Yu L. Lei

10.7k total citations · 4 hit papers
92 papers, 7.9k citations indexed

About

Yu L. Lei is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Yu L. Lei has authored 92 papers receiving a total of 7.9k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Immunology, 32 papers in Oncology and 31 papers in Molecular Biology. Recurrent topics in Yu L. Lei's work include interferon and immune responses (27 papers), Cancer Immunotherapy and Biomarkers (18 papers) and Immune Cell Function and Interaction (17 papers). Yu L. Lei is often cited by papers focused on interferon and immune responses (27 papers), Cancer Immunotherapy and Biomarkers (18 papers) and Immune Cell Function and Interaction (17 papers). Yu L. Lei collaborates with scholars based in United States, China and Germany. Yu L. Lei's co-authors include Jenny P.‐Y. Ting, Haitao Wen, Denis Gris, Lu Zhang, W. June Brickey, Max T. Huang, Sushmita Jha, Yousuke Takahama, Joseph A. Duncan and Jenny P.‐Y. Ting and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Yu L. Lei

88 papers receiving 7.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

2011 1.4k citations Haitao Wen, Yu L. Lei et al. Nature Immunology profile →
Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy

2021 597 citations Xiaoqi Sun, Kyong Soo Park et al. profile →
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

2020 459 citations Naohiro Inohara, Yu L. Lei et al. profile →
Strategies for the development of metalloimmunotherapies

2024 95 citations Xiaoqi Sun, Xingwu Zhou et al. profile →

Peers

Countries citing papers authored by Yu L. Lei

Since Specialization

Citations

This map shows the geographic impact of Yu L. Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yu L. Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yu L. Lei more than expected).

Fields of papers citing papers by Yu L. Lei

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yu L. Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yu L. Lei. The network helps show where Yu L. Lei may publish in the future.

Co-authorship network of co-authors of Yu L. Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Yu L. Lei. A scholar is included among the top collaborators of Yu L. Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yu L. Lei. Yu L. Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Type I interferon protects against bone loss in periodontitis by mitigating an interleukin (IL)-17-neutrophil axis 2025 ·Life Sciences ·Jinmei Zhang, (unknown), (unknown), Maoxuan Lin, Ning Yu, Kevin Moss, (unknown), Di Miao, Julie T. Marchesan, Erliang Zeng, (unknown), (unknown), Yu L. Lei, Shaoping Zhang	3
2	Unraveling the mechanisms of propofol-induced psychological dependence: a multi-omics approach linked to gut microbiota in hippocampal function 2025 ·Frontiers in Medicine ·(unknown), (unknown), Yu L. Lei, (unknown), Yuxin Lin, (unknown), Qiong Wu, Shoude Zhang, Haiyan Wang	0
3	Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections 2025 ·Frontiers in Cellular and Infection Microbiology ·(unknown), Yu L. Lei, (unknown), (unknown), (unknown), Degang Yang, Feng Gao, Jianjun Li	1
4	Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways 2025 ·Cell Stress and Chaperones ·Yu L. Lei, (unknown), (unknown), Jia Hua, Wenzhi Ma	1
5	STING-activating cyclic dinucleotide-manganese nanoparticles evoke robust immunity against acute myeloid leukemia 2024 ·Journal of Controlled Release ·Marisa Aikins, Xiaoqi Sun, Hannah E. Dobson, Xingwu Zhou, Yao Xu, Yu L. Lei, James J. Moon	9
6	Microbiota-dependent activation of CD4 ⁺ T cells induces CTLA-4 blockade–associated colitis via Fcγ receptors 2024 ·Science ·Bernard C. Lo, Ilona Kryczek, Jiali Yu, Linda Vatan, Roberta Caruso, Masanori Matsumoto, Yosuke Sato, Michael H. Shaw, Naohiro Inohara, Yuying Xie, Yu L. Lei, Weiping Zou, Gabriel Núñez	40
7	Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications 2024 ·ACS Nano ·Xiaoqi Sun, Xuehui Huang, Kyong Soo Park, Xingwu Zhou, Andrew A. Kennedy, Carla D. Pretto, Qi Wu, (unknown), Yao Xu, Wang Gong, Jonathan Z. Sexton, Andrew W. Tai, Yu L. Lei, James J. Moon	39
8	Deep Learning in Single-cell Analysis 2024 ·ACM Transactions on Intelligent Systems and Technology ·(unknown), (unknown), (unknown), (unknown), Hongzhi Wen, Yixin Wang, (unknown), Wei Jin, (unknown), (unknown), Patrick Danaher, Robert Yang, Yu L. Lei, Yuying Xie, Jiliang Tang	8
9	STING agonist-loaded mesoporous manganese-silica nanoparticles for vaccine applications 2023 ·Journal of Controlled Release ·Cheng Xu, Hannah E. Dobson, Mengjie Yu, Wang Gong, Xiaoqi Sun, Kyong Soo Park, Andrew Kennedy, Xingwu Zhou, Jin Xu, Yao Xu, Andrew W. Tai, Yu L. Lei, James J. Moon	37
10	Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING 2023 ·Cell Reports ·Blake R. Heath, Wang Gong, (unknown), (unknown), Kohei Okuyama, (unknown), (unknown), Zackary R. Fitzsimonds, (unknown), Yuesong Wu, Shaoping Zhang, Haitao Wen, Steven B. Chinn, Eric Bartee, Yuying Xie, James J. Moon, Yu L. Lei	19
11	Dendrobium officinale aqueous extract influences the immune response following vaccination against SARS-CoV-2 2023 ·Biomedicine & Pharmacotherapy ·Xiaoping Gao, Ting Ye, Yu L. Lei, Qi Zhang, (unknown), Haiyan Yang, (unknown), Wen Zhou, Qinglian Wen, Jingbo Liu, Xiong Hong, (unknown)	5
12	SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling 2022 ·Nature Immunology ·Bao Zhao, (unknown), Anjun Ma, Jianwen Chen, Maria Velegraki, Hong Dong, Zihao Liu, Lingling Wang, Tamio Okimoto, (unknown), Yu L. Lei, Meixiao Long, Kenneth J. Oestreich, Qin Ma, Gang Xin, David P. Carbone, Kai He, Zihai Li, Haitao Wen	18
13	An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2 2022 ·Cell Host & Microbe ·Katherine C. Barnett, Yuying Xie, Takanori Asakura, Dingka Song, Kaixin Liang, Sharon Taft-Benz, Haitao Guo, Shuangshuang Yang, Kenichi Okuda, Rodney C. Gilmore, (unknown), Thomas H. Oguin, Gregory D. Sempowski, Scott H. Randell, Mark T. Heise, Yu L. Lei, Richard C. Boucher, Jenny P.‐Y. Ting	40
14	Supervised capacity preserving mapping: a clustering guided visualization method for scRNA-seq data 2022 ·Bioinformatics ·(unknown), Yu L. Lei, Rongrong Wang, Yuying Xie	7
15	Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy 2019 ·Cancer Research ·Qiang Zhang, Michael D. Green, Xueting Lang, Jenny Lazarus, Joshua D. Parsels, Shuang Wei, Leslie A. Parsels, Jiaqi Shi, Nithya Ramnath, Daniel Wahl, Marina Pasca di Magliano, Timothy L. Frankel, Ilona Kryczek, Yu L. Lei, Theodore S. Lawrence, Weiping Zou, Meredith A. Morgan	150
16	Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine 2018 ·Clinical Cancer Research ·Yee Sun Tan, Kanokwan Sansanaphongpricha, Yuying Xie, Christopher R. Donnelly, Xiaobo Luo, Blake R. Heath, Xinyi Zhao, Emily L. Bellile, Hongxiang Hu, Hongwei Chen, Peter J. Polverini, Qianming Chen, Simon Young, Thomas E. Carey, Jacques E. Nör, Robert L. Ferris, Gregory T. Wolf, Duxin Sun, Yu L. Lei	124
17	PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer 2017 ·Cancer Research ·Benjamin Kansy, Fernando Concha‐Benavente, Raghvendra M. Srivastava, (unknown), Gulidanna Shayan, Yu L. Lei, Jessica Moskovitz, Jennifer Moy, Jing Li, Sven Brandau, Stephan Lang, Nicole C. Schmitt, Gordon J. Freeman, William E. Gooding, D.A. Clump, Robert L. Ferris	174
18	Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer 2015 ·Cancer Research ·Fernando Concha‐Benavente, Raghvendra M. Srivastava, Sumita Trivedi, Yu L. Lei, Uma Chandran, Raja R. Seethala, Gordon J. Freeman, Robert L. Ferris	253
19	PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment 2014 ·Cancer Research ·Jing Li, (unknown), Yu L. Lei, Neil Gildener‐Leapman, Sumita Trivedi, Anthony R. Green, Larry Kane, Robert L. Ferris	181
20	Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer 2014 ·Clinical Cancer Research ·Patrick J. Schuler, Malgorzata Harasymczuk, Carmen Visús, Albert B. DeLeo, Sumita Trivedi, Yu L. Lei, Athanassios Argiris, William E. Gooding, Lisa H. Butterfield, Theresa L. Whiteside, Robert L. Ferris	120

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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