Nico van Rooijen

104.5k total citations · 30 hit papers
838 papers, 80.5k citations indexed

About

Nico van Rooijen is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Nico van Rooijen has authored 838 papers receiving a total of 80.5k indexed citations (citations by other indexed papers that have themselves been cited), including 436 papers in Immunology, 195 papers in Molecular Biology and 116 papers in Epidemiology. Recurrent topics in Nico van Rooijen's work include Immunotherapy and Immune Responses (142 papers), Immune Response and Inflammation (129 papers) and Immune Cell Function and Interaction (110 papers). Nico van Rooijen is often cited by papers focused on Immunotherapy and Immune Responses (142 papers), Immune Response and Inflammation (129 papers) and Immune Cell Function and Interaction (110 papers). Nico van Rooijen collaborates with scholars based in Netherlands, United States and Germany. Nico van Rooijen's co-authors include A.F. Sanders, Ria van Nieuwmegen, N. Kors, Gwendalyn J. Randolph, Irving L. Weissman, Ravindra Majeti, Siddhartha Jaiswal, Mark P. Chao, Wendy W. Pang and Georg Kraal and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Nico van Rooijen

835 papers receiving 79.2k citations

Hit Papers

Inflammatory monocytes re... 1994 2026 2004 2015 2007 1994 2009 2009 2007 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    2007 1.5k citations Nico van Rooijen et al. The Journal of Experimental Medicine profile →
  2. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications
    1994 1.5k citations Nico van Rooijen et al. profile →
  3. CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
    2009 1.3k citations Nico van Rooijen et al. profile →
  4. CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis
    2009 1.2k citations Nico van Rooijen et al. profile →
  5. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
    2007 1.1k citations Nico van Rooijen et al. profile →
  6. Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of T H 2 Inflammation
    2011 1.0k citations Nico van Rooijen et al. Science profile →
  7. Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response
    2004 890 citations Nico van Rooijen et al. profile →
  8. Local proliferation dominates lesional macrophage accumulation in atherosclerosis
    2013 779 citations Nico van Rooijen et al. profile →
  9. Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
    2012 757 citations Nico van Rooijen et al. Proceedings of the National Academy of Sciences profile →
  10. Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis
    2011 690 citations Nico van Rooijen et al. profile →
  11. Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation
    2013 674 citations Nico van Rooijen et al. Blood profile →
  12. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
    2007 655 citations Nico van Rooijen et al. Nature profile →
  13. Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels
    2007 633 citations Nico van Rooijen et al. profile →
  14. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
    2011 625 citations Andrew Chow, Daniel Lucas et al. The Journal of Experimental Medicine profile →
  15. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
    2010 622 citations Nico van Rooijen et al. Blood profile →
  16. Chitin induces accumulation in tissue of innate immune cells associated with allergy
    2007 597 citations Nico van Rooijen et al. Nature profile →
  17. Microglia Promote the Death of Developing Purkinje Cells
    2004 594 citations Nico van Rooijen et al. profile →
  18. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
    2012 582 citations Nico van Rooijen et al. profile →
  19. IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation
    2009 579 citations Nico van Rooijen et al. profile →
  20. Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages
    2005 574 citations Nico van Rooijen et al. profile →
  21. Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis
    2007 567 citations Nico van Rooijen et al. profile →
  22. Depletion of Hematogenous Macrophages Promotes Partial Hindlimb Recovery and Neuroanatomical Repair after Experimental Spinal Cord Injury
    1999 566 citations Nico van Rooijen et al. profile →
  23. Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes
    2013 564 citations Nico van Rooijen et al. profile →
  24. The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
    2010 538 citations Nico van Rooijen et al. profile →
  25. Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
    2013 535 citations Nico van Rooijen, Paul S. Frenette et al. profile →
  26. Control of TH17 cells occurs in the small intestine
    2011 505 citations Enric Esplugues, Samuel Huber et al. Nature profile →
  27. NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ
    2007 503 citations Nico van Rooijen et al. profile →
  28. Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer
    2008 500 citations Simon N. Waddington, John H. McVey et al. profile →
  29. Macrophages in bone fracture healing: Their essential role in endochondral ossification
    2015 482 citations Nico van Rooijen et al. profile →
  30. Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2
    2012 413 citations Nico van Rooijen et al. American Journal of Physiology-Gastrointestinal and Liver Physiology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Nico van Rooijen Netherlands 146 38.1k 21.4k 13.1k 10.0k 8.1k 838 80.5k
Charles A. Dinarello United States 174 47.0k 1.2× 36.8k 1.7× 15.9k 1.2× 11.9k 1.2× 10.8k 1.3× 873 108.0k
Siamon Gordon United Kingdom 133 41.2k 1.1× 22.0k 1.0× 10.6k 0.8× 6.7k 0.7× 4.9k 0.6× 455 78.1k
Kiyoshi Takeda Japan 118 57.1k 1.5× 27.9k 1.3× 14.7k 1.1× 9.7k 1.0× 5.4k 0.7× 463 92.8k
Ruslan Medzhitov United States 114 61.3k 1.6× 27.9k 1.3× 13.4k 1.0× 7.3k 0.7× 4.8k 0.6× 227 97.2k
Yoichiro Iwakura Japan 126 32.8k 0.9× 18.2k 0.8× 8.7k 0.7× 7.8k 0.8× 4.5k 0.6× 694 61.6k
Dan R. Littman United States 150 56.0k 1.5× 30.6k 1.4× 8.0k 0.6× 13.8k 1.4× 5.6k 0.7× 345 98.4k
Anthony Cerami United States 135 20.7k 0.5× 18.8k 0.9× 10.8k 0.8× 6.5k 0.7× 4.7k 0.6× 514 76.7k
Jürg Tschopp Switzerland 131 43.3k 1.1× 52.0k 2.4× 11.9k 0.9× 7.7k 0.8× 6.5k 0.8× 283 87.3k
Luke O'neill Ireland 124 32.5k 0.9× 23.7k 1.1× 8.3k 0.6× 4.3k 0.4× 3.5k 0.4× 392 61.3k
Christian Weber Germany 131 22.5k 0.6× 22.5k 1.1× 7.5k 0.6× 8.9k 0.9× 9.8k 1.2× 1.1k 69.1k

Countries citing papers authored by Nico van Rooijen

Since Specialization
Citations

This map shows the geographic impact of Nico van Rooijen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nico van Rooijen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nico van Rooijen more than expected).

Fields of papers citing papers by Nico van Rooijen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nico van Rooijen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nico van Rooijen. The network helps show where Nico van Rooijen may publish in the future.

Co-authorship network of co-authors of Nico van Rooijen

This figure shows the co-authorship network connecting the top 25 collaborators of Nico van Rooijen. A scholar is included among the top collaborators of Nico van Rooijen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nico van Rooijen. Nico van Rooijen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gillis, Caitlin M., Bruno Iannascoli, Ophélie Godon, et al.. (2016). IgG subclasses determine pathways of anaphylaxis in mice. Journal of Allergy and Clinical Immunology. 139(1). 269–280.e7. 70 indexed citations
2.
Shaw, Tovah N., Phillip J. Stewart-Hutchinson, Patrick Strangward, et al.. (2015). Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria. PLoS Pathogens. 11(11). e1005210–e1005210. 65 indexed citations
3.
Cha, Sung‐Jae, Kiwon Park, P. Srinivasan, et al.. (2015). CD68 acts as a major gateway for malaria sporozoite liver infection. The Journal of Experimental Medicine. 212(9). 1391–1403. 45 indexed citations
4.
Low-Marchelli, Janine M., Veronica C. Ardi, Edward A. Vizcarra, et al.. (2013). Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis. Cancer Research. 73(2). 662–671. 157 indexed citations
5.
Kamei, Akinobu, Weihui Wu, Andrew Y. Koh, et al.. (2012). Collaboration Between Macrophages and Vaccine-Induced CD4+ T Cells Confers Protection Against Lethal Pseudomonas aeruginosa Pneumonia During Neutropenia. The Journal of Infectious Diseases. 207(1). 39–49. 21 indexed citations
6.
Vinet, Jonathan, Hilmar R. J. van Weering, Annette Heinrich, et al.. (2012). Neuroprotective function for ramified microglia in hippocampal excitotoxicity. Journal of Neuroinflammation. 9(1). 27–27. 223 indexed citations
7.
Esplugues, Enric, Samuel Huber, Nicola Gagliani, et al.. (2011). Control of TH17 cells occurs in the small intestine. Nature. 475(7357). 514–518. 505 indexed citations breakdown →
8.
Soderquest, Katrina, Nick Powell, Carmelo Luci, et al.. (2011). Monocytes control natural killer cell differentiation to effector phenotypes. Blood. 117(17). 4511–4518. 72 indexed citations
9.
Gommet, Céline, Agnès Billecocq, Grégory Jouvion, et al.. (2011). Tissue Tropism and Target Cells of NSs-Deleted Rift Valley Fever Virus in Live Immunodeficient Mice. PLoS neglected tropical diseases. 5(12). e1421–e1421. 51 indexed citations
10.
Chow, Andrew, Daniel Lucas, Andrés Hidalgo, et al.. (2011). Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. The Journal of Experimental Medicine. 208(2). 261–271. 625 indexed citations breakdown →
11.
Meng, Yuru, Michael A. Beckett, Hua Liang, et al.. (2010). Blockade of Tumor Necrosis Factor α Signaling in Tumor-Associated Macrophages as a Radiosensitizing Strategy. Cancer Research. 70(4). 1534–1543. 144 indexed citations
12.
Song, Jae-Min, Nico van Rooijen, Jadranka Bozja, Richard W. Compans, & Sang‐Moo Kang. (2010). Vaccination inducing broad and improved cross protection against multiple subtypes of influenza A virus. Proceedings of the National Academy of Sciences. 108(2). 757–761. 129 indexed citations
13.
Hernandez, Lorena, Т. А. Смирнова, Dmitriy Kedrin, et al.. (2009). The EGF/CSF-1 Paracrine Invasion Loop Can Be Triggered by Heregulin β1 and CXCL12. Cancer Research. 69(7). 3221–3227. 96 indexed citations
14.
Fraccarollo, Daniela, Paolo Galuppo, Susanne Kneitz, et al.. (2008). Immediate Mineralocorticoid Receptor Blockade Improves Myocardial Infarct Healing by Modulation of the Inflammatory Response. Hypertension. 51(4). 905–914. 96 indexed citations
15.
Getts, Daniel R., Rachael Terry, Meghann Teague Getts, et al.. (2008). Ly6c+ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. The Journal of Experimental Medicine. 205(10). 2319–2337. 271 indexed citations
16.
Wakim, Linda M., Jason Waithman, Nico van Rooijen, William R. Heath, & Francis R. Carbone. (2008). Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues. Science. 319(5860). 198–202. 357 indexed citations
17.
Parker, Alan L., Simon N. Waddington, Suzanne M. K. Buckley, et al.. (2008). Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer. Journal of Virology. 83(1). 479–483. 66 indexed citations
18.
Campion, Sarah N., Rachel M. Johnson, Lauren M. Aleksunes, et al.. (2008). Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function. American Journal of Physiology-Gastrointestinal and Liver Physiology. 295(2). G294–G304. 50 indexed citations
19.
Robinson-Smith, Toni M., Idit Isaacsohn, Carol A. Mercer, et al.. (2007). Macrophages Mediate Inflammation-Enhanced Metastasis of Ovarian Tumors in Mice. Cancer Research. 67(12). 5708–5716. 165 indexed citations
20.
Rooijen, Nico van. (1975). Immune complexes in the spleen. Replacement of immune complexes trapped in spleen follicles by new immune complexes from the circulation.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 49(6). 754–62. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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