Hollis D. Showalter

3.9k citations

89 papers · 3.1k indexed · 1 hit paper · h-index 31

Physiology top 0.5%
Organic Chemistry top 2%
- Synthesis and Characterization of Heterocyclic Compounds 6
- Synthesis and biological activity 5
Molecular Biology top 5%
- Cancer therapeutics and mechanisms 14
- Ubiquitin and proteasome pathways 11
- Biochemical and Molecular Research 8
- Chemical Synthesis and Analysis 7
Toxicology top 2%
Sensory Systems top 5%
Infectious Diseases
- Tuberculosis Research and Epidemiology 8
- HIV/AIDS drug development and treatment 6

Co-authors: Paul D. Kirchhoff George A. Garcia Terri L. Boehm Roderick J. Sorenson Alan J. Kraker Nouri Neamati Nicholas J. Donato Tomasz Cierpicki
Cited by: Physiology Organic Chemistry Molecular Biology
Journals: Journal of the American Chemical Society (1 paper)Nucleic Acids Research (1 paper)Nature Communications (1 paper)
Partner nations: United States United Kingdom New Zealand

In The Last Decade

Hollis D. Showalter

88 papers receiving 3.0k citations

Hit Papers

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Peers

Countries citing papers authored by Hollis D. Showalter

Since Specialization

Citations

This map shows the geographic impact of Hollis D. Showalter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hollis D. Showalter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hollis D. Showalter more than expected).

Fields of papers citing papers by Hollis D. Showalter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hollis D. Showalter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hollis D. Showalter. The network helps show where Hollis D. Showalter may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hollis D. Showalter, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hollis D. Showalter Line = papers co-authored together Hollis D. Showalter links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A concise synthesis of 3-substituted-7-amino-6-carboxyl-8-azachromones Tetrahedron Letters ·Xinmin Gan,Hollis D. Showalter	2019	2
2	Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses Scientific Reports ·Marie‐Ève Charbonneau,Karla D. Passalacqua,Susan E. Hagen,Hollis D. Showalter,Christiane E. Wobus,Mary O’Riordan	2019	20
3	Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR Structure ·Alex J. McDonald,Deborah R. Leon,Kathleen Markham,Bei Wu,Christian F. Heckendorf,Kevin M. Schilling,Hollis D. Showalter,Philip Andrews,Mark E. McComb,M. Jake Pushie,Catherine E. Costello,Glenn L. Millhauser,David A. Harris	2019	27
4	Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer Pharmacology & Therapeutics ·Joseph T. Madak,Armand Bankhead,Christine R. Cuthbertson,Hollis D. Showalter,Nouri Neamati	2018	147
5	Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects Neuropsychopharmacology ·Colleen Carpenter,Alexander G. Zestos,Rachel D. Altshuler,Roderick J. Sorenson,Bipasha Guptaroy,Hollis D. Showalter,Robert T. Kennedy,Emily M. Jutkiewicz,Margaret E. Gnegy	2017	23
6	Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C Bioorganic & Medicinal Chemistry ·Colleen Carpenter,Roderick J. Sorenson,Yafei Jin,Szymon Kłossowski,Tomasz Cierpicki,Margaret E. Gnegy,Hollis D. Showalter	2016	12
7	Novel Carboxaldehyde Mediated Synthetic Pathway for 5′-Amino Adenosine Analogues Nucleosides Nucleotides & Nucleic Acids ·Garrett S. Gibbons,Hollis D. Showalter,Zaneta Nikolovska‐Coleska	2015	1
8	Synthesis and structure–activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors Bioorganic & Medicinal Chemistry Letters ·Paul M. Titchenell,Hollis D. Showalter,Jean‐François Pons,Alistair J. Barber,Yafei Jin,David A. Antonetti	2013	11
9	Structure-Based Design of Novel Benzoxazinorifamycins with Potent Binding Affinity to Wild-Type and Rifampin-Resistant Mutant Mycobacterium tuberculosis RNA Polymerases Journal of Medicinal Chemistry ·Sumandeep K. Gill,Hao Xu,Paul D. Kirchhoff,Tomasz Cierpicki,Anjanette J. Turbiak,Baojie Wan,Nan Zhang,Kuan-wei Peng,Scott G. Franzblau,George A. Garcia,Hollis D. Showalter	2012	24
10	Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response PLoS Pathogens ·Jeffrey W. Perry,Mohammad Ahmed,Kyeong‐Ok Chang,Nicholas J. Donato,Hollis D. Showalter,Christiane E. Wobus	2012	70
11	Synthesis and structure–activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin Bioorganic & Medicinal Chemistry Letters ·Yafei Jin,Sumandeep K. Gill,Paul D. Kirchhoff,Baojie Wan,Scott G. Franzblau,George A. Garcia,Hollis D. Showalter	2011	12
12	Use of Enterally Delivered Angiotensin II Type Ia Receptor Antagonists to Reduce the Severity of Colitis Digestive Diseases and Sciences ·Manabu Okawada,Hiroyuki Koga,Scott D. Larsen,Hollis D. Showalter,Anjanette J. Turbiak,Xiaohong Jin,Peter C. Lucas,Elke Lipka,John Hillfinger,Jae Seung Kim,Daniel H. Teitelbaum	2011	21
13	A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination Cellular Signalling ·Vaibhav Kapuria,Alexander Levitzki,William G. Bornmann,David S. Maxwell,Waldemar Priebe,Roderick J. Sorenson,Hollis D. Showalter,Moshe Talpaz,Nicholas J. Donato	2011	39
14	A novel synthesis of 3-(substituted)pyrimido[4,5-c]pyridazine-5,7(1H,6H)-diones Tetrahedron Letters ·Anjanette J. Turbiak,Jeff W. Kampf,Hollis D. Showalter	2010	15
15	Rifamycins – Obstacles and opportunities Tuberculosis ·Paul A. Aristoff,George A. Garcia,Paul D. Kirchhoff,Hollis D. Showalter	2010	140
16	Enediol mimics as inhibitors of the d-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis Bioorganic & Medicinal Chemistry Letters ·Alejandra Yep,Roderick J. Sorenson,Michael R. Wilson,Hollis D. Showalter,Scott D. Larsen,Paul R. Keller,Ronald W. Woodard	2010	14
17	A novel synthesis of N1-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones Tetrahedron Letters ·Anjanette J. Turbiak,Hollis D. Showalter	2009	4
18	Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones Bioorganic & Medicinal Chemistry Letters ·Kim Hutchings,Tuan P. Tran,Edmund L. Ellsworth,Brian M. Watson,Joseph P. Sanchez,Hollis D. Showalter,Michael A. Stier,Martin A. Shapiro,E. Themis Joannides,Michael D. Huband,Dai Q. Nguyen,Samarendra N. Maiti,Tingsheng Li,Jyoti Tailor,George Thomas,Chan Ha,Rajeshwar Singh	2008	17
19	A roadmap for drug discovery and its translation to small molecule agents in clinical development for tuberculosis treatment Tuberculosis ·Hollis D. Showalter,William A. Denny	2008	54
20	Small molecule inhibitors of the platelet-derived growth factor receptor, the fibroblast growth factor receptor, and Src family tyrosine kinases Pharmacology & Therapeutics ·Hollis D. Showalter,Alan J. Kraker	1997	30

About Hollis D. Showalter

Hollis D. Showalter is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases, having authored 89 papers that have together received 3.1k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (14 papers), Ubiquitin and proteasome pathways (11 papers), Biochemical and Molecular Research (8 papers), Tuberculosis Research and Epidemiology (8 papers), Chemical Synthesis and Analysis (7 papers), Synthesis and Characterization of Heterocyclic Compounds (6 papers), HIV/AIDS drug development and treatment (6 papers) and Synthesis and biological activity (5 papers). The work is most often cited by research in Physiology (337 citations), Organic Chemistry (853 citations) and Molecular Biology (1.8k citations). Hollis D. Showalter has collaborated with scholars based in United States, United Kingdom and New Zealand. Frequent co-authors include Paul D. Kirchhoff, George A. Garcia, Terri L. Boehm, Roderick J. Sorenson, Alan J. Kraker, Nouri Neamati, Nicholas J. Donato, Tomasz Cierpicki, Zepeng Yao and Haoxing Xu. Their work appears in journals such as Journal of the American Chemical Society, Nucleic Acids Research and Nature Communications.

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