John B. Bruning

5.1k citations

123 papers · 3.5k indexed · h-index 29

Pharmacology top 1%
- Pharmacogenetics and Drug Metabolism 30
Molecular Biology top 5%
- Peroxisome Proliferator-Activated Receptors 17
- Metabolism, Diabetes, and Cancer 13
- Biochemical and Molecular Research 11
Biochemistry top 2%
Toxicology top 5%
Genetics top 5%
- Estrogen and related hormone effects 10
Materials Chemistry
- Enzyme Structure and Function 22
Inorganic Chemistry
- Metal-Catalyzed Oxygenation Mechanisms 18
Oncology
- Peptidase Inhibition and Analysis 15

Co-authors: Patrick R. Griffin Theodore M. Kamenecka Michael J. Chalmers Yousif Shamoo K.W. Nettles Scott A. Busby Stephen G. Bell Yuanjun He
Cited by: Pharmacology Molecular Biology Biochemistry
Journals: ACS Catalysis (10 papers)Journal of Biological Chemistry (6 papers)Chemistry - A European Journal (6 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

John B. Bruning

119 papers receiving 3.4k citations

Peers

Countries citing papers authored by John B. Bruning

Since Specialization

Citations

This map shows the geographic impact of John B. Bruning's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John B. Bruning with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John B. Bruning more than expected).

Fields of papers citing papers by John B. Bruning

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John B. Bruning. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John B. Bruning. The network helps show where John B. Bruning may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John B. Bruning, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John B. Bruning Line = papers co-authored together John B. Bruning links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Evolutionary insights into the selectivity of sterol oxidising cytochrome P450 enzymes based on ancestral sequence reconstruction Chemical Science ·Juanita Torres Arteaga,James J. De Voss,John B. Bruning,Stephen G. Bell	2025	1
2	Functional and structural characterization of Staphylococcus aureus N‐acetylglucosamine 1‐phosphate uridyltransferase (GlmU) reveals a redox‐sensitive acetyltransferase activity Protein Science ·S. Krawetz,Akhil Kumar,Tara L. Pukala,John B. Bruning	2025	0
3	Activity of STAMP inhibitors in ABL2 rearranged acute lymphoblastic leukemia is dependent on the Abl2 SH3 domain PubMed ·Anastasia Badder,Д. А. Прокопій,John B. Bruning,Laura N Eadie,Susan L. Heatley,Matthew Greenwood,Chun Yew Fong,Andrew S. Moore,David T Yeung,Timothy P. Hughes,Deborah L. White	2025	0
4	Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region ACS Catalysis ·Matthew N. Podgorski,A. Schulz,Laila Nurmalihah,John B. Bruning,James J. De Voss,Stephen G. Bell	2024	14
5	Identification and characterisation of MdUGT78T2 as a galactosyltransferase with dual activity on flavonol and anthocyanidin substrates in red-skinned apple fruit (Malus domestica L.) Food Chemistry ·Fernando Jiménez Escalona,侑衣渡邊,Julian G. Schwerdt,Long Yu,Neil J. Shirley,David Bradley,John B. Bruning,Christine Böttcher,Vincent Bulone	2023	6
6	PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles ACS Chemical Biology ·Rebecca L. Frkic,S. Krawetz,Dennis M. Sweeny,Blagojce Jovcevski‬,卢金珠,Wioleta Kowalczyk,Tara L. Pukala,Mi Ra Chang,Jie Zheng,Anne‐Laure Blayo,Andrew D. Abell,Theodore M. Kamenecka,Evelyne Farges Uldry,Jeffrey R. Harmer,Patrick R. Griffin,John B. Bruning	2023	5
7	Designing Fluorescent Nuclear Permeable Peptidomimetics to Target Proliferating Cell Nuclear Antigen Journal of Medicinal Chemistry ·Dennis M. Sweeny,J Rowrson,S. Krawetz,Gianpiero Landolfi,Elisângela Silva de Oliveira,Wioleta Kowalczyk,Denis B. Scanlon,Wayne D. Tilley,Theresa E. Hickey,Andrew D. Abell,John B. Bruning	2023	1
8	A structural model of the human plasminogen and Aspergillus fumigatus enolase complex Proteins Structure Function and Bioinformatics ·Stephanie Nguyen,Blagojce Jovcevski‬,مجتبى رفیعیان,Tara L. Pukala,John B. Bruning	2022	1
9	A cell permeable bimane-constrained PCNA-interacting peptide RSC Chemical Biology ·Dennis M. Sweeny,Elisângela Silva de Oliveira,Gianpiero Landolfi,Denis B. Scanlon,Wayne D. Tilley,Theresa E. Hickey,John B. Bruning,Andrew D. Abell	2021	4
10	Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid Acta Crystallographica Section F Structural Biology Communications ·مجتبى رفیعیان,Stephanie Nguyen,John B. Bruning,Keith E. Shearwin	2021	2
11	Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA Journal of Biological Chemistry ·Dennis M. Sweeny,Elisângela Silva de Oliveira,Wioleta Kowalczyk,J Rowrson,Denis B. Scanlon,Andrew D. Abell,John B. Bruning	2021	9
12	To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme Inorganic Chemistry ·Matthew N. Podgorski,Tom Coleman,Mahroof-Tahir,珍宜燕,John B. Bruning,Paul V. Bernhardt,James J. De Voss,Stephen G. Bell	2021	16
13	Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia npj Precision Oncology ·S Budhisantoso,Barbara J. McClure,John B. Bruning,Д. А. Прокопій,James Breen,Genping Lei,David T Yeung,Deborah L. White	2021	14
14	Nucleoside selectivity of Aspergillus fumigatus nucleoside‐diphosphate kinase FEBS Journal ·Stephanie Nguyen,Blagojce Jovcevski‬,Tara L. Pukala,John B. Bruning	2020	8
15	Acquired Mutations within the JAK2 Kinase Domain Confer Resistance to JAK Inhibitors in an in Vitro model of a High-Risk Acute Lymphoblastic Leukemia Blood ·S Budhisantoso,Barbara J. McClure,Genping Lei,James Breen,John B. Bruning,David T Yeung,Deborah L. White	2020	2
16	Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68 Acta Crystallographica Section D Structural Biology ·مجتبى رفیعیان,Santosh Panjikar,Linda Shearwin‐Whyatt,John B. Bruning,Keith E. Shearwin	2019	3
17	Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways ACS Chemical Biology ·Mi Ra Chang,Liang Shi,Timothy S. Strutzenberg,Scott J. Novick,Yuanjun He,Rubén D. Garcia-Ordoñez,Rebecca L. Frkic,John B. Bruning,Theodore M. Kamenecka,Patrick R. Griffin	2019	8
18	Rational Design of a 3₁₀‐Helical PIP‐Box Mimetic Targeting PCNA, the Human Sliding Clamp Chemistry - A European Journal ·Kate L. Wegener,孫泰華,Nicholas E. Dixon,Aaron J. Oakley,Denis B. Scanlon,Andrew D. Abell,John B. Bruning	2018	17
19	Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor Insect Biochemistry and Molecular Biology ·Chao He,C. H. Lee,John B. Bruning,Amanda Choo,Simon W. Baxter	2016	43
20	Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method Proceedings of the National Academy of Sciences ·Susie Y. Dai,Michael J. Chalmers,John B. Bruning,Kelli Bramlett,Harold E. Osborne,Chahrzad Montrose‐Rafizadeh,Robert J. Barr,Yong Wang,Minmin Wang,Thomas P. Burris,Jeffrey A. Dodge,Patrick R. Griffin	2008	68

About John B. Bruning

John B. Bruning is a scholar working on Pharmacology, Biochemistry, Inorganic Chemistry, Molecular Biology and Oncology, having authored 123 papers that have together received 3.5k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (30 papers), Enzyme Structure and Function (22 papers), Metal-Catalyzed Oxygenation Mechanisms (18 papers), Peroxisome Proliferator-Activated Receptors (17 papers), Peptidase Inhibition and Analysis (15 papers), Metabolism, Diabetes, and Cancer (13 papers), Biochemical and Molecular Research (11 papers) and Estrogen and related hormone effects (10 papers). The work is most often cited by research in Pharmacology (414 citations), Molecular Biology (2.3k citations), Biochemistry (234 citations), Toxicology (72 citations) and Genetics (536 citations). John B. Bruning has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Patrick R. Griffin, Theodore M. Kamenecka, Michael J. Chalmers, Yousif Shamoo, K.W. Nettles, Scott A. Busby, Stephen G. Bell, Yuanjun He, James J. De Voss and Tom Coleman. Their work appears in journals such as ACS Catalysis, Journal of Biological Chemistry, Chemistry - A European Journal, Biochemistry and ACS Chemical Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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