Steven W. Muchmore

5.8k citations

49 papers · 4.6k indexed · 2 hit papers · h-index 26

Molecular Biology top 2%
Computational Theory and Mathematics top 0.5%
Immunology top 5%
Oncology top 5%
Genetics top 5%

Co-authors: Scott P. Brown Stephen W. Fesik Craig B. Thompson Heng Liang John E. Harlan Shi‐Chung Ng Robert Meadows Michael Sattler
Topics: Computational Drug Discovery Methods (11 papers)Protein Structure and Dynamics (10 papers)Enzyme Structure and Function (7 papers)
Cited by: Molecular Biology Computational Theory and Mathematics Immunology
Journals: Nature Science Journal of Biological Chemistry
Partner nations: United States United Kingdom Canada

In The Last Decade

Steven W. Muchmore

49 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1996 1.2k citations Steven W. Muchmore, John E. Harlan et al. profile →
Bcl-xL forms an ion channel in synthetic lipid membranes

1997 682 citations Steven W. Muchmore et al. profile →

Peers

Countries citing papers authored by Steven W. Muchmore

Since Specialization

Citations

This map shows the geographic impact of Steven W. Muchmore's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven W. Muchmore with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven W. Muchmore more than expected).

Fields of papers citing papers by Steven W. Muchmore

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven W. Muchmore. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven W. Muchmore. The network helps show where Steven W. Muchmore may publish in the future.

Co-authorship network of co-authors of Steven W. Muchmore

This figure shows the co-authorship network connecting the top 25 collaborators of Steven W. Muchmore. A scholar is included among the top collaborators of Steven W. Muchmore based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven W. Muchmore. Steven W. Muchmore is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	POSIT: Flexible Shape-Guided Docking For Pose Prediction 2015 ·Journal of Chemical Information and Modeling ·Brian Kelley,Scott P. Brown,Gregory L. Warren,Steven W. Muchmore	108
2	ALOHA: a novel probability fusion approach for scoring multi-parameter drug-likeness during the lead optimization stage of drug discovery 2013 ·Journal of Computer-Aided Molecular Design ·Derek A. Debe,(unknown),Robert J. Gregg,James T. Metz,Rishi R. Gupta,Steven W. Muchmore	7
3	Frozen out: molecular modeling in the age of cryocrystallography 2011 ·Journal of Computer-Aided Molecular Design ·Yvonne C. Martin,Steven W. Muchmore	2
4	Molecular Shape and Medicinal Chemistry: A Perspective 2010 ·Journal of Medicinal Chemistry ·Anthony Nicholls,Georgia B. McGaughey,Robert P. Sheridan,Andrew C. Good,Gregory L. Warren,Magali Mathieu,Steven W. Muchmore,Scott P. Brown,Jennifer Grant,(unknown),Neysa Nevins,Ajay N. Jain,Brian Kelley	254
5	Healthy skepticism: assessing realistic model performance 2009 ·Drug Discovery Today ·Scott P. Brown,Steven W. Muchmore,Philip J. Hajduk	97
6	Application of Belief Theory to Similarity Data Fusion for Use in Analog Searching and Lead Hopping 2008 ·Journal of Chemical Information and Modeling ·Steven W. Muchmore,Derek A. Debe,James T. Metz,Scott P. Brown,Yvonne C. Martin,Philip J. Hajduk	121
7	4-Amino-5-aryl-6-arylethynylpyrimidines: Structure–activity relationships of non-nucleoside adenosine kinase inhibitors 2006 ·Bioorganic & Medicinal Chemistry ·Mark A. Matulenko,Ernest S. Paight,Robin R. Frey,Arthur Gomtsyan,Stanley DiDomenico,(unknown),(unknown),Andrew O. Stewart,Haixia Yu,Kathy L. Kohlhaas,Karen M. Alexander,Steve McGaraughty,Joseph P. Mikusa,Kennan C. Marsh,Steven W. Muchmore,(unknown),Elizabeth A. Kowaluk,Michael F. Jarvis,Shripad S. Bhagwat	25
8	Crystal Structures of Human Adenosine Kinase Inhibitor Complexes Reveal Two Distinct Binding Modes 2006 ·Journal of Medicinal Chemistry ·Steven W. Muchmore,Richard A. Smith,Andrew O. Stewart,Marlon Cowart,Arthur Gomtsyan,Mark A. Matulenko,Haixia Yu,Jean M. Severin,Shripad S. Bhagwat,Chih‐Hung Lee,Elizabeth A. Kowaluk,Michael F. Jarvis,(unknown)	23
9	The Use of Three‐Dimensional Shape and Electrostatic Similarity Searching in the Identification of a Melanin‐Concentrating Hormone Receptor 1 Antagonist 2006 ·Chemical Biology & Drug Design ·Steven W. Muchmore,Andrew J. Souers,Irini Akritopoulou‐Zanze	62
10	Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors 2004 ·Bioorganic & Medicinal Chemistry Letters ·Qun Li,Akiyo Claiborne,Tongmei Li,Lisa Hasvold,Vincent S. Stoll,Steven W. Muchmore,Clarissa G. Jakob,(unknown),Jerry D. Cohen,Charles W. Hutchins,David J. Frost,Saul H. Rosenberg,Hing L. Sham	21
11	The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain 2003 ·Journal of Biological Chemistry ·Björn Kauppi,Clarissa G. Jakob,Mathias Färnegårdh,Jie Yang,Harri Ahola,M. Alarcon,(unknown),Owe Engström,John E. Harlan,Steven W. Muchmore,(unknown),(unknown),Lars Öhman,Jonathan Greer,Jan-Åke Gustafsson,Jan Carlstedt‐Duke,Mats Carlquist	277
12	Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyltransferase 2003 ·Bioorganic & Medicinal Chemistry Letters ·Michael L. Curtin,Alan S. Florjancic,Jerome Cohen,Wen‐Zhen Gu,David J. Frost,Steven W. Muchmore,Hing L. Sham	12
13	Automated Crystal Mounting and Data Collection for Protein Crystallography 2000 ·Structure ·Steven W. Muchmore,Jeffrey L. Olson,Ronald N. Jones,(unknown),Michael L. Blum,Jonathan Greer,(unknown),(unknown),V. Nienaber	54
14	Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin 2000 ·Molecular Cell ·Steven W. Muchmore,Jun Chen,Clarissa G. Jakob,Dorothy Zakula,Edmund D. Matayoshi,Wei Wu,Haichao Zhang,Fengzhi Li,Shi‐Chung Ng,Dario C. Altieri	104
15	Experiences with CCD detectors on a home X-ray source 1999 ·Acta Crystallographica Section D Biological Crystallography ·Steven W. Muchmore	9
16	Structure of Secreted Aspartic Proteinases from Candida 1998 ·Advances in experimental medicine and biology ·Cele Abad‐Zapatero,Robert C. Goldman,Steven W. Muchmore,Charles W. Hutchins,Tetsuro Oie,Kent D. Stewart,(unknown),J.F. Cutfield,Stephen I. Foundling,Thomas L. Ray	13
17	Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: Implications for the design of antifungal agents 1996 ·Protein Science ·Cele Abad‐Zapatero,Robert C. Goldman,Steven W. Muchmore,Charles W. Hutchins,Kent D. Stewart,Jorge Navaza,Candia D. Payne,Thomas L. Ray	92
18	Crystallization of the NAD-dependent malic enzyme from the parasitic nematode Ascaris suum 1992 ·Journal of Molecular Biology ·Luke Clancy,G S Rao,B.C. Finzel,Steven W. Muchmore,Debra R. Holland,Keith David Watenpaugh,Harini Krishnamurthy,Robert M. Sweet,Paul Cook,Ben G. Harris,(unknown)	10
19	Crystal structure of recombinant human interleukin-1β at 2·0 Å resolution 1989 ·Journal of Molecular Biology ·B.C. Finzel,L.L. Clancy,Debra R. Holland,Steven W. Muchmore,Keith David Watenpaugh,Howard Einspahr	158
20	Crystallization of purified recombinant human interleukin‐1β 1988 ·Proteins Structure Function and Bioinformatics ·(unknown),(unknown),(unknown),Anthony W. Yem,Martin R. Deibel,Daniel E. Tracey,(unknown),(unknown),Nicole Y. Thériault,Peter K.W. Harris,Ilene M. Reardon,Heidi A. Zürcher-Neely,Robert L. Heinrikson,L.L. Clancy,Steven W. Muchmore,Keith David Watenpaugh,Howard Einspahr	41

About Steven W. Muchmore

Steven W. Muchmore is a scholar working on Computational Theory and Mathematics, Molecular Biology and Spectroscopy, having authored 49 papers that have together received 4.6k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (11 papers), Protein Structure and Dynamics (10 papers) and Enzyme Structure and Function (7 papers). The work is most often cited by research in Molecular Biology (3.3k citations), Computational Theory and Mathematics (761 citations) and Immunology (514 citations). Steven W. Muchmore has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Scott P. Brown, Stephen W. Fesik, Craig B. Thompson, Heng Liang, John E. Harlan, Shi‐Chung Ng, Robert Meadows, Michael Sattler, David G. Nettesheim and Brian S. Chang. Their work appears in journals such as Nature, Science and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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