Bruce L. Levine

66.3k citations

255 papers · 32.7k indexed · 16 hit papers · h-index 76

Impact in

Oncology top 0.01%
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
Immunology top 0.05%
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology

Papers in

Oncology 162
- CAR-T cell therapy research 150
Immunology 105
- Immune Cell Function and Interaction 65
- T-cell and B-cell Immunology 48
- Immunotherapy and Immune Responses 47

Co-authors: Carl H. June David L. Porter Michael Kalos Adam Bagg Stephan A. Grupp Anne Chew Simon F. Lacey J. Joseph Melenhorst
Journals: Blood (60 papers)Cytotherapy (23 papers)Journal of Clinical Oncology (18 papers)The Journal of Immunology (7 papers)Molecular Therapy (7 papers)
Partner nations: United States Switzerland United Kingdom

In The Last Decade

Bruce L. Levine

250 papers receiving 32.0k citations

Hit Papers

15 papers align trajectories log scale

Unanswered questions following reports of secondary malignancies after CAR-T cell therapy 2024 · 132 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Nature Medicine
2018 Gastroenterology
2017 Molecular Therapy — Methods & Clinical Development
2017 New England Journal of Medicine
2016 Nature reviews. Cancer
2015 Science Translational Medicine
2015 New England Journal of Medicine
2014 New England Journal of Medicine
2014 New England Journal of Medicine
2013 Cancer Immunology Research
2013 New England Journal of Medicine
2013 Cancer Immunology Research
2012 Science Translational Medicine
2011 Science Translational Medicine
2011 New England Journal of Medicine
2010 Blood

Peers

Countries citing papers authored by Bruce L. Levine

Since Specialization

Citations

This map shows the geographic impact of Bruce L. Levine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce L. Levine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce L. Levine more than expected).

Fields of papers citing papers by Bruce L. Levine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce L. Levine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce L. Levine. The network helps show where Bruce L. Levine may publish in the future.

Co-authors

The 25 scholars most cited alongside Bruce L. Levine, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruce L. Levine Line = papers co-authored together Bruce L. Levine links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	International Society for Cell & Gene Therapy Position Paper: Key considerations to support evidence-based cell and gene therapies and oppose marketing of unproven products Cytotherapy ·Laertis Ikonomou, Natividad Cuende, Miguel Forte, Bambi Grilley, Aaron Levine, Megan Munsie, John E.J. Rasko, Leigh Turner, Hamid Reza Bidkhori, Rachele Ciccocioppo, Felix Grignon, Alok Srivastava, Daniel J. Weiss, Patricia J. Zettler, Bruce L. Levine	2023	13
2	A simulation-based comparison of centralized and point-of-care supply chain strategies for autologous cell therapy Cytotherapy ·Kan Wang, Chin-Yuan Tseng, Zhaowei Li, Chip White, Ben Wang, Bruce L. Levine, Andrew D. Fesnak	2023	3
3	The Safety of Bridging Radiation with Anti-BCMA CAR T-Cell Therapy for Multiple Myeloma Clinical Cancer Research ·Shwetha Manjunath, Adam D. Cohen, Simon F. Lacey, Megan M. Davis, Alfred L. Garfall, J. Joseph Melenhorst, Russell Maxwell, W. Tristram Arscott, Amit Maity, Joshua Jones, John P. Plastaras, Edward A. Stadtmauer, Bruce L. Levine, Carl H. June, Michael C. Milone, Ima Paydar	2021	23
4	Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells Cancer Immunology Research ·Saba Ghassemi, Selene Nuñez-Cruz, Roddy S. O’Connor, Joseph A. Fraietta, Prachi Patel, John Scholler, David M. Barrett, Stefan Lundh, Megan M. Davis, Felipe Bedoya, Changfeng Zhang, John Leferovich, Simon F. Lacey, Bruce L. Levine, Stephan A. Grupp, Carl H. June, J. Joseph Melenhorst, Michael C. Milone	2018	212
5	CTL019 Therapy Appears Safe and Effective in Pediatric Patients with Down Syndrome with Relapsed/ Refractory (r/r) Acute Lymphoblastic Leukemia Blood ·Theodore W. Laetsch, Shannon L. Maude, Stephan A. Grupp, Michael W. Boyer, Andrew C. Harris, Muna Qayed, Christine L. Phillips, Michael A. Pulsipher, Henrique Bittencourt, Patricia A. Wood, Karen Thudium Mueller, Yanqui Weng, Carl H. June, Bruce L. Levine, Hidefumi Hiramatsu	2017	14
6	Novel gene and cellular therapy approaches for treating HIV. PubMed ·Vijay Bhoj, Suzanne R. Thibodeaux, Bruce L. Levine	2016	3
7	Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect Blood ·Claudio G. Brunstein, Jeffrey S. Miller, David H. McKenna, Keli L. Hippen, Todd E. DeFor, Darin Sumstad, Julie Curtsinger, Michael R. Verneris, Margaret L. MacMillan, Bruce L. Levine, James L. Riley, Carl H. June, Chap T. Le, Daniel J. Weisdorf, Philip B. McGlave, Bruce R. Blazar, John E. Wagner	2015	303
8	The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28–Costimulated T Cells Prepared for Adoptive Therapy Clinical Cancer Research ·Emese Zsíros, Priyanka Duttagupta, Denarda Dangaj Laniti, Hongzhe Li, Renee Frank, Thomas Garrabrant, Ian S. Hagemann, Bruce L. Levine, Carl H. June, Lin Zhang, Ena Wang, Francesco M. Marincola, Davide Bedognetti, Daniel J. Powell, János L. Tanyi, Michael D. Feldman, Lana E. Kandalaft, George Coukos	2015	48
9	Efficient Trafficking of Chimeric Antigen Receptor (CAR)-Modified T Cells to CSF and Induction of Durable CNS Remissions in Children with CNS/Combined Relapsed/Refractory ALL Blood ·Susan R. Rheingold, Lanyi Nora Chen, Shannon L. Maude, Richard Aplenc, Christine Barker, David M. Barrett, Colleen Callahan, Katherine Cebry, Irina Kulikovskaya, Simon F. Lacey, Bruce L. Levine, Jan J. Melenhorst, Pamela A. Shaw, Anna Sparrow, David T. Teachey, Mark Duckworth, Carl H. June, Stephan A. Grupp	2015	35
10	Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV New England Journal of Medicine ·Pablo Tebas, David Stein, Winson W. Tang, Ian Frank, Shelley Q. Wang, Gary Lee, S. Kaye Spratt, Richard Surosky, Martin Giedlin, Geoff Nichol, Michael C. Holmes, Philip D. Gregory, Dale Ando, Michael Kalos, Ronald G. Collman, Gwendolyn Binder-Scholl, Gabriela Plesa, Wei‐Ting Hwang, Bruce L. Levine, Carl H. June Hit paper breakdown →	2014	973
11	A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside Clinical Cancer Research ·Cheryl Lai-Lai Chiang, Lana E. Kandalaft, János L. Tanyi, Andrea R. Hagemann, Gregory T. Motz, Nikolaos Svoronos, Kathleen T. Montone, Gina Mantia-Smaldone, Lori Smith, Harvey Nisenbaum, Bruce L. Levine, Michael Kalos, Brian J. Czerniecki, Drew A. Torigian, Daniel J. Powell, Rosemarie Mick, George Coukos	2013	181
12	Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies Cancer Immunology Research ·Gregory L. Beatty, Andrew R. Haas, Marcela V. Maus, Drew A. Torigian, Michael C. Soulen, Gabriela Plesa, Anne Chew, Yangbing Zhao, Bruce L. Levine, Steven Μ. Albelda, Michael Kalos, Carl H. June Hit paper breakdown →	2013	693
13	Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma Clinical Cancer Research ·Stephan A. Grupp, Eline T. Luning Prak, Jean Boyer, Kenyetta R. McDonald, Suzanne Shusterman, Edward W. Thompson, Colleen Callahan, Abbas F. Jawad, Bruce L. Levine, Carl H. June, Kathleen E. Sullivan	2012	31
14	HER‐2 pulsed dendritic cell vaccine can eliminate HER‐2 expression and impact ductal carcinoma in situ Cancer ·Anupama Sharma, Ursula Koldovsky, Shuwen Xu, Rosemarie Mick, Robert E. Roses, Elizabeth Fitzpatrick, Susan P. Weinstein, Harvey Nisenbaum, Bruce L. Levine, Kevin R. Fox, Paul Zhang, Gary K. Koski, Brian J. Czerniecki	2012	133
15	Phase I Trial of Adoptive Cell Transfer with Mixed-Profile Type-I/Type-II Allogeneic T Cells for Metastatic Breast Cancer Clinical Cancer Research ·Nancy M. Hardy, Miriam E. Mossoba, Seth M. Steinberg, Vicki Fellowes, Xiaoyi Yan, Frances T. Hakim, Rebecca Babb, Daniele Avila, Juan Gea‐Banacloche, Claude Sportès, Bruce L. Levine, Carl H. June, Hahn Khuu, Ashley Carpenter, Michael Krumlauf, Andrew J. Dwyer, Ronald E. Gress, Daniel H. Fowler, Michael Bishop	2011	12
16	Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics Blood ·Claudio G. Brunstein, Jeffrey S. Miller, Qing Cao, David H. McKenna, Keli L. Hippen, Julie Curtsinger, Todd E. DeFor, Bruce L. Levine, Carl H. June, Pablo Rubinstein, Philip B. McGlave, Bruce R. Blazar, John E. Wagner Hit paper breakdown →	2010	805
17	Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor Cancer Research ·Yangbing Zhao, Edmund K. Moon, Carmine Carpenito, Chrystal M. Paulos, Xiaojun Liu, Andrea Brennan, Anne Chew, Richard G. Carroll, John Scholler, Bruce L. Levine, Steven Μ. Albelda, Carl H. June	2010	366
18	Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia Blood ·Qing Zhou, Meghan E. Munger, Steven L. Highfill, Jakub Tolar, Brenda J. Weigel, Megan Riddle, Arlene H. Sharpe, Daniel A. Vallera, Miyuki Azuma, Bruce L. Levine, Carl H. June, William J. Murphy, David H. Munn, Bruce R. Blazar	2010	230
19	A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients Virology ·Jianqing Yu, Te Lang Wu, Megan K. Liszewski, Jihong Dai, William J. Swiggard, Clifford Baytop, Ian Frank, Bruce L. Levine, Wei Yang, Theodore Theodosopoulos, Una O’Doherty	2008	68
20	Large-Scale Production of CD4+ T Cells from HIV-1-Infected Donors After CD3/CD28 Costimulation* Journal of Hematotherapy ·Bruce L. Levine, Julio Cotte, CAROLYNN C. SMALL, Richard G. Carroll, James L. Riley, Wendy B. Bernstein, Dennis E. Van Epps, R. Alan Hardwick, Carl H. June	1998	98

About Bruce L. Levine

Bruce L. Levine is a scholar working on Oncology, Immunology, Virology, Genetics and Hematology, having authored 255 papers that have together received 32.7k indexed citations. Recurring topics across this work include CAR-T cell therapy research (150 papers), Immune Cell Function and Interaction (65 papers), T-cell and B-cell Immunology (48 papers), Immunotherapy and Immune Responses (47 papers), Virus-based gene therapy research (38 papers), Chronic Lymphocytic Leukemia Research (26 papers), CRISPR and Genetic Engineering (24 papers) and Viral Infectious Diseases and Gene Expression in Insects (23 papers). The work is most often cited by research in Oncology (22.8k citations), Immunology (13.9k citations), Virology (1.3k citations), Genetics (7.8k citations) and Hematology (2.8k citations). Bruce L. Levine has collaborated with scholars based in United States, Switzerland and United Kingdom. Frequent co-authors include Carl H. June, David L. Porter, Michael Kalos, Adam Bagg, Stephan A. Grupp, Anne Chew, Simon F. Lacey, J. Joseph Melenhorst, David T. Teachey and David M. Barrett. Their work appears in journals such as Blood, Cytotherapy, Journal of Clinical Oncology, The Journal of Immunology and Molecular Therapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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