Paul G. Pearson

4.1k citations

97 papers · 2.9k indexed · h-index 29

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism 18
- Drug-Induced Hepatotoxicity and Protection 5
Biochemistry top 2%
- Sulfur Compounds in Biology 11
Genetics top 5%
- Chronic Lymphocytic Leukemia Research 5
Oncology top 5%
- Drug Transport and Resistance Mechanisms 10
Cancer Research top 10%
- Carcinogens and Genotoxicity Assessment 7
Pharmaceutical Science
- Chemical Reactions and Isotopes 5
Ecology
- Wildlife Ecology and Conservation 5

Co-authors: Thomas A. Baillie Jiunn H. Lin Yue Qiu Bennett Ma Thomayant Prueksaritanont Sidney D. Nelson J. Greg Slatter Mohamed S. Rashed
Cited by: Pharmacology Biochemistry Genetics
Journals: Journal of the American Chemical Society (1 paper)Journal of Biological Chemistry (1 paper)Journal of Clinical Oncology (2 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Paul G. Pearson

93 papers receiving 2.7k citations

Peers

Countries citing papers authored by Paul G. Pearson

Since Specialization

Citations

This map shows the geographic impact of Paul G. Pearson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul G. Pearson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul G. Pearson more than expected).

Fields of papers citing papers by Paul G. Pearson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul G. Pearson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul G. Pearson. The network helps show where Paul G. Pearson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Paul G. Pearson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul G. Pearson Line = papers co-authored together Paul G. Pearson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey PLoS ONE ·Bóglárka Rácz,András Váradi,Paul G. Pearson,Konstantin Petrukhin	2020	7
2	ATR-101, a selective ACAT1 inhibitor, decreases ACTH-stimulated cortisol concentrations in dogs with naturally occurring Cushing’s syndrome BMC Endocrine Disorders ·Daniel K. Langlois,Michele C. Fritz,William D. Schall,N. Bari Olivier,Rebecca C. Smedley,Paul G. Pearson,Marc B. Bailie,S. Hunt	2018	19
3	Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Humans Drug Metabolism and Disposition ·Terry Podoll,Paul G. Pearson,Jerry Evarts,Tim Ingallinera,Елена Бибикова,Hao Sun,Mark Gohdes,Kristen A. Cardinal,Mitesh Sanghvi,J. Greg Slatter	2018	50
4	HEPATIC UPTAKE OF THE NOVEL ANTIFUNGAL AGENT CASPOFUNGIN Drug Metabolism and Disposition ·Punam Sandhu,Wooin Lee,Xin Xu,Brenda F. Leake,Masayo Yamazaki,Julie A. Stone,Jiunn H. Lin,Paul G. Pearson,Richard B. Kim	2005	83
5	EVALUATION OF MICRODOSING STRATEGIES FOR STUDIES IN PRECLINICAL DRUG DEVELOPMENT: DEMONSTRATION OF LINEAR PHARMACOKINETICS IN DOGS OF A NUCLEOSIDE ANALOG OVER A 50-FOLD DOSE RANGE Drug Metabolism and Disposition ·Punam Sandhu,John S. Vogel,Mark J. Rose,Esther A. Ubick,Janice Brunner,Michael A. Wallace,Jennifer K. Adelsberger,Maribeth P. Baker,Paul T. Henderson,Paul G. Pearson,Thomas A. Baillie	2004	45
6	Pharmacokinetics and Interactions of a Novel Antagonist of Chemokine Receptor 5 (CCR5) with Ritonavir in Rats and Monkeys: Role of CYP3A and P-Glycoprotein Journal of Pharmacology and Experimental Therapeutics ·Sanjeev Kumar,Gloria Y. Kwei,Grace K. Poon,Susan A. Iliff,Yanfeng Wang,Qing Chen,Ronald B. Franklin,Varsha Didolkar,Regina W. Wang,Masayo Yamazaki,Shuet-Hing Lee Chiu,Jiunn H. Lin,Paul G. Pearson,Thomas A. Baillie	2003	19
7	Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization Drug Metabolism and Disposition ·Thomayant Prueksaritanont,Raju Subramanian,Xiaojun Fang,Bennett Ma,Yue Qiu,Jiunn H. Lin,Paul G. Pearson,Thomas A. Baillie	2002	276
8	Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins Journal of Pharmacology and Experimental Therapeutics ·Thomayant Prueksaritanont,Jamie J. Zhao,Bennett Ma,Brad Roadcap,Cuyue Tang,Yue Qiu,Lida Liu,Jiunn H. Lin,Paul G. Pearson,Thomas A. Baillie	2002	219
9	Biotransformation of tirilazad in human: 1. Cytochrome P450 3A-mediated hydroxylation of tirilazad mesylate in human liver microsomes. Journal of Pharmacology and Experimental Therapeutics ·Larry C. Wienkers,Rick C. Steenwyk,P E Sanders,Paul G. Pearson	1996	37
10	Biotransformation of tirilazad in human: 2. Effect of ketoconazole on tirilazad clearance and oral bioavailability. Journal of Pharmacology and Experimental Therapeutics ·Joseph C. Fleishaker,Paul G. Pearson,Larry C. Wienkers,Laura Pearson,Gary Peters	1996	22
11	In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase. Drug Metabolism and Disposition ·Larry C. Wienkers,Rick C. Steenwyk,S. A. MIZSAK,Paul G. Pearson	1995	19
12	Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities Chemical Research in Toxicology ·J. Greg Slatter,Mohamed S. Rashed,Paul G. Pearson,Deog Hwa Han,Thomas A. Baillie	1991	89
13	2-amino-3-(methylamino)-propanoic acid (BMAA) pharmacokinetics and blood-brain barrier permeability in the rat. Journal of Pharmacology and Experimental Therapeutics ·Mark W. Duncan,Nelly E. Villacreses,Paul G. Pearson,Linden C. Wyatt,С. И. Рапопорт,I J Kopin,Sanford P. Markey,Quentin R. Smith	1991	77
14	Carbamoylation of peptides and proteins in vitro by S-(N-methylcarbamoyl)glutathione and S-(N-methylcarbamoyl)cysteine, two electrophilic S-linked conjugates of methyl isocyanate Chemical Research in Toxicology ·Paul G. Pearson,J. Greg Slatter,Mohamed S. Rashed,Deog Hwa Han,Thomas A. Baillie	1991	47
15	S-(N-Methylcarbamoyl)glutathione: A reactive S-linked metabolite of methyl isocyanate Biochemical and Biophysical Research Communications ·Paul G. Pearson,J. Greg Slatter,Mohamed S. Rashed,Deog-Hwa Han,Mark P. Grillo,Thomas A. Baillie	1990	52
16	Metabolic activation of 1,2-dibromo-3-chloropropane: evidence for the formation of reactive episulfonium ion intermediates Biochemistry ·Paul G. Pearson,Erik J. Søderlund,Erik Dybing,Sidney D. Nelson	1990	38
17	Chemical synthesis and cytotoxic properties of N-alkylcarbamic acid thioesters, metabolites of hepatotoxic formamides Chemical Research in Toxicology ·Deog Hwa Han,Paul G. Pearson,Thomas A. Baillie,Renuka Dayal,Lincoln H. Tsang,Andreas Gescher	1990	17
18	Metabolic activation of 1,2-dibromo-3-chloropropane to mutagenic metabolites: detection and mechanism of formation of (Z)- and (E)-2-chloro-3-(bromomethyl) oxirane Chemical Research in Toxicology ·Paul G. Pearson,James G. Omichinski,Timothy G. Myers,Erik J. Soederlund,Erik Dybing,Sidney D. Nelson	1990	18
19	Formation of cyclic 1,N2-propanodeoxyguanosine and thymidine adducts in the reaction of the mutagen 2-bromoacrolein with calf thymus DNA. PubMed ·John H.N. Meerman,Toby R. Smith,Paul G. Pearson,G. Patrick Meier,Sidney D. Nelson	1989	16
20	The use of mass spectrometry in the study of chemically-reactive drug metabolises. Application of MS/MS and LC/MS to the analysis of glutathione- and related S-linked conjugates of N-methylformamide Journal of Pharmaceutical and Biomedical Analysis ·Thomas A. Baillie,Paul G. Pearson,Mohamed S. Rashed,William N. Howald	1989	28

About Paul G. Pearson

Paul G. Pearson is a scholar working on Pharmacology, Biochemistry and Pharmaceutical Science, having authored 97 papers that have together received 2.9k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (18 papers), Sulfur Compounds in Biology (11 papers), Drug Transport and Resistance Mechanisms (10 papers), Carcinogens and Genotoxicity Assessment (7 papers), Chronic Lymphocytic Leukemia Research (5 papers), Chemical Reactions and Isotopes (5 papers), Drug-Induced Hepatotoxicity and Protection (5 papers) and Wildlife Ecology and Conservation (5 papers). The work is most often cited by research in Pharmacology (650 citations), Biochemistry (209 citations) and Genetics (277 citations). Paul G. Pearson has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Thomas A. Baillie, Jiunn H. Lin, Yue Qiu, Bennett Ma, Thomayant Prueksaritanont, Sidney D. Nelson, J. Greg Slatter, Mohamed S. Rashed, Xiaojun Fang and Raju Subramanian. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Journal of Clinical Oncology.

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