Sergio Grinstein

67.0k total citations · 18 hit papers
578 papers, 53.1k citations indexed

About

Sergio Grinstein is a scholar working on Molecular Biology, Cell Biology and Immunology. According to data from OpenAlex, Sergio Grinstein has authored 578 papers receiving a total of 53.1k indexed citations (citations by other indexed papers that have themselves been cited), including 371 papers in Molecular Biology, 165 papers in Cell Biology and 157 papers in Immunology. Recurrent topics in Sergio Grinstein's work include Cellular transport and secretion (130 papers), Lipid Membrane Structure and Behavior (119 papers) and Ion channel regulation and function (107 papers). Sergio Grinstein is often cited by papers focused on Cellular transport and secretion (130 papers), Lipid Membrane Structure and Behavior (119 papers) and Ion channel regulation and function (107 papers). Sergio Grinstein collaborates with scholars based in Canada, United States and Germany. Sergio Grinstein's co-authors include John Orlowski, Wendy Furuya, A. Rothstein, Joseph R. Casey, Erwin W. Gelfand, Ronald S. Flannagan, Spencer A. Freeman, Ori D. Rotstein, Roberto J. Botelho and William S. Trimble and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Sergio Grinstein

574 papers receiving 52.1k citations

Hit Papers

Sensors and regulators of intracellu... 1986 2026 1999 2012 2009 2008 2008 2010 2011 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Sensors and regulators of intracellular pH
    2009 1.8k citations Sergio Grinstein, John Orlowski et al. profile →
  2. Robust single-particle tracking in live-cell time-lapse sequences
    2008 1.4k citations Sergio Grinstein et al. profile →
  3. Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization
    2008 843 citations Sergio Grinstein et al. Science profile →
  4. The Distribution and Function of Phosphatidylserine in Cellular Membranes
    2010 774 citations Sergio Grinstein et al. profile →
  5. The Cell Biology of Phagocytosis
    2011 729 citations Ronald S. Flannagan, Valentin Jaumouillé et al. Annual Review of Pathology Mechanisms of Disease profile →
  6. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
    2010 717 citations Cameron C. Scott, Sergio Grinstein et al. The Journal of Cell Biology profile →
  7. Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
    2009 702 citations Ronald S. Flannagan, Sergio Grinstein et al. profile →
  8. Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation
    1989 666 citations Sergio Grinstein et al. profile →
  9. Scavenger receptors in homeostasis and immunity
    2013 621 citations Sergio Grinstein et al. profile →
  10. Mechanisms of regulation of the Na+/H+ exchanger
    1986 585 citations Sergio Grinstein et al. profile →
  11. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
    2006 553 citations Benjamin E. Steinberg, Sergio Grinstein et al. profile →
  12. Phagosome maturation: aging gracefully
    2002 538 citations Roberto J. Botelho, Sergio Grinstein et al. profile →
  13. LAMP proteins are required for fusion of lysosomes with phagosomes
    2007 520 citations Cameron C. Scott, Sergio Grinstein et al. profile →
  14. Diversity of the mammalian sodium/proton exchanger SLC9 gene family
    2004 517 citations John Orlowski, Sergio Grinstein Pflügers Archiv - European Journal of Physiology profile →
  15. The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
    1998 495 citations Sergio Grinstein et al. profile →
  16. The position of lysosomes within the cell determines their luminal pH
    2016 422 citations Danielle Johnson, Philip P. Ostrowski et al. The Journal of Cell Biology profile →
  17. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
    2018 151 citations Spencer A. Freeman, Richard F. Collins et al. Cell profile →
  18. Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
    2023 149 citations Benjamin E. Steinberg, Sergio Grinstein et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sergio Grinstein Canada 118 28.9k 12.6k 10.4k 7.4k 4.5k 578 53.1k
Paul Tempst United States 143 62.1k 2.2× 9.0k 0.7× 8.7k 0.8× 7.7k 1.0× 4.9k 1.1× 320 80.8k
Simon C. Watkins United States 126 28.3k 1.0× 12.9k 1.0× 6.0k 0.6× 7.8k 1.1× 6.7k 1.5× 788 59.2k
Ira Pastan United States 146 45.5k 1.6× 20.3k 1.6× 7.5k 0.7× 3.5k 0.5× 3.8k 0.9× 1.2k 90.1k
Junying Yuan United States 103 36.5k 1.3× 10.4k 0.8× 8.1k 0.8× 4.3k 0.6× 10.9k 2.4× 254 52.9k
Yusuf A. Hannun United States 127 51.4k 1.8× 6.2k 0.5× 13.5k 1.3× 10.9k 1.5× 4.7k 1.0× 570 62.0k
John C. Reed United States 161 73.3k 2.5× 20.4k 1.6× 10.1k 1.0× 4.6k 0.6× 10.6k 2.4× 799 107.5k
Hediye Erdjument‐Bromage United States 125 53.4k 1.8× 6.9k 0.5× 7.7k 0.7× 6.7k 0.9× 4.7k 1.1× 285 68.1k
Guy S. Salvesen United States 110 37.2k 1.3× 9.6k 0.8× 5.5k 0.5× 5.7k 0.8× 5.9k 1.3× 295 54.7k
Roger J. Davis United States 146 62.3k 2.2× 13.6k 1.1× 11.7k 1.1× 8.3k 1.1× 7.5k 1.7× 572 92.6k
Roderick T. Bronson United States 139 46.0k 1.6× 11.5k 0.9× 7.5k 0.7× 5.8k 0.8× 4.2k 0.9× 544 77.8k

Countries citing papers authored by Sergio Grinstein

Since Specialization
Citations

This map shows the geographic impact of Sergio Grinstein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sergio Grinstein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sergio Grinstein more than expected).

Fields of papers citing papers by Sergio Grinstein

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sergio Grinstein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sergio Grinstein. The network helps show where Sergio Grinstein may publish in the future.

Co-authorship network of co-authors of Sergio Grinstein

This figure shows the co-authorship network connecting the top 25 collaborators of Sergio Grinstein. A scholar is included among the top collaborators of Sergio Grinstein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sergio Grinstein. Sergio Grinstein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sydor, Andrew M., Étienne Coyaud, Estelle Laurent, et al.. (2024). Salmonella exploits membrane reservoirs for invasion of host cells. Nature Communications. 15(1). 3120–3120. 13 indexed citations
2.
Plumb, Jonathan, et al.. (2023). Lysosomal swelling and lysis mediate delivery of C3 toxins to their cytoplasmic targets. Molecular Microbiology. 119(6). 695–710. 1 indexed citations
3.
Wu, Jing, et al.. (2023). ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution. The Journal of Cell Biology. 222(6). 23 indexed citations
4.
Tan, Yong Zi, Y.M. Abbas, Jing Wu, et al.. (2022). CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7. Life Science Alliance. 5(11). e202201527–e202201527. 20 indexed citations
5.
Freeman, Spencer A. & Sergio Grinstein. (2021). Promoters and Antagonists of Phagocytosis: A Plastic and Tunable Response. Annual Review of Cell and Developmental Biology. 37(1). 89–114. 21 indexed citations
6.
López‐Haber, Cynthia, Yueyao Zhu, Jing Bi‐Karchin, et al.. (2020). Phosphatidylinositol-4-kinase IIα licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells. Proceedings of the National Academy of Sciences. 117(45). 28251–28262. 13 indexed citations
7.
Freeman, Spencer A., Stefan Uderhardt, Amra Sarić, et al.. (2019). Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science. 367(6475). 301–305. 104 indexed citations
8.
Grinstein, Sergio, et al.. (2019). Phagosome‐endoplasmic reticulum contacts: Kissing and not running. Traffic. 21(1). 172–180. 19 indexed citations
9.
Westman, Johannes, Gary P. Moran, Selene Mogavero, Bernhard Hube, & Sergio Grinstein. (2018). Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization. mBio. 9(5). 80 indexed citations
10.
O’Meara, Teresa R., Michelle E. Maxson, Ryan G. Gaudet, et al.. (2018). High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis. mBio. 9(4). 53 indexed citations
11.
Marques, Pedro Elias, Sergio Grinstein, & Spencer A. Freeman. (2017). SnapShot:Macropinocytosis. Cell. 169(4). 766–766.e1. 49 indexed citations
12.
Ostrowski, Philip P., Gregory D. Fairn, Sergio Grinstein, & Danielle Johnson. (2016). Cresyl violet: a superior fluorescent lysosomal marker. Traffic. 17(12). 1313–1321. 47 indexed citations
13.
Flannagan, Ronald S., Valentin Jaumouillé, & Sergio Grinstein. (2011). The Cell Biology of Phagocytosis. Annual Review of Pathology Mechanisms of Disease. 7(1). 61–98. 729 indexed citations breakdown →
14.
Huang, Ju, Veronica Canadien, Grace Y. Lam, et al.. (2009). Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences. 106(15). 6226–6231. 439 indexed citations
15.
Mason, David Y., et al.. (2006). Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane. The Journal of Cell Biology. 174(2). 255–265. 29 indexed citations
16.
Scott, Cameron C., Wendy Dobson, Roberto J. Botelho, et al.. (2005). Phosphatidylinositol-4,5- bis phosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169(1). 139–149. 206 indexed citations
17.
Orlowski, John & Sergio Grinstein. (2004). Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflügers Archiv - European Journal of Physiology. 447(5). 549–565. 517 indexed citations breakdown →
18.
Jongstra‐Bilen, Jenny, Rene E. Harrison, & Sergio Grinstein. (2003). Fcγ-receptors Induce Mac-1 (CD11b/CD18) Mobilization and Accumulation in the Phagocytic Cup for Optimal Phagocytosis. Journal of Biological Chemistry. 278(46). 45720–45729. 103 indexed citations
19.
Downey, Gregory P., Jeffrey Butler, Hans Tapper, et al.. (1998). Importance of MEK in Neutrophil Microbicidal Responsiveness. The Journal of Immunology. 160(1). 434–443. 140 indexed citations
20.
Mills, Gordon B., Roy K. Cheung, Sergio Grinstein, & Erwin W. Gelfand. (1985). Increase in cytosolic free calcium concentration is an intracellular messenger for the production of interleukin 2 but not for expression of the interleukin 2 receptor.. The Journal of Immunology. 134(3). 1640–1643. 144 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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