Philip A. Cole

31.9k total citations · 7 hit papers
294 papers, 22.3k citations indexed

About

Philip A. Cole is a scholar working on Molecular Biology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Philip A. Cole has authored 294 papers receiving a total of 22.3k indexed citations (citations by other indexed papers that have themselves been cited), including 218 papers in Molecular Biology, 46 papers in Oncology and 23 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Philip A. Cole's work include Genomics and Chromatin Dynamics (46 papers), Ubiquitin and proteasome pathways (44 papers) and Histone Deacetylase Inhibitors Research (43 papers). Philip A. Cole is often cited by papers focused on Genomics and Chromatin Dynamics (46 papers), Ubiquitin and proteasome pathways (44 papers) and Histone Deacetylase Inhibitors Research (43 papers). Philip A. Cole collaborates with scholars based in United States, United Kingdom and Canada. Philip A. Cole's co-authors include Yang Shi, Fei Lan, Peter Mulligan, Robert A. Casero, Yujiang Geno Shi, Johnathan R. Whetstine, Dolan Sondhi, John Kuriyan, Tom W. Muir and Xuewu Zhang and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Philip A. Cole

290 papers receiving 22.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

2004 3.2k citations Philip A. Cole et al. profile →
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

2006 1.2k citations Philip A. Cole et al. profile →
Expressed protein ligation: A general method for protein engineering

1998 957 citations Philip A. Cole et al. Proceedings of the National Academy of Sciences profile →
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

2010 732 citations Chandrani Mukherjee, David J. Meyers et al. profile →
Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

2010 504 citations Erin M. Bowers, Chandrani Mukherjee et al. profile →
Protein Lysine Acetylation by p300/CBP

2015 414 citations Philip A. Cole et al. profile →
Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

2024 79 citations Philip A. Cole, Yingming Zhao et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Philip A. Cole United States	75	17.2k	4.0k	1.9k	1.6k	1.5k	294	22.3k
Stanley T. Crooke United States	83	17.8k 1.0×	4.0k 1.0×	1.6k 0.8×	2.3k 1.4×	2.4k 1.6×	415	25.7k
Doriano Fabbro Switzerland	74	12.4k 0.7×	3.7k 0.9×	799 0.4×	1.8k 1.1×	1.4k 0.9×	223	20.3k
Lorenzo A. Pinna Italy	74	15.9k 0.9×	3.4k 0.8×	1.6k 0.8×	1.3k 0.8×	757 0.5×	448	21.6k
E. Premkumar Reddy United States	63	10.4k 0.6×	4.8k 1.2×	2.1k 1.1×	1.0k 0.6×	2.1k 1.4×	203	17.2k
Alexander Levitzki Israel	74	14.3k 0.8×	5.9k 1.5×	960 0.5×	1.7k 1.0×	1.8k 1.2×	328	22.3k
Stefan Knapp Germany	91	21.6k 1.3×	5.6k 1.4×	1.4k 0.7×	3.7k 2.2×	1.1k 0.7×	516	29.0k
Susan S. Taylor United States	98	29.1k 1.7×	3.5k 0.9×	2.0k 1.1×	1.4k 0.8×	1.1k 0.7×	462	35.7k
Philip D. Jeffrey United States	59	14.8k 0.9×	6.0k 1.5×	1.5k 0.8×	764 0.5×	1.2k 0.8×	174	20.5k
Timothy D. Veenstra United States	88	17.3k 1.0×	4.2k 1.1×	2.3k 1.2×	484 0.3×	2.4k 1.5×	401	28.5k
James E. Bradner United States	86	24.1k 1.4×	6.3k 1.6×	1.5k 0.8×	1.4k 0.9×	2.3k 1.5×	217	28.8k

Countries citing papers authored by Philip A. Cole

Since Specialization

Citations

This map shows the geographic impact of Philip A. Cole's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip A. Cole with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip A. Cole more than expected).

Fields of papers citing papers by Philip A. Cole

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip A. Cole. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip A. Cole. The network helps show where Philip A. Cole may publish in the future.

Co-authorship network of co-authors of Philip A. Cole

This figure shows the co-authorship network connecting the top 25 collaborators of Philip A. Cole. A scholar is included among the top collaborators of Philip A. Cole based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip A. Cole. Philip A. Cole is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mariani, Luca, et al.. (2025). DNA bendability regulates transcription factor binding to nucleosomes. Nature Structural & Molecular Biology. 32(11). 2185–2195.

Xie, Guomin, Lin Gao, Ruifang Lu, et al.. (2025). Biochemical analysis of PD-L1 ubiquitination by CRL3SPOP, ARIH1, and NEDD4 family ubiquitin ligases. Structure. 33(8). 1304–1313.e4. 1 indexed citations

Olsen, Sarah Naomi, et al.. (2024). A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes. Proceedings of the National Academy of Sciences. 121(26). e2405905121–e2405905121. 5 indexed citations

Wyant, William Austin, et al.. (2024). p300 KAT Regulates SOX10 Stability and Function in Human Melanoma. Cancer Research Communications. 4(8). 1894–1907. 4 indexed citations

Waterbury, Amanda L., Hui Si Kwok, Allyson M. Freedy, et al.. (2024). An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular Cell. 84(12). 2238–2254.e11. 13 indexed citations

Viennet, Thibault, Eunyoung Park, Nam Chu, et al.. (2022). PH domain-mediated autoinhibition and oncogenic activation of Akt. eLife. 11. 17 indexed citations

Huang, He, Di Zhang, Yejing Weng, et al.. (2021). The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway. Science Advances. 7(9). 149 indexed citations

Soroko, Kara M., Benjamin K. Eschle, Margaret K. Wilkens, et al.. (2020). Combined Targeting of the BRD4–NUT–p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734. Molecular Cancer Therapeutics. 19(7). 1406–1414. 58 indexed citations

Chu, Nam, et al.. (2020). The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling. eLife. 9. 54 indexed citations

10.

Kim, Edward, Beth E. Zucconi, Muzhou Wu, et al.. (2019). MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma. Cancer Research. 79(10). 2649–2661. 44 indexed citations

11.

Policastro, Robert A., Shruthi Sriramkumar, Ning Ding, et al.. (2019). Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA -Mutant Colorectal Cancer. Molecular Cancer Research. 18(2). 264–277. 36 indexed citations

12.

Kalin, Jay H., Abdulkerim Eroglu, Hua Liu, et al.. (2019). Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model. PLoS ONE. 14(3). e0213095–e0213095. 12 indexed citations

13.

Mo, Gary, Brian Ross, Fabian Hertel, et al.. (2017). Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution. Nature Methods. 14(4). 427–434. 139 indexed citations

14.

Santer, Frédéric R., Su Jung Oh, Holger H.H. Erb, et al.. (2011). Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines. Molecular Cancer Therapeutics. 10(9). 1644–1655. 163 indexed citations

15.

Barnett, Brad P., Yousang Hwang, Martin S. Taylor, et al.. (2010). Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor. Science. 330(6011). 1689–1692. 212 indexed citations

16.

Reynoird, Nicolas, Brian E. Schwartz, Karin Sadoul, et al.. (2010). Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. The EMBO Journal. 29(17). 2943–2952. 142 indexed citations

17.

Kenneth, Niall S., et al.. (2007). TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. Proceedings of the National Academy of Sciences. 104(38). 14917–14922. 97 indexed citations

18.

Guidez, Fabien, Louise Howell, Mark Isalan, et al.. (2005). Histone Acetyltransferase Activity of p300 Is Required for Transcriptional Repression by the Promyelocytic Leukemia Zinc Finger Protein. Molecular and Cellular Biology. 25(13). 5552–5566. 90 indexed citations

19.

Subbaramaiah, Kotha, Philip A. Cole, & Andrew J. Dannenberg. (2002). Retinoids and carnosol suppress cyclooxygenase-2 transcription by CREB-binding protein/p300-dependent and -independent mechanisms.. PubMed. 62(9). 2522–30. 131 indexed citations

20.

Bandyopadhyay, Debdutta, et al.. (2002). Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.. PubMed. 62(21). 6231–9. 128 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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