Sophie Trefely

4.7k total citations · 1 hit paper
38 papers, 3.2k citations indexed

About

Sophie Trefely is a scholar working on Molecular Biology, Physiology and Cancer Research. According to data from OpenAlex, Sophie Trefely has authored 38 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 13 papers in Physiology and 9 papers in Cancer Research. Recurrent topics in Sophie Trefely's work include RNA modifications and cancer (9 papers), Cancer, Hypoxia, and Metabolism (8 papers) and Metabolism and Genetic Disorders (8 papers). Sophie Trefely is often cited by papers focused on RNA modifications and cancer (9 papers), Cancer, Hypoxia, and Metabolism (8 papers) and Metabolism and Genetic Disorders (8 papers). Sophie Trefely collaborates with scholars based in United States, Australia and United Kingdom. Sophie Trefely's co-authors include Nathaniel W. Snyder, Kathryn E. Wellen, Alessandro Carrer, Steven Zhao, Roddy S. O’Connor, Claudia D. Lovell, Sydney L. Campbell, Kathleen Graham, Gregory L. Beatty and AnnMarie Torres and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Sophie Trefely

38 papers receiving 3.2k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

2020 388 citations Steven Zhao, Cholsoon Jang et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sophie Trefely United States	26	2.0k	825	769	561	416	38	3.2k
Raphael J. Morscher Austria	13	1.8k 0.9×	899 1.1×	895 1.2×	421 0.8×	230 0.6×	16	3.1k
Lei Jiang China	24	1.8k 0.9×	1.1k 1.4×	800 1.0×	527 0.9×	172 0.4×	68	3.1k
Simon‐Pierre Gravel Canada	21	2.0k 1.0×	764 0.9×	419 0.5×	389 0.7×	412 1.0×	32	2.9k
Keishi Miyata Japan	32	1.4k 0.7×	1.0k 1.2×	439 0.6×	550 1.0×	317 0.8×	85	3.4k
Toshiya Tanaka Japan	32	2.4k 1.2×	548 0.7×	677 0.9×	523 0.9×	395 0.9×	84	3.9k
Jianxin Xie China	22	3.0k 1.5×	1.2k 1.5×	608 0.8×	409 0.7×	483 1.2×	40	4.1k
Gerta Hoxhaj United States	18	2.7k 1.3×	878 1.1×	408 0.5×	383 0.7×	329 0.8×	24	3.7k
Franck Peiretti France	31	1.5k 0.7×	587 0.7×	657 0.9×	840 1.5×	604 1.5×	82	3.6k
Miguel A. Gijón United States	27	1.9k 1.0×	822 1.0×	402 0.5×	256 0.5×	517 1.2×	42	3.3k
Steven Zhao United States	11	1.3k 0.7×	720 0.9×	379 0.5×	382 0.7×	231 0.6×	17	2.1k

Countries citing papers authored by Sophie Trefely

Since Specialization

Citations

This map shows the geographic impact of Sophie Trefely's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sophie Trefely with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sophie Trefely more than expected).

Fields of papers citing papers by Sophie Trefely

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sophie Trefely. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sophie Trefely. The network helps show where Sophie Trefely may publish in the future.

Co-authorship network of co-authors of Sophie Trefely

This figure shows the co-authorship network connecting the top 25 collaborators of Sophie Trefely. A scholar is included among the top collaborators of Sophie Trefely based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sophie Trefely. Sophie Trefely is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Trefely, Sophie, et al.. (2024). Acetate to the rescue: Acetyl-CoA facilitates placental development. Cell stem cell. 31(9). 1241–1243. 1 indexed citations

2.

Soaita, Ioana, Emily Megill, Zoltàn Arany, et al.. (2023). Dynamic protein deacetylation is a limited carbon source for acetyl-CoA–dependent metabolism. Journal of Biological Chemistry. 299(6). 104772–104772. 11 indexed citations

3.

Ciraku, Lorela, Zachary A. Bacigalupa, Jing Ju, et al.. (2022). O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation. Oncogene. 41(14). 2122–2136. 42 indexed citations

4.

Doan, Mary T., Michael D. Neinast, Erika L. Varner, et al.. (2022). Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species. Journal of Lipid Research. 63(6). 100224–100224. 1 indexed citations

5.

Varner, Erika L., Sophie Trefely, David Bartee, et al.. (2020). Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues. Open Biology. 10(9). 200187–200187. 100 indexed citations

6.

Trefely, Sophie, Claudia D. Lovell, Nathaniel W. Snyder, & Kathryn E. Wellen. (2020). Compartmentalised acyl-CoA metabolism and roles in chromatin regulation. Molecular Metabolism. 38. 100941–100941. 180 indexed citations

7.

Calejman, Camila Martínez, Sophie Trefely, Amelia K. Luciano, et al.. (2020). mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nature Communications. 11(1). 575–575. 106 indexed citations

8.

Yu, Xiang, Matthew R. Willmann, Lee E. Vandivier, et al.. (2020). Messenger RNA 5′ NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis. Developmental Cell. 56(1). 125–140.e6. 50 indexed citations

9.

Zhao, Steven, Cholsoon Jang, Joyce Liu, et al.. (2020). Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 579(7800). 586–591. 388 indexed citations breakdown →

10.

Carrer, Alessandro, Sophie Trefely, Steven Zhao, et al.. (2019). Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer Discovery. 9(3). 416–435. 227 indexed citations

11.

Trefely, Sophie, Joyce Liu, Katharina Huber, et al.. (2019). Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism. Molecular Metabolism. 30. 61–71. 20 indexed citations

12.

Fernandez, Sully, John M. Viola, AnnMarie Torres, et al.. (2019). Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Reports. 27(9). 2772–2784.e6. 60 indexed citations

13.

Liu, Mingen, Roddy S. O’Connor, Sophie Trefely, et al.. (2019). Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal. Nature Immunology. 20(3). 265–275. 229 indexed citations

14.

Fernandez, Sully, John M. Viola, AnnMarie Torres, et al.. (2018). Adipocyte ACLY Facilitates Dietary Carbohydrate Handling and Protects Against Insulin Resistance in Females. SSRN Electronic Journal. 1 indexed citations

15.

Carrer, Alessandro, Joshua L.D. Parris, Sophie Trefely, et al.. (2017). Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels. Journal of Biological Chemistry. 292(8). 3312–3322. 124 indexed citations

16.

Frey, Alexander J., Daniel R. Feldman, Sophie Trefely, et al.. (2016). LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and 13C-isotopic labeling of acyl-coenzyme A thioesters. Analytical and Bioanalytical Chemistry. 408(13). 3651–3658. 59 indexed citations

17.

Trefely, Sophie, et al.. (2016). FluxFix: automatic isotopologue normalization for metabolic tracer analysis. BMC Bioinformatics. 17(1). 485–485. 60 indexed citations

18.

Hoffman, Nolan J., Benjamin L. Parker, Rima Chaudhuri, et al.. (2015). Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. Cell Metabolism. 22(5). 922–935. 320 indexed citations

19.

Trefely, Sophie, James R. Krycer, Rima Chaudhuri, et al.. (2015). Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway. Journal of Biological Chemistry. 290(43). 25834–25846. 46 indexed citations

20.

Hoffman, Nolan J., Benjamin L. Parker, Rima Chaudhuri, et al.. (2015). Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. Cell Metabolism. 22(5). 948–948. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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