Adrian Whitty

8.9k total citations · 1 hit paper
78 papers, 6.9k citations indexed

About

Adrian Whitty is a scholar working on Molecular Biology, Immunology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Adrian Whitty has authored 78 papers receiving a total of 6.9k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Molecular Biology, 22 papers in Immunology and 19 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Adrian Whitty's work include Monoclonal and Polyclonal Antibodies Research (19 papers), Computational Drug Discovery Methods (18 papers) and Protein Structure and Dynamics (11 papers). Adrian Whitty is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (19 papers), Computational Drug Discovery Methods (18 papers) and Protein Structure and Dynamics (11 papers). Adrian Whitty collaborates with scholars based in United States, Canada and United Kingdom. Adrian Whitty's co-authors include Juswinder Singh, Russell C. Petter, Thomas A. Baillie, Sándor Vajda, Dmitri Beglov, Dima Kozakov, R. Blake Pepinsky, Peter J. Tonge, Eric S. Day and Richa Rawat and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Adrian Whitty

77 papers receiving 6.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The resurgence of covalent drugs

2011 1.4k citations Juswinder Singh, Adrian Whitty et al. profile →

Peers

Countries citing papers authored by Adrian Whitty

Since Specialization

Citations

This map shows the geographic impact of Adrian Whitty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adrian Whitty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adrian Whitty more than expected).

Fields of papers citing papers by Adrian Whitty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adrian Whitty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adrian Whitty. The network helps show where Adrian Whitty may publish in the future.

Co-authorship network of co-authors of Adrian Whitty

This figure shows the co-authorship network connecting the top 25 collaborators of Adrian Whitty. A scholar is included among the top collaborators of Adrian Whitty based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Adrian Whitty. Adrian Whitty is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Macrocycles for Conventionally Druggable Targets: Lessons from Macrocyclic Kinase Inhibitors 2025 ·Journal of Medicinal Chemistry ·Lauren A. Viarengo‐Baker, Adrian Whitty	1
2	A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells 2025 ·Nature Communications ·(unknown), (unknown), (unknown), Usha Singh, (unknown), James D. Vasta, Michael Beck, Jennifer Wilkinson, Jennifer Ward, Catherine Rogers, (unknown), (unknown), Jesper S. Hansen, P. Loppnau, Adrian Whitty, Paul E. Brennan, Peter J. Tonge, Matthew B. Robers, K. Huber	0
3	Exploring the structural origins of cryptic sites on proteins 2018 ·Proceedings of the National Academy of Sciences ·Dmitri Beglov, David Hall, Amanda Wakefield, Lingqi Luo, Karen N. Allen, Dima Kozakov, Adrian Whitty, Sándor Vajda	93
4	Cryptic binding sites on proteins: definition, detection, and druggability 2018 ·Current Opinion in Chemical Biology ·Sándor Vajda, Dmitri Beglov, Amanda Wakefield, Megan Egbert, Adrian Whitty	114
5	Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs 2016 ·Drug Discovery Today ·Adrian Whitty, Mengqi Zhong, Lauren A. Viarengo‐Baker, Dmitri Beglov, David Hall, Sándor Vajda	203
6	Ligand deconstruction: Why some fragment binding positions are conserved and others are not 2015 ·Proceedings of the National Academy of Sciences ·Dima Kozakov, David R. Hall, Stefan Jehle, Lingqi Luo, Stefan O. Ochiana, (unknown), Michael P. Pollastri, Karen N. Allen, Adrian Whitty, Sándor Vajda	56
7	Determining the affinity and stoichiometry of interactions between unmodified proteins in solution using Biacore 2013 ·Analytical Biochemistry ·Eric S. Day, Allan D. Capili, Christopher W. Borysenko, Mohammad Zafari, Adrian Whitty	15
8	Understanding cytokine and growth factor receptor activation mechanisms 2012 ·Critical Reviews in Biochemistry and Molecular Biology ·(unknown), Adrian Whitty	69
9	Identification and Characterization of Kava‐derived Compounds Mediating TNF‐α Suppression 2009 ·Chemical Biology & Drug Design ·Michael P. Pollastri, Adrian Whitty, (unknown), Xiaoou Tang, Trent D. Ashton, Salomon Amar	25
10	Cooperativity and biological complexity 2008 ·Nature Chemical Biology ·Adrian Whitty	238
11	Comparison of Soluble Decoy IgG Fusion Proteins of BAFF-R and BCMA as Antagonists for BAFF 2003 ·Journal of Biological Chemistry ·Marc R. Pelletier, Jeffrey S. Thompson, Fang Qian, Sarah A. Bixler, (unknown), Teresa G. Cachero, Kevin Gilbride, Eric S. Day, Mohammad Zafari, (unknown), Leonid Gorelik, Adrian Whitty, Susan L. Kalled, Christine Ambrose, Yen‐Ming Hsu	79
12	Comparison of Gene Expression Patterns Induced by Treatment of Human Umbilical Vein Endothelial Cells with IFN- α 2b vs. IFN- β 1a: Understanding the Functional Relationship Between Distinct Type I Interferons That Act Through a Common Receptor 2002 ·Journal of Interferon & Cytokine Research ·(unknown), Margot Brickelmaier, Gerard R. Majeau, A. V. Lukashin, (unknown), Adrian Whitty, Paula S. Hochman	58
13	Stereoselectivity of Enoyl-CoA Hydratase Results from Preferential Activation of One of Two Bound Substrate Conformers 2002 ·Chemistry & Biology ·Alasdair F. Bell, (unknown), (unknown), (unknown), Jiaquan Wu, M. Rudolph, Caroline Kisker, Adrian Whitty, Peter J. Tonge	24
14	Mapping of IFN-β Epitopes Important for Receptor Binding and Biologic Activation: Comparison of Results Achieved Using Antibody-Based Methods and Alanine Substitution Mutagenesis 2001 ·Journal of Interferon & Cytokine Research ·Laura Runkel, (unknown), Michael Karpusas, Darren P. Baker, Zhifang Li, Mohammad Zafari, Matthew J. Betzenhauser, (unknown), Stephan Miller, Philip N. Redlich, Sidney E. Grossberg, Adrian Whitty, Paula S. Hochman	22
15	The immunological synapse and CD28-CD80 interactions 2001 ·Nature Immunology ·Shannon K. Bromley, Andrea Iaboni, Simon J. Davis, Adrian Whitty, Jonathan M. Green, Andréy S. Shaw, Arthur Weiss, Michael L. Dustin	240
16	The structure of human interferon- ? : implications for activity 1998 ·Cellular and Molecular Life Sciences ·Michael Karpusas, Adrian Whitty, Laura Runkel, Paula S. Hochman	89
17	Inhibitory Specificity of the Anti-inflammatory Myxoma Virus Serpin, SERP-1 1998 ·Journal of Biological Chemistry ·Piers Nash, Adrian Whitty, Jason Handwerker, Joanne Macen, Grant McFadden	76
18	Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases 1997 ·Journal of Medicinal Chemistry ·Juswinder Singh, Ellen M. Dobrusin, David W. Fry, (unknown), Adrian Whitty, Dennis J. McNamara	89
19	A Direct Binding Assay for the Vascular Cell Adhesion Molecule-1 (VCAM1) Interaction with α4 Integrins 1995 ·Cell adhesion and communications/Cell adhesion and communication/Cell adhesion & communication ·Roy R. Lobb, (unknown), R. Blake Pepinsky, Linda C. Burkly, Diane R. Leone, Adrian Whitty	34
20	Role of Binding Energy with Coenzyme A in Catalysis by 3-Oxoacid Coenzyme A Transferase 1995 ·Biochemistry ·Adrian Whitty, Carol A. Fierke, William P. Jencks	41

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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