Juswinder Singh

7.2k citations

57 papers · 4.9k indexed · 2 hit papers · h-index 31

Impact in

Computational Theory and Mathematics top 0.5%
- Computational Drug Discovery Methods
Physical and Theoretical Chemistry top 1%
- Crystallography and molecular interactions

Papers in

Genetics 8
- Chronic Lymphocytic Leukemia Research 8
Computational Theory and Mathematics 11
- Computational Drug Discovery Methods 11

Co-authors: Janet M. Thornton Russell C. Petter Adrian Whitty Thomas A. Baillie Claudio Chuaqui Zhan Deng Christopher A. Hunter Arthur F. Kluge
Journals: Journal of Medicinal Chemistry (7 papers)Journal of Molecular Biology (5 papers)Protein Science (4 papers)Blood (4 papers)Cancer Research (3 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Juswinder Singh

57 papers receiving 4.8k citations

Hit Papers

align trajectories log scale

The resurgence of covalent drugs 2011 · 1.4k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Nature Reviews Drug Discovery
1991 Journal of Molecular Biology

Peers

Countries citing papers authored by Juswinder Singh

Since Specialization

Citations

This map shows the geographic impact of Juswinder Singh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Juswinder Singh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Juswinder Singh more than expected).

Fields of papers citing papers by Juswinder Singh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Juswinder Singh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Juswinder Singh. The network helps show where Juswinder Singh may publish in the future.

Co-authors

The 25 scholars most cited alongside Juswinder Singh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Juswinder Singh Line = papers co-authored together Juswinder Singh links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Ascension of Targeted Covalent Inhibitors Journal of Medicinal Chemistry ·Juswinder Singh	2022	112
2	A novel Bruton’s tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity Leukemia ·Homare Eda, Loredana Santo, Diana Cirstea, Andrew J. Yee, José Gonçalves Ferreira, Neeharika Nemani, Yuko Mishima, Peter Waterman, Shirin Arastu‐Kapur, Erica N Evans, Juswinder Singh, Christopher J. Kirk, William Westlin, Noopur Raje	2014	37
3	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization Virology ·Gillian M. Schiralli Lester, Hisashi Akiyama, Erica N Evans, Juswinder Singh, Suryaram Gummuluru, Andrew J. Henderson	2012	11
4	Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine Nature Chemical Biology ·Margit Hagel, Deqiang Niu, Thia St Martin, Michael P. Sheets, Lixin Qiao, Hugues Bernard, Russell Karp, Zhendong Zhu, Matthew Labenski, Prasoon Chaturvedi, Mariana Nacht, William Westlin, Russell C. Petter, Juswinder Singh	2010	77
5	A Kinase‐focused Compound Collection: Compilation and Screening Strategy Chemical Biology & Drug Design ·Dongyu Sun, Claudio Chuaqui, Zhan Deng, Scott Bowes, Donovan N. Chin, Juswinder Singh, Patrick Cullen, Miklós Szijártó, Wen‐Cherng Lee, J.Elisabeth Donnelly, Jessica Friedman, Serene Josiah	2006	14
6	Structural Interaction Fingerprints: A New Approach to Organizing, Mining, Analyzing, and Designing Protein–Small Molecule Complexes Chemical Biology & Drug Design ·Juswinder Singh, Zhan Deng, Norfadilah Kamaruddin, Claudio Chuaqui	2005	57
7	Rational Design of Potent and Selective VLA-4 Inhibitors and their Utility in the Treatment of Asthma Current Topics in Medicinal Chemistry ·Juswinder Singh, Stephen Adams, A. Petrunkina, Hernán Cuervo, Wen‐Cherng Lee, Roy R. Lobb, R. Blake Pepinsky, Russell C. Petter, Daniel J. Scott	2004	32
8	The CRIPTO/FRL‐1/CRYPTIC (CFC) domain of human Cripto European Journal of Biochemistry ·Susan F. Foley, Herman van Vlijmen, Raymond Boynton, Heather B. Adkins, Anne E. Cheung, Juswinder Singh, Michele Sanicola, Sónia Alves, Dingyi Wen	2003	14
9	The role of polar interactions in the molecular recognition of CD40L with its receptor CD40 Protein Science ·Juswinder Singh, Ellen A. Garber, Herman van Vlijmen, Michael Karpusas, Yen‐Ming Hsu, 苏惠健, David W. Thomas, James H. Naismith	1998	60
10	Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases Journal of Medicinal Chemistry ·Juswinder Singh, Ellen M. Dobrusin, David W. Fry, Vinay Pawar, Adrian Whitty, Dennis J. McNamara	1997	89
11	X-SITE: Use of Empirically Derived Atomic Packing Preferences to Identify Favourable Interaction Regions in the Binding Sites of Proteins Journal of Molecular Biology ·Roman A. Laskowski, Janet M. Thornton, Christine Humblet, Juswinder Singh	1996	60
12	Structural Studies on the PH Domains of Dbl, Sos1, IRS-1, and .beta.ARK1 and Their Differential Binding to G.beta..gamma. Subunits Biochemistry ·Daruka Mahadevan, Narmada Thanki, Juswinder Singh, Peter McPhie, D Zangrilli, Ling-Mei Wang, Carmen Guerrero, Harry LeVine, Christine Humblet	1995	47
13	Differentiation of peptide molecular recognition by phospholipase Cγ‐1 Src homology‐2 domain and a mutant Tyr phosphatase PTP1b^C215S Protein Science ·Derek Maclean, Andrea M. Sefler, Janaina Francisca De Souza Campos Vinha, Stuart J. Decker, Alan R. Saltiel, Juswinder Singh, Dennis J. McNamara, Ellen M. Dobrusin, Tomi K. Sawyer	1995	2
14	Design of a potent peptide inhibitor of the epidermal growth factor receptor tyrosine kinase utilizing sequences based on the natural phosphorylation sites of phospholipase C-γ1 Peptides ·David W. Fry, Amy McMichael, Juswinder Singh, Ellen M. Dobrusin, Dennis J. McNamara	1994	14
15	Comparison of conservation within and between the Ser/Thr and Tyr protein kinase family: proposed model for the catalytic domain of the epidermal growth factor receptor Protein Engineering Design and Selection ·Juswinder Singh	1994	7
16	Atomic environments of arginine side chains in proteins Protein Engineering Design and Selection ·A. A. Priyomko, Juswinder Singh, Janet M. Thornton	1993	38
17	Towards an understanding of the arginine-aspartate interaction Journal of Molecular Biology ·John B. O. Mitchell, Janet M. Thornton, Juswinder Singh, Sarah L. Price	1992	88
18	SIRIUS Journal of Molecular Biology ·Juswinder Singh, Janet M. Thornton	1990	170
19	Protein engineering and design Philosophical transactions of the Royal Society of London. Series B, Biological sciences ·T.L. Blundell, Nuno Miguel Antunes da Cunha Oliveira Ramiro, Stephen P. Gardner, Tim Hubbard, Saidul Islam, Mark S. Johnson, М.І. Кісіль, Peter Murray‐Rust, John P. Overington, Jim E. Pitts, Andrej Săli, B. L. Sibanda, Juswinder Singh, Michael J.E. Sternberg, Michael J. Sutcliffe, Janet M. Thornton, Paul Travers	1989	14
20	The geometries of interacting arginine‐carboxyls in proteins FEBS Letters ·Juswinder Singh, Janet M. Thornton, M. Snarey, Simon F. Campbell	1987	89

About Juswinder Singh

Juswinder Singh is a scholar working on Genetics, Computational Theory and Mathematics, Immunology and Allergy, Molecular Biology and Oncology, having authored 57 papers that have together received 4.9k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (13 papers), Computational Drug Discovery Methods (11 papers), Monoclonal and Polyclonal Antibodies Research (9 papers), Chronic Lymphocytic Leukemia Research (8 papers), Enzyme Structure and Function (8 papers), HER2/EGFR in Cancer Research (6 papers), Click Chemistry and Applications (6 papers) and PI3K/AKT/mTOR signaling in cancer (5 papers). The work is most often cited by research in Computational Theory and Mathematics (974 citations), Physical and Theoretical Chemistry (416 citations), Molecular Biology (3.1k citations), Organic Chemistry (1.3k citations) and Genetics (414 citations). Juswinder Singh has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Janet M. Thornton, Russell C. Petter, Adrian Whitty, Thomas A. Baillie, Claudio Chuaqui, Zhan Deng, Christopher A. Hunter, Arthur F. Kluge, Herman van Vlijmen and John B. O. Mitchell. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of Molecular Biology, Protein Science, Blood and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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