Kathryn E. Wellen

22.9k total citations · 6 hit papers
80 papers, 14.2k citations indexed

About

Kathryn E. Wellen is a scholar working on Molecular Biology, Cancer Research and Physiology. According to data from OpenAlex, Kathryn E. Wellen has authored 80 papers receiving a total of 14.2k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 39 papers in Cancer Research and 21 papers in Physiology. Recurrent topics in Kathryn E. Wellen's work include Cancer, Hypoxia, and Metabolism (33 papers), Epigenetics and DNA Methylation (20 papers) and RNA modifications and cancer (17 papers). Kathryn E. Wellen is often cited by papers focused on Cancer, Hypoxia, and Metabolism (33 papers), Epigenetics and DNA Methylation (20 papers) and RNA modifications and cancer (17 papers). Kathryn E. Wellen collaborates with scholars based in United States, Slovakia and Canada. Kathryn E. Wellen's co-authors include Gökhan S. Hotamışlıgil, Craig B. Thompson, Justin R. Cross, Uma M. Sachdeva, Thi Bui, Georgia Hatzivassiliou, Nathaniel W. Snyder, Steven Zhao, Sophie Trefely and Alessandro Carrer and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Kathryn E. Wellen

75 papers receiving 14.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inflammation, stress, and diabetes

2005 3.1k citations Kathryn E. Wellen, Gökhan S. Hotamışlıgil Journal of Clinical Investigation profile →
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

2009 1.7k citations Kathryn E. Wellen, Georgia Hatzivassiliou et al. Science profile →
IDH mutation impairs histone demethylation and results in a block to cell differentiation

2012 1.5k citations Kathryn E. Wellen, Craig B. Thompson et al. profile →
Inflammation, stress, and diabetes

2005 969 citations Kathryn E. Wellen Journal of Clinical Investigation profile →
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

2020 388 citations Steven Zhao, Kahealani Uehara et al. profile →
Acetyl-CoA metabolism in cancer

2023 161 citations David A. Guertin, Kathryn E. Wellen profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kathryn E. Wellen United States	40	8.3k	3.9k	2.9k	2.8k	1.6k	80	14.2k
Zoltàn Arany United States	61	9.0k 1.1×	3.1k 0.8×	4.7k 1.6×	1.7k 0.6×	1.1k 0.7×	174	16.1k
Dao Wen Wang China	73	9.5k 1.2×	3.0k 0.8×	1.7k 0.6×	1.8k 0.6×	1.3k 0.8×	605	21.3k
Athanasios G. Papavassiliou Greece	68	8.0k 1.0×	2.7k 0.7×	1.4k 0.5×	1.8k 0.6×	1.6k 1.0×	488	17.5k
Yatrik M. Shah United States	57	5.1k 0.6×	2.8k 0.7×	1.2k 0.4×	1.5k 0.5×	1.1k 0.7×	171	10.4k
Lluís Fajas France	49	8.0k 1.0×	2.2k 0.6×	3.2k 1.1×	1.9k 0.7×	887 0.6×	115	11.3k
Thomas Kietzmann Germany	50	5.7k 0.7×	3.4k 0.9×	1.7k 0.6×	1.3k 0.5×	1.1k 0.7×	177	10.9k
Yujie Li China	30	8.5k 1.0×	1.8k 0.5×	1.8k 0.6×	7.7k 2.7×	1.3k 0.8×	166	16.5k
Rama Natarajan United States	79	10.0k 1.2×	4.2k 1.1×	2.2k 0.8×	1.6k 0.6×	2.4k 1.5×	246	18.5k
Marten H. Hofker Netherlands	68	7.1k 0.9×	1.7k 0.4×	2.0k 0.7×	3.3k 1.2×	2.3k 1.5×	203	15.2k
Maria Febbraio United States	71	9.2k 1.1×	2.5k 0.6×	2.9k 1.0×	3.6k 1.3×	5.5k 3.5×	170	19.0k

Countries citing papers authored by Kathryn E. Wellen

Since Specialization

Citations

This map shows the geographic impact of Kathryn E. Wellen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kathryn E. Wellen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kathryn E. Wellen more than expected).

Fields of papers citing papers by Kathryn E. Wellen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kathryn E. Wellen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kathryn E. Wellen. The network helps show where Kathryn E. Wellen may publish in the future.

Co-authorship network of co-authors of Kathryn E. Wellen

This figure shows the co-authorship network connecting the top 25 collaborators of Kathryn E. Wellen. A scholar is included among the top collaborators of Kathryn E. Wellen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kathryn E. Wellen. Kathryn E. Wellen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Cottam, Matthew A., Hanbing An, Brian D. Lehmann, et al.. (2025). Comparison of Lean, Obese, and Weight-Loss Models Reveals TREM2 Deficiency Attenuates Breast Cancer Growth Uniquely in Lean Mice and Alters Clonal T-cell Populations. Cancer Research. 85(7). 1219–1235.

Silva-Diz, Victoria da, Maya Aleksandrova, Oekyung Kim, et al.. (2025). A feedforward loop between ACLY and MYC supports T-ALL progression in vivo. PubMed. 2(2). 100069–100069. 1 indexed citations

Lazaropoulos, Michael P., Andrew Gibb, Douglas J. Chapski, et al.. (2024). Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program. Nature Cardiovascular Research. 3(7). 869–882. 11 indexed citations

Vostrejs, William P., Sydney L. Campbell, Samantha B. Kemp, et al.. (2024). N-glycosylation by Mgat5 imposes a targetable constraint on immune-mediated tumor clearance. JCI Insight. 9(12). 3 indexed citations

Supplee, Julianna, Hayley C. Affronti, Rebekah Brooks, et al.. (2024). ACLY alternative splicing correlates with cancer phenotypes. Journal of Biological Chemistry. 300(7). 107418–107418. 3 indexed citations

Andrieu, Guillaume P., Guillaume Hypolite, Caroline Costa, et al.. (2024). ATP citrate lyase is an essential player in the metabolic rewiring induced by PTEN loss during T-ALL development. Blood Advances. 9(7). 1670–1691.

Mukhi, Dhanunjay, Lingzhi Li, Hongbo Liu, et al.. (2023). ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules. Journal of Clinical Investigation. 134(4). 22 indexed citations

Ramsey, Haley E., Phuong Nguyen, Andrew R. Patterson, et al.. (2022). Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic–Epigenetic Cross-Talk. ImmunoHorizons. 6(12). 837–850. 3 indexed citations

Rolland, Delphine, Özlem Önder, Venkatesha Basrur, et al.. (2020). FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells. Cancer Research. 80(12). 2498–2511. 22 indexed citations

10.

Varner, Erika L., Sophie Trefely, David Bartee, et al.. (2020). Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues. Open Biology. 10(9). 200187–200187. 100 indexed citations

11.

Calejman, Camila Martínez, Sophie Trefely, Amelia K. Luciano, et al.. (2020). mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nature Communications. 11(1). 575–575. 106 indexed citations

12.

Trefely, Sophie, Claudia D. Lovell, Nathaniel W. Snyder, & Kathryn E. Wellen. (2020). Compartmentalised acyl-CoA metabolism and roles in chromatin regulation. Molecular Metabolism. 38. 100941–100941. 180 indexed citations

13.

Carrer, Alessandro, Sophie Trefely, Steven Zhao, et al.. (2019). Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer Discovery. 9(3). 416–435. 227 indexed citations

14.

Wellen, Kathryn E. & Nathaniel W. Snyder. (2019). Should we consider subcellular compartmentalization of metabolites, and if so, how do we measure them?. Current Opinion in Clinical Nutrition & Metabolic Care. 22(5). 347–354. 36 indexed citations

15.

Liu, Xiaojing, Daniel E. Cooper, Ahmad A. Cluntun, et al.. (2018). Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals. Cell. 175(2). 502–513.e13. 283 indexed citations

16.

Carrer, Alessandro, Joshua L.D. Parris, Sophie Trefely, et al.. (2017). Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels. Journal of Biological Chemistry. 292(8). 3312–3322. 124 indexed citations

17.

Bloomer, Steven A., Kathryn E. Wellen, & Gregory C. Henderson. (2017). Sexual dimorphism in the hepatic protein response to a moderate trans fat diet in senescence-accelerated mice. Lipids in Health and Disease. 16(1). 243–243. 6 indexed citations

18.

Wellen, Kathryn E. & Craig B. Thompson. (2010). Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess. Molecular Cell. 40(2). 323–332. 362 indexed citations

19.

Wellen, Kathryn E., Georgia Hatzivassiliou, Uma M. Sachdeva, et al.. (2009). ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation. Science. 324(5930). 1076–1080. 1698 indexed citations breakdown →

20.

Wellen, Kathryn E., Raquel Fucho, Margaret F. Gregor, et al.. (2007). Coordinated Regulation of Nutrient and Inflammatory Responses by STAMP2 Is Essential for Metabolic Homeostasis. Cell. 129(3). 537–548. 179 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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