Jean J. Zhao

21.7k total citations · 9 hit papers
114 papers, 12.6k citations indexed

About

Jean J. Zhao is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Jean J. Zhao has authored 114 papers receiving a total of 12.6k indexed citations (citations by other indexed papers that have themselves been cited), including 76 papers in Molecular Biology, 44 papers in Oncology and 23 papers in Genetics. Recurrent topics in Jean J. Zhao's work include PI3K/AKT/mTOR signaling in cancer (41 papers), Chronic Lymphocytic Leukemia Research (16 papers) and Cancer-related Molecular Pathways (13 papers). Jean J. Zhao is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (41 papers), Chronic Lymphocytic Leukemia Research (16 papers) and Cancer-related Molecular Pathways (13 papers). Jean J. Zhao collaborates with scholars based in United States, China and United Kingdom. Jean J. Zhao's co-authors include Thomas M. Roberts, Hailing Cheng, Pixu Liu, Lauren M. Thorpe, Haluk Yuzugullu, Shom Goel, Sandra S. McAllister, Molly J. DeCristo, Johann S. Bergholz and Shaozhen Xie and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jean J. Zhao

112 papers receiving 12.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeting the phosphoinositide 3-kinase pathway in cancer

2009 2.2k citations Pixu Liu, Hailing Cheng et al. profile →
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting

2014 1.0k citations Lauren M. Thorpe, Haluk Yuzugullu et al. profile →
CDK4/6 inhibition triggers anti-tumour immunity

2017 998 citations Shaozhen Xie, Otto Metzger et al. profile →
Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis

2008 553 citations Shidong Jia, Pixu Liu et al. profile →
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer

2018 395 citations Carolynn E. Ohlson, Shaozhen Xie et al. profile →
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

2017 352 citations Jing Ni, Jean J. Zhao et al. profile →
CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest

2018 332 citations Jean J. Zhao et al. profile →
Targeting CDK4 and CDK6 in cancer

2022 281 citations Johann S. Bergholz, Jean J. Zhao et al. profile →
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

2022 163 citations Johann S. Bergholz, Sheheryar Kabraji et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jean J. Zhao United States	48	8.1k	4.1k	2.2k	1.8k	1.6k	114	12.6k
Lucia Ricci‐Vitiani Italy	48	5.4k 0.7×	4.8k 1.2×	1.3k 0.6×	2.9k 1.6×	1.6k 1.0×	145	10.6k
Xiu‐Wu Bian China	66	7.7k 1.0×	4.0k 1.0×	962 0.4×	4.2k 2.4×	1.3k 0.8×	278	12.8k
Fumiaki Tanaka Japan	68	9.2k 1.1×	2.9k 0.7×	812 0.4×	3.1k 1.8×	1.7k 1.1×	360	15.8k
Piotr Siciński United States	55	10.2k 1.3×	6.6k 1.6×	2.4k 1.1×	1.9k 1.1×	1.0k 0.7×	106	15.6k
David A. Frank United States	61	5.8k 0.7×	5.5k 1.3×	1.3k 0.6×	1.8k 1.0×	1.4k 0.9×	170	13.2k
Shih‐Hwa Chiou Taiwan	56	5.5k 0.7×	3.2k 0.8×	1.2k 0.5×	2.6k 1.4×	1.1k 0.7×	253	11.0k
Vivek Mittal United States	50	7.2k 0.9×	4.2k 1.0×	1.5k 0.7×	3.2k 1.8×	519 0.3×	130	12.9k
Kenneth J. Hillan United States	36	9.0k 1.1×	4.2k 1.0×	2.5k 1.1×	3.0k 1.7×	545 0.3×	57	14.6k
Dihua Yu United States	73	10.9k 1.4×	9.0k 2.2×	2.9k 1.3×	3.9k 2.2×	870 0.5×	242	19.0k
Suyun Huang United States	62	9.8k 1.2×	3.9k 1.0×	1.2k 0.5×	5.2k 2.9×	659 0.4×	99	13.7k

Countries citing papers authored by Jean J. Zhao

Since Specialization

Citations

This map shows the geographic impact of Jean J. Zhao's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean J. Zhao with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean J. Zhao more than expected).

Fields of papers citing papers by Jean J. Zhao

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean J. Zhao. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean J. Zhao. The network helps show where Jean J. Zhao may publish in the future.

Co-authorship network of co-authors of Jean J. Zhao

This figure shows the co-authorship network connecting the top 25 collaborators of Jean J. Zhao. A scholar is included among the top collaborators of Jean J. Zhao based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean J. Zhao. Jean J. Zhao is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Gaglia, Giorgio, Sheheryar Kabraji, Yang Dai, et al.. (2022). Temporal and spatial topography of cell proliferation in cancer. Nature Cell Biology. 24(3). 316–326. 31 indexed citations

Li, Yihang, Maria F. Pazyra‐Murphy, Daina Avizonis, et al.. (2021). Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN. The Journal of Cell Biology. 221(2). 62 indexed citations

Berghausen, Eva, Wiebke Janssen, Marius Vantler, et al.. (2021). Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents. Journal of Clinical Investigation. 131(19). 16 indexed citations

Pal, Sharmistha, David Kozono, Xiaodong Yang, et al.. (2018). Dual HDAC and PI3K Inhibition Abrogates NFκB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas. Cancer Research. 78(14). 4007–4021. 71 indexed citations

Zhou, Zhifen, Min Li, Lin Zhang, et al.. (2018). Oncogenic Kinase–Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem–like Cells. Cancer Research. 78(9). 2248–2261. 71 indexed citations

Thorpe, Lauren M., Jennifer M. Spangle, Carolynn E. Ohlson, et al.. (2017). PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α. Proceedings of the National Academy of Sciences. 114(27). 7095–7100. 81 indexed citations

Thorne, Natasha, Nasir Malik, Sonia Shah, et al.. (2016). High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress. Stem Cells Translational Medicine. 5(5). 613–627. 32 indexed citations

Cheng, Hailing, Carolynn E. Ohlson, Elaine Xu, et al.. (2015). PIK3CAH1047R- and Her2-initiated mammary tumors escape PI3K dependency by compensatory activation of MEK-ERK signaling. Oncogene. 35(23). 2961–2970. 32 indexed citations

Roy, Achira, Franck Kalume, Jing Ni, et al.. (2015). Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. eLife. 4. 77 indexed citations

10.

Gritsman, Kira, Haluk Yuzugullu, Thanh Von, et al.. (2014). Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α. Journal of Clinical Investigation. 124(4). 1794–1809. 46 indexed citations

11.

Cheng, Hailing, Pixu Liu, Fan Zhang, et al.. (2013). A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition. Cancer Research. 74(1). 15–23. 45 indexed citations

12.

Jia, Shidong, Xueliang Gao, Sang‐Hyun Lee, et al.. (2012). Opposing Effects of Androgen Deprivation and Targeted Therapy on Prostate Cancer Prevention. Cancer Discovery. 3(1). 44–51. 43 indexed citations

13.

Ni, Jing, Qingsong Liu, Shaozhen Xie, et al.. (2012). Functional Characterization of an Isoform-Selective Inhibitor of PI3K-p110β as a Potential Anticancer Agent. Cancer Discovery. 2(5). 425–433. 125 indexed citations

14.

Zhang, Qing, Ruiyang Tian, Qi Wang, et al.. (2011). Lysosomal Transmembrane Protein LAPTM4B Promotes Autophagy and Tolerance to Metabolic Stress in Cancer Cells. Cancer Research. 71(24). 7481–7489. 73 indexed citations

15.

Xu, Yong, Jennifer W. Hill, Makoto Fukuda, et al.. (2010). PI3K Signaling in the Ventromedial Hypothalamic Nucleus Is Required for Normal Energy Homeostasis. Cell Metabolism. 12(1). 88–95. 91 indexed citations

16.

Hill, Jennifer W., Yong Xu, Frédéric Preitner, et al.. (2009). Phosphatidyl Inositol 3-Kinase Signaling in Hypothalamic Proopiomelanocortin Neurons Contributes to the Regulation of Glucose Homeostasis. Endocrinology. 150(11). 4874–4882. 75 indexed citations

17.

Gjoerup, Ole, Jiaping Wu, Devin Chandler-Militello, et al.. (2007). Surveillance mechanism linking Bub1 loss to the p53 pathway. Proceedings of the National Academy of Sciences. 104(20). 8334–8339. 46 indexed citations

18.

Zhao, Jean J., Zhenning Liu, Lı Wang, et al.. (2005). The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells. Proceedings of the National Academy of Sciences. 102(51). 18443–18448. 267 indexed citations

19.

Berger, Raanan, Phillip G. Febbo, Pradip K. Majumder, et al.. (2004). Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells. Cancer Research. 64(24). 8867–8875. 140 indexed citations

20.

Zhao, Jean J., Thomas M. Roberts, & William C. Hahn. (2004). Functional genetics and experimental models of human cancer. Trends in Molecular Medicine. 10(7). 344–350. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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