Alan Engelman

22.5k citations

202 papers · 16.9k indexed · 6 hit papers · h-index 74

Impact in

Virology top 0.01%
- HIV Research and Treatment
Infectious Diseases top 0.05%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in ⓘ

Virology 175
- HIV Research and Treatment 175
Infectious Diseases 129
- HIV/AIDS drug development and treatment 128
- HIV/AIDS Research and Interventions 14

Co-authors: Robert Craigie (16 shared papers)Peter Cherepanov (40 shared papers)Kenneth A. Matreyek (9 shared papers)Alison B. Hickman (5 shared papers)Kiyoshi Mizuuchi (2 shared papers)S. Hare (7 shared papers)Frederic D. Bushman (4 shared papers)Nick Vandegraaff (11 shared papers)
Journals: Journal of Virology (41 papers)Journal of Biological Chemistry (18 papers)Nucleic Acids Research (13 papers)Proceedings of the National Academy of Sciences (12 papers)PLoS Pathogens (11 papers)
Partner nations: United States United Kingdom France

In The Last Decade

Alan Engelman

199 papers receiving 16.7k citations

Hit Papers

6 papers align trajectories log scale

Haematopoietic stem and progenitor cells from human pluripotent stem cells 2017 · 337 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Nature
2015 Nature
2010 Nature
2008 Science
1994 Science
1991 Cell

Peers

Countries citing papers authored by Alan Engelman

Since Specialization

Citations

This map shows the geographic impact of Alan Engelman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Engelman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Engelman more than expected).

Fields of papers citing papers by Alan Engelman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Engelman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Engelman. The network helps show where Alan Engelman may publish in the future.

Co-authors

The 25 scholars most cited alongside Alan Engelman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alan Engelman Line = papers co-authored together Alan Engelman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 202 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen Science ·Abraham L. Brass, Derek M. Dykxhoorn, Yair Benita, Nan Yan, Alan Engelman, Ramnik J. Xavier, Judy Lieberman, Stephen J. Elledge Hit paper breakdown →	2008	1149
2	Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases Science ·Fred Dyda, Alison B. Hickman, Timothy M. Jenkins, Alan Engelman, Robert Craigie, David R. Davies Hit paper breakdown →	1994	667
3	HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer Cell ·Alan Engelman, Kiyoshi Mizuuchi, Robert Craigie Hit paper breakdown →	1991	542
4	Retroviral intasome assembly and inhibition of DNA strand transfer Nature ·S. Hare, Saumya Gupta, Eugene Valkov, Alan Engelman, Peter Cherepanov Hit paper breakdown →	2010	539
5	Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro Journal of Virology ·Alan Engelman, Robert Craigie	1992	452
6	Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication Journal of Virology ·Alan Engelman, G Englund, Jan M. Orenstein, Malcolm A. Martin, Robert Craigie	1995	372
7	LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration Genes & Development ·Ming-Chieh Shun, Nidhanapati K. Raghavendra, Nick Vandegraaff, Janet E. Daigle, Siobhan Hughes, Paul Kellam, Peter Cherepanov, Alan Engelman	2007	368
8	Haematopoietic stem and progenitor cells from human pluripotent stem cells Nature ·Ryohichi Sugimura, Deepak Kumar Jha, Areum Han, Clara Soria‐Valles, Edroaldo Lummertz da Rocha, Yi-Fen Lu, Jeremy A. Goettel, Erik Serrao, R. Grant Rowe, Mohan Malleshaiah, Irene Wong, Patricia Sousa, Ted N. Zhu, Andrea Ditadi, Gordon Keller, Alan Engelman, Scott B. Snapper, Sergei Doulatov, George Q. Daley Hit paper breakdown →	2017	337
9	Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proceedings of the National Academy of Sciences ·Peter Cherepanov, A.L.B. Ambrosio, Shaila Rahman, Tom Ellenberger, Alan Engelman	2005	325
10	Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proceedings of the National Academy of Sciences ·Frederic D. Bushman, Alan Engelman, Ira Palmer, Paul T. Wingfield, Robert Craigie	1993	316
11	Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex. The EMBO Journal ·Alan Engelman, Frederic D. Bushman, Robert Craigie	1993	305
12	Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity Nature ·James K. Nuñez, Amy S.Y. Lee, Alan Engelman, Jennifer A. Doudna Hit paper breakdown →	2015	263
13	The structural biology of HIV-1: mechanistic and therapeutic insights Nature Reviews Microbiology ·Alan Engelman, Peter Cherepanov	2012	261
14	Solution Structure of the DNA Binding Domain of HIV-1 Integrase Biochemistry ·Patricia J. Lodi, James A. Ernst, John Kuszewski, Alison B. Hickman, Alan Engelman, Robert Craigie, G. Marius Clore, Angela M. Gronenborn	1995	243
15	A Soluble Active Mutant of HIV-1 Integrase Journal of Biological Chemistry ·Timothy M. Jenkins, Alan Engelman, Rodolfo Ghirlando, Robert Craigie	1996	243
16	Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity PLoS Pathogens ·Kenneth A. Matreyek, Sara Suna Yücel, Xiang Li, Alan Engelman	2013	231
17	Identification of an Evolutionarily Conserved Domain in Human Lens Epithelium-derived Growth Factor/Transcriptional Co-activator p75 (LEDGF/p75) That Binds HIV-1 Integrase Journal of Biological Chemistry ·Peter Cherepanov, Eric Devroe, Pamela A. Silver, Alan Engelman	2004	231
18	Human Immunodeficiency Virus Type 1 cDNAs Produced in the Presence of APOBEC3G Exhibit Defects in Plus-Strand DNA Transfer and Integration Journal of Virology ·Jean L. Mbisa, Rebekah Barr, James A. Thomas, Nick Vandegraaff, Irene Dorweiler, Evguenia S. Svarovskaia, William L. Brown, Louis M. Mansky, Robert J. Gorelick, Reuben S. Harris, Alan Engelman, Vinay K. Pathak	2007	228
19	The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding Journal of Virology ·Alan Engelman, Alison B. Hickman, Robert Craigie	1994	215
20	Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 Nature Structural & Molecular Biology ·Peter Cherepanov, Zhenyu Sun, Shaila Rahman, Goedele N. Maertens, Gerhard Wagner, Alan Engelman	2005	186

About Alan Engelman

Alan Engelman is a scholar working on Virology, Infectious Diseases, Molecular Biology, Epidemiology and Genetics, having authored 202 papers that have together received 16.9k indexed citations. Recurring topics across this work include HIV Research and Treatment (175 papers), HIV/AIDS drug development and treatment (128 papers), Biochemical and Molecular Research (57 papers), Cytomegalovirus and herpesvirus research (37 papers), CRISPR and Genetic Engineering (25 papers), Virus-based gene therapy research (17 papers), RNA Research and Splicing (16 papers) and HIV/AIDS Research and Interventions (14 papers). The work is most often cited by research in Virology (11.8k citations), Infectious Diseases (9.7k citations), Molecular Biology (10.6k citations), Immunology (1.6k citations) and Epidemiology (2.5k citations). Alan Engelman has collaborated with scholars based in United States, United Kingdom and France. Frequent co-authors include Robert Craigie, Peter Cherepanov, Kenneth A. Matreyek, Alison B. Hickman, Kiyoshi Mizuuchi, S. Hare, Frederic D. Bushman, Nick Vandegraaff, Judy Lieberman and Nan Yan. Their work appears in journals such as Journal of Virology, Journal of Biological Chemistry, Nucleic Acids Research, Proceedings of the National Academy of Sciences and PLoS Pathogens.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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