Shigeru Kakuta

9.0k total citations · 3 hit papers
74 papers, 6.4k citations indexed

About

Shigeru Kakuta is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Shigeru Kakuta has authored 74 papers receiving a total of 6.4k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Immunology, 28 papers in Molecular Biology and 8 papers in Epidemiology. Recurrent topics in Shigeru Kakuta's work include Immune Cell Function and Interaction (14 papers), T-cell and B-cell Immunology (10 papers) and Immune Response and Inflammation (8 papers). Shigeru Kakuta is often cited by papers focused on Immune Cell Function and Interaction (14 papers), T-cell and B-cell Immunology (10 papers) and Immune Response and Inflammation (8 papers). Shigeru Kakuta collaborates with scholars based in Japan, United States and Philippines. Shigeru Kakuta's co-authors include Yoichiro Iwakura, Katsuko Sudo, Harumichi Ishigame, Susumu Nakae, Aya Nambu, Yutaka Komiyama, Taizo Matsuki, Hideo Yagita∥, Kazuyoshi Takeda and Yoshihiro Hayakawa and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Shigeru Kakuta

70 papers receiving 6.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

2006 1.3k citations Yutaka Komiyama, Susumu Nakae et al. The Journal of Immunology profile →
Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

2009 813 citations Harumichi Ishigame, Shigeru Kakuta et al. Immunity profile →
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

2001 595 citations Shigeru Kakuta, Yoichiro Iwakura et al. profile →

Peers

Countries citing papers authored by Shigeru Kakuta

Since Specialization

Citations

This map shows the geographic impact of Shigeru Kakuta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shigeru Kakuta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shigeru Kakuta more than expected).

Fields of papers citing papers by Shigeru Kakuta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shigeru Kakuta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shigeru Kakuta. The network helps show where Shigeru Kakuta may publish in the future.

Co-authorship network of co-authors of Shigeru Kakuta

This figure shows the co-authorship network connecting the top 25 collaborators of Shigeru Kakuta. A scholar is included among the top collaborators of Shigeru Kakuta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shigeru Kakuta. Shigeru Kakuta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Dectin-1 facilitates lung fungal-mediated pulmonary fibrosis 2025 ·Immunity ·Ding Qiu, Shuishen Zhang, Chanyan Huang, Xinying Wang, Jianping Deng, Haiyang Sun, Bingbing Feng, Ying Tan, (unknown), (unknown), Xiaoqi Ye, Chao Cheng, Shigeru Kakuta, Yoshiyuki Adachi, Yoichiro Iwakura, Shuai Wang, Shaowei Dong, Ce Tang	0
2	Establishment of the improved colonization of Escherichia coli laboratory strain in the intestine mediated by single gene deletion 2024 ·Biochemical and Biophysical Research Communications ·(unknown), (unknown), Tsuyoshi Tachibana, Yu Tanaka, (unknown), (unknown), (unknown), (unknown), (unknown), Yoh‐ichi Tagawa, Tomohisa Kuzuyama, Shigeru Kakuta, Tetsuhiro Ogawa	0
3	Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes 2023 ·Methods in molecular biology ·Masahiro Sato, Ayaka Nakamura, (unknown), Takashi Matsuwaki, Hiromi Miura, Channabasavaiah B. Gurumurthy, Shigeru Kakuta, Masato Ohtsuka	3
4	Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma 2019 ·Scientific Reports ·(unknown), Shigeru Kakuta, Yulan Tang, James Chambers, Kazuyuki Uchida, Maria Amelita C. Estacio, Cleofas R. Cervancia, (unknown), Hideki Ushio, Jun Nakayama, Hiroyuki Nakayama, Shigeru Kyuwa	27
5	Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota 2018 ·Nature Immunology ·Ce Tang, Shigeru Kakuta, Kenji Shimizu, Motohiko Kadoki, Tomonori Kamiya, Tomoyuki Shimazu, Sachiko Kubo, Shinobu Saijo, Harumichi Ishigame, Susumu Nakae, Yoichiro Iwakura	132
6	Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis 2017 ·Journal of Clinical Investigation ·Naoto Koyanagi, Takahiko Imai, Keiko Shindo, Ayuko Sato, Wataru Fujii, Takeshi Ichinohe, Naoki Takemura, Shigeru Kakuta, Satoshi Uematsu, Hiroshi Kiyono, Yuhei Maruzuru, Jun Arii, Akihisa Kato, Yasushi Kawaguchi	36
7	Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo 2016 ·Frontiers in Immunology ·Takahiro Adachi, Shigeru Kakuta, Yoshiko Aihara, Tomonori Kamiya, Yohei Watanabe, Naomi Osakabe, (unknown), Atsushi Miyawaki, Soichiro Yoshikawa, Takako Usami, Hajime Karasuyama, Hiromi Kimoto‐Nira, Kazuhiro Hirayama, Noriko M. Tsuji	22
8	IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells 2015 ·Nature Communications ·Aoi Akitsu, Harumichi Ishigame, Shigeru Kakuta, Soo-Hyun Chung, Satoshi Ikeda, Kenji Shimizu, Sachiko Kubo, Yang Liu, Masayuki Umemura, Goro Matsuzaki, Yasunobu Yoshikai, Shinobu Saijo, Yoichiro Iwakura	97
9	Gene Targeting Study Reveals Unexpected Expression of Brain-expressed X-linked 2 in Endocrine and Tissue Stem/Progenitor Cells in Mice 2014 ·Journal of Biological Chemistry ·Keiichi Ito, Satoshi Yamazaki, Ryō Yamamoto, Yoko Tajima, Ayaka Yanagida, Toshihiro Kobayashi, Megumi Kato‐Itoh, Shigeru Kakuta, Yoichiro Iwakura, Hiromitsu Nakauchi, Akihide Kamiya	19
10	Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages 2014 ·PLoS ONE ·Tomoyuki Oshio, Rei Kawashima, Yuki I. Kawamura, Teruki Hagiwara, Noriko Mizutani, Toshihiko Okada, Takeshi Otsubo, Kyoko Inagaki‐Ohara, Akihiro Matsukawa, Tatsuya Haga, Shigeru Kakuta, Yoichiro Iwakura, Seijiro Hosokawa, Taeko Dohi	29
11	Generation of a Mouse Model with Down-Regulated U50 snoRNA (SNORD50) Expression and Its Organ-Specific Phenotypic Modulation 2013 ·PLoS ONE ·(unknown), (unknown), (unknown), Masataka Asagiri, Shigeru Kakuta, Yuji Taya, Yoshihito Shimazu, Kaori Sato, (unknown), Sachiko Kubo, Yoichiro Iwakura, Yoshikazu Nakamura, Shigeo Mori, Takaaki Aoba	13
12	C-type Lectin MCL Is an FcRγ-Coupled Receptor that Mediates the Adjuvanticity of Mycobacterial Cord Factor 2013 ·Immunity ·Yasunobu Miyake, Kenji Toyonaga, Daiki Mori, Shigeru Kakuta, Yoshihiko Hoshino, Akiko Oyamada, Hisakata Yamada, Ken-ichiro Ono, Mikita Suyama, Yoichiro Iwakura, Yasunobu Yoshikai, Sho Yamasaki	183
13	A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens 2011 ·Cell Host & Microbe ·Michinaga Ogawa, Yuko Yoshikawa, T. Kobayashi, Hitomi Mimuro, (unknown), Kotaro Kiga, (unknown), Hiroshi Ashida, Mitsutaka Yoshida, Shigeru Kakuta, Tomohiro Koyama, Yoshiyuki Goto, Takahiro Nagatake, Shinya Nagai, Hiroshi Kiyono, Magdalena Kawalec, Jean‐Marc Reichhart, Chihiro Sasakawa	122
14	Upregulation of Polymeric Immunoglobulin Receptor Expression by the Heat‐Inactivated Potential Probiotic Bifidobacterium bifidum OLB6378 in a Mouse Intestinal Explant Model 2011 ·Scandinavian Journal of Immunology ·Yoshitaka Nakamura, (unknown), T. Iwamoto, Kaoru Yamada, Masatake Asano, Shigeru Kakuta, Yoichiro Iwakura, Mamoru Totsuka	27
15	Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice 2010 ·Neuroscience Research ·Shinji Hadano, Yasuhiro Yoshii, Asako Otomo, Ryota Kunita, Kyoko Suzuki-Utsunomiya, Lei Pan, Shigeru Kakuta, Yasuo Iwasaki, Yoichiro Iwakura, Joh-E Ikeda	12
16	Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses breakdown → 2009 ·Immunity ·Harumichi Ishigame, Shigeru Kakuta, Takeshi Nagai, Motohiko Kadoki, Aya Nambu, Yutaka Komiyama, Noriyuki Fujikado, (unknown), Aoi Akitsu, Hayato Kotaki, Katsuko Sudo, Susumu Nakae, Chihiro Sasakawa, Yoichiro Iwakura	813
17	IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis breakdown → 2006 ·The Journal of Immunology ·Yutaka Komiyama, Susumu Nakae, Taizo Matsuki, Aya Nambu, Harumichi Ishigame, Shigeru Kakuta, Katsuko Sudo, Yoichiro Iwakura	1279
18	Oral exposure to cadmium chloride triggers an acute inflammatory response in the intestines of mice, initiated by the over-expression of tissue macrophage inflammatory protein-2 mRNA 2006 ·Toxicology Letters ·Zhaohui Zhao, (unknown), Hideo Satsu, Shigeru Kakuta, Makoto Shimizu	50
19	Interleukin (IL)-6, But Not IL-1, Induction in the Brain Downstream of Cyclooxygenase-2 Is Essential for the Induction of Febrile Response against Peripheral IL-1α 2004 ·Endocrinology ·(unknown), Dai Chida, (unknown), Masahide Asano, Aya Nambu, Shigeru Kakuta, Yoichiro Iwakura	30
20	Genomic Structure of the Mouse 2',5'-Oligoadenylate Synthetase Gene Family 2002 ·Journal of Interferon & Cytokine Research ·Shigeru Kakuta, Shinwa Shibata, Yoichiro Iwakura	87

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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