Stephen E. Clarke

3.1k total citations · 1 hit paper
42 papers, 2.3k citations indexed

About

Stephen E. Clarke is a scholar working on Pharmacology, Molecular Biology and Cognitive Neuroscience. According to data from OpenAlex, Stephen E. Clarke has authored 42 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Pharmacology, 12 papers in Molecular Biology and 8 papers in Cognitive Neuroscience. Recurrent topics in Stephen E. Clarke's work include Pharmacogenetics and Drug Metabolism (14 papers), Neural dynamics and brain function (8 papers) and Drug Transport and Resistance Mechanisms (6 papers). Stephen E. Clarke is often cited by papers focused on Pharmacogenetics and Drug Metabolism (14 papers), Neural dynamics and brain function (8 papers) and Drug Transport and Resistance Mechanisms (6 papers). Stephen E. Clarke collaborates with scholars based in United Kingdom, United States and Canada. Stephen E. Clarke's co-authors include J. Brian Houston, Aleksandra Galetin, Harriet G. Oldham, Leonard Maler, Dean J. Naisbitt, Christine Beedham, André Longtin, J. Andrews, Kathryn E. Kenworthy and John A. Smith and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Communications and Journal of Neuroscience.

In The Last Decade

Stephen E. Clarke

41 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Managing the challenge of chemically reactive metabolites in drug development

2011 338 citations B. Kevin Park, Alan R. Boobis et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Stephen E. Clarke United Kingdom	22	926	701	403	351	344	42	2.3k
Cuyue Tang United States	25	839 0.9×	631 0.9×	278 0.7×	627 1.8×	162 0.5×	66	2.2k
Christopher L. Shaffer United States	23	357 0.4×	780 1.1×	286 0.7×	207 0.6×	386 1.1×	56	1.8k
Claire Mackie Belgium	25	490 0.5×	793 1.1×	216 0.5×	394 1.1×	371 1.1×	49	2.0k
Dennis O. Scott United States	26	488 0.5×	638 0.9×	560 1.4×	621 1.8×	223 0.6×	51	2.1k
Margaret R. Davis United States	27	422 0.5×	731 1.0×	211 0.5×	188 0.5×	371 1.1×	48	2.5k
Tristan S. Maurer United States	29	998 1.1×	908 1.3×	289 0.7×	1.1k 3.2×	282 0.8×	64	2.9k
Krista Laine Finland	26	364 0.4×	602 0.9×	569 1.4×	496 1.4×	310 0.9×	44	2.1k
Izet M. Kapetanović United States	28	283 0.3×	1.1k 1.6×	206 0.5×	310 0.9×	337 1.0×	94	2.8k
Ryuji Kato Japan	29	1.2k 1.3×	1.4k 2.0×	320 0.8×	472 1.3×	400 1.2×	127	3.5k
Travis T. Wager United States	29	437 0.5×	1.7k 2.4×	484 1.2×	419 1.2×	545 1.6×	42	3.9k

Countries citing papers authored by Stephen E. Clarke

Since Specialization

Citations

This map shows the geographic impact of Stephen E. Clarke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen E. Clarke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen E. Clarke more than expected).

Fields of papers citing papers by Stephen E. Clarke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen E. Clarke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen E. Clarke. The network helps show where Stephen E. Clarke may publish in the future.

Co-authorship network of co-authors of Stephen E. Clarke

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen E. Clarke. A scholar is included among the top collaborators of Stephen E. Clarke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen E. Clarke. Stephen E. Clarke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Clarke, Stephen E., et al.. (2024). Neuroelectrophysiology-compatible electrolytic lesioning. eLife. 12.

Clarke, Stephen E., et al.. (2023). Neuroelectrophysiology-compatible electrolytic lesioning. eLife. 12. 1 indexed citations

Clarke, Stephen E., et al.. (2019). Cellular and Network Mechanisms May Generate Sparse Coding of Sequential Object Encounters in Hippocampal-Like Circuits. eNeuro. 6(4). ENEURO.0108–19.2019. 10 indexed citations

Clarke, Stephen E. & Leonard Maler. (2017). Feedback Synthesizes Neural Codes for Motion. Current Biology. 27(9). 1356–1361. 34 indexed citations

Clarke, Stephen E., André Longtin, & Leonard Maler. (2015). The neural dynamics of sensory focus. Nature Communications. 6(1). 8764–8764. 19 indexed citations

Naisbitt, Dean J., Neil G. Berry, Alexandre S. Lawrenson, et al.. (2015). Towards depersonalized abacavir therapy. AIDS. 29(18). 2385–2395. 13 indexed citations

Clarke, Stephen E., Richard Naud, André Longtin, & Leonard Maler. (2013). Speed-invariant encoding of looming object distance requires power law spike rate adaptation. Proceedings of the National Academy of Sciences. 110(33). 13624–13629. 21 indexed citations

Park, B. Kevin, Alan R. Boobis, Stephen E. Clarke, et al.. (2011). Managing the challenge of chemically reactive metabolites in drug development. Nature Reviews Drug Discovery. 10(4). 292–306. 338 indexed citations breakdown →

Reese, Melinda J., Jeffrey L. Ambroso, Andrew W. Harrell, et al.. (2010). An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development. Chemico-Biological Interactions. 192(1-2). 60–64. 21 indexed citations

10.

Sanderson, Joseph P., et al.. (2008). Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites. Drug Metabolism and Disposition. 36(12). 2424–2428. 6 indexed citations

11.

Wu, Ying, Joseph P. Sanderson, John Farrell, et al.. (2006). Activation of T cells by carbamazepine and carbamazepine metabolites. Journal of Allergy and Clinical Immunology. 118(1). 233–241. 106 indexed citations

12.

Galetin, Aleksandra, Stephen E. Clarke, & J. Brian Houston. (2003). MULTISITE KINETIC ANALYSIS OF INTERACTIONS BETWEEN PROTOTYPICAL CYP3A4 SUBGROUP SUBSTRATES: MIDAZOLAM, TESTOSTERONE, AND NIFEDIPINE. Drug Metabolism and Disposition. 31(9). 1108–1116. 116 indexed citations

13.

Bromidge, Steven M., Stephen E. Clarke, Frank D. King, et al.. (2002). Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 12(10). 1357–1360. 12 indexed citations

14.

Galetin, Aleksandra, Stephen E. Clarke, & J. Brian Houston. (2002). Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach. Drug Metabolism and Disposition. 30(12). 1512–1522. 85 indexed citations

15.

Bromidge, Steven M., Stephen E. Clarke, Tracey Gager, et al.. (2001). Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134). Bioorganic & Medicinal Chemistry Letters. 11(1). 55–58. 47 indexed citations

16.

Routledge, Carol, Steven M. Bromidge, Stephen F. Moss, et al.. (2000). Characterization of SB‐271046: A potent, selective and orally active 5‐HT₆ receptor antagonist. British Journal of Pharmacology. 130(7). 1606–1612. 119 indexed citations

17.

Giddings, Stephen J., Stephen E. Clarke, & G. Gordon Gibson. (1997). CYP4A1 gene transfection studies and the peroxisome proliferator-activated receptor: development of a high-throughput assay to detect peroxisome proliferators. European Journal of Drug Metabolism and Pharmacokinetics. 22(4). 315–319. 7 indexed citations

18.

Harrell, Andrew W., et al.. (1993). Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.. Drug Metabolism and Disposition. 21(1). 18–23. 16 indexed citations

19.

Ahmad, Abdalqader, Stephen E. Clarke, A. Buchan, & G. R. B. Skinner. (1990). Sequential release of antigens from chloroform‐treated Staphylococcus epidermidis : application towards a possible vaccine. Journal of Applied Bacteriology. 69(5). 676–685. 1 indexed citations

20.

Clarke, Stephen E., Clive Brealey, & G. Gordon Gibson. (1989). Cytochrome P-450 in the housefly: Induction, substrate specificity and comparison to three rat hepatic isoenzymes. Xenobiotica. 19(10). 1175–1180. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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