John K. Walker

1.9k citations

49 papers · 1.1k indexed · h-index 20

Impact in

Molecular Medicine top 2%
- Antibiotic Resistance in Bacteria
Cancer Research
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism

Papers in ⓘ

Molecular Biology 28
- Phenothiazines and Benzothiazines Synthesis and Activities 7
- Receptor Mechanisms and Signaling 5
- Melanoma and MAPK Pathways 4
Organic Chemistry 12
- Synthesis and biological activity 5

Co-authors: Helen I. Zgurskaya (14 shared papers)Jerry M. Parks (8 shared papers)Valentin V. Rybenkov (8 shared papers)Thomas P. Burris (8 shared papers)Arindam Chatterjee (6 shared papers)Bahaa Elgendy (4 shared papers)Melissa Kazantzis (2 shared papers)David Wolloscheck (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)ACS Infectious Diseases (6 papers)The Journal of Immunology (2 papers)ACS Chemical Biology (2 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)
Partner nations: United States Italy United Kingdom

In The Last Decade

John K. Walker

48 papers receiving 1.0k citations

Peers

Countries citing papers authored by John K. Walker

Since Specialization

Citations

This map shows the geographic impact of John K. Walker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John K. Walker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John K. Walker more than expected).

Fields of papers citing papers by John K. Walker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John K. Walker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John K. Walker. The network helps show where John K. Walker may publish in the future.

Co-authors

The 25 scholars most cited alongside John K. Walker, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John K. Walker Line = papers co-authored together John K. Walker links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 49 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis Cancer Cell ·Colin A. Flaveny, Kristine Griffett, Bahaa Elgendy, Melissa Kazantzis, Monideepa Sengupta, Antonio L. Amelio, Arindam Chatterjee, John K. Walker, Laura A. Solt, Theodore M. Kamenecka, Thomas P. Burris	2015	160
2	Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain Proceedings of the National Academy of Sciences ·Zhoumou Chen, Timothy M. Doyle, Livio Luongo, Tally M. Largent‐Milnes, Luigino Antonio Giancotti, Grant R. Kolar, Silvia Squillace, Serena Boccella, John K. Walker, Alexander L. Pendleton, Sarah Spiegel, William L. Neumann, Todd W. Vanderah, Daniela Salvemini	2019	92
3	Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump ACS Infectious Diseases ·Narges Abdali, Jerry M. Parks, Keith M. Haynes, Julie L. Chaney, Adam T. Green, David Wolloscheck, John K. Walker, Valentin V. Rybenkov, Jérôme Baudry, Jeremy C. Smith, Helen I. Zgurskaya	2016	78
4	Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa ACS Infectious Diseases ·Connor J. Cooper, Ganesh Krishnamoorthy, David Wolloscheck, John K. Walker, Valentin V. Rybenkov, Jerry M. Parks, Helen I. Zgurskaya	2018	60
5	Lymphocytotoxic antibodies in multiple sclerosis Clinical Immunology and Immunopathology ·Alan L. Schocket, Howard L. Weiner, John K. Walker, Kenneth McIntosh, Peter F. Köhler	1977	47
6	Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804 Biochemistry ·Xing Li, H.-S. Shieh, Shaun R. Selness, Rajesh Devraj, John K. Walker, Balekudru Devadas, Heidi R. Hope, Robert P. Compton, John F. Schindler, Jeffrey L. Hirsch, Alan G. Benson, Ravi G. Kurumbail, Roderick A. Stegeman, Jennifer M. Williams, Richard M. Broadus, Zara Walden, Joseph B. Monahan	2009	43
7	Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli Journal of Medicinal Chemistry ·Keith M. Haynes, Narges Abdali, Varsha Jhawar, Helen I. Zgurskaya, Jerry M. Parks, Adam T. Green, Jerome Baudry, Valentin V. Rybenkov, Jeremy C. Smith, John K. Walker	2017	36
8	New Fluorobutenolide Templates for Synthesis The Journal of Organic Chemistry ·Timothy B. Patrick, Margaret V. Lanahan, Changqing Yang, John K. Walker, Claudine L. Hutchinson, Bradley E. Neal	1994	36
9	Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors Accounts of Chemical Research ·Helen I. Zgurskaya, John K. Walker, Jerry M. Parks, Valentin V. Rybenkov	2021	35
10	Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold Biochimica et Biophysica Acta (BBA) - General Subjects ·Adam T. Green, Mohammad Moniruzzaman, Connor J. Cooper, John K. Walker, Jeremy C. Smith, Jerry M. Parks, Helen I. Zgurskaya	2020	34
11	Discovery and Characterization of Atropisomer PH‐797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate ChemMedChem ·Xing Li, Balekudru Devadas, Rajesh Devraj, Shaun R. Selness, H.-S. Shieh, John K. Walker, Michael K. Mao, Dean Messing, Brian Samas, Jerry Z. Yang, Gary D. Anderson, Elizabeth Webb, Joseph B. Monahan	2011	32
12	Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism ACS Chemical Neuroscience ·Yongjun Wang, Cyrielle Billon, John K. Walker, Thomas P. Burris	2015	30
13	Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria Journal of Chemical Information and Modeling ·Rachael A. Mansbach, Inga V. Leus, Jitender Mehla, César A. López, John K. Walker, Valentin V. Rybenkov, Nicolas Hengartner, Helen I. Zgurskaya, S. Gnanakaran	2020	23
14	1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors Bioorganic & Medicinal Chemistry Letters ·Michael B. Tollefson, Brad A. Acker, E. Jon Jacobsen, Robert Hughes, John K. Walker, David Fox, Michael Palmer, Sandra K. Freeman, Ying Yu, Brian R. Bond	2010	21
15	GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain Journal of Pharmacology and Experimental Therapeutics ·Kathryn Braden, Luigino Antonio Giancotti, Zhoumou Chen, Chelsea DeLeon, Nick Latzo, Terri Boehm, Napoleon D’Cunha, Bonne M. Thompson, Timothy M. Doyle, Jeffrey G. McDonald, John K. Walker, Grant R. Kolar, Christopher K. Arnatt, Daniela Salvemini	2020	21
16	Effects of CEES on inflammatory mediators, heat shock protein 70A, histology and ultrastructure in two skin models†** Journal of Applied Toxicology ·M. Bláha, W. Bowers, J. Kohl, David A. DuBose, John K. Walker, A. Alkhyyat, Geraldine Wong	2001	21
17	Cationic [5+2] cycloaddition reactions promoted by trimethylsilyl triflate in highly polar media Tetrahedron Letters ·Jon L. Collins, Paul A. Grieco, John K. Walker	1997	21
18	Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB Nature Communications ·Meghan H. Murray, Aurore Valfort, Thomas Koelblen, Céline Ronin, Fabrice Ciesielski, Arindam Chatterjee, Giri Babu Veerakanellore, Bahaa Elgendy, John K. Walker, Lamees Hegazy, Thomas P. Burris	2022	20
19	Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase Bioorganic & Medicinal Chemistry Letters ·John K. Walker, Shaun R. Selness, Rajesh Devraj, Michael Hepperle, Win Naing, H.-S. Shieh, Ravi Kurambail, Syaulan Yang, Daniel L. Flynn, Alan G. Benson, Dean Messing, Tom Dice, Tina Kim, R. J. Lindmark, Joseph B. Monahan, Joseph P. Portanova	2010	19
20	Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity ACS Chemical Biology ·Cyrielle Billon, Sadichha Sitaula, Subhashis Banerjee, Ryan D. Welch, Bahaa Elgendy, Lamees Hegazy, Tae Gyu Oh, Melissa Kazantzis, Arindam Chatterjee, John C. Chrivia, Matthew Hayes, Weiyi Xu, Angelica Hamilton, Janice M. Huss, Lilei Zhang, John K. Walker, Michael Downes, Ronald M. Evans, Thomas P. Burris	2023	19

About John K. Walker

John K. Walker is a scholar working on Molecular Biology, Organic Chemistry, Molecular Medicine, Immunology and Genetics, having authored 49 papers that have together received 1.1k indexed citations. Recurring topics across this work include Antibiotic Resistance in Bacteria (10 papers), Phenothiazines and Benzothiazines Synthesis and Activities (7 papers), Receptor Mechanisms and Signaling (5 papers), Synthesis and biological activity (5 papers), Melanoma and MAPK Pathways (4 papers), Estrogen and related hormone effects (4 papers), Computational Drug Discovery Methods (4 papers) and Antibiotics Pharmacokinetics and Efficacy (4 papers). The work is most often cited by research in Molecular Medicine (216 citations), Cancer Research (114 citations), Microbiology (46 citations), Molecular Biology (483 citations) and Organic Chemistry (193 citations). John K. Walker has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Helen I. Zgurskaya, Jerry M. Parks, Valentin V. Rybenkov, Thomas P. Burris, Arindam Chatterjee, Bahaa Elgendy, Melissa Kazantzis, David Wolloscheck, Jeremy C. Smith and Connor J. Cooper. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Infectious Diseases, The Journal of Immunology, ACS Chemical Biology and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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