Frederick R. Maxfield

35.5k total citations · 10 hit papers
261 papers, 29.3k citations indexed

About

Frederick R. Maxfield is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, Frederick R. Maxfield has authored 261 papers receiving a total of 29.3k indexed citations (citations by other indexed papers that have themselves been cited), including 151 papers in Molecular Biology, 107 papers in Cell Biology and 60 papers in Physiology. Recurrent topics in Frederick R. Maxfield's work include Cellular transport and secretion (72 papers), Lipid Membrane Structure and Behavior (71 papers) and Cholesterol and Lipid Metabolism (32 papers). Frederick R. Maxfield is often cited by papers focused on Cellular transport and secretion (72 papers), Lipid Membrane Structure and Behavior (71 papers) and Cholesterol and Lipid Metabolism (32 papers). Frederick R. Maxfield collaborates with scholars based in United States, Canada and France. Frederick R. Maxfield's co-authors include Sushmita Mukherjee, Timothy E. McGraw, Ira Tabas, Satyajit Mayor, Ira Pastan, Mark C. Willingham, Daniel Wüstner, Benjamin Tycko, Rahul Ghosh and Darrell J. Yamashiro and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Frederick R. Maxfield

258 papers receiving 28.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Endocytic recycling

2004 1.4k citations Frederick R. Maxfield, Timothy E. McGraw Nature Reviews Molecular Cell Biology profile →
Endocytosis

1997 1.1k citations Sushmita Mukherjee, Frederick R. Maxfield et al. profile →
Role of cholesterol and lipid organization in disease

2005 1.1k citations Frederick R. Maxfield et al. profile →
Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 743 citations Frederick R. Maxfield et al. Journal of Biological Chemistry profile →
Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

1996 570 citations Frederick R. Maxfield et al. profile →
Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 551 citations Frederick R. Maxfield et al. profile →
Membrane transport in the endocytic pathway

1995 532 citations Frederick R. Maxfield et al. profile →
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 511 citations Frederick R. Maxfield profile →
Segregation of transferrin to a mildly acidic (pH 6.5) para-golgi compartment in the recycling pathway

1984 509 citations Frederick R. Maxfield et al. profile →
Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 476 citations Frederick R. Maxfield et al. profile →

Peers

Countries citing papers authored by Frederick R. Maxfield

Since Specialization

Citations

This map shows the geographic impact of Frederick R. Maxfield's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frederick R. Maxfield with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frederick R. Maxfield more than expected).

Fields of papers citing papers by Frederick R. Maxfield

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frederick R. Maxfield. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frederick R. Maxfield. The network helps show where Frederick R. Maxfield may publish in the future.

Co-authorship network of co-authors of Frederick R. Maxfield

This figure shows the co-authorship network connecting the top 25 collaborators of Frederick R. Maxfield. A scholar is included among the top collaborators of Frederick R. Maxfield based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frederick R. Maxfield. Frederick R. Maxfield is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding 2025 ·Journal of Clinical Investigation ·(unknown), Mattia Malvezzi, Lala Tanmoy Das, (unknown), (unknown), (unknown), Steven O. Marx, Frederick R. Maxfield, Geoffrey S. Pitt	0
2	Itraconazole and posaconazole, inhibitors of NPC1 sterol transport, act as pharmacological chaperones after washout 2025 ·Journal of Biological Chemistry ·(unknown), (unknown), (unknown), Frederick R. Maxfield	1
3	High-Content Microscopy Drug Screening Platform for Regulators of the Extracellular Digestion of Lipoprotein Aggregates by Macrophages 2025 ·ACS Pharmacology & Translational Science ·(unknown), (unknown), (unknown), Frederick R. Maxfield	1
4	Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy 2024 ·Cell Reports ·(unknown), Fernando Gonzàlez Ibáñez, Katherine Picard, (unknown), (unknown), Gunnar K. Gouras, Marie‐Ève Tremblay, Frederick R. Maxfield, Santiago Solé‐Domènech	10
5	The formation and consequences of cholesterol-rich deposits in atherosclerotic lesions 2023 ·Frontiers in Cardiovascular Medicine ·Frederick R. Maxfield, (unknown), (unknown)	16
6	Signaling pathways regulating the extracellular digestion of lipoprotein aggregates by macrophages 2023 ·Molecular Biology of the Cell ·(unknown), (unknown), Frederick R. Maxfield	7
7	Digestive exophagy: Phagocyte digestion of objects too large for phagocytosis 2019 ·Traffic ·Frederick R. Maxfield, Valéria C. Barbosa-Lorenzi, Rajesh Kumar Singh	20
8	Progranulin in the hematopoietic compartment protects mice from atherosclerosis 2018 ·Atherosclerosis ·Andrew D. Nguyen, Anh Thi Nguyen, Raj Singh, Delphine Eberlé, Jiasheng Zhang, (unknown), (unknown), Suneil K. Koliwad, Eric J. Huang, Frederick R. Maxfield, Tobias C. Walther, Robert V. Farese	13
9	Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing 2017 ·Nature Medicine ·Miguel Crespo, Eduardo Vilar, Su‐Yi Tsai, Kyle Chang, Sadaf Amin, Tara Srinivasan, Tuo Zhang, Nina H. Pipalia, Huanhuan Joyce Chen, Mavee Witherspoon, Miriam Gordillo, Jenny Xiang, Frederick R. Maxfield, Steven M. Lipkin, Todd Evans, Shuibing Chen	293
10	Lysosomes : biology, diseases, and therapeutics 2016 ·Wiley eBooks ·Frederick R. Maxfield, James M. Willard, Shuyan Lu	5
11	A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele 2015 ·Journal of Neuroscience ·(unknown), Brett A. Tortelli, Jessie Zhang, Hideji Fujiwara, Rohini Sidhu, (unknown), Zhouji Chen, Chan Chung, Andrew P. Lieberman, Jakub Sikora, Cristin Davidson, Steven U. Walkley, Nina H. Pipalia, Frederick R. Maxfield, Jean E. Schaffer, Daniel Ory	93
12	STARD4 abundance regulates sterol transport and sensing 2011 ·Molecular Biology of the Cell ·Bruno Mesmin, Nina H. Pipalia, Frederik W. Lund, Trudy F. Ramlall, (unknown), David Eliezer, Frederick R. Maxfield	101
13	Multiphoton Microscopy of Prostate and Periprostatic Neural Tissue: A Promising Imaging Technique for Improving Nerve-Sparing Prostatectomy 2009 ·Journal of Endourology ·Rajiv Yadav, Sushmita Mukherjee, (unknown), Gerald Tan, Frederick R. Maxfield, Watt W. Webb, Ashutosh Tewari	43
14	Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins 2009 ·Molecular Biology of the Cell ·Abigail S. Haka, Inna Grosheva, Ethan N. Chiang, Adina R. Buxbaum, Barbara Baird, Lynda M. Pierini, Frederick R. Maxfield	102
15	Sterols Are Mainly in the Cytoplasmic Leaflet of the Plasma Membrane and the Endocytic Recycling Compartment in CHO Cells 2008 ·Molecular Biology of the Cell ·Mousumi Mondal, Bruno Mesmin, Sushmita Mukherjee, Frederick R. Maxfield	160
16	Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells 2004 ·Journal of Lipid Research ·Daniel Wüstner, Mousumi Mondal, Amy Y. Huang, Frederick R. Maxfield	67
17	Endocytic recycling breakdown → 2004 ·Nature Reviews Molecular Cell Biology ·Frederick R. Maxfield, Timothy E. McGraw	1444
18	Intracellular cholesterol transport 2002 ·Journal of Clinical Investigation ·Frederick R. Maxfield, Daniel Wüstner	236
19	Intracellular cholesterol transport 2002 ·Journal of Clinical Investigation ·Frederick R. Maxfield, Daniel Wüstner	14
20	Effects of buffering intracellular free calcium on neutrophil migration through three-dimensional matrices 1997 ·Journal of Cellular Physiology ·John Mandeville, Frederick R. Maxfield	37

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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