J. Gerry Kenna, Craig Lambert, Hugh Laverty, Dean J. Naisbitt, Sidney D. Nelson, Deborah A. Nicoll‐Griffith, R. Scott Obach, Philip A. Routledge, Dennis A. Smith, Donald Tweedie, Nico Vermeulen, Dominic P. Williams, Ian D. Wilson, Thomas A. Baillie	338
4	Approaches for Minimizing Metabolic Activation of New Drug Candidates in Drug Discovery 2009 ·Handbook of experimental pharmacology ·Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie	16
5	Complicating factors in safety testing of drug metabolites: Kinetic differences between generated and preformed metabolites 2006 ·Toxicology and Applied Pharmacology ·Thomayant Prueksaritanont, Jiunn H. Lin, Thomas A. Baillie	50
6	Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4 2004 ·Xenobiotica ·(unknown), (unknown), Magang Shou, (unknown), Jason S. Ngui, Ralph A. Stearns, David C. Evans, Thomas A. Baillie, Wei Tang	15
7	Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate 2002 ·Drug Metabolism and Disposition ·Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol Keohane, George A. Doss, Shuet-Hing Lee Chiu, Thomas A. Baillie	8
8	Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization 2002 ·Drug Metabolism and Disposition ·Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang, Bennett Ma, Yue Qiu, Jiunn H. Lin, Paul G. Pearson, Thomas A. Baillie	276
9	CYP4 Isoenzyme Specificity and the Relationship between .omega.-Hydroxylation and Terminal Desaturation of Valproic Acid 1995 ·Biochemistry ·Allan E. Rettie, Pamela Sheffels, Kenneth R. Korzekwa, Frank J. Gonzalez, Richard M. Philpot, Thomas A. Baillie	68
10	Electrospray tandem mass spectrometry in the diagnosis of organic acidemias 1994 ·Rapid Communications in Mass Spectrometry ·M. S. Rashed, Pinar T. Ozand, Mark E. Harrison, Peter Watkins, S. Evans, Thomas A. Baillie	47
11	Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate 1994 ·Biochemical Pharmacology ·Claudia M. Jochheim, Thomas A. Baillie	31
12	A new mass spectrometric approach to detect modifications in DNA 1994 ·Rapid Communications in Mass Spectrometry ·Petra Janning, Wolfgang Schräder, Michael Linscheid, Thomas A. Baillie	37
13	Effect of carbamate thioester derivatives of methyl- and 2-chloroethyl isocyanate on glutathione levels and glutathione reductase activity in isolated rat hepatocytes 1994 ·Biochemical Pharmacology ·Kelem Kassahun, Claudia M. Jochheim, Thomas A. Baillie	17
14	Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities 1991 ·Chemical Research in Toxicology ·J. Greg Slatter, Mohamed S. Rashed, Paul G. Pearson, (unknown), Thomas A. Baillie	89
15	Oxidative metabolism of spironolactone: evidence for the involvement of electrophilic thiosteroid species in drug-mediated destruction of rat hepatic cytochrome P 450 1989 ·Biochemistry ·Caroline J. Decker, Mohamed S. Rashed, Thomas A. Baillie, David Maltby, Maria Almira Correia	20
16	The use of mass spectrometry in the study of chemically-reactive drug metabolises. Application of MS/MS and LC/MS to the analysis of glutathione- and related S-linked conjugates of N-methylformamide 1989 ·Journal of Pharmaceutical and Biomedical Analysis ·Thomas A. Baillie, Paul G. Pearson, Mohamed S. Rashed, William N. Howald	28
17	The use of alkoxycarbonyl derivatives for the mass spectral analysis of drug-thioether metabolites. Studies with the cysteine, mercapturic acid and glutathione conjugates of acetaminophen 1988 ·Journal of Mass Spectrometry ·Kurt‐Jürgen Hoffmann, Thomas A. Baillie	18
18	Enantioselective synthesis and preliminary metabolic studies of the optical isomers of 2-n-propyl-4-pentenoic acid, a hepatotoxic metabolite of valproic acid 1988 ·Chemical Research in Toxicology ·David J. Porubek, (unknown), Louis Theodore, Thomas A. Baillie	6
19	Studies on the metabolic fate of valproic acid in the rat using stable isotope techniques 1987 ·Xenobiotica ·Albert W. Rettenmeier, W. Perry Gordon, (unknown), Thomas A. Baillie	17
20	Studies on the metabolic fate of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) in man [proceedings]. 1977 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Thomas A. Baillie, Alan R. Boobis, D. S. Davies, D. H. Jones, Stephen A. Murray, John L. Reid	4

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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