Christine E. Brown

15.7k total citations · 2 hit papers
176 papers, 9.5k citations indexed

About

Christine E. Brown is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Christine E. Brown has authored 176 papers receiving a total of 9.5k indexed citations (citations by other indexed papers that have themselves been cited), including 119 papers in Oncology, 50 papers in Immunology and 48 papers in Molecular Biology. Recurrent topics in Christine E. Brown's work include CAR-T cell therapy research (107 papers), Immunotherapy and Immune Responses (29 papers) and Immune Cell Function and Interaction (25 papers). Christine E. Brown is often cited by papers focused on CAR-T cell therapy research (107 papers), Immunotherapy and Immune Responses (29 papers) and Immune Cell Function and Interaction (25 papers). Christine E. Brown collaborates with scholars based in United States, Canada and China. Christine E. Brown's co-authors include Stephen J. Forman, Michael C. Jensen, Renate Starr, Behnam Badie, Brenda Aguilar, Jerry L. Workman, Alan B. Sachs, Julie R. Ostberg, Michael E. Barish and Dongrui Wang and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nature Communications.

In The Last Decade

Christine E. Brown

172 papers receiving 9.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma

2015 592 citations Christine E. Brown, Behnam Badie et al. Clinical Cancer Research profile →
IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype

2019 324 citations Darya Alizadeh, Robyn A. Wong et al. Cancer Immunology Research profile →

Peers

Countries citing papers authored by Christine E. Brown

Since Specialization

Citations

This map shows the geographic impact of Christine E. Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christine E. Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christine E. Brown more than expected).

Fields of papers citing papers by Christine E. Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christine E. Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christine E. Brown. The network helps show where Christine E. Brown may publish in the future.

Co-authorship network of co-authors of Christine E. Brown

This figure shows the co-authorship network connecting the top 25 collaborators of Christine E. Brown. A scholar is included among the top collaborators of Christine E. Brown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christine E. Brown. Christine E. Brown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Label-free in-line characterization of immune cell culture using quantitative phase imaging 2025 ·npj Regenerative Medicine ·(unknown), (unknown), (unknown), (unknown), (unknown), Bryan Wang, (unknown), (unknown), (unknown), (unknown), (unknown), Ye Li, (unknown), Jing Li, Christine E. Brown, Gabriel A. Kwong, Stephen Balakirsky, Krishnendu Roy, Francisco E. Robles	0
2	Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme 2024 ·Cells ·David Akhavan, (unknown), John D. Jeppson, Brenda Aguilar, Robyn A. Wong, (unknown), Susanta Hui, Jeffrey Y.C. Wong, Stephen J. Forman, Darya Alizadeh, Christine E. Brown	3
3	IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma 2024 ·Neuro-Oncology ·Andrew J. Hou, (unknown), Benjamin R. Uy, (unknown), (unknown), Begonya Comin-Anduix, (unknown), Zoran Galić, Su Phyu, Hideho Okada, (unknown), Joshua J. Breunig, Christine E. Brown, David A. Nathanson, Robert M. Prins, Yvonne Y. Chen	32
4	Favorable Activity of CD19-Targeted Chimeric Antigen Receptor (CD19CAR) T Cell Therapy in Adults with Relapsed/ Refractory (R/R) ALL Including Extramedullary Disease (EMD) and Ph-like Genotype, Using Naive/Memory (Tn/ Mem) Derived T Cells 2022 ·Transplantation and Cellular Therapy ·Ibrahim Aldoss, Samer K. Khaled, M. Suzette Blanchard, Xiuli Wang, Jamie R. Wagner, Mary Ann Clark, Jennifer Simpson, Jinny Paul, Anthony S. Stein, Vinod Pullarkat, Amandeep Salhotra, Monzr M. Al Malki, Sandra P. Thomas, Lihua E. Budde, Guido Marcucci, Christine E. Brown, Stephen J. Forman	1
5	Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy 2022 ·PLoS Computational Biology ·(unknown), Xin Yang, (unknown), Margarita Gutova, Christine E. Brown, Russell C. Rockne	14
6	Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma 2022 ·Neoplasia ·Michael E. Barish, Lihong Weng, (unknown), Yubo Zhai, Renate Starr, Massimo D’Apuzzo, Russell C. Rockne, Haiqing Li, Behnam Badie, Stephen J. Forman, Christine E. Brown	11
7	IFNγ Is Critical for CAR T Cell–Mediated Myeloid Activation and Induction of Endogenous Immunity 2021 ·Cancer Discovery ·Darya Alizadeh, Robyn A. Wong, Sharareh Gholamin, (unknown), Maryam Aftabizadeh, Xin Yang, Joseph R. Pecoraro, John D. Jeppson, Dongrui Wang, Brenda Aguilar, Renate Starr, Claire B. Larmonier, Nicolas Larmonier, (unknown), Xiwei Wu, Antoni Ribas, Behnam Badie, Stephen J. Forman, Christine E. Brown	103
8	A phase 1 study to evaluate chimeric antigen receptor (CAR) T cells incorporating a chlorotoxin tumor-targeting domain for patients with MMP2+ Recurrent or progressive glioblastoma (NCT04214392). 2021 ·Journal of Clinical Oncology ·Behnam Badie, Michael E. Barish, Ammar Chaudhry, Massimo D’Apuzzo, Stephen J. Forman, Jana Portnow, Shirong Wang, Julie A. Ressler, Jennifer Simpson, Julie Kilpatrick, (unknown), Jamie R. Wagner, Suzette Blanchard, Dongrui Wang, Christine E. Brown	9
9	CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies 2020 ·Cancer Discovery ·Dongrui Wang, Briana C. Prager, Ryan C. Gimple, Brenda Aguilar, Darya Alizadeh, Hongzhen Tang, Deguan Lv, Renate Starr, Alfonso Brito, Qiulian Wu, Leo J.Y. Kim, Zhixin Qiu, Lin Peng, Michael H. Lorenzini, Behnam Badie, Stephen J. Forman, Qi Xie, Christine E. Brown, Jeremy N. Rich	121
10	Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma 2020 ·Nature Communications ·Eugenia Zah, (unknown), (unknown), Uyen Tran, (unknown), (unknown), Xiuli Wang, Christine E. Brown, Yvonne Y. Chen	148
11	Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data 2020 ·Journal of The Royal Society Interface ·Prativa Sahoo, Xin Yang, Daniel Abler, (unknown), Vikram Adhikarla, David Frankhouser, Heyrim Cho, (unknown), Dongrui Wang, Michael E. Barish, Margarita Gutova, Sergio Branciamore, Christine E. Brown, Russell C. Rockne	68
12	IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype breakdown → 2019 ·Cancer Immunology Research ·Darya Alizadeh, Robyn A. Wong, Xin Yang, Dongrui Wang, Joseph R. Pecoraro, Cheng-Fu Kuo, Brenda Aguilar, Yue Qi, David K. Ann, Renate Starr, Ryan Urak, Xiuli Wang, Stephen J. Forman, Christine E. Brown	324
13	Lenalidomide Enhances the Function of CS1 Chimeric Antigen Receptor–Redirected T Cells Against Multiple Myeloma 2017 ·Clinical Cancer Research ·Xiuli Wang, Miriam Walter, Ryan Urak, Lihong Weng, Christian Huynh, Laura Lim, ChingLam W. Wong, Wen-Chung Chang, Sandra H. Thomas, James F. Sanchez, Lu Yang, Christine E. Brown, Flavia Pichiorri, Myo Htut, Amrita Krishnan, Stephen J. Forman	149
14	Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer 2017 ·OncoImmunology ·Saul J. Priceman, Ethan Gerdts, Dileshni Tilakawardane, (unknown), John P. Murad, Anthony K. Park, Brook Jeang, Yukiko Yamaguchi, Xin Yang, Ryan Urak, Lihong Weng, Wen-Chung Chang, Sarah Wright, Sumanta K. Pal, Robert E. Reiter, Anna M. Wu, Christine E. Brown, Stephen J. Forman	120
15	CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells 2015 ·Clinical Cancer Research ·Xiuli Wang, ChingLam W. Wong, Ryan Urak, Armen Mardiros, Lihua E. Budde, Wen-Chung Chang, Sandra H. Thomas, Christine E. Brown, Corinna La Rosa, Don J. Diamond, Michael C. Jensen, Ryotaro Nakamura, John A. Zaia, Stephen J. Forman	52
16	Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma breakdown → 2015 ·Clinical Cancer Research ·Christine E. Brown, Behnam Badie, Michael E. Barish, Lihong Weng, Julie R. Ostberg, Wen-Chung Chang, Araceli Naranjo, Renate Starr, Jamie R. Wagner, Christine L. Wright, Yubo Zhai, James R. Bading, Julie A. Ressler, Jana Portnow, Massimo D’Apuzzo, Stephen J. Forman, Michael C. Jensen	592
17	TLR9 Is Critical for Glioma Stem Cell Maintenance and Targeting 2014 ·Cancer Research ·Andreas Herrmann, Gregory Cherryholmes, Anne Schroeder, Jillian Phallen, Darya Alizadeh, Xin Hong, Tianyi Wang, Heehyoung Lee, Christoph Lahtz, Piotr Swiderski, Brian Armstrong, Claudia Kowolik, Gary L. Gallia, Michael Lim, Christine E. Brown, Behnam Badie, Stephen J. Forman, Marcin Kortylewski, Richard Jove, Hua Yu	60
18	Stem-like Tumor-Initiating Cells Isolated from IL13Rα2 Expressing Gliomas Are Targeted and Killed by IL13-Zetakine–Redirected T Cells 2012 ·Clinical Cancer Research ·Christine E. Brown, Renate Starr, Brenda Aguilar, (unknown), Catalina Martínez, Massimo D’Apuzzo, Michael E. Barish, Stephen J. Forman, Michael C. Jensen	185
19	Induction of Anti-Glioma Natural Killer Cell Response following Multiple Low-Dose Intracerebral CpG Therapy 2010 ·Clinical Cancer Research ·Darya Alizadeh, Leying Zhang, Christine E. Brown, (unknown), Michael C. Jensen, Behnam Badie	64
20	Recognition and Killing of Brain Tumor Stem-Like Initiating Cells by CD8+ Cytolytic T Cells 2009 ·Cancer Research ·Christine E. Brown, Renate Starr, Catalina Martínez, Brenda Aguilar, Massimo D’Apuzzo, Иван Тодоров, (unknown), Behnam Badie, Michael Hudecek, Stanley R. Riddell, Michael C. Jensen	113

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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