Roddy S. O’Connor

11.6k citations

54 papers · 5.8k indexed · 4 hit papers · h-index 25

Co-authors: Michael C. Milone Carl H. June Omkar U. Kawalekar Saba Ghassemi Nathaniel W. Snyder Grace K. Pavlath John Scholler Joseph A. Fraietta
Topics: CAR-T cell therapy research (37 papers)Immune Cell Function and Interaction (18 papers)Viral Infectious Diseases and Gene Expression in Insects (13 papers)
Cited by: Oncology Immunology Genetics
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: United States Iran United Kingdom

In The Last Decade

Roddy S. O’Connor

54 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CAR T cell immunotherapy for human cancer

2018 2.1k citations Carl H. June, Roddy S. O’Connor et al. profile →
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

2016 887 citations Omkar U. Kawalekar, Roddy S. O’Connor et al. Immunity profile →
CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

2021 243 citations Alba Rodríguez-García, Rachel C. Lynn et al. Nature Communications profile →
Rapid manufacturing of non-activated potent CAR T cells

2022 184 citations Saba Ghassemi, Joseph S. Durgin et al. profile →

Peers

Countries citing papers authored by Roddy S. O’Connor

Since Specialization

Citations

This map shows the geographic impact of Roddy S. O’Connor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roddy S. O’Connor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roddy S. O’Connor more than expected).

Fields of papers citing papers by Roddy S. O’Connor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roddy S. O’Connor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roddy S. O’Connor. The network helps show where Roddy S. O’Connor may publish in the future.

Co-authorship network of co-authors of Roddy S. O’Connor

This figure shows the co-authorship network connecting the top 25 collaborators of Roddy S. O’Connor. A scholar is included among the top collaborators of Roddy S. O’Connor based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roddy S. O’Connor. Roddy S. O’Connor is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Deletion of CD38 enhances CD19 chimeric antigen receptor T cell function 2024 ·SHILAP Revista de lepidopterología ·Kimberly Veliz,Feng Shen,Olga Shestova,Maksim Shestov,Alexander A. Shestov,(unknown),Tyler Hansen,Roddy S. O’Connor,Saar Gill	6
2	Current Status and Challenges of Vaccination Therapy for Glioblastoma 2023 ·Molecular Cancer Therapeutics ·(unknown),(unknown),Ammar Ebrahimi,Roddy S. O’Connor	15
3	Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function 2023 ·Cancer Immunology Research ·(unknown),(unknown),Yansen Xiao,Omar Johnson,(unknown),Roddy S. O’Connor,Meizan Lai,Hong Kong,(unknown),Victoria Tai,(unknown),Matthew Holmes,James L. Riley,Carl H. June,Neil C. Sheppard	16
4	Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy 2023 ·Blood ·Yan Tang,Wei Liu,(unknown),Omar Johnson,Zainul S. Hasanali,(unknown),Alexander A. Shestov,Raymone Pajarillo,(unknown),Matthew Holmes,Liping Wang,Natalie Shih,Roddy S. O’Connor,Marco Ruella,Alfred L. Garfall,David Allman,Dan T. Vogl,Adam D. Cohen,Carl H. June,Neil C. Sheppard	9
5	Checkmate: Metabolic flexibility with a STING in its tail 2023 ·Science Advances ·Roddy S. O’Connor	3
6	Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase 2021 ·Molecular Therapy ·Joseph S. Durgin,Radhika Thokala,Lexus R. Johnson,(unknown),John Leferovich,Vijay Bhoj,Saba Ghassemi,Michael C. Milone,Zev A. Binder,Donald M. O’Rourke,Roddy S. O’Connor	21
7	CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapybreakdown → 2021 ·Nature Communications ·Alba Rodríguez-García,Rachel C. Lynn,Mathilde Poussin,Monika A. Eiva,Lauren Shaw,Roddy S. O’Connor,Nicholas G. Minutolo,Victoria Casado‐Medrano,Gonzalo López,Takami Matsuyama,Daniel J. Powell	243
8	Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma 2021 ·Frontiers in Oncology ·Joseph S. Durgin,Fraser Henderson,MacLean P. Nasrallah,Suyash Mohan,Sumei Wang,Simon F. Lacey,J. Joseph Melenhorst,Arati Desai,John Y. K. Lee,Marcela V. Maus,Carl H. June,Steven Brem,Roddy S. O’Connor,Zev A. Binder,Donald M. O’Rourke	54
9	Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy 2020 ·Clinical Cancer Research ·Eduardo Huarte,Roddy S. O’Connor,Michael T. Peel,Selene Nuñez-Cruz,John Leferovich,Ashish Juvekar,(unknown),Lisa Truong,Taisheng Huang,Ahmad Naim,Michael C. Milone,Paul Smith	67
10	Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues 2020 ·Open Biology ·Erika L. Varner,Sophie Trefely,David Bartee,(unknown),Luke Izzo,(unknown),Roddy S. O’Connor,Erin L. Seifert,Kathryn E. Wellen,Jordan L. Meier,Nathaniel W. Snyder	100
11	Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design 2020 ·Molecular Therapy — Methods & Clinical Development ·Saba Ghassemi,Francisco J. Martinez-Becerra,Аlyssa M. Master,Sarah A. Richman,(unknown),John Leferovich,(unknown),Juan Carlos García‐Cañaveras,(unknown),(unknown),(unknown),Joshua D. Rabinowitz,Michael C. Milone,Carl H. June,Roddy S. O’Connor	52
12	Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells 2019 ·Methods in molecular biology ·Roddy S. O’Connor,Michael C. Milone	2
13	Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene 2019 ·Molecular Therapy ·Mark A. Sellmyer,Sarah A. Richman,(unknown),Catherine Hou,Chi-Chang Weng,Robert H. Mach,Roddy S. O’Connor,Michael C. Milone,Michael D. Farwell	76
14	Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells 2018 ·Cancer Immunology Research ·Saba Ghassemi,Selene Nuñez-Cruz,Roddy S. O’Connor,Joseph A. Fraietta,Prachi Patel,John Scholler,David M. Barrett,Stefan Lundh,Megan M. Davis,Felipe Bedoya,Changfeng Zhang,John Leferovich,Simon F. Lacey,Bruce L. Levine,Stephan A. Grupp,Carl H. June,J. Joseph Melenhorst,Michael C. Milone	212
15	The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations 2018 ·Scientific Reports ·Roddy S. O’Connor,Lili Guo,Saba Ghassemi,Nathaniel W. Snyder,Andrew J. Worth,Liwei Weng,Yoonseok Kam,Benjamin Philipson,Sophie Trefely,Selene Nuñez-Cruz,Ian A. Blair,Carl H. June,Michael C. Milone	126
16	In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines 2017 ·American Journal of Transplantation ·Keli L. Hippen,Roddy S. O’Connor,(unknown),Asim Saha,Eric A. Hanse,(unknown),Sarah C. Merkel,Ameeta Kelekar,James L. Riley,Bruce L. Levine,Carl H. June,Laurence A. Turka,Leslie S. Kean,Margaret L. MacMillan,Jeffrey S. Miller,Jasenka Wagner,David H. Munn,Bruce R. Blazar	24
17	Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cellsbreakdown → 2016 ·Immunity ·Omkar U. Kawalekar,Roddy S. O’Connor,Joseph A. Fraietta,Lili Guo,Shannon E. McGettigan,Avery D. Posey,Prachi Patel,Sònia Guedan,John Scholler,Brian Keith,Nathaniel W. Snyder,Ian A. Blair,Michael C. Milone,Carl H. June	887
18	Substrate rigidity regulates human T cell activation and proliferation (52.9) 2012 ·The Journal of Immunology ·Roddy S. O’Connor,Xueli Hao,K. Robert Shen,(unknown),Lance C. Kam,Michael C. Milone	1
19	Genomic and Clinical Analysis of Amplification of the 13q31 Chromosomal Region in Alveolar Rhabdomyosarcoma: A Report from the Children's Oncology Group 2011 ·Clinical Cancer Research ·(unknown),Fenghai Duan,Lynette M. Smith,(unknown),Roddy S. O’Connor,Chune Zhang,(unknown),Julie M. Gastier‐Foster,Frederic G. Barr	50
20	Sca-1 negatively regulates proliferation and differentiation of muscle cells 2005 ·Developmental Biology ·Patrick O. Mitchell,(unknown),Roddy S. O’Connor,Timothy A. Graubert,Elaine Dzierzak,Grace K. Pavlath	85

About Roddy S. O’Connor

Roddy S. O’Connor is a scholar working on Oncology, Immunology and Biological Psychiatry, having authored 54 papers that have together received 5.8k indexed citations. Recurring topics across this work include CAR-T cell therapy research (37 papers), Immune Cell Function and Interaction (18 papers) and Viral Infectious Diseases and Gene Expression in Insects (13 papers). The work is most often cited by research in Oncology (3.7k citations), Immunology (2.4k citations) and Genetics (887 citations). Roddy S. O’Connor has collaborated with scholars based in United States, Iran and United Kingdom. Frequent co-authors include Michael C. Milone, Carl H. June, Omkar U. Kawalekar, Saba Ghassemi, Nathaniel W. Snyder, Grace K. Pavlath, John Scholler, Joseph A. Fraietta, Prachi Patel and Ian A. Blair. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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