T.L. Poulos

30.9k total citations · 9 hit papers
338 papers, 25.1k citations indexed

About

T.L. Poulos is a scholar working on Molecular Biology, Inorganic Chemistry and Physiology. According to data from OpenAlex, T.L. Poulos has authored 338 papers receiving a total of 25.1k indexed citations (citations by other indexed papers that have themselves been cited), including 152 papers in Molecular Biology, 89 papers in Inorganic Chemistry and 86 papers in Physiology. Recurrent topics in T.L. Poulos's work include Metal-Catalyzed Oxygenation Mechanisms (87 papers), Nitric Oxide and Endothelin Effects (83 papers) and Pharmacogenetics and Drug Metabolism (83 papers). T.L. Poulos is often cited by papers focused on Metal-Catalyzed Oxygenation Mechanisms (87 papers), Nitric Oxide and Endothelin Effects (83 papers) and Pharmacogenetics and Drug Metabolism (83 papers). T.L. Poulos collaborates with scholars based in United States, Czechia and United Kingdom. T.L. Poulos's co-authors include B.C. Finzel, J. Kraut, Andrew Howard, Irina F. Sevrioukova, Huiying Li, Reetta Raag, David J. Schuller, Michael H. Gold, S.L. Edwards and Huiying Li and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

T.L. Poulos

335 papers receiving 24.5k citations

Hit Papers

High-resolution crystal structure of cytochrome P450cam 1980 2026 1995 2010 1987 2014 1985 1984 1997 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. High-resolution crystal structure of cytochrome P450cam
    1987 1.2k citations T.L. Poulos, B.C. Finzel et al. Journal of Molecular Biology profile →
  2. Heme Enzyme Structure and Function
    2014 1.1k citations T.L. Poulos profile →
  3. The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450.
    1985 683 citations T.L. Poulos, B.C. Finzel et al. Journal of Biological Chemistry profile →
  4. Crystal structure of yeast cytochrome c peroxidase refined at 1.7-A resolution.
    1984 616 citations B.C. Finzel, T.L. Poulos et al. Journal of Biological Chemistry profile →
  5. Crystal structure of horseradish peroxidase C at 2.15 Å resolution
    1997 606 citations T.L. Poulos et al. profile →
  6. The stereochemistry of peroxidase catalysis.
    1980 554 citations T.L. Poulos et al. Journal of Biological Chemistry profile →
  7. Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
    2012 521 citations T.L. Poulos et al. profile →
  8. Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase
    1998 508 citations Huiying Li, Pavel Martásek et al. profile →
  9. The use of an imaging proportional counter in macromolecular crystallography
    1987 470 citations Andrew Howard, B.C. Finzel et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
T.L. Poulos United States 75 13.0k 6.2k 5.4k 4.4k 3.2k 338 25.1k
Paul R. Ortiz de Montellano United States 66 9.1k 0.7× 4.3k 0.7× 3.6k 0.7× 3.2k 0.7× 1.7k 0.5× 325 16.9k
Stephen G. Sligar United States 89 19.0k 1.5× 7.1k 1.1× 6.3k 1.2× 6.8k 1.6× 4.1k 1.3× 385 31.9k
Minor J. Coon United States 77 10.8k 0.8× 12.4k 2.0× 2.7k 0.5× 1.8k 0.4× 1.1k 0.3× 257 24.0k
Ilme Schlichting Germany 66 9.3k 0.7× 1.4k 0.2× 2.3k 0.4× 2.4k 0.5× 4.0k 1.2× 174 14.8k
Daniel Mansuy France 68 4.2k 0.3× 3.5k 0.6× 4.3k 0.8× 876 0.2× 4.8k 1.5× 420 16.1k
I. C. Gunsalus United States 61 9.7k 0.7× 6.0k 1.0× 1.8k 0.3× 2.5k 0.6× 1.4k 0.4× 188 17.8k
Herbert Waldmann Germany 95 23.3k 1.8× 1.2k 0.2× 1.7k 0.3× 3.3k 0.7× 1.6k 0.5× 840 38.6k
John H. Dawson United States 47 5.1k 0.4× 1.6k 0.3× 4.8k 0.9× 2.7k 0.6× 2.3k 0.7× 200 10.3k
E. J. Corey United States 128 21.9k 1.7× 2.6k 0.4× 10.2k 1.9× 878 0.2× 3.3k 1.0× 995 75.7k
John R. Falck United States 109 14.5k 1.1× 6.7k 1.1× 1.1k 0.2× 2.3k 0.5× 360 0.1× 892 46.6k

Countries citing papers authored by T.L. Poulos

Since Specialization
Citations

This map shows the geographic impact of T.L. Poulos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by T.L. Poulos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites T.L. Poulos more than expected).

Fields of papers citing papers by T.L. Poulos

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by T.L. Poulos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by T.L. Poulos. The network helps show where T.L. Poulos may publish in the future.

Co-authorship network of co-authors of T.L. Poulos

This figure shows the co-authorship network connecting the top 25 collaborators of T.L. Poulos. A scholar is included among the top collaborators of T.L. Poulos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with T.L. Poulos. T.L. Poulos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lamb, David C., et al.. (2025). Crystal structure of cytochrome P450 NysL and the structural basis for stereo- and regio-selective oxidation of antifungal macrolides. Journal of Biological Chemistry. 301(3). 108185–108185.
2.
Li, Huiying, Christine D. Hardy, Qing Jing, et al.. (2024). Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry. 63(6). 788–796. 3 indexed citations
3.
Muldoon, Jimmy, Paul Evans, Y. Ortin, et al.. (2024). Biosynthesis of a new skyllamycin in Streptomyces nodosus: a cytochrome P450 forms an epoxide in the cinnamoyl chain. Organic & Biomolecular Chemistry. 22(14). 2835–2843. 1 indexed citations
4.
Vasu, Dhananjayan, Ha T., Huiying Li, et al.. (2023). Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. Journal of Medicinal Chemistry. 66(14). 9934–9953. 6 indexed citations
5.
Batabyal, Dipanwita & T.L. Poulos. (2018). Effect of redox partner binding on CYP101D1 conformational dynamics. Journal of Inorganic Biochemistry. 183. 179–183. 2 indexed citations
6.
Lewis-Ballester, Ariel, et al.. (2018). Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1. Journal of the American Chemical Society. 140(27). 8518–8525. 38 indexed citations
7.
Tripathi, Sarvind, et al.. (2017). Dissecting binding of a β-barrel membrane protein by phage display. Molecular BioSystems. 13(8). 1438–1447. 2 indexed citations
8.
Tripathi, Sarvind, Huiying Li, & T.L. Poulos. (2013). Structural Basis for Effector Control and Redox Partner Recognition in Cytochrome P450. Science. 340(6137). 1227–1230. 148 indexed citations
9.
Xue, Fengtian, Huiying Li, S.L. Delker, et al.. (2010). Potent, Highly Selective, and Orally Bioavailable Gem -Difluorinated Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Journal of the American Chemical Society. 132(40). 14229–14238. 62 indexed citations
10.
Sevrioukova, Irina F. & T.L. Poulos. (2010). Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir. Proceedings of the National Academy of Sciences. 107(43). 18422–18427. 227 indexed citations
11.
Poulos, T.L.. (2010). Thirty years of heme peroxidase structural biology. Archives of Biochemistry and Biophysics. 500(1). 3–12. 98 indexed citations
12.
Sevrioukova, Irina F. & T.L. Poulos. (2010). Structural biology of redox partner interactions in P450cam monooxygenase: A fresh look at an old system. Archives of Biochemistry and Biophysics. 507(1). 66–74. 43 indexed citations
13.
Poulos, T.L.. (2005). Intermediates in P450 catalysis. Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences. 363(1829). 793–806. 32 indexed citations
14.
Guo, Maolin, et al.. (2004). Crystal structure and characterization of a cytochrome c peroxidase–cytochrome c site-specific cross-link. Proceedings of the National Academy of Sciences. 101(16). 5940–5945. 46 indexed citations
15.
Bretscher, Lynn E., Huiying Li, T.L. Poulos, & Owen W. Griffith. (2003). Structural Characterization and Kinetics of Nitric-oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-ornithines. Journal of Biological Chemistry. 278(47). 46789–46797. 32 indexed citations
16.
Webster, Scott D., Andrea J. Tenner, T.L. Poulos, & David H. Cribbs. (1999). The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation☆. Neurobiology of Aging. 20(3). 297–304. 38 indexed citations
17.
Yeom, Hyeyeong, Stephen G. Sligar, Huiying Li, T.L. Poulos, & Armand J. Fulco. (1995). The role of Thr268 in oxygen activation of cytochrome P450BM-3. Biochemistry. 34(45). 14733–14740. 138 indexed citations
18.
Edwards, S.L., Reetta Raag, Hiroyuki Wariishi, Michael H. Gold, & T.L. Poulos. (1993). Crystal structure of lignin peroxidase.. Proceedings of the National Academy of Sciences. 90(2). 750–754. 139 indexed citations
19.
Poulos, T.L.. (1991). [2] Modeling of mammalian P450s on basis of P450cam x-ray structure. Methods in enzymology on CD-ROM/Methods in enzymology. 206. 11–30. 57 indexed citations
20.
Poulos, T.L., B.C. Finzel, & Andrew Howard. (1987). High-resolution crystal structure of cytochrome P450cam. Journal of Molecular Biology. 195(3). 687–700. 1169 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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