Richard C. Boucher

66.4k total citations · 21 hit papers
482 papers, 46.2k citations indexed

About

Richard C. Boucher is a scholar working on Pulmonary and Respiratory Medicine, Molecular Biology and Physiology. According to data from OpenAlex, Richard C. Boucher has authored 482 papers receiving a total of 46.2k indexed citations (citations by other indexed papers that have themselves been cited), including 345 papers in Pulmonary and Respiratory Medicine, 128 papers in Molecular Biology and 71 papers in Physiology. Recurrent topics in Richard C. Boucher's work include Cystic Fibrosis Research Advances (252 papers), Neonatal Respiratory Health Research (210 papers) and Tracheal and airway disorders (67 papers). Richard C. Boucher is often cited by papers focused on Cystic Fibrosis Research Advances (252 papers), Neonatal Respiratory Health Research (210 papers) and Tracheal and airway disorders (67 papers). Richard C. Boucher collaborates with scholars based in United States, Germany and United Kingdom. Richard C. Boucher's co-authors include Michael R. Knowles, M. Jackson Stutts, Eduardo R. Lazarowski, Barbara R. Grubb, James R. Yankaskas, Scott H. Randell, Robert Tarran, Anthony M. Paradiso, J. T. Gatzy and Brian Button and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Richard C. Boucher

468 papers receiving 45.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

2002 919 citations Dieter Worlitzsch, Robert Tarran et al. Journal of Clinical Investigation profile →
CFTR as a cAMP-Dependent Regulator of Sodium Channels

1995 895 citations Richard C. Boucher et al. Science profile →
Mucus clearance as a primary innate defense mechanism for mammalian airways

2002 863 citations Michael R. Knowles, Richard C. Boucher Journal of Clinical Investigation profile →
Mucus clearance as a primary innate defense mechanism for mammalian airways

2002 800 citations Michael R. Knowles, Richard C. Boucher Journal of Clinical Investigation profile →
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

2002 778 citations Dieter Worlitzsch, Robert Tarran et al. Journal of Clinical Investigation profile →
An Animal Model for Cystic Fibrosis Made by Gene Targeting

1992 744 citations Richard C. Boucher et al. Science profile →
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

2004 700 citations Richard C. Boucher et al. profile →
Correction: Corrigendum: Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo

2014 675 citations Richard C. Boucher et al. profile →
A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

2012 615 citations Brian Button, Camille Ehré et al. Science profile →
Submucosal glands are the predominant site of CFTR expression in the human bronchus

1992 514 citations James R. Yankaskas, Richard C. Boucher et al. profile →
Mucus Clearance and Lung Function in Cystic Fibrosis with Hypertonic Saline

2006 511 citations William D. Bennett, Kirby L. Zeman et al. profile →
New concepts of the pathogenesis of cystic fibrosis lung disease

2003 485 citations Richard C. Boucher profile →
Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

1986 465 citations Richard C. Boucher, Michael R. Knowles et al. Journal of Clinical Investigation profile →
Increased Bioelectric Potential Difference across Respiratory Epithelia in Cystic Fibrosis

1981 449 citations Michael R. Knowles, John T. Gatzy et al. profile →
Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis

1991 402 citations Michael R. Knowles, Richard C. Boucher et al. profile →
Abnormal Ion Permeation Through Cystic Fibrosis Respiratory Epithelium

1983 374 citations Michael R. Knowles, J. T. Gatzy et al. Science profile →
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

2020 248 citations Caitlin E. Edwards, Takanori Asakura et al. profile →
Defective Epithelial Chloride Transport in a Gene-Targeted Mouse Model of Cystic Fibrosis

1992 244 citations Richard C. Boucher et al. Science profile →
Muco-Obstructive Lung Diseases

2019 233 citations Richard C. Boucher profile →
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor

2022 165 citations Kenichi Okuda, Richard C. Boucher et al. profile →
Physiology and pathophysiology of human airway mucus

2022 159 citations David B. Hill, Brian Button et al. Physiological Reviews profile →

Peers

Countries citing papers authored by Richard C. Boucher

Since Specialization

Citations

This map shows the geographic impact of Richard C. Boucher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard C. Boucher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard C. Boucher more than expected).

Fields of papers citing papers by Richard C. Boucher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard C. Boucher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard C. Boucher. The network helps show where Richard C. Boucher may publish in the future.

Co-authorship network of co-authors of Richard C. Boucher

This figure shows the co-authorship network connecting the top 25 collaborators of Richard C. Boucher. A scholar is included among the top collaborators of Richard C. Boucher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Richard C. Boucher. Richard C. Boucher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Near fatal case of mirvetuximab soravtansine-gynx induced interstitial lung disease and a review of the primary literature 2024 ·Gynecologic Oncology Reports ·(unknown), Andrew Blake, (unknown), Richard C. Boucher, (unknown), (unknown), Benjamin B. Albright	2
2	Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection 2023 ·Journal of Theoretical Biology ·(unknown), Timothy Wessler, Alex Chen, Richard C. Boucher, Ronit Freeman, Samuel K. Lai, Raymond J. Pickles, M. Gregory Forest	5
3	Longitudinal changes in the cystic fibrosis airway microbiota with time and treatment 2023 ·Journal of Cystic Fibrosis ·G.G. Einarsson, Laura J. Sherrard, Joseph Hatch, Bryan Zorn, (unknown), Clodagh McGettigan, Katherine O’Neill, D.F. Gilpin, D.G. Downey, Michelle Murray, Gillian Lavelle, Noel G. McElvaney, Matthew C. Wolfgang, Richard C. Boucher, Marianne S. Muhlebach, Ian Bradbury, J.S. Elborn, Michael M. Tunney	2
4	Physiology and pathophysiology of human airway mucus breakdown → 2022 ·Physiological Reviews ·David B. Hill, Brian Button, Michael Rubinstein, Richard C. Boucher	159
5	Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein 2022 ·Proceedings of the National Academy of Sciences ·Yunlong Shi, Ari Zeida, Caitlin E. Edwards, Michael L. Mallory, (unknown), Matías Machado, Raymond J. Pickles, Ling Fu, Keke Liu, Jing Yang, Ralph S. Baric, Richard C. Boucher, Rafael Radí, Kate S. Carroll	30
6	An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2 2022 ·Cell Host & Microbe ·Katherine C. Barnett, Yuying Xie, Takanori Asakura, Dingka Song, Kaixin Liang, Sharon Taft-Benz, Haitao Guo, Shuangshuang Yang, Kenichi Okuda, Rodney C. Gilmore, (unknown), Thomas H. Oguin, Gregory D. Sempowski, Scott H. Randell, Mark T. Heise, Yu L. Lei, Richard C. Boucher, Jenny P.‐Y. Ting	40
7	Purinergic receptors in airway hydration 2021 ·Biochemical Pharmacology ·Eduardo R. Lazarowski, Richard C. Boucher	15
8	Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis 2019 ·Journal of Cystic Fibrosis ·Laura J. Sherrard, G.G. Einarsson, (unknown), Katherine O’Neill, L. McIlreavey, Stephanie McGrath, D.F. Gilpin, D.G. Downey, Alastair Reid, Noel G. McElvaney, Richard C. Boucher, Marianne S. Muhlebach, J.S. Elborn, Michael M. Tunney	14
9	Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1–Like Ocular Disease in Mice 2017 ·American Journal Of Pathology ·Dongfang Yu, Yogesh Saini, Gang Chen, Andrew J. Ghio, Hong Dang, Kimberlie A. Burns, Yang Wang, Richard M. Davis, Scott H. Randell, Charles R. Esther, Friedrich Paulsen, Richard C. Boucher	13
10	Allergic asthma is distinguished by sensitivity of allergen-specific CD4 ⁺ T cells and airway structural cells to type 2 inflammation 2016 ·Science Translational Medicine ·(unknown), Morris Ling, David C. Adams, Lucas Faustino, Sabina A. Islam, Roshi Afshar, Jason W. Griffith, R. Scott Harris, Aylwin Ng, Giorgia Radicioni, Amina A. Ford, (unknown), Ramnik J. Xavier, William W. Kwok, Richard C. Boucher, James Moon, Daniel L. Hamilos, Mehmet Kesımer, Melissa J. Suter, Benjamin D. Medoff, Andrew D. Luster	46
11	Culture of Human Nasal Epithelial Cells on Collagen Matrix Supports 2015 ·American Review of Respiratory Disease ·James R. Yankaskas, Calvin U. Cotton, Michael R. Knowles, John T. Gatzy, Richard C. Boucher	0
12	Growth and Differentiation of Human Nasal Epithelial Cells in Culture 2015 ·American Review of Respiratory Disease ·Reen Wu, James R. Yankaskas, E. Cheng, Michael R. Knowles, Richard C. Boucher	1
13	A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia breakdown → 2012 ·Science ·Brian Button, (unknown), Camille Ehré, Mehmet Kesımer, David B. Hill, John K. Sheehan, Richard C. Boucher, Michael Rubinstein	615
14	Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients breakdown → 2002 ·Journal of Clinical Investigation ·Dieter Worlitzsch, Robert Tarran, Martina Ulrich, Ute Schwab, (unknown), Keith C. Meyer, P. Birrer, G. Bellon, Jürgen Berger, Tilo Weiß, K Botzenhart, James R. Yankaskas, Scott H. Randell, Richard C. Boucher, Gerd Döring	778
15	Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients breakdown → 2002 ·Journal of Clinical Investigation ·Dieter Worlitzsch, Robert Tarran, Martina Ulrich, Ute Schwab, (unknown), Keith C. Meyer, P. Birrer, G. Bellon, Jürgen Berger, Tilo Weiß, K Botzenhart, James R. Yankaskas, Scott H. Randell, Richard C. Boucher, Gerd Döring	919
16	Mucus clearance as a primary innate defense mechanism for mammalian airways 2002 ·Journal of Clinical Investigation ·Michael R. Knowles, Richard C. Boucher	68
17	Mucus clearance as a primary innate defense mechanism for mammalian airways breakdown → 2002 ·Journal of Clinical Investigation ·Michael R. Knowles, Richard C. Boucher	800
18	A bacterial cell to cell signal in the lungs of cystic fibrosis patients 2002 ·FEMS Microbiology Letters ·David N. Collier, Lisa Anderson, Susan L. McKnight, Terry L. Noah, Michael R. Knowles, Richard C. Boucher, Ute Schwab, Peter H. Gilligan, Everett C. Pesci	153
19	Effect of Uridine 5'-Triphosphate Plus Amiloride on Mucociliary Clearance in Adult Cystic Fibrosis 1996 ·American Journal of Respiratory and Critical Care Medicine ·William D. Bennett, K.N. Olivier, Kirby L. Zeman, (unknown), Richard C. Boucher, Michael R. Knowles	131
20	Modulation of nasal epithelial ion permeability in normal and cystic fibrosis subjects in vivo 1983 ·Clinical research ·Martyn Knowles, J. T. Gatzy, Richard C. Boucher	2

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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