W. Marston Linehan

89.1k total citations · 16 hit papers
586 papers, 44.9k citations indexed

About

W. Marston Linehan is a scholar working on Pulmonary and Respiratory Medicine, Molecular Biology and Cancer Research. According to data from OpenAlex, W. Marston Linehan has authored 586 papers receiving a total of 44.9k indexed citations (citations by other indexed papers that have themselves been cited), including 352 papers in Pulmonary and Respiratory Medicine, 316 papers in Molecular Biology and 196 papers in Cancer Research. Recurrent topics in W. Marston Linehan's work include Renal cell carcinoma treatment (294 papers), Renal and related cancers (213 papers) and Cancer, Hypoxia, and Metabolism (117 papers). W. Marston Linehan is often cited by papers focused on Renal cell carcinoma treatment (294 papers), Renal and related cancers (213 papers) and Cancer, Hypoxia, and Metabolism (117 papers). W. Marston Linehan collaborates with scholars based in United States, United Kingdom and France. W. Marston Linehan's co-authors include McClellan M. Walther, Berton Zbar, Maria J. Merino, Peter L. Choyke, Laura S. Schmidt, Peter A. Pinto, Ramaprasad Srinivasan, Christopher J. Ricketts, G.M. Glenn and Gennady Bratslavsky and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

W. Marston Linehan

574 papers receiving 43.7k citations

Hit Papers

A Progress Report on the Treatment of 157 Patients with A... 1987 2026 2000 2013 1987 1994 2015 2011 2002 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone
    1987 2.2k citations Steven A. Rosenberg, Michael T. Lotze et al. profile →
  2. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.
    1994 1.3k citations Michael I. Lerman, Berton Zbar et al. profile →
  3. Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer
    2015 1.1k citations W. Marston Linehan, Maria J. Merino et al. profile →
  4. Reductive carboxylation supports growth in tumour cells with defective mitochondria
    2011 1.0k citations W. Marston Linehan et al. profile →
  5. Biochemical Diagnosis of Pheochromocytoma
    2002 792 citations Karel Pacák, W. Marston Linehan et al. profile →
  6. Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients
    1989 786 citations Steven A. Rosenberg, Michael T. Lotze et al. Annals of Surgery profile →
  7. Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell Transplantation
    2000 770 citations W. Marston Linehan et al. profile →
  8. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
    2005 732 citations Maria J. Merino, Berton Zbar et al. profile →
  9. Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome
    2002 638 citations Jorge R. Toro, G.M. Glenn et al. profile →
  10. The genetic basis of kidney cancer: a metabolic disease
    2010 550 citations W. Marston Linehan, Ramaprasad Srinivasan et al. Nature Reviews Urology profile →
  11. MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis
    2020 530 citations W. Marston Linehan, Maria J. Merino et al. profile →
  12. Ionic immune suppression within the tumour microenvironment limits T cell effector function
    2016 489 citations W. Marston Linehan et al. profile →
  13. The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications
    2019 402 citations W. Marston Linehan, Christopher J. Ricketts Nature Reviews Urology profile →
  14. Multiparametric 3T Prostate Magnetic Resonance Imaging to Detect Cancer: Histopathological Correlation Using Prostatectomy Specimens Processed in Customized Magnetic Resonance Imaging Based Molds
    2011 383 citations W. Marston Linehan, Maria J. Merino et al. profile →
  15. Magnetic Resonance Imaging/Ultrasound Fusion Guided Prostate Biopsy Improves Cancer Detection Following Transrectal Ultrasound Biopsy and Correlates With Multiparametric Magnetic Resonance Imaging
    2011 351 citations W. Marston Linehan, Peter L. Choyke et al. profile →
  16. Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney
    2009 310 citations Rameen Beroukhim, Arianna Di Napoli et al. Cancer Research profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
W. Marston Linehan United States 113 22.2k 20.9k 13.0k 7.9k 7.5k 586 44.9k
Maria J. Merino United States 98 12.3k 0.6× 17.3k 0.8× 7.1k 0.5× 5.5k 0.7× 8.1k 1.1× 593 37.5k
Angelo M. De Marzo United States 98 16.9k 0.8× 14.1k 0.7× 10.5k 0.8× 3.5k 0.4× 8.9k 1.2× 443 35.0k
Razelle Kurzrock United States 119 21.0k 0.9× 12.3k 0.6× 13.3k 1.0× 4.5k 0.6× 24.9k 3.3× 1.2k 60.4k
Holger Moch Switzerland 91 18.3k 0.8× 14.7k 0.7× 9.7k 0.7× 6.3k 0.8× 11.4k 1.5× 604 36.5k
Carlos Cordon‐Cardo United States 129 41.4k 1.9× 11.0k 0.5× 12.8k 1.0× 7.7k 1.0× 22.8k 3.0× 564 68.1k
David Sidransky United States 121 40.0k 1.8× 9.6k 0.5× 17.1k 1.3× 9.1k 1.2× 25.6k 3.4× 576 66.1k
Paul Kleihues Switzerland 79 19.8k 0.9× 8.5k 0.4× 11.7k 0.9× 3.6k 0.5× 7.8k 1.0× 296 53.7k
Masaki Mori Japan 93 21.3k 1.0× 9.6k 0.5× 12.4k 1.0× 9.8k 1.2× 12.0k 1.6× 1.3k 43.4k
Charles L. Sawyers United States 99 24.8k 1.1× 15.9k 0.8× 9.3k 0.7× 1.4k 0.2× 12.3k 1.6× 266 53.4k
Martin Gleave Canada 98 15.6k 0.7× 15.8k 0.8× 8.7k 0.7× 2.2k 0.3× 9.0k 1.2× 680 32.4k

Countries citing papers authored by W. Marston Linehan

Since Specialization
Citations

This map shows the geographic impact of W. Marston Linehan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by W. Marston Linehan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites W. Marston Linehan more than expected).

Fields of papers citing papers by W. Marston Linehan

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by W. Marston Linehan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by W. Marston Linehan. The network helps show where W. Marston Linehan may publish in the future.

Co-authorship network of co-authors of W. Marston Linehan

This figure shows the co-authorship network connecting the top 25 collaborators of W. Marston Linehan. A scholar is included among the top collaborators of W. Marston Linehan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with W. Marston Linehan. W. Marston Linehan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Assmann, Julian C., Don Farthing, Keita Saito, et al.. (2021). Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by 13C-MRI. Blood. 137(1). 126–137. 25 indexed citations
2.
Maio, Nunziata, Bernard A. P. Lafont, Debangsu Sil, et al.. (2021). Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets. Science. 373(6551). 236–241. 82 indexed citations
3.
Xu, Yang, Paul Taylor, Joshua Andrade, et al.. (2018). Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Research. 78(23). 6539–6548. 14 indexed citations
4.
Damayanti, Nur P., Justin A. Budka, Heba Khella, et al.. (2018). Therapeutic Targeting of TFE3/IRS-1/PI3K/mTOR Axis in Translocation Renal Cell Carcinoma. Clinical Cancer Research. 24(23). 5977–5989. 61 indexed citations
5.
Fliedner, Stephanie, Uma Shankavaram, Abdel Elkahloun, et al.. (2016). Hypoxia-Inducible Factor 2α Mutation-Related Paragangliomas Classify as Discrete Pseudohypoxic Subcluster. Neoplasia. 18(9). 567–576. 15 indexed citations
6.
Linehan, W. Marston & Christopher J. Ricketts. (2016). RCC — advances in targeted therapeutics and genomics. Nature Reviews Urology. 14(2). 76–78. 12 indexed citations
7.
Cherkasova, Elena, Yoshiyuki Takahashi, Nanae Harashima, et al.. (2016). Detection of an Immunogenic HERV-E Envelope with Selective Expression in Clear Cell Kidney Cancer. Cancer Research. 76(8). 2177–2185. 92 indexed citations
8.
Srivastava, Apurva K., Melinda G. Hollingshead, Jennifer Weiner, et al.. (2016). Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays. Clinical Cancer Research. 22(14). 3683–3694. 24 indexed citations
9.
Linehan, W. Marston & Tracey A. Rouault. (2013). Molecular Pathways: Fumarate Hydratase-Deficient Kidney Cancer—Targeting the Warburg Effect in Cancer. Clinical Cancer Research. 19(13). 3345–3352. 162 indexed citations
10.
Schmidt, Laura S., Jessica L. Mester, Samuel Peña‐Llopis, et al.. (2013). A Novel Germline Mutation in BAP1 Predisposes to Familial Clear-Cell Renal Cell Carcinoma. Molecular Cancer Research. 11(9). 1061–1071. 113 indexed citations
11.
Jacobs-El, Naima, Emily Y. Chew, Ramaprasad Srinivasan, et al.. (2012). Systemic Sunitinib Malate in the Treatment of Optic Nerve Hemangioblastomas. Investigative Ophthalmology & Visual Science. 53(14). 4940–4940. 1 indexed citations
12.
Sudarshan, Sunil, José A. Karam, James Brugarolas, et al.. (2012). Metabolism of Kidney Cancer: From the Lab to Clinical Practice. European Urology. 63(2). 244–251. 61 indexed citations
13.
Woldemichael, Girma M., Thomas J. Turbyville, W. Marston Linehan, & James B. McMahon. (2011). Carminomycin I Is an Apoptosis Inducer That Targets the Golgi Complex in Clear Cell Renal Carcinoma Cells. Cancer Research. 71(1). 134–142. 16 indexed citations
14.
Beroukhim, Rameen, Arianna Di Napoli, Kirsten D. Mertz, et al.. (2009). Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney. Cancer Research. 69(11). 4674–4681. 310 indexed citations breakdown →
15.
Toro, Jorge R., G.M. Glenn, Michael Weinreich, et al.. (2008). BHD mutations, clinical and molecular genetic investigations of Birt–Hogg–Dubé syndrome: a new series of 50 families and a review of published reports. Journal of Medical Genetics. 45(6). 321–331. 333 indexed citations
16.
Toro, Jorge R., Stephen E. Pautler, Laveta Stewart, et al.. (2007). Lung Cysts, Spontaneous Pneumothorax, and Genetic Associations in 89 Families with Birt-Hogg-Dubé Syndrome. American Journal of Respiratory and Critical Care Medicine. 175(10). 1044–1053. 232 indexed citations
17.
Zhuang, Sen Hong, Robert W. Robey, Dan L. Sackett, et al.. (2007). Evidence for Microtubule Target Engagement in Tumors of Patients Receiving Ixabepilone. Clinical Cancer Research. 13(24). 7480–7486. 23 indexed citations
18.
Best, Carolyn J.M., John W. Gillespie, Yajun Yi, et al.. (2005). Molecular Alterations in Primary Prostate Cancer after Androgen Ablation Therapy. Clinical Cancer Research. 11(19). 6823–6834. 137 indexed citations
19.
Aprelikova, Olga, Gadisetti V.R. Chandramouli, Matthew J. A. Wood, et al.. (2004). Regulation of HIF prolyl hydroxylases by hypoxia‐inducible factors. Journal of Cellular Biochemistry. 92(3). 491–501. 173 indexed citations
20.
Rosenberg, Steven A., Michael T. Lotze, James Chih‐Hsin Yang, et al.. (1989). Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients. Annals of Surgery. 210(4). 474–485. 786 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Maria J. Merino Breakdown of academic impact, for papers by Angelo M. De Marzo Breakdown of academic impact, for papers by Razelle Kurzrock Breakdown of academic impact, for papers by Holger Moch Breakdown of academic impact, for papers by Carlos Cordon‐Cardo Breakdown of academic impact, for papers by David Sidransky Breakdown of academic impact, for papers by Paul Kleihues Breakdown of academic impact, for papers by Masaki Mori Breakdown of academic impact, for papers by Charles L. Sawyers Breakdown of academic impact, for papers by Martin Gleave
Rankless by CCL
2026