Caroline J. Decker

3.7k total citations · 1 hit paper
17 papers, 1.6k citations indexed

About

Caroline J. Decker is a scholar working on Pharmacology, Oncology and Molecular Biology. According to data from OpenAlex, Caroline J. Decker has authored 17 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 6 papers in Pharmacology, 5 papers in Oncology and 3 papers in Molecular Biology. Recurrent topics in Caroline J. Decker's work include Pharmacogenetics and Drug Metabolism (6 papers), Drug Transport and Resistance Mechanisms (4 papers) and Analytical Chemistry and Chromatography (2 papers). Caroline J. Decker is often cited by papers focused on Pharmacogenetics and Drug Metabolism (6 papers), Drug Transport and Resistance Mechanisms (4 papers) and Analytical Chemistry and Chromatography (2 papers). Caroline J. Decker collaborates with scholars based in United States. Caroline J. Decker's co-authors include Peter D. J. Grootenhuis, Sabine Hadidaꝉ, Fredrick Van Goor, Paul A. Negulescu, Eric R. Olson, Jeffrey J. Wine, Jeffrey H. Stack, Bill Burton, Mark A. Miller and Kimberly Straley and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Biochemistry and Biochemical and Biophysical Research Communications.

In The Last Decade

Caroline J. Decker

17 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

2011 831 citations Fredrick Van Goor, Sabine Hadidaꝉ et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Caroline J. Decker United States	15	733	635	174	151	135	17	1.6k
Akira Ueno Japan	24	440 0.6×	579 0.9×	193 1.1×	48 0.3×	83 0.6×	137	1.9k
Toshikazu Hada Japan	27	191 0.3×	885 1.4×	143 0.8×	199 1.3×	294 2.2×	116	2.2k
Lori D. Dwyer‐Nield United States	27	494 0.7×	1.3k 2.0×	86 0.5×	495 3.3×	496 3.7×	60	2.4k
John C. Marecki United States	18	356 0.5×	460 0.7×	109 0.6×	100 0.7×	106 0.8×	30	1.5k
J. Masliah France	27	262 0.4×	905 1.4×	58 0.3×	251 1.7×	259 1.9×	61	2.0k
Stuart L. Bursten United States	23	175 0.2×	991 1.6×	78 0.4×	260 1.7×	314 2.3×	36	1.7k
Amjad Khan United Kingdom	22	233 0.3×	567 0.9×	68 0.4×	71 0.5×	63 0.5×	72	1.5k
Bo Odlind Sweden	21	189 0.3×	287 0.5×	148 0.9×	178 1.2×	171 1.3×	56	1.4k
Fernando Gómez Spain	18	174 0.2×	857 1.3×	45 0.3×	163 1.1×	63 0.5×	56	1.5k
Iain Kilty United Kingdom	25	557 0.8×	713 1.1×	34 0.2×	195 1.3×	426 3.2×	40	1.9k

Countries citing papers authored by Caroline J. Decker

Since Specialization

Citations

This map shows the geographic impact of Caroline J. Decker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Caroline J. Decker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Caroline J. Decker more than expected).

Fields of papers citing papers by Caroline J. Decker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Caroline J. Decker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Caroline J. Decker. The network helps show where Caroline J. Decker may publish in the future.

Co-authorship network of co-authors of Caroline J. Decker

This figure shows the co-authorship network connecting the top 25 collaborators of Caroline J. Decker. A scholar is included among the top collaborators of Caroline J. Decker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Caroline J. Decker. Caroline J. Decker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Anderson, Corey L., Sabine Hadidaꝉ, Sanghee Yoo, et al.. (2014). Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 24(3). 845–849. 20 indexed citations

Hadidaꝉ, Sabine, Fredrick Van Goor, Jinglan Zhou, et al.. (2014). Discovery of N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, Ivacaftor), a Potent and Orally Bioavailable CFTR Potentiator. Journal of Medicinal Chemistry. 57(23). 9776–9795. 77 indexed citations

Goor, Fredrick Van, Sabine Hadidaꝉ, Peter D. J. Grootenhuis, et al.. (2011). Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809. Proceedings of the National Academy of Sciences. 108(46). 18843–18848. 831 indexed citations breakdown →

Leeuwen, Jolanda van, Yongmin Li, Peter D. J. Grootenhuis, et al.. (2011). Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space. Drug Metabolism and Disposition. 39(9). 1568–1576. 40 indexed citations

Namchuk, Mark, John R. Pollard, Pamella J. Ford, et al.. (2007). (S)-1-((S)-2-{[1-(4-Amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2 R,3 S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an Orally Available Selective Interleukin (IL)-Converting Enzyme/Caspase-1 Inhibitor, Exhibits Potent Anti-Inflammatory Activities by Inhibiting the Release of IL-1β and IL-18. Journal of Pharmacology and Experimental Therapeutics. 321(2). 509–516. 250 indexed citations

Jain, Jugnu, et al.. (2002). Characterization of Pharmacological Efficacy of VX-148, a New, Potent Immunosuppressive Inosine 5′-Monophosphate Dehydrogenase Inhibitor. Journal of Pharmacology and Experimental Therapeutics. 302(3). 1272–1277. 24 indexed citations

Chaturvedi, Pravin, Caroline J. Decker, & Aleksandrs Odinecs. (2001). Prediction of pharmacokinetic properties using experimental approaches during early drug discovery. Current Opinion in Chemical Biology. 5(4). 452–463. 81 indexed citations

Decker, Caroline J., et al.. (1999). THE NOVEL IMPDH INHIBITOR VX-497 PROLONGS SKIN GRAFT SURVIVAL AND IMPROVES GVHD IN MOUSE. Transplantation. 67(7). S57–S57. 1 indexed citations

Decker, Caroline J., et al.. (1998). Metabolism of Amprenavir in Liver Microsomes: Role of CYP3A4 Inhibition for Drug Interactions. Journal of Pharmaceutical Sciences. 87(7). 803–807. 92 indexed citations

10.

Doerge, Daniel R. & Caroline J. Decker. (1994). Inhibition of Peroxidase-Catalyzed Reactions by Arylamines: Mechanism for the Anti-Thyroid Action of Sulfamethazine. Chemical Research in Toxicology. 7(2). 164–169. 43 indexed citations

11.

Doerge, Daniel R., et al.. (1993). Chemical and enzymic oxidation of benzimidazoline-2-thiones: a dichotomy in the mechanism of peroxidase inhibition. Biochemistry. 32(1). 58–65. 28 indexed citations

12.

Decker, Caroline J. & Daniel R. Doerge. (1992). Covalent binding of 14C- and 35S-labeled thiocarbamides in rat hepatic microsomes. Biochemical Pharmacology. 43(4). 881–888. 21 indexed citations

13.

Decker, Caroline J., John R. Cashman, Katsumi Sugiyama, David Maltby, & Maria Almira Correia. (1991). Formation of glutathionyl-spironolactone disulfide by rat liver cytochromes P450 or hog liver flavin-containing monooxygenases: a functional probe of two-electron oxidations of the thiosteroid?. Chemical Research in Toxicology. 4(6). 669–677. 12 indexed citations

14.

Decker, Caroline J. & Daniel R. Doerge. (1991). Rat hepatic microsomal metabolism of ethylenethiourea. Contributions of the flavin-containing monooxygenase and cytochrome P-450 isozymes. Chemical Research in Toxicology. 4(4). 482–489. 16 indexed citations

15.

Decker, Caroline J., Mohamed S. Rashed, Thomas A. Baillie, David Maltby, & Maria Almira Correia. (1989). Oxidative metabolism of spironolactone: evidence for the involvement of electrophilic thiosteroid species in drug-mediated destruction of rat hepatic cytochrome P 450. Biochemistry. 28(12). 5128–5136. 20 indexed citations

16.

Correia, Maria Almira, Caroline J. Decker, Katsumi Sugiyama, et al.. (1987). Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2, 6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts. Archives of Biochemistry and Biophysics. 258(2). 436–451. 57 indexed citations

17.

Decker, Caroline J., Katsumi Sugiyama, Mark D. Underwood, & Maria Almira Correia. (1986). Inactivation of rat hepatic cytochrome P-450 by spironolactone. Biochemical and Biophysical Research Communications. 136(3). 1162–1169. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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