Michael C. Milone

23.4k citations

136 papers · 15.6k indexed · 11 hit papers · h-index 46

Impact in

Oncology top 0.05%
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
Immunology top 0.2%
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology

Papers in

Oncology 83
- CAR-T cell therapy research 81
Immunology 45
- Immune Cell Function and Interaction 28
- T-cell and B-cell Immunology 16
- Immunotherapy and Immune Responses 14

Co-authors: Carl H. June Roddy S. O’Connor Omkar U. Kawalekar Saba Ghassemi Stephan A. Grupp Bruce L. Levine Una O’Doherty Anne Chew
Journals: Blood (18 papers)Molecular Therapy (9 papers)The Journal of Immunology (7 papers)Clinical Cancer Research (4 papers)Cancer Immunology Research (4 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Michael C. Milone

134 papers receiving 15.4k citations

Hit Papers

11 papers align trajectories log scale

Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells 2023 · 107 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature Biotechnology
2022 Nature Biomedical Engineering
2019 American Journal of Hematology
2018 Science
2018 Leukemia
2016 Immunity
2016 Science
2015 Science Translational Medicine
2013 New England Journal of Medicine
2009 Proceedings of the National Academy of Sciences
2009 Molecular Therapy

Peers

Countries citing papers authored by Michael C. Milone

Since Specialization

Citations

This map shows the geographic impact of Michael C. Milone's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael C. Milone with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael C. Milone more than expected).

Fields of papers citing papers by Michael C. Milone

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael C. Milone. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael C. Milone. The network helps show where Michael C. Milone may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael C. Milone, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael C. Milone Line = papers co-authored together Michael C. Milone links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Performance of a Xylazine Test Strip in Urine Biospecimens Journal of Addiction Medicine ·Daisy Unsihuay, Ping Wang, Michael C. Milone, Ashish P. Thakrar, Jeanmarie Perrone	2025	1
2	CD38 as a pan-hematologic target for chimeric antigen receptor T cells Blood Advances ·Cai Shang-shu, Caroline Diorio, Donghua Huo, Kimberly Veliz, Olga Shestova, Feng Shen, Selene Nuñez-Cruz, Tiffaney L. Vincent, Fei Miao, Michael C. Milone, Carl H. June, David T. Teachey, Sarah K. Tasian, Richard Aplenc, Saar Gill	2023	33
3	Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells Nature Biotechnology ·Sangwook Oh, Xuming Mao, Sílvio M. Vieira, Jinmin Lee, Silvia Juliana Pacheco, Eun Jung Choi, Muhammadul Bakir Yaakob, Rebekah Kennedy, Damián Maseda, Patricia Tsao, Christoph T. Ellebrecht, Sami Khella, David P. Richman, Kevin C. O’Connor, Uri Herzberg, Gwendolyn K. Binder, Michael C. Milone, Samik Basu, Aimee Payne Hit paper breakdown →	2023	107
4	Association of Urine Fentanyl Concentration With Severity of Opioid Withdrawal Among Patients Presenting to the Emergency Department Journal of Addiction Medicine ·Ashish P. Thakrar, LIU Zhimin Ding Yang, Jeanmarie Perrone, Michael C. Milone, Margaret Lowenstein, Christopher K. Snider, Anthony Spadaro, M. Kit Delgado, Lewis S. Nelson, Austin S. Kilaru	2023	8
5	Generation of non-human primate CAR Tregs using artificial antigen-presenting cells, simian tropic lentiviral vectors, and antigen-specific restimulation STAR Protocols ·Gavin I. Ellis, Rosângela Saldanha Pereira, Lujuan Cai, Celi Maribel Herrera Altafulla, D. V. Klushin, Vijay Bhoj, Michael C. Milone, Raimon Duran‐Struuck, James L. Riley	2022	2
6	Trafficking and persistence of alloantigen-specific chimeric antigen receptor regulatory T cells in Cynomolgus macaque Cell Reports Medicine ·Gavin I. Ellis, Celi Maribel Herrera Altafulla, Lujuan Cai, Rosângela Saldanha Pereira, D. V. Klushin, Vijay Bhoj, Michael C. Milone, Wei Wang, Chengyang Liu, Ali Naji, Raimon Duran‐Struuck, James L. Riley	2022	19
7	The Safety of Bridging Radiation with Anti-BCMA CAR T-Cell Therapy for Multiple Myeloma Clinical Cancer Research ·Hamlin Jennafer A. P., Adam D. Cohen, Simon F. Lacey, Megan M. Davis, Alfred L. Garfall, J. Joseph Melenhorst, Russell Maxwell, W. Tristram Arscott, Amit Maity, Joshua Jones, John P. Plastaras, Edward A. Stadtmauer, Bruce L. Levine, Carl H. June, Michael C. Milone, Ima Paydar	2021	23
8	Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase Molecular Therapy ·Joseph S. Durgin, Radhika Thokala, Lexus R. Johnson, Bambang Haryo Prihatmanto, John Leferovich, Vijay Bhoj, Saba Ghassemi, Michael C. Milone, Zev A. Binder, Donald M. O’Rourke, Roddy S. O’Connor	2021	21
9	Engineering-enhanced CAR T cells for improved cancer therapy Nature Cancer ·Michael C. Milone, Jie Xu, Sai‐Juan Chen, McKensie Collins, Jianfeng Zhou, Daniel J. Powell, J. Joseph Melenhorst	2021	95
10	Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy Clinical Cancer Research ·Eduardo Huarte, Roddy S. O’Connor, Michael T. Peel, Selene Nuñez-Cruz, John Leferovich, Ashish Juvekar, A Ortiz, Lisa Truong, Taisheng Huang, Ahmad Naim, Michael C. Milone, Paul Smith	2020	67
11	Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo Molecular Therapy ·Sarah A. Richman, Liang-Chuan Wang, Edmund K. Moon, Uday R. Khire, Steven Μ. Albelda, Michael C. Milone	2020	69
12	Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells Cancer Immunology Research ·Saba Ghassemi, Selene Nuñez-Cruz, Roddy S. O’Connor, Joseph A. Fraietta, Prachi Patel, John Scholler, David M. Barrett, Stefan Lundh, Megan M. Davis, Felipe Bedoya, Changfeng Zhang, John Leferovich, Simon F. Lacey, Bruce L. Levine, Stephan A. Grupp, Carl H. June, J. Joseph Melenhorst, Michael C. Milone	2018	212
13	High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model Cancer Immunology Research ·Sarah A. Richman, Selene Nuñez-Cruz, Babak Moghimi, Lucy Z. Li, Zachary T. Gershenson, Zissimos P. Mourelatos, David M. Barrett, Stephan A. Grupp, Michael C. Milone	2017	202
14	Studying Immunoreceptor Signaling in Human T Cells Using Electroporation of In Vitro Transcribed mRNA Methods in molecular biology ·Omkar U. Kawalekar, Carl H. June, Michael C. Milone	2017	1
15	The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma Clinical Cancer Research ·Marco Ruella, Saad S. Kenderian, Olga Shestova, Joseph A. Fraietta, Sohail Qayyum, Qian Zhang, Marcela V. Maus, Xiaobin Liu, Selene Nuñez-Cruz, Michael Klichinsky, Omkar U. Kawalekar, Michael C. Milone, Simon F. Lacey, Anthony R. Mato, Stephen J. Schuster, Michael Kalos, Carl H. June, Saar Gill, Mariusz A. Wasik	2016	141
16	Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease Science ·Christoph T. Ellebrecht, Vijay Bhoj, Arben Nace, Eun Jung Choi, Xuming Mao, Michael Jeffrey Cho, Giovanni Di Zenzo, Antonio Lanzavecchia, John T. Seykora, George Cotsarelis, Michael C. Milone, Aimee Payne Hit paper breakdown →	2016	512
17	Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors Cancer Immunology Research ·Enxiu Wang, Liang-Chuan Wang, Ching‐Yi Tsai, Vijay Bhoj, Evan W. Roberts, Edmund K. Moon, Kheng Newick, Jing Sun, Albert Lo, Timothy Baradet, Michael D. Feldman, David M. Barrett, Ellen Puré, Steven Albelda, Michael C. Milone	2015	91
18	Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells Cancer Immunology Research ·Matthew J. Frigault, Ji‐Hyun Lee, Maria C. Basil, Carmine Carpenito, Shinichiro Motohashi, John Scholler, Omkar U. Kawalekar, Sònia Guedan, Shannon E. McGettigan, Avery D. Posey, Sonny Ang, Laurence J.N. Cooper, Jesse M. Platt, F. Brad Johnson, Chrystal M. Paulos, Yangbing Zhao, Michael Kalos, Michael C. Milone, Carl H. June	2015	233
19	Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors Clinical Cancer Research ·Edmund K. Moon, Liang-Chuan Wang, Douglas V. Dolfi, Caleph B. Wilson, Raghuveer Ranganathan, Jing Sun, Veena Kapoor, John Scholler, Ellen Puré, Michael C. Milone, Carl H. June, James L. Riley, E. John Wherry, Steven Μ. Albelda	2014	344
20	Substrate rigidity regulates human T cell activation and proliferation (52.9) The Journal of Immunology ·Roddy S. O’Connor, Xueli Hao, K. Robert Shen, Adam Kłak, Lance C. Kam, Michael C. Milone	2012	1

About Michael C. Milone

Michael C. Milone is a scholar working on Oncology, Immunology, Transplantation, Toxicology and Biotechnology, having authored 136 papers that have together received 15.6k indexed citations. Recurring topics across this work include CAR-T cell therapy research (81 papers), Immune Cell Function and Interaction (28 papers), Virus-based gene therapy research (21 papers), Viral Infectious Diseases and Gene Expression in Insects (18 papers), T-cell and B-cell Immunology (16 papers), Nanowire Synthesis and Applications (15 papers), Immunotherapy and Immune Responses (14 papers) and CRISPR and Genetic Engineering (8 papers). The work is most often cited by research in Oncology (11.5k citations), Immunology (5.8k citations), Genetics (3.5k citations), Biomedical Engineering (3.6k citations) and Hematology (791 citations). Michael C. Milone has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Carl H. June, Roddy S. O’Connor, Omkar U. Kawalekar, Saba Ghassemi, Stephan A. Grupp, Bruce L. Levine, Una O’Doherty, Anne Chew, David T. Teachey and David M. Barrett. Their work appears in journals such as Blood, Molecular Therapy, The Journal of Immunology, Clinical Cancer Research and Cancer Immunology Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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