Donald M. O’Rourke

17.9k citations

210 papers · 8.9k indexed · 1 hit paper · h-index 53

Molecular Biology top 2%
Genetics top 0.1%
Radiology, Nuclear Medicine and Imaging top 0.5%
Oncology top 1%
Cancer Research top 0.5%

Co-authors: Gurpreet S. Kapoor Ronald L. Wolf Elias R. Melhem Stephen Bagley Harish Poptani Kevin Judy Nabendu Pore Amit Maity
Topics: Glioma Diagnosis and Treatment (103 papers)Radiomics and Machine Learning in Medical Imaging (34 papers)CAR-T cell therapy research (34 papers)
Cited by: Genetics Cancer Research Radiology, Nuclear Medicine and Imaging
Journals: Nature Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United States United Kingdom China

In The Last Decade

Donald M. O’Rourke

201 papers receiving 8.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IDH mutation impairs histone demethylation and results in a block to cell differentiation

2012 1.5k citations Gurpreet S. Kapoor, Donald M. O’Rourke et al. profile →

Peers

Countries citing papers authored by Donald M. O’Rourke

Since Specialization

Citations

This map shows the geographic impact of Donald M. O’Rourke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald M. O’Rourke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald M. O’Rourke more than expected).

Fields of papers citing papers by Donald M. O’Rourke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald M. O’Rourke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald M. O’Rourke. The network helps show where Donald M. O’Rourke may publish in the future.

Co-authorship network of co-authors of Donald M. O’Rourke

This figure shows the co-authorship network connecting the top 25 collaborators of Donald M. O’Rourke. A scholar is included among the top collaborators of Donald M. O’Rourke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Donald M. O’Rourke. Donald M. O’Rourke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model 2025 ·Stem Cell Reports ·Yusha Sun,(unknown),Zhijian Zhang,(unknown),Yicheng Wu,Weifan Dong,Daniel Y. Zhang,Yao Fu,Feng Zhang,Zev A. Binder,Emily Ling-Lin Pai,MacLean P. Nasrallah,Kimberly M. Christian,Donald M. O’Rourke,Nicolas Toni,Guo‐li Ming,Hongjun Song	2
2	The development of CAR T cells for patients with CNS malignancies 2025 ·Nature Reviews Clinical Oncology ·Zev A. Binder,Stephen Bagley,Jessica Foster,Donald M. O’Rourke	0
3	Novel tri-specific T-cell engager targeting IL-13Rα2 and EGFRvIII provides long-term survival in heterogeneous GBM challenge and promotes antitumor cytotoxicity with patient immune cells 2024 ·Journal for ImmunoTherapy of Cancer ·Daniel H. Park,Pratik Bhojnagarwala,Kevin Liaw,Devivasha Bordoloi,Nicholas J. Tursi,(unknown),Zev A. Binder,Donald M. O’Rourke,David B. Weiner	4
4	CTIM-40. EARLY RADIOGRAPHIC RESPONSE AND ENGRAFTMENT OF PHASE I FIRST-IN-HUMAN BICISTRONIC CAR T CELLS CORRELATE WITH REAL-TIME AUTOLOGOUS GBM ORGANOID CYTOLYSIS 2023 ·Neuro-Oncology ·Meghan Logun,Stephen Bagley,(unknown),Daniel Zhang,Yusha Sun,Guo‐li Ming,Ali Nabavizadeh,Amy Marshall,Eileen Maloney,Wei‐Ting Hwang,Joseph A. Fraietta,Vanessa Gonzalez,Arati Desai,Linda J. Bagley,Elizabeth O. Hexner,MacLean P. Nasrallah,Hongjun Song,Zev A. Binder,Donald M. O’Rourke	1
5	Non-Invasive Assessment of Isocitrate Dehydrogenase-Mutant Gliomas Using Optimized Proton Magnetic Resonance Spectroscopy on a Routine Clinical 3-Tesla MRI 2023 ·Cancers ·(unknown),(unknown),(unknown),Gaurav Verma,(unknown),Donald M. O’Rourke,John Y. K. Lee,Arati Desai,Sanjeev Chawla,Suyash Mohan	6
6	MRI-Based Radiomics Combined with Deep Learning for Distinguishing IDH-Mutant WHO Grade 4 Astrocytomas from IDH-Wild-Type Glioblastomas 2023 ·Cancers ·Seyyed Ali Hosseini,(unknown),Ghasem Hajianfar,Isaac Shiri,Stijn Servaes,Pedro Rosa‐Neto,(unknown),MacLean P. Nasrallah,Donald M. O’Rourke,Suyash Mohan,Sanjeev Chawla	15
7	EPCO-26. INTRATUMORAL HETEROGENEITY OF GBM IDENTIFIED AND CHARACTERIZED BY A MULTISAMPLING APPROACH AND METHYLATION PROFILING 2023 ·Neuro-Oncology ·(unknown),Zied Abdullaev,Yuji Matsumoto,Steven Brem,Donald M. O’Rourke,Christos Davatzikos,Kenneth Aldape,MacLean P. Nasrallah	0
8	Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase 2021 ·Molecular Therapy ·Joseph S. Durgin,Radhika Thokala,Lexus R. Johnson,(unknown),John Leferovich,Vijay Bhoj,Saba Ghassemi,Michael C. Milone,Zev A. Binder,Donald M. O’Rourke,Roddy S. O’Connor	21
9	Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma 2020 ·Science Translational Medicine ·Menggui Huang,Duo Zhang,(unknown),(unknown),(unknown),Chunsheng Li,Lin Zhang,Eric C. Holland,Lutian Yao,Ling Qin,Zev A. Binder,Donald M. O’Rourke,Steven Brem,Constantinos Koumenis,Yanqing Gong,Yi Fan	106
10	Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study 2019 ·Clinical Cancer Research ·Stephen Bagley,Seyed Ali Nabavizadeh,(unknown),Jacob E. Till,Jeffrey B. Ware,(unknown),(unknown),(unknown),(unknown),(unknown),Theresa Christensen,Stephanie S. Yee,MacLean P. Nasrallah,Jennifer J.D. Morrissette,Zev A. Binder,Donald M. O’Rourke,Andrew J. Cucchiara,Steven Brem,Arati Desai,Erica L. Carpenter	81
11	Detection of occult neoplastic infiltration in the corpus callosum and prediction of overall survival in patients with glioblastoma using diffusion tensor imaging 2019 ·European Journal of Radiology ·Suyash Mohan,Sumei Wang,(unknown),(unknown),Sanjeev Chawla,Donald M. O’Rourke,Harish Poptani	18
12	Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma 2019 ·Academic Pathology ·MacLean P. Nasrallah,Zev A. Binder,Derek A. Oldridge,Jianhua Zhao,David Lieberman,Jacquelyn J. Roth,Christopher D. Watt,(unknown),Eva Klinman,Robert Daber,Arati Desai,Steven Brem,Donald M. O’Rourke,Jennifer J.D. Morrissette	16
13	Mechanisms of resistance to CAR T cell therapies 2019 ·Seminars in Cancer Biology ·Nathan Singh,Elena J. Orlando,Jun Xu,Jie Xu,Zev A. Binder,McKensie Collins,Donald M. O’Rourke,J. Joseph Melenhorst	28
14	In Vivo Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The ϕ -Index 2017 ·Clinical Cancer Research ·Spyridon Bakas,Hamed Akbari,Jared Pisapia,María Martínez-Lage,Martin Rozycki,Saima Rathore,Nadia Dahmane,Donald M. O’Rourke,Christos Davatzikos	63
15	Autologous Heat Shock Protein Peptide Vaccination for Newly Diagnosed Glioblastoma: Impact of Peripheral PD-L1 Expression on Response to Therapy 2017 ·Clinical Cancer Research ·Orin Bloch,Michael Lim,Michael E. Sughrue,Ricardo J. Komotar,John M. Abrahams,Donald M. O’Rourke,Anthony D’Ambrosio,Jeffrey N. Bruce,Andrew T. Parsa	87
16	Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma 2015 ·Molecular Cancer Research ·Alice M. Walsh,Gurpreet S. Kapoor,Janine M. Buonato,Lijoy K. Mathew,Yingtao Bi,Ramana V. Davuluri,María Martínez-Lage,M. Celeste Simon,Donald M. O’Rourke,Matthew J. Lazzara	24
17	Hereditary cerebral haemorrhage with amyloidosis 2011 ·Lenus, The Irish Health Repository (Dr Steevens Hospital Library) ·(unknown),Donald M. O’Rourke,Jane Cryan,(unknown),Francesca Brett,Michael Farrell,Joan T. Moroney	2
18	Sustained Mitogen-Activated Protein Kinase Activation Is Induced by Transforming erbB Receptor Complexes 1999 ·DNA and Cell Biology ·Chuan-Jin Wu,Xiaolan Qian,Donald M. O’Rourke	30
19	Induction of the Tat-binding protein 1 gene accompanies the disabling of oncogenic erbB receptor tyrosine kinases 1999 ·Proceedings of the National Academy of Sciences ·Byeong‐Woo Park,Donald M. O’Rourke,Qiang Wang,James G. Davis,Andrew Post,Xiaolan Qian,Mark I. Greene	16
20	Inhibition of p185neu kinase activity and cellular transformation by co-expression of a truncated neu protein. 1996 ·PubMed ·Xiaolan Qian,Donald M. O’Rourke,Hongbo Zhao,M I Greene	18

About Donald M. O’Rourke

Donald M. O’Rourke is a scholar working on Genetics, Radiology, Nuclear Medicine and Imaging and Oncology, having authored 210 papers that have together received 8.9k indexed citations. Recurring topics across this work include Glioma Diagnosis and Treatment (103 papers), Radiomics and Machine Learning in Medical Imaging (34 papers) and CAR-T cell therapy research (34 papers). The work is most often cited by research in Genetics (3.4k citations), Cancer Research (1.8k citations) and Radiology, Nuclear Medicine and Imaging (2.2k citations). Donald M. O’Rourke has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Gurpreet S. Kapoor, Ronald L. Wolf, Elias R. Melhem, Stephen Bagley, Harish Poptani, Kevin Judy, Nabendu Pore, Amit Maity, Arati Desai and María E. Figueroa. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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