Donald M. O’Rourke

17.9k total citations · 1 hit paper
210 papers, 8.9k citations indexed

About

Donald M. O’Rourke is a scholar working on Genetics, Radiology, Nuclear Medicine and Imaging and Oncology. According to data from OpenAlex, Donald M. O’Rourke has authored 210 papers receiving a total of 8.9k indexed citations (citations by other indexed papers that have themselves been cited), including 105 papers in Genetics, 74 papers in Radiology, Nuclear Medicine and Imaging and 63 papers in Oncology. Recurrent topics in Donald M. O’Rourke's work include Glioma Diagnosis and Treatment (103 papers), Radiomics and Machine Learning in Medical Imaging (34 papers) and CAR-T cell therapy research (34 papers). Donald M. O’Rourke is often cited by papers focused on Glioma Diagnosis and Treatment (103 papers), Radiomics and Machine Learning in Medical Imaging (34 papers) and CAR-T cell therapy research (34 papers). Donald M. O’Rourke collaborates with scholars based in United States, United Kingdom and China. Donald M. O’Rourke's co-authors include Gurpreet S. Kapoor, Ronald L. Wolf, Elias R. Melhem, Stephen Bagley, Kevin Judy, Harish Poptani, Amit Maity, Nabendu Pore, Arati Desai and Ari Melnick and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Donald M. O’Rourke

201 papers receiving 8.8k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IDH mutation impairs histone demethylation and results in a block to cell differentiation

2012 1.5k citations Gurpreet S. Kapoor, Donald M. O’Rourke et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Donald M. O’Rourke United States	53	3.4k	3.4k	2.2k	2.0k	1.8k	210	8.9k
John Laterra United States	60	5.2k 1.5×	2.1k 0.6×	2.5k 1.1×	2.1k 1.1×	1.8k 1.0×	214	11.3k
Joanna J. Phillips United States	50	3.1k 0.9×	3.6k 1.1×	1.1k 0.5×	1.2k 0.6×	1.8k 1.0×	180	7.9k
Steven Brem United States	45	2.9k 0.8×	2.8k 0.8×	1.3k 0.6×	1.5k 0.7×	1.6k 0.9×	193	7.7k
Matija Snuderl United States	40	3.2k 0.9×	2.6k 0.8×	1.7k 0.7×	2.2k 1.1×	2.2k 1.2×	188	9.2k
Daniel P. Cahill United States	44	4.3k 1.2×	4.2k 1.2×	1.3k 0.6×	2.5k 1.2×	2.5k 1.4×	176	9.7k
Kristin Waite United States	38	3.9k 1.1×	4.1k 1.2×	1.1k 0.5×	1.4k 0.7×	1.7k 0.9×	103	10.0k
Gaetano Finocchiaro Italy	51	3.9k 1.1×	3.2k 1.0×	675 0.3×	2.2k 1.1×	1.6k 0.9×	214	8.2k
Ryo Nishikawa Japan	40	3.3k 0.9×	4.3k 1.3×	959 0.4×	2.1k 1.0×	1.9k 1.1×	201	8.4k
Nicholas Butowski United States	41	2.0k 0.6×	3.5k 1.0×	885 0.4×	1.4k 0.7×	1.1k 0.6×	188	6.3k
Ian F. Parney United States	49	2.1k 0.6×	4.3k 1.3×	1.5k 0.7×	2.6k 1.3×	1.2k 0.6×	198	9.3k

Countries citing papers authored by Donald M. O’Rourke

Since Specialization

Citations

This map shows the geographic impact of Donald M. O’Rourke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald M. O’Rourke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald M. O’Rourke more than expected).

Fields of papers citing papers by Donald M. O’Rourke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald M. O’Rourke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald M. O’Rourke. The network helps show where Donald M. O’Rourke may publish in the future.

Co-authorship network of co-authors of Donald M. O’Rourke

This figure shows the co-authorship network connecting the top 25 collaborators of Donald M. O’Rourke. A scholar is included among the top collaborators of Donald M. O’Rourke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Donald M. O’Rourke. Donald M. O’Rourke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Binder, Zev A., Stephen Bagley, Jessica Foster, & Donald M. O’Rourke. (2025). The development of CAR T cells for patients with CNS malignancies. Nature Reviews Clinical Oncology. 23(2). 137–150.

Li, Nannan, Jesse L. Rodriguez, Yibo Yin, et al.. (2024). Armored bicistronic CAR T cells with dominant-negative TGF-β receptor II to overcome resistance in glioblastoma. Molecular Therapy. 32(10). 3522–3538. 22 indexed citations

Abdullaev, Zied, Yuji Matsumoto, Steven Brem, et al.. (2023). EPCO-26. INTRATUMORAL HETEROGENEITY OF GBM IDENTIFIED AND CHARACTERIZED BY A MULTISAMPLING APPROACH AND METHYLATION PROFILING. Neuro-Oncology. 25(Supplement_5). v129–v129.

Hosseini, Seyyed Ali, Ghasem Hajianfar, Isaac Shiri, et al.. (2023). MRI-Based Radiomics Combined with Deep Learning for Distinguishing IDH-Mutant WHO Grade 4 Astrocytomas from IDH-Wild-Type Glioblastomas. Cancers. 15(3). 951–951. 15 indexed citations

Bagley, Stephen, Seyed Ali Nabavizadeh, Jacob E. Till, et al.. (2019). Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study. Clinical Cancer Research. 26(2). 397–407. 81 indexed citations

Sullivan, Patricia Zadnik, Gregory Glauser, Omar Choudhri, et al.. (2019). The LACE+ index fails to predict 30–90 day readmission for supratentorial craniotomy patients: A retrospective series of 238 surgical procedures. Clinical Neurology and Neurosurgery. 182. 79–83. 17 indexed citations

Bagley, Stephen & Donald M. O’Rourke. (2019). Clinical investigation of CAR T cells for solid tumors: Lessons learned and future directions. Pharmacology & Therapeutics. 205. 107419–107419. 100 indexed citations

Mohan, Suyash, et al.. (2019). Detection of occult neoplastic infiltration in the corpus callosum and prediction of overall survival in patients with glioblastoma using diffusion tensor imaging. European Journal of Radiology. 112. 106–111. 18 indexed citations

Singh, Nathan, Elena J. Orlando, Jun Xu, et al.. (2019). Mechanisms of resistance to CAR T cell therapies. Seminars in Cancer Biology. 65. 91–98. 28 indexed citations

10.

Nasrallah, MacLean P., Zev A. Binder, Derek A. Oldridge, et al.. (2019). Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma. Academic Pathology. 6. 1533848481–1533848481. 16 indexed citations

11.

Bakas, Spyridon, Hamed Akbari, Jared Pisapia, et al.. (2017). In Vivo Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The ϕ -Index. Clinical Cancer Research. 23(16). 4724–4734. 63 indexed citations

12.

Bloch, Orin, Michael Lim, Michael E. Sughrue, et al.. (2017). Autologous Heat Shock Protein Peptide Vaccination for Newly Diagnosed Glioblastoma: Impact of Peripheral PD-L1 Expression on Response to Therapy. Clinical Cancer Research. 23(14). 3575–3584. 87 indexed citations

13.

Walsh, Alice M., Gurpreet S. Kapoor, Janine M. Buonato, et al.. (2015). Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma. Molecular Cancer Research. 13(8). 1227–1237. 24 indexed citations

14.

O’Rourke, Donald M., et al.. (2011). Hereditary cerebral haemorrhage with amyloidosis. Lenus, The Irish Health Repository (Dr Steevens Hospital Library). 2 indexed citations

15.

Neznanov, Nickolay, Lubov Neznanova, Roman V. Kondratov, et al.. (2004). The Ability of Protein Tyrosine Phosphatase SHP-1 to Suppress NF κ B Can Be Inhibited by Dominant Negative Mutant of SIRP α. DNA and Cell Biology. 23(3). 175–182. 16 indexed citations

16.

Qian, Xiaolan, et al.. (1999). Domain-specific Interactions between the p185 and Epidermal Growth Factor Receptor Kinases Determine Differential Signaling Outcomes. Journal of Biological Chemistry. 274(2). 574–583. 30 indexed citations

17.

Park, Byeong‐Woo, Donald M. O’Rourke, Qiang Wang, et al.. (1999). Induction of the Tat-binding protein 1 gene accompanies the disabling of oncogenic erbB receptor tyrosine kinases. Proceedings of the National Academy of Sciences. 96(11). 6434–6438. 16 indexed citations

18.

O’Rourke, Donald M., James G. Davis, Chuan-Jin Wu, et al.. (1998). Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: implications for subdomain contributions to receptor assembly. Oncogene. 16(9). 1197–1207. 47 indexed citations

19.

Qian, Xiaolan, Donald M. O’Rourke, Jeffrey A. Drebin, et al.. (1997). Identification of pl85 ^neu Sequences Required for Monoclonal Antibody- or Ligand-Mediated Receptor Signal Attenuation. DNA and Cell Biology. 16(12). 1395–1405. 7 indexed citations

20.

Qian, Xiaolan, Donald M. O’Rourke, Hongbo Zhao, & M I Greene. (1996). Inhibition of p185neu kinase activity and cellular transformation by co-expression of a truncated neu protein.. PubMed. 13(10). 2149–57. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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