Stephan A. Grupp

62.3k citations

326 papers · 29.3k indexed · 16 hit papers · h-index 74

Impact in

Oncology top 0.01%
- CAR-T cell therapy research
Immunology top 0.1%
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses

Papers in

Hematology 89
- Hematopoietic Stem Cell Transplantation 64
- Acute Myeloid Leukemia Research 26
Oncology 196
- CAR-T cell therapy research 172

Co-authors: Carl H. June David T. Teachey David L. Porter David M. Barrett Bruce L. Levine Shannon L. Maude Michael Kalos Anne Chew
Journals: Blood (104 papers)Journal of Clinical Oncology (30 papers)Biology of Blood and Marrow Transplantation (23 papers)Transplantation and Cellular Therapy (12 papers)Bone Marrow Transplantation (12 papers)
Partner nations: United States Canada Germany

In The Last Decade

Stephan A. Grupp

311 papers receiving 28.8k citations

Hit Papers

15 papers align trajectories log scale

Unanswered questions following reports of secondary malignancies after CAR-T cell therapy 2024 · 132 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Nature Medicine
2023 Science
2020 Nature Reviews Drug Discovery
2019 JAMA
2016 Critical Care Medicine
2015 Science Translational Medicine
2015 Blood
2014 Blood
2014 New England Journal of Medicine
2014 Blood
2014 The Cancer Journal
2013 New England Journal of Medicine
2013 Blood
2011 Science Translational Medicine
2010 New England Journal of Medicine
2009 Molecular Therapy

Peers

Countries citing papers authored by Stephan A. Grupp

Since Specialization

Citations

This map shows the geographic impact of Stephan A. Grupp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephan A. Grupp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephan A. Grupp more than expected).

Fields of papers citing papers by Stephan A. Grupp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephan A. Grupp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephan A. Grupp. The network helps show where Stephan A. Grupp may publish in the future.

Co-authors

The 25 scholars most cited alongside Stephan A. Grupp, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Stephan A. Grupp Line = papers co-authored together Stephan A. Grupp links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Quadriparesis and paraparesis following chimeric antigen receptor T-cell therapy in children and adolescents Blood ·Caroline Diorio, Софья Борисовна Владимирова, Diego A. Espinoza, Brenda Banwell, Amit Bar‐Or, Amanda M. DiNofia, Allison Barz Leahy, Zachary Martinez, Regina M. Myers, Sarah Hopkins, Susan R. Rheingold, David T. Teachey, Angela N. Viaene, Lisa Wray, Shannon L. Maude, Stephan A. Grupp, Jennifer L. McGuire	2024	10
2	Therapies and outcomes following extramedullary relapse of pediatric and young adult ALL after CD19 CAR T-cell therapy Blood Advances ·A.G. Fountain, Amanda M. DiNofia, 宏宮崎, Yimei Li, Susan R. Rheingold, Allison Barz Leahy, Lisa Wray, Colleen Callahan, Diane Baniewicz, Brayan R. Ruiz Lopez, Kelly Getz, Richard Aplenc, Shannon L. Maude, Stephan A. Grupp, Regina M. Myers	2024	1
3	Cost-Effective Manufacture and Promising Initial Efficacy of huCART19 Cells Manufactured Using the Clinimacs Prodigy Platform Blood ·Allison Barz Leahy, Jennifer L. Brogdon, Qixi Zhong, Amanda M. DiNofia, Joseph A. Fraietta, 閣郎青柳, Stephan Kadauke, H. Özkaya, Yimei Li, Shannon L. Maude, Regina M. Myers, A. Marzari-Chiesa, Donna Washburn, Sjostedt SMS, Lei Wang, Yongping Wang, Stephan A. Grupp	2024	1
4	CD4 ⁺ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response Cancer Medicine ·Luis Gil‐de‐Gómez, 正彦新宮, Jessica H. Lee, Stephan A. Grupp, Gregor S. D. Reid, Alix E. Seif	2024	1
5	The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia Leukemia ·Ali Farrokhi, Narjiss Bakhtyari, 晋偉朱, Nedim Sakçı, Salam Oukal, Katherine Martínez Rodríguez, Juan Carlos Parodi Mintegui, Nenad Radosevic, Sumin Jo, Deng Xi-Qing Zhang Pei-Fang, Jeannine B. Songer, S.A.Asthaputre, Franziska Auer, Julia Hauer, Stephan A. Grupp, Patrice Eydoux, Philipp F. Lange, Alix E. Seif, Christopher A. Maxwell, Gregor S. D. Reid	2024	2
6	Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies Clinical Cancer Research ·Yimei Li, Wei‐Ting Hwang, Shannon L. Maude, David T. Teachey, Noelle V. Frey, Regina M. Myers, Allison Barz Leahy, Putu Agus Grantika, David L. Porter, Stephan A. Grupp, Pamela A. Shaw	2022	8
7	Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing Cancer Immunology Research ·Gregory M. Chen, Qianqian Suna, Jessica Perazzelli, Stephan A. Grupp, David M. Barrett, Kai Tan	2022	2
8	Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy Cancer Discovery ·Gregory M. Chen, Changya Chen, Rajat K. Das, Peng Gao, Chia‐Hui Chen, Shovik Bandyopadhyay, Yangyang Ding, Yasin Uzun, Wenbao Yu, Qin Zhu, Regina M. Myers, Stephan A. Grupp, David M. Barrett, Kai Tan	2021	124
9	Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers Cancer Discovery ·Rajat K. Das, Brayan R. Ruiz Lopez, Stephan A. Grupp, David M. Barrett	2019	174
10	Subcutaneous immunoglobulin replacement following CD19‐specific chimeric antigen receptor T‐cell therapy for B‐cell acute lymphoblastic leukemia in pediatric patients Pediatric Blood & Cancer ·Danielle E. Arnold, Shannon L. Maude, Colleen Callahan, Amanda M. DiNofia, Stephan A. Grupp, Jennifer Heimall	2019	35
11	High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model Cancer Immunology Research ·Sarah A. Richman, Selene Nuñez-Cruz, Babak Moghimi, Lucy Z. Li, Zachary T. Gershenson, Zissimos P. Mourelatos, David M. Barrett, Stephan A. Grupp, Michael C. Milone	2017	202
12	Efficacy and Safety of CTL019 in the First US Phase II Multicenter Trial in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of an Interim Analysis Blood ·Shannon L. Maude, Michael A. Pulsipher, Michael W. Boyer, Stephan A. Grupp, Stella M. Davies, Christine L. Phillips, Michael R. Verneris, Keith J. August, Krysta Schlis, Timothy A. Driscoll, Rajen Mody, Christian M. Capitini, Carl H. June, Bruce L. Levine, Patricia A. Wood, Lan Yi, John E. Levine	2016	59
13	Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy Journal of Immunological Methods ·Fangfang Chen, David T. Teachey, Edward Pequignot, Noelle V. Frey, David Porter, Shannon L. Maude, Stephan A. Grupp, Carl H. June, J. Joseph Melenhorst, Simon F. Lacey	2016	141
14	Efficient Trafficking of Chimeric Antigen Receptor (CAR)-Modified T Cells to CSF and Induction of Durable CNS Remissions in Children with CNS/Combined Relapsed/Refractory ALL Blood ·Susan R. Rheingold, Batbayar Tsedendamba, Shannon L. Maude, Richard Aplenc, Angel S. W. Pang, David M. Barrett, Colleen Callahan, A.E. Souvorov, Irina Kulikovskaya, Simon F. Lacey, Bruce L. Levine, Jan J. Melenhorst, Pamela A. Shaw, Donna Washburn, David T. Teachey, 胡志立, Carl H. June, Stephan A. Grupp	2015	35
15	Nature of Tumor Control by Permanently and Transiently Modified GD2 Chimeric Antigen Receptor T Cells in Xenograft Models of Neuroblastoma Cancer Immunology Research ·Nathan Singh, Xiaojun Liu, Jessica Hulitt, Shuguang Jiang, Carl H. June, Stephan A. Grupp, David M. Barrett, Yangbing Zhao	2014	65
16	Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells Blood ·Saar Gill, Sarah K. Tasian, Marco Ruella, Olga Shestova, Yong Li, David L. Porter, Martin Carroll, Gwenn Danet-Desnoyers, John Scholler, Stephan A. Grupp, Carl H. June, Michael Kalos	2014	363
17	iNKT Cell Cytotoxic Responses Control T-Lymphoma Growth In Vitro and In Vivo Cancer Immunology Research ·Hamid Bassiri, Rupali Das, Peng Guan, David M. Barrett, Patrick J. Brennan, Pinaki P. Banerjee, Susan J. Wiener, Jordan S. Orange, Michael B. Brenner, Stephan A. Grupp, Kim E. Nichols	2013	47
18	Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy Blood ·David T. Teachey, Susan R. Rheingold, Shannon L. Maude, Gerhard Zugmaier, David M. Barrett, Alix E. Seif, Kim E. Nichols, Arina Santos Ribeiro, Michael Kalos, Robert A. Berg, Julie C. Fitzgerald, Richard Aplenc, Lia Gore, Stephan A. Grupp Hit paper breakdown →	2013	459
19	Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma Clinical Cancer Research ·Stephan A. Grupp, Eline T. Luning Prak, Jean Boyer, Kenyetta R. McDonald, Suzanne Shusterman, Awadhesh Kumar, Colleen Callahan, Abbas F. Jawad, Bruce L. Levine, Carl H. June, Kathleen E. Sullivan	2012	31
20	Immunosurveillance and Survivin-Specific T-Cell Immunity in Children With High-Risk Neuroblastoma Journal of Clinical Oncology ·Christina Coughlin, Mark D. Fleming, Richard G. Carroll, Bruce Pawel, Michael D. Hogarty, Xiaochuan Shan, Barbara A. Vance, Jarish N. Cohen, Jun Zhao, Andrea del Pilar Correa, Walter L. Corwin, Y L O, Jack L. Pinkus, Geraldine S. Pinkus, John M. Maris, Stephan A. Grupp, Robert H. Vonderheide	2006	73

About Stephan A. Grupp

Stephan A. Grupp is a scholar working on Hematology, Oncology, Genetics, Immunology and Neurology, having authored 326 papers that have together received 29.3k indexed citations. Recurring topics across this work include CAR-T cell therapy research (172 papers), Acute Lymphoblastic Leukemia research (83 papers), Hematopoietic Stem Cell Transplantation (64 papers), Virus-based gene therapy research (51 papers), Immune Cell Function and Interaction (48 papers), Neuroblastoma Research and Treatments (46 papers), Chronic Lymphocytic Leukemia Research (26 papers) and Acute Myeloid Leukemia Research (26 papers). The work is most often cited by research in Oncology (21.4k citations), Immunology (9.0k citations), Hematology (3.8k citations), Genetics (6.5k citations) and Neurology (3.2k citations). Stephan A. Grupp has collaborated with scholars based in United States, Canada and Germany. Frequent co-authors include Carl H. June, David T. Teachey, David L. Porter, David M. Barrett, Bruce L. Levine, Shannon L. Maude, Michael Kalos, Anne Chew, Susan R. Rheingold and David Porter. Their work appears in journals such as Blood, Journal of Clinical Oncology, Biology of Blood and Marrow Transplantation, Transplantation and Cellular Therapy and Bone Marrow Transplantation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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