Sabina Signoretti

96.3k total citations · 10 hit papers
296 papers, 20.4k citations indexed

About

Sabina Signoretti is a scholar working on Pulmonary and Respiratory Medicine, Molecular Biology and Oncology. According to data from OpenAlex, Sabina Signoretti has authored 296 papers receiving a total of 20.4k indexed citations (citations by other indexed papers that have themselves been cited), including 180 papers in Pulmonary and Respiratory Medicine, 147 papers in Molecular Biology and 135 papers in Oncology. Recurrent topics in Sabina Signoretti's work include Renal cell carcinoma treatment (144 papers), Cancer Genomics and Diagnostics (75 papers) and Renal and related cancers (64 papers). Sabina Signoretti is often cited by papers focused on Renal cell carcinoma treatment (144 papers), Cancer Genomics and Diagnostics (75 papers) and Renal and related cancers (64 papers). Sabina Signoretti collaborates with scholars based in United States, Canada and Italy. Sabina Signoretti's co-authors include Massimo Loda, Michael B. Atkins, Toni K. Choueiri, Laurence Albigès, Daniel Y.C. Heng, James J. Hsieh, James Larkin, Vincenzo Ficarra, Manuela Schmidinger and Charles Swanton and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Sabina Signoretti

288 papers receiving 20.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Renal cell carcinoma

2017 1.8k citations Sabina Signoretti, Laurence Albigès et al. profile →
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

2016 1.6k citations Jean‐Christophe Pignon, Sabina Signoretti et al. profile →
Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion

2005 671 citations Arnold H. Zea, Paulo C. Rodrı́guez et al. Cancer Research profile →
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

2019 663 citations Sabina Signoretti, Toni K. Choueiri et al. profile →
Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis

2008 553 citations Sabina Signoretti, Massimo Loda et al. profile →
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

2016 336 citations Wenhua Gao, Ingrid Carvo et al. profile →
Genetic and Functional Studies Implicate HIF1 α as a 14q Kidney Cancer Suppressor Gene

2011 313 citations Chuan Shen, Rameen Beroukhim et al. Cancer Discovery profile →
Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney

2009 310 citations Rameen Beroukhim, Arianna Di Napoli et al. Cancer Research profile →
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

2019 280 citations Michael Tolstorukov, Rameen Beroukhim et al. profile →
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

2016 193 citations Sabina Signoretti, Andrea L. Richardson et al. profile →

Peers

Countries citing papers authored by Sabina Signoretti

Since Specialization

Citations

This map shows the geographic impact of Sabina Signoretti's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sabina Signoretti with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sabina Signoretti more than expected).

Fields of papers citing papers by Sabina Signoretti

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sabina Signoretti. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sabina Signoretti. The network helps show where Sabina Signoretti may publish in the future.

Co-authorship network of co-authors of Sabina Signoretti

This figure shows the co-authorship network connecting the top 25 collaborators of Sabina Signoretti. A scholar is included among the top collaborators of Sabina Signoretti based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sabina Signoretti. Sabina Signoretti is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Phase II study of nivolumab and salvage nivolumab/ipilimumab in treatment-naïve patients with advanced non-clear cell renal cell carcinoma (HCRN GU16-260-Cohort B) 2023 ·Journal for ImmunoTherapy of Cancer ·Michael B. Atkins, Opeyemi A. Jegede, Naomi B. Haas, David F. McDermott, Mehmet Asım Bilen, Mark N. Stein, Jeffrey A. Sosman, Robert Alter, Elizabeth R. Plimack, Moshe Chaim Ornstein, Michael E. Hurwitz, David Peace, Sabina Signoretti, Thomas Denize, Alessia Cimadamore, Catherine J. Wu, David A. Braun, David J. Einstein, Paul J. Catalano, Hans J. Hammers	19
2	Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma 2022 ·Clinical Cancer Research ·Thomas Denize, Yue Hou, Jean‐Christophe Pignon, Emily Walton, (unknown), Gordon J. Freeman, David A. Braun, Catherine J. Wu, Saurabh Gupta, Robert J. Motzer, Michael B. Atkins, David F. McDermott, Toni K. Choueiri, Sachet A. Shukla, Sabina Signoretti	13
3	Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer 2021 ·Cancer Research ·Deli Hong, Erik H. Knelson, Yixiang Li, (unknown), Wenhua Gao, Emily Walton, Amir Vajdi, Tran C. Thai, Maura Sticco-Ivins, (unknown), Kristen L. Jones, Anna C. Schinzel, Rod T. Bronson, Quang‐Dé Nguyen, Michael Tolstorukov, Marina Vivero, Sabina Signoretti, David A. Barbie, Matthew G. Oser	25
4	KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1 2020 ·Cancer Immunology Research ·Rupal S. Bhatt, (unknown), (unknown), Kathleen M. Mahoney, (unknown), Samuel S. Freeman, Chun-Hau Chen, Opeyemi A. Jegede, Paul J. Catalano, Jean‐Christophe Pignon, Maura Sticco-Ivins, Baogong Zhu, Ping Hua, Jo Soden, Jie Zhu, David F. McDermott, Antonio R. Arulanandam, Sabina Signoretti, Gordon J. Freeman	80
5	Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma 2019 ·Molecular Cancer Therapeutics ·Amin H. Nassar, Lana Hamieh, Kathryn P. Gray, Aaron R. Thorner, André P. Fay, (unknown), Sarah Abou Alaiwi, Pier Vitale Nuzzo, Ronan Flippot, Katherine M. Krajewski, Sabina Signoretti, Toni K. Choueiri, David J. Kwiatkowski	10
6	FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma 2016 ·Clinical Cancer Research ·Amy K. Erbe, Wei Wang, Jacob L. Goldberg, (unknown), KyungMann Kim, Lakeesha Carmichael, (unknown), Eneida A. Mendonça, (unknown), Jacquelyn A. Hank, Su–Chun Cheng, Sabina Signoretti, Michael B. Atkins, (unknown), James W. Mier, David J. Panka, David F. McDermott, Paul M. Sondel	12
7	Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer 2015 ·Clinical Cancer Research ·(unknown), Xiaoen Wang, Andrea J. Bullock, Marcella Callea, (unknown), Jiaxi Song, Kelli Moreno, Barbara Visentin, Douglas H. Deutschman, David C. Alsop, Michael B. Atkins, James W. Mier, Sabina Signoretti, Manoj Bhasin, Roger A. Sabbadini, Rupal S. Bhatt	67
8	Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma 2015 ·Cancer Immunology Research ·Marcella Callea, Laurence Albigès, Mamta Gupta, Su–Chun Cheng, Elizabeth M. Genega, André P. Fay, Jiaxi Song, Ingrid Carvo, Rupal S. Bhatt, Michael B. Atkins, F. Stephen Hodi, Toni K. Choueiri, David F. McDermott, Gordon J. Freeman, Sabina Signoretti	266
9	RNA-seq Reveals Aurora Kinase–Driven mTOR Pathway Activation in Patients with Sarcomatoid Metastatic Renal Cell Carcinoma 2014 ·Molecular Cancer Research ·Sumanta K. Pal, Miaoling He, Tommy R. Tong, Huiqing Wu, Xueli Liu, Clayton Lau, Jinhui Wang, Charles Warden, Xiwei Wu, Sabina Signoretti, Toni K. Choueiri, José A. Karam, Jeremy O. Jones	37
10	Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee 2013 ·Cancer Research ·Michael Ittmann, Jiaoti Huang, Enrico Radaelli, Philip Martin, Sabina Signoretti, Ruth Sullivan, Brian W. Simons, Jerrold M. Ward, Brian D. Robinson, Gerald C. Chu, Massimo Loda, George Thomas, Alexander D. Borowsky, Robert D. Cardiff	184
11	The Role of Aberrant VHL/HIF Pathway Elements in Predicting Clinical Outcome to Pazopanib Therapy in Patients with Metastatic Clear-Cell Renal Cell Carcinoma 2013 ·Clinical Cancer Research ·Toni K. Choueiri, André P. Fay, Robert Gagnon, Ying Lin, Brittany Bahamón, Victoria E. Brown, Jonathan E. Rosenberg, Thomas E. Hutson, Katherine L. Baker-Neblett, Christopher L. Carpenter, Yuan Liu, Lini Pandite, Sabina Signoretti	73
12	Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow–Derived Cells 2012 ·Cancer Discovery ·Hanna S. Kuznetsov, Timothy Marsh, Beth A. Markens, Zafira Castaño, April Greene-Colozzi, (unknown), Victoria E. Brown, Andrea L. Richardson, Sabina Signoretti, Elisabeth M. Battinelli, Sandra S. McAllister	134
13	Genetic and Functional Studies Implicate HIF1 α as a 14q Kidney Cancer Suppressor Gene breakdown → 2011 ·Cancer Discovery ·Chuan Shen, Rameen Beroukhim, Steven E. Schumacher, Jing Zhou, Michelle Chang, Sabina Signoretti, William G. Kaelin	313
14	Renal Cancer Resistance to Antiangiogenic Therapy Is Delayed by Restoration of Angiostatic Signaling 2010 ·Molecular Cancer Therapeutics ·Rupal S. Bhatt, Xiaoen Wang, Liang Zhang, Michael P. Collins, Sabina Signoretti, David C. Alsop, S. Nahum Goldberg, Michael B. Atkins, James W. Mier	48
15	The Efficacy of the Novel Dual PI3-Kinase/mTOR Inhibitor NVP-BEZ235 Compared with Rapamycin in Renal Cell Carcinoma 2010 ·Clinical Cancer Research ·Daniel C. Cho, (unknown), David J. Panka, Michael P. Collins, Musie Ghebremichael, Michael B. Atkins, Sabina Signoretti, James W. Mier	154
16	Reciprocal Effects of STAT5 and STAT3 in Breast Cancer 2009 ·Molecular Cancer Research ·Sarah R. Walker, Erik A. Nelson, Lihua Zou, (unknown), Sabina Signoretti, Andrea L. Richardson, David A. Frank	107
17	Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney breakdown → 2009 ·Cancer Research ·Rameen Beroukhim, (unknown), Arianna Di Napoli, Kirsten D. Mertz, Apryle Seeley, Maira M. Pires, David Linhart, Robert Worrell, Holger Moch, Mark A. Rubin, William R. Sellers, Matthew Meyerson, W. Marston Linehan, William G. Kaelin, Sabina Signoretti	310
18	Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion breakdown → 2005 ·Cancer Research ·Arnold H. Zea, Paulo C. Rodrı́guez, Michael B. Atkins, Claudia Hernandez, Sabina Signoretti, Jovanny Zabaleta, David F. McDermott, David Quiceno, Amanda Youmans, Anne O’Neill, James W. Mier, Augusto C. Ochoa	671
19	p63 regulates commitment to the prostate cell lineage 2005 ·Proceedings of the National Academy of Sciences ·Sabina Signoretti, Maira M. Pires, (unknown), James W. Horner, Chiara Grisanzio, (unknown), Pradip K. Majumder, Frank McKeon, Philip W. Kantoff, William R. Sellers, Massimo Loda	121
20	Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells 2004 ·Cancer Research ·Raanan Berger, Phillip G. Febbo, Pradip K. Majumder, Jean J. Zhao, Sayan Mukherjee, Sabina Signoretti, Katrina Campbell, William R. Sellers, Thomas M. Roberts, Massimo Loda, Todd R. Golub, William C. Hahn	140

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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