Yu L. Lei

10.7k total citations · 4 hit papers
92 papers, 7.9k citations indexed

About

Yu L. Lei is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Yu L. Lei has authored 92 papers receiving a total of 7.9k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Immunology, 32 papers in Oncology and 31 papers in Molecular Biology. Recurrent topics in Yu L. Lei's work include interferon and immune responses (27 papers), Cancer Immunotherapy and Biomarkers (18 papers) and Immune Cell Function and Interaction (17 papers). Yu L. Lei is often cited by papers focused on interferon and immune responses (27 papers), Cancer Immunotherapy and Biomarkers (18 papers) and Immune Cell Function and Interaction (17 papers). Yu L. Lei collaborates with scholars based in United States, China and Germany. Yu L. Lei's co-authors include Jenny P.‐Y. Ting, Haitao Wen, Denis Gris, Lu Zhang, W. June Brickey, Max T. Huang, Sushmita Jha, Yousuke Takahama, Joseph A. Duncan and Jenny P.‐Y. Ting and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Yu L. Lei

88 papers receiving 7.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

2011 1.4k citations Haitao Wen, Yu L. Lei et al. Nature Immunology profile →
Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy

2021 597 citations Xiaoqi Sun, Kyong Soo Park et al. profile →
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

2020 459 citations Naohiro Inohara, Yu L. Lei et al. profile →
Strategies for the development of metalloimmunotherapies

2024 95 citations Xiaoqi Sun, Xingwu Zhou et al. profile →

Peers

Yu L. Lei

IMMUN

ONCOL

EPIDE

Lu Zhang China

Jenny P.‐Y. Ting United States

Xiaojing Ma United States

Bo Huang China

Cord Sunderkötter Germany

Oscar R. Colegio United States

Shengjun Wang China

Riitta Lahesmaa Finland

Wei Zhao China

Yuzhang Wu China

Lu Zhang China

Yu L. Lei

3.4k ×0.9

IMMUN

4.1k ×1.2

994 ×0.6

ONCOL

1.4k ×1.2

EPIDE

910 ×1.4

Citations per year, relative to Yu L. Lei Yu L. Lei (= 1×) peers Lu Zhang

Countries citing papers authored by Yu L. Lei

Since Specialization

Citations

This map shows the geographic impact of Yu L. Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yu L. Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yu L. Lei more than expected).

Fields of papers citing papers by Yu L. Lei

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yu L. Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yu L. Lei. The network helps show where Yu L. Lei may publish in the future.

Co-authorship network of co-authors of Yu L. Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Yu L. Lei. A scholar is included among the top collaborators of Yu L. Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yu L. Lei. Yu L. Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zhang, Jinmei, Maoxuan Lin, Ning Yu, et al.. (2025). Type I interferon protects against bone loss in periodontitis by mitigating an interleukin (IL)-17-neutrophil axis. Life Sciences. 371. 123559–123559. 3 indexed citations

Lei, Yu L., et al.. (2025). Unraveling the mechanisms of propofol-induced psychological dependence: a multi-omics approach linked to gut microbiota in hippocampal function. Frontiers in Medicine. 12. 1539467–1539467.

Lei, Yu L., et al.. (2025). Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections. Frontiers in Cellular and Infection Microbiology. 15. 1512891–1512891. 1 indexed citations

Lei, Yu L., et al.. (2025). Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways. Cell Stress and Chaperones. 30(4). 100078–100078. 1 indexed citations

Aikins, Marisa, Xiaoqi Sun, Hannah E. Dobson, et al.. (2024). STING-activating cyclic dinucleotide-manganese nanoparticles evoke robust immunity against acute myeloid leukemia. Journal of Controlled Release. 368. 768–779. 9 indexed citations

Lo, Bernard C., Ilona Kryczek, Jiali Yu, et al.. (2024). Microbiota-dependent activation of CD4 ⁺ T cells induces CTLA-4 blockade–associated colitis via Fcγ receptors. Science. 383(6678). 62–70. 40 indexed citations

Sun, Xiaoqi, Xuehui Huang, Kyong Soo Park, et al.. (2024). Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications. ACS Nano. 18(15). 10439–10453. 39 indexed citations

Wen, Hongzhi, Yixin Wang, Wei Jin, et al.. (2024). Deep Learning in Single-cell Analysis. ACM Transactions on Intelligent Systems and Technology. 15(3). 1–62. 8 indexed citations

Xu, Cheng, Hannah E. Dobson, Mengjie Yu, et al.. (2023). STING agonist-loaded mesoporous manganese-silica nanoparticles for vaccine applications. Journal of Controlled Release. 357. 84–93. 37 indexed citations

10.

Heath, Blake R., Wang Gong, Kohei Okuyama, et al.. (2023). Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING. Cell Reports. 42(4). 112303–112303. 19 indexed citations

11.

Gao, Xiaoping, Ting Ye, Yu L. Lei, et al.. (2023). Dendrobium officinale aqueous extract influences the immune response following vaccination against SARS-CoV-2. Biomedicine & Pharmacotherapy. 162. 114702–114702. 5 indexed citations

12.

Zhao, Bao, Anjun Ma, Jianwen Chen, et al.. (2022). SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling. Nature Immunology. 23(11). 1588–1599. 18 indexed citations

13.

Barnett, Katherine C., Yuying Xie, Takanori Asakura, et al.. (2022). An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2. Cell Host & Microbe. 31(2). 243–259.e6. 40 indexed citations

14.

Lei, Yu L., et al.. (2022). Supervised capacity preserving mapping: a clustering guided visualization method for scRNA-seq data. Bioinformatics. 38(9). 2496–2503. 7 indexed citations

15.

Zhang, Qiang, Michael D. Green, Xueting Lang, et al.. (2019). Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy. Cancer Research. 79(15). 3940–3951. 150 indexed citations

16.

Tan, Yee Sun, Kanokwan Sansanaphongpricha, Yuying Xie, et al.. (2018). Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine. Clinical Cancer Research. 24(17). 4242–4255. 124 indexed citations

17.

Kansy, Benjamin, Fernando Concha‐Benavente, Raghvendra M. Srivastava, et al.. (2017). PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer. Cancer Research. 77(22). 6353–6364. 174 indexed citations

18.

Concha‐Benavente, Fernando, Raghvendra M. Srivastava, Sumita Trivedi, et al.. (2015). Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer. Cancer Research. 76(5). 1031–1043. 253 indexed citations

19.

Li, Jing, Yu L. Lei, Neil Gildener‐Leapman, et al.. (2014). PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment. Cancer Research. 75(3). 508–518. 181 indexed citations

20.

Schuler, Patrick J., Malgorzata Harasymczuk, Carmen Visús, et al.. (2014). Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer. Clinical Cancer Research. 20(9). 2433–2444. 120 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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