Frank J. Dekker

6.7k citations

127 papers · 4.8k indexed · 1 hit paper · h-index 38

Molecular Biology top 2%
Organic Chemistry top 2%
Oncology top 5%
Immunology top 5%
Cellular and Molecular Neuroscience top 5%

Co-authors: Hidde J. Haisma Martijn R. H. Zwinderman Harm Maarsingh Rosalina Wisastra Hannah Wapenaar Massimo Ghizzoni Herbert Waldmann Niek G.J. Leus
Topics: Histone Deacetylase Inhibitors Research (33 papers)Protein Degradation and Inhibitors (20 papers)Peptidase Inhibition and Analysis (18 papers)
Cited by: Molecular Biology Toxicology Organic Chemistry
Journals: Nucleic Acids Research Journal of Biological Chemistry Angewandte Chemie International Edition
Partner nations: Netherlands Germany Italy

In The Last Decade

Frank J. Dekker

126 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rational Design in Photopharmacology with Molecular Photoswitches

2023 133 citations Frank J. Dekker et al. Angewandte Chemie International Edition profile →

Peers

Countries citing papers authored by Frank J. Dekker

Since Specialization

Citations

This map shows the geographic impact of Frank J. Dekker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank J. Dekker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank J. Dekker more than expected).

Fields of papers citing papers by Frank J. Dekker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank J. Dekker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank J. Dekker. The network helps show where Frank J. Dekker may publish in the future.

Co-authorship network of co-authors of Frank J. Dekker

This figure shows the co-authorship network connecting the top 25 collaborators of Frank J. Dekker. A scholar is included among the top collaborators of Frank J. Dekker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank J. Dekker. Frank J. Dekker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Small Molecule MIF Modulation Enhances Ferroptosis by Impairing DNA Repair Mechanisms 2024 ·Advanced Science ·Deng Chen,Chunlong Zhao,Jianqiu Zhang,(unknown),(unknown),(unknown),(unknown),Zhangping Xiao,(unknown),Andrew J. Griffith,(unknown),(unknown),Robert P. Coppes,Amalia M. Dolga,Hidde J. Haisma,Frank J. Dekker	7
2	Protocol of the Double‐Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins 2023 ·Current Protocols ·Petra E. van der Wouden,Martijn R. H. Zwinderman,Deng Chen,Michela Borghesan,Frank J. Dekker	0
3	Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos 2023 ·Journal of Medicinal Chemistry ·Deng Chen,(unknown),(unknown),(unknown),Maxim Gureev,(unknown),(unknown),Zhangping Xiao,Petra E. van der Wouden,Robbert H. Cool,Gerrit J. Poelarends,Frank J. Dekker	6
4	Histone Deacetylase 3‐Directed PROTACs Have Anti‐inflammatory Potential by Blocking Polarization of M0‐like into M1‐like Macrophages 2023 ·Angewandte Chemie International Edition ·(unknown),Shipeng Chen,Deng Chen,(unknown),Jianqiu Zhang,Petra E. van der Wouden,Toos Daemen,Frank J. Dekker	14
5	Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury 2022 ·Cellular and Molecular Life Sciences ·Shanshan Song,Zhangping Xiao,Frank J. Dekker,Gerrit J. Poelarends,Barbro N. Melgert	46
6	Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells 2021 ·Angewandte Chemie ·Zhangping Xiao,Shanshan Song,Deng Chen,Ronald van Merkerk,Petra E. van der Wouden,Robbert H. Cool,Wim J. Quax,Gerrit J. Poelarends,Barbro N. Melgert,Frank J. Dekker	3
7	Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells 2021 ·Angewandte Chemie International Edition ·Zhangping Xiao,Shanshan Song,Deng Chen,Ronald van Merkerk,Petra E. van der Wouden,Robbert H. Cool,Wim J. Quax,Gerrit J. Poelarends,Barbro N. Melgert,Frank J. Dekker	37
8	HDAC/MIF dual inhibitor inhibits NSCLC cell survival and proliferation by blocking the AKT pathway 2021 ·Bioorganic Chemistry ·Fangyuan Cao,Zhangping Xiao,Siwei Chen,Chunlong Zhao,Deng Chen,Hidde J. Haisma,Frank J. Dekker	18
9	Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC) 2020 ·European Journal of Medicinal Chemistry ·Fangyuan Cao,(unknown),Deng Chen,Martijn R. H. Zwinderman,Petra E. van der Wouden,Frank J. Dekker	63
10	Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing 2019 ·Nucleic Acids Research ·Bin Liu,Siwei Chen,(unknown),Deng Chen,Fangyuan Cao,Martijn R. H. Zwinderman,Dominik Kiemel,(unknown),Frank J. Dekker,Hidde J. Haisma	281
11	Small Multitarget Molecules Incorporating the Enone Moiety 2019 ·Molecules ·(unknown),Nikolaos Eleftheriadis,Frank J. Dekker,(unknown),Konstantinos Avgoustakis,Marina Sagnou,Barbara Mavroidi,Maria Pelecanou,Dimitra Hadjipavlou‐Litina	18
12	Small-molecule inhibitors of macrophage migration inhibitory factor (MIF) as an emerging class of therapeutics for immune disorders 2018 ·Drug Discovery Today ·(unknown),(unknown),Robbert H. Cool,Barbro N. Melgert,Gerrit J. Poelarends,Frank J. Dekker	48
13	Photoactivation provides a mechanistic explanation for pan-assay interference behaviour of 2-aminopyrroles in lipoxygenase inhibition 2017 ·European Journal of Medicinal Chemistry ·Hao Guo,Nikolaos Eleftheriadis,Nataliya Rohr‐Udilova,Alexander Dömlingꝉ,Frank J. Dekker	11
14	The degradation of nucleotide triphosphates extracted under boiling ethanol conditions is prevented by the yeast cellular matrix 2016 ·Metabolomics ·(unknown),David J. Siegel,(unknown),Hjalmar P. Permentier,Dirk‐Jan Reijngoud,Frank J. Dekker,Rainer Bischoff	12
15	Enzyme kinetics and inhibition of histone acetyltransferase KAT8 2015 ·European Journal of Medicinal Chemistry ·Hannah Wapenaar,Petra E. van der Wouden,Matthew R. Groves,Dante Rotili,Antonello Mai,Frank J. Dekker	26
16	Delivery of epidrugs 2014 ·Drug Discovery Today ·(unknown),Frank J. Dekker,Nadine Martinet,Philìppe Bertrand	19
17	A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging 2014 ·Bioorganic & Medicinal Chemistry ·(unknown),Riccardo Castelli,Adriaan W. Tuin,Herman S. Overkleeft,Rosalina Wisastra,Frank J. Dekker,(unknown),Rainer Bischoff,Aren van Waarde,Rudi Dierckx,Philip H. Elsinga	14
18	Isothiazolones; thiol-reactive inhibitors of cysteine protease cathepsin B and histone acetyltransferase PCAF 2011 ·Organic & Biomolecular Chemistry ·Rosalina Wisastra,Massimo Ghizzoni,Harm Maarsingh,Adriaan J. Minnaard,Hidde J. Haisma,Frank J. Dekker	18
19	Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling 2010 ·Bioorganic & Medicinal Chemistry ·Frank J. Dekker,Christian Hedberg	19
20	Role of solution conformation and flexibility of short peptide ligands that bind to the p56lck SH2 domain 2003 ·Bioorganic & Medicinal Chemistry ·Frank J. Dekker,Nico J. de Mol,Patrick Bultinck,Johan Kemmink,(unknown),Rob M. J. Liskamp	13

About Frank J. Dekker

Frank J. Dekker is a scholar working on Toxicology, Molecular Biology and Aging, having authored 127 papers that have together received 4.8k indexed citations. Recurring topics across this work include Histone Deacetylase Inhibitors Research (33 papers), Protein Degradation and Inhibitors (20 papers) and Peptidase Inhibition and Analysis (18 papers). The work is most often cited by research in Molecular Biology (3.2k citations), Toxicology (103 citations) and Organic Chemistry (804 citations). Frank J. Dekker has collaborated with scholars based in Netherlands, Germany and Italy. Frequent co-authors include Hidde J. Haisma, Martijn R. H. Zwinderman, Harm Maarsingh, Rosalina Wisastra, Hannah Wapenaar, Massimo Ghizzoni, Herbert Waldmann, Niek G.J. Leus, Martina Schmidt and Deng Chen. Their work appears in journals such as Nucleic Acids Research, Journal of Biological Chemistry and Angewandte Chemie International Edition.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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