Brian Button

5.2k citations

63 papers · 3.5k indexed · 2 hit papers · h-index 28

Impact in

Pulmonary and Respiratory Medicine top 0.5%
- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Inhalation and Respiratory Drug Delivery
- Tracheal and airway disorders
Pharmaceutical Science top 2%
- Advanced Drug Delivery Systems

Papers in ⓘ

Pulmonary and Respiratory Medicine 49
- Cystic Fibrosis Research Advances 42
- Neonatal Respiratory Health Research 28
- Tracheal and airway disorders 18
- Inhalation and Respiratory Drug Delivery 13
Physiology 4
- Asthma and respiratory diseases 6

Co-authors: Richard C. Boucher (31 shared papers)David B. Hill (11 shared papers)Michael Rubinstein (6 shared papers)Mehmet Kesımer (6 shared papers)Robert Tarran (6 shared papers)Camille Ehré (4 shared papers)John K. Sheehan (2 shared papers)Maryse Picher (6 shared papers)
Journals: American Journal of Physiology-Lung Cellular and Molecular Physiology (5 papers)Journal of Biological Chemistry (3 papers)Proceedings of the National Academy of Sciences (3 papers)Journal of Cystic Fibrosis (3 papers)European Respiratory Journal (2 papers)
Partner nations: United States Australia United Kingdom

In The Last Decade

Brian Button

59 papers receiving 3.4k citations

Hit Papers

align trajectories log scale

Physiology and pathophysiology of human airway mucus 2022 · 159 citations

Peers

Countries citing papers authored by Brian Button

Since Specialization

Citations

This map shows the geographic impact of Brian Button's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian Button with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian Button more than expected).

Fields of papers citing papers by Brian Button

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian Button. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian Button. The network helps show where Brian Button may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian Button, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian Button Line = papers co-authored together Brian Button links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 63 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia Science ·Brian Button, Li-Heng Cai, Camille Ehré, Mehmet Kesımer, David B. Hill, John K. Sheehan, Richard C. Boucher, Michael Rubinstein Hit paper breakdown →	2012	615
2	Normal and Cystic Fibrosis Airway Surface Liquid Homeostasis Journal of Biological Chemistry ·Robert Tarran, Brian Button, Maryse Picher, Anthony M. Paradiso, Carla M. P. Ribeiro, Eduardo R. Lazarowski, Liqun Zhang, Peter L. Collins, Raymond J. Pickles, Jeffrey J. Fredberg, Richard C. Boucher	2005	272
3	Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure Journal of Clinical Investigation ·Ashley G. Henderson, Camille Ehré, Brian Button, Lubna H. Abdullah, Li-Heng Cai, Margaret W. Leigh, Genevieve DeMaria, Hiro Matsui, Scott H. Donaldson, C. William Davis, John K. Sheehan, Richard C. Boucher, Mehmet Kesımer	2014	244
4	REGULATION OF NORMAL AND CYSTIC FIBROSIS AIRWAY SURFACE LIQUID VOLUME BY PHASIC SHEAR STRESS Annual Review of Physiology ·Robert Tarran, Brian Button, Richard C. Boucher	2005	183
5	A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms Proceedings of the National Academy of Sciences ·Hirotoshi Matsui, Victoria Wagner, David B. Hill, Ute Schwab, Troy D. Rogers, Brian Button, Russell M. Taylor, Richard Superfine, Michael Rubinstein, Barbara H. Iglewski, Richard C. Boucher	2006	174
6	Physiology and pathophysiology of human airway mucus Physiological Reviews ·David B. Hill, Brian Button, Michael Rubinstein, Richard C. Boucher Hit paper breakdown →	2022	159
7	CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium PLoS Biology ·Liqun Zhang, Brian Button, Sherif E. Gabriel, Susan E. Burkett, Yu Yan, Mario H. Skiadopoulos, Yan L. Dang, Leatrice Vogel, Tristan R. McKay, April Mengos, Richard C. Boucher, Peter L. Collins, Raymond J. Pickles	2009	147
8	Role of mechanical stress in regulating airway surface hydration and mucus clearance rates Respiratory Physiology & Neurobiology ·Brian Button, Richard C. Boucher	2008	129
9	Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia The Journal of Physiology ·Brian Button, Maryse Picher, Richard C. Boucher	2007	125
10	The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis American Journal of Respiratory and Critical Care Medicine ·Wayne H. Anderson, Raymond D. Coakley, Brian Button, Ashley G. Henderson, Kirby L. Zeman, Neil E. Alexis, David B. Peden, Eduardo R. Lazarowski, C. William Davis, Summer Bailey, Fred Fuller, Martha Almond, Bahjat F. Qaqish, Elena Bordonali, Michael Rubinstein, William D. Bennett, Mehmet Kesımer, Richard C. Boucher	2015	113
11	Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH European Respiratory Journal ·David B. Hill, Robert F. Long, William J. Kissner, Eyad Atieh, Ian C. Garbarine, Matthew R. Markovetz, Nicholas C. Fontana, Matthew Christy, Mehdi Habibpour, Robert Tarran, M. Gregory Forest, Richard C. Boucher, Brian Button	2018	94
12	Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways Science Signaling ·Brian Button, Seiko F. Okada, C. Brandon Frederick, William R. Thelin, Richard C. Boucher	2013	90
13	IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis Journal of Clinical Investigation ·Gang Chen, Ling Sun, Takafumi Kato, Kenichi Okuda, Mary B. Martino, Aiman Abzhanova, Jennifer Lin, Rodney C. Gilmore, Bethany D. Batson, Yvonne K. O’Neal, A.S. Volmer, Hong Dang, Yangmei Deng, Scott H. Randell, Brian Button, Alessandra Livraghi-Butrico, Mehmet Kesımer, Carla M. P. Ribeiro, Wanda K. O’Neal, Richard C. Boucher	2019	85
14	Airway surface liquid pH is not acidic in children with cystic fibrosis Nature Communications ·André Schultz, Ramaa Puvvadi, Sergey M. Borisov, Nicole C. Shaw, Ingo Klimant, Luke J. Berry, Samuel Montgomery, Thien Nguyen, Silvia M. Kreda, Anthony Kicic, Peter B. Noble, Brian Button, Stephen M. Stick	2017	80
15	Roles of mucus adhesion and cohesion in cough clearance Proceedings of the National Academy of Sciences ·Brian Button, Henry Goodell, Eyad Atieh, Yu‐Cheng Chen, Robert T. Williams, Siddharth Shenoy, Elijah Lackey, Nathan T. Shenkute, Li-Heng Cai, Robert G. Dennis, Richard C. Boucher, Michael Rubinstein	2018	74
16	Monitoring airway mucus flow and ciliary activity with optical coherence tomography Biomedical Optics Express ·Amy L. Oldenburg, Raghav K. Chhetri, David B. Hill, Brian Button	2012	72
17	TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis American Journal of Respiratory and Critical Care Medicine ·Henry Danahay, Sarah Lilley, Roy Fox, Holly Charlton, Juan Sabater, Brian Button, Clive McCarthy, Stephen P. Collingwood, Martin Gosling	2020	65
18	Airway Surface Liquid Volume Regulation Determines Different Airway Phenotypes in Liddle Compared with βENaC-overexpressing Mice Journal of Biological Chemistry ·Marcus Mall, Brian Button, Bjarki Jóhannesson, Zhe Zhou, Alessandra Livraghi, Ray A. Caldwell, Susanne Schubert‐Bast, Carsten Schultz, Wanda K. O’Neal, Sylvain Pradervand, Edith Hümmler, Bernard C. Rossier, Barbara R. Grubb, Richard C. Boucher	2010	62
19	Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin American Journal of Physiology-Lung Cellular and Molecular Physiology ·Barbara R. Grubb, Alessandra Livraghi-Butrico, Troy D. Rogers, Weining Yin, Brian Button, Lawrence E. Ostrowski	2016	46
20	Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype. PubMed ·Brian Button, Wayne H. Anderson, Richard C. Boucher	2016	46

About Brian Button

Brian Button is a scholar working on Pulmonary and Respiratory Medicine, Physiology, Endocrine and Autonomic Systems, Emergency Medical Services and Speech and Hearing, having authored 63 papers that have together received 3.5k indexed citations. Recurring topics across this work include Cystic Fibrosis Research Advances (42 papers), Neonatal Respiratory Health Research (28 papers), Tracheal and airway disorders (18 papers), Inhalation and Respiratory Drug Delivery (13 papers), Asthma and respiratory diseases (6 papers), Pediatric health and respiratory diseases (5 papers), Neuroscience of respiration and sleep (5 papers) and Dysphagia Assessment and Management (4 papers). The work is most often cited by research in Pulmonary and Respiratory Medicine (2.3k citations), Pharmaceutical Science (186 citations), Physiology (130 citations), Emergency Medical Services (195 citations) and Endocrine and Autonomic Systems (161 citations). Brian Button has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Richard C. Boucher, David B. Hill, Michael Rubinstein, Mehmet Kesımer, Robert Tarran, Camille Ehré, John K. Sheehan, Maryse Picher, Eduardo R. Lazarowski and Raymond J. Pickles. Their work appears in journals such as American Journal of Physiology-Lung Cellular and Molecular Physiology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Journal of Cystic Fibrosis and European Respiratory Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact