R. Luke Wiseman

10.3k total citations · 3 hit papers
104 papers, 7.1k citations indexed

About

R. Luke Wiseman is a scholar working on Molecular Biology, Cell Biology and Epidemiology. According to data from OpenAlex, R. Luke Wiseman has authored 104 papers receiving a total of 7.1k indexed citations (citations by other indexed papers that have themselves been cited), including 81 papers in Molecular Biology, 66 papers in Cell Biology and 18 papers in Epidemiology. Recurrent topics in R. Luke Wiseman's work include Endoplasmic Reticulum Stress and Disease (58 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (23 papers) and Autophagy in Disease and Therapy (17 papers). R. Luke Wiseman is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (58 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (23 papers) and Autophagy in Disease and Therapy (17 papers). R. Luke Wiseman collaborates with scholars based in United States, United Kingdom and Canada. R. Luke Wiseman's co-authors include Jeffery W. Kelly, Evan T. Powers, Per Hammarström, T. Kelly Rainbolt, Joseph C. Genereux, Lars Plate, William E. Balch, Yoshiki Sekijima, Jaleh S. Mesgarzadeh and Lisa M. Ryno and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

R. Luke Wiseman

100 papers receiving 7.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

2012 572 citations Evan T. Powers, R. Luke Wiseman et al. Proceedings of the National Academy of Sciences profile →
Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

2013 422 citations Matthew D. Shoulders, Lisa M. Ryno et al. profile →
Reshaping endoplasmic reticulum quality control through the unfolded protein response

2022 245 citations R. Luke Wiseman et al. Molecular Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
R. Luke Wiseman United States	43	5.0k	3.1k	1.3k	1.1k	549	104	7.1k
James A. Olzmann United States	40	7.5k 1.5×	2.2k 0.7×	1.6k 1.2×	1.7k 1.5×	773 1.4×	71	12.3k
Olga Perišić United Kingdom	43	6.5k 1.3×	2.5k 0.8×	714 0.5×	625 0.6×	645 1.2×	66	8.3k
Jacek Bielawski United States	63	9.3k 1.8×	2.9k 0.9×	2.1k 1.5×	1.4k 1.3×	602 1.1×	144	11.1k
Besim Öğretmen United States	54	8.3k 1.7×	2.3k 0.7×	1.2k 0.9×	1.5k 1.3×	1.1k 2.1×	148	10.0k
Sandra L. Hofmann United States	41	3.3k 0.7×	2.0k 0.6×	2.4k 1.8×	429 0.4×	290 0.5×	101	5.9k
Alicja Bielawska United States	63	10.1k 2.0×	2.5k 0.8×	2.1k 1.6×	775 0.7×	837 1.5×	144	11.6k
Donat Kögel Germany	48	3.8k 0.8×	911 0.3×	774 0.6×	1.3k 1.2×	727 1.3×	122	5.9k
Michael Boyce United States	26	4.9k 1.0×	1.9k 0.6×	399 0.3×	1.5k 1.3×	629 1.1×	51	7.2k
Noah Dephoure United States	38	8.5k 1.7×	2.0k 0.7×	582 0.4×	729 0.6×	1.2k 2.1×	60	10.7k
Stefan J. Marciniak United Kingdom	38	4.4k 0.9×	4.3k 1.4×	893 0.7×	2.2k 1.9×	551 1.0×	119	8.7k

Countries citing papers authored by R. Luke Wiseman

Since Specialization

Citations

This map shows the geographic impact of R. Luke Wiseman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. Luke Wiseman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. Luke Wiseman more than expected).

Fields of papers citing papers by R. Luke Wiseman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. Luke Wiseman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. Luke Wiseman. The network helps show where R. Luke Wiseman may publish in the future.

Co-authorship network of co-authors of R. Luke Wiseman

This figure shows the co-authorship network connecting the top 25 collaborators of R. Luke Wiseman. A scholar is included among the top collaborators of R. Luke Wiseman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. Luke Wiseman. R. Luke Wiseman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Podojil, Joseph R., Ming‐Yi Chiang, G. Schulz, et al.. (2025). AA147 Alleviates Symptoms in a Mouse Model of Multiple Sclerosis by Reducing Oligodendrocyte Loss. Glia. 73(6). 1241–1257.

Chu, Alan, et al.. (2025). Drug repurposing screen identifies an HRI activating compound that promotes adaptive mitochondrial remodeling in MFN2-deficient cells. Proceedings of the National Academy of Sciences. 122(48). e2517552122–e2517552122.

Kim, Jisu, Hyung Ryong Moon, Yunjin Jung, et al.. (2023). Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators. Bioorganic & Medicinal Chemistry Letters. 89. 129306–129306. 2 indexed citations

Barad, Benjamin A., et al.. (2023). Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of Cell Biology. 222(4). 31 indexed citations

Rosarda, Jessica D., Sarah Giles, Sarah Harkins‐Perry, et al.. (2023). Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity. Nature Communications. 14(1). 4119–4119. 16 indexed citations

Pariollaud, Marie, Alanna B. Chan, Brian J. Altman, et al.. (2022). Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras -driven lung cancer. Science Advances. 8(39). eabo1123–eabo1123. 27 indexed citations

Chaudhary, Vidyanath, Marie Dominique Ah Kioon, Sung‐Min Hwang, et al.. (2022). Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses. The Journal of Experimental Medicine. 219(11). 42 indexed citations

Yang, Jie, Albert S. Song, R. Luke Wiseman, & Gabriel C. Lander. (2022). Cryo-EM structure of hexameric yeast Lon protease (PIM1) highlights the importance of conserved structural elements. Journal of Biological Chemistry. 298(3). 101694–101694. 9 indexed citations

Shin, Mia, Edmond R. Watson, Albert S. Song, et al.. (2021). Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nature Communications. 12(1). 3239–3239. 46 indexed citations

10.

Shin, Mia, et al.. (2020). Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. Science Advances. 6(21). eaba8404–eaba8404. 48 indexed citations

11.

Plate, Lars, Bibiana Rius, Bianca Nguyen, et al.. (2019). Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein. Cell chemical biology. 26(7). 913–925.e4. 21 indexed citations

12.

Qu, Song, Saikat Chowdhury, Joseph D. Schonhoft, et al.. (2017). The endoplasmic reticulum HSP 40 co‐chaperone ER dj3/ DNAJB 11 assembles and functions as a tetramer. The EMBO Journal. 36(15). 2296–2309. 37 indexed citations

13.

Puchades, Cristina, Anthony J. Rampello, Mia Shin, et al.. (2017). Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. Science. 358(6363). 159 indexed citations

14.

Plate, Lars, Christina B. Cooley, John J. Chen, et al.. (2016). Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. eLife. 5. 173 indexed citations

15.

Murray, Amber N., Wentao Chen, Aristotelis Antonopoulos, et al.. (2015). Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity. Chemistry & Biology. 22(8). 1052–1062. 39 indexed citations

16.

Genereux, Joseph C., Song Qu, Minghai Zhou, et al.. (2014). Unfolded protein response‐induced ER dj3 secretion links ER stress to extracellular proteostasis. The EMBO Journal. 34(1). 4–19. 99 indexed citations

17.

Ryno, Lisa M., R. Luke Wiseman, & Jeffery W. Kelly. (2013). Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases. Current Opinion in Chemical Biology. 17(3). 346–352. 63 indexed citations

18.

Wiseman, R. Luke, Yuhong Zhang, Heather P. Harding, et al.. (2010). Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1. Molecular Cell. 38(2). 291–304. 156 indexed citations

19.

Wiseman, R. Luke, Cole M. Haynes, & David Ron. (2010). SnapShot: The Unfolded Protein Response. Cell. 140(4). 590–590.e2. 39 indexed citations

20.

Sekijima, Yoshiki, R. Luke Wiseman, Jeanne Matteson, et al.. (2005). The Biological and Chemical Basis for Tissue-Selective Amyloid Disease. Cell. 121(1). 73–85. 391 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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