Weiyi Toy

3.5k total citations · 1 hit paper
24 papers, 1.9k citations indexed

About

Weiyi Toy is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Weiyi Toy has authored 24 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 10 papers in Genetics and 7 papers in Oncology. Recurrent topics in Weiyi Toy's work include Estrogen and related hormone effects (9 papers), HER2/EGFR in Cancer Research (6 papers) and Computational Drug Discovery Methods (3 papers). Weiyi Toy is often cited by papers focused on Estrogen and related hormone effects (9 papers), HER2/EGFR in Cancer Research (6 papers) and Computational Drug Discovery Methods (3 papers). Weiyi Toy collaborates with scholars based in United States, Singapore and Australia. Weiyi Toy's co-authors include Sarat Chandarlapaty, Geoffrey L. Greene, Sean W. Fanning, José Baselga, Yang Shen, Zhiqiang Li, Marie Will, Michael F. Berger, Kinisha Gala and Clifford A. Hudis and has published in prestigious journals such as Journal of Clinical Investigation, Nature Genetics and Cancer Research.

In The Last Decade

Weiyi Toy

21 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

2013 855 citations Weiyi Toy, Yang Shen et al. Nature Genetics profile →

Peers

Weiyi Toy

ONCOL

GENET

PRM

Rinath Jeselsohn United States

Matthew H. Herynk United States

Jiang Shou United States

Luca Malorni Italy

S. G. Hilsenbeck United States

Erika Krasnickas Keeton United States

Teresa Klinowska United Kingdom

Ana Bosch Sweden

Rebecca E. Schweppe United States

Hisashi Hirakawa Japan

Rinath Jeselsohn United States

Weiyi Toy

953 ×0.9

1.1k ×1.4

ONCOL

583 ×0.9

GENET

743 ×1.2

814 ×1.3

PRM

Citations per year, relative to Weiyi Toy Weiyi Toy (= 1×) peers Rinath Jeselsohn

Countries citing papers authored by Weiyi Toy

Since Specialization

Citations

This map shows the geographic impact of Weiyi Toy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Weiyi Toy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Weiyi Toy more than expected).

Fields of papers citing papers by Weiyi Toy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Weiyi Toy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Weiyi Toy. The network helps show where Weiyi Toy may publish in the future.

Co-authorship network of co-authors of Weiyi Toy

This figure shows the co-authorship network connecting the top 25 collaborators of Weiyi Toy. A scholar is included among the top collaborators of Weiyi Toy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Weiyi Toy. Weiyi Toy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Zhou, Tingting, et al.. (2025). Overexpression of <i>DDR1</i> contributes to gastric cancer progression by inhibiting the Hippo pathway. Journal of Biomedical Research. 39(5). 500–500.

Richardson, Gary, Vladimir Andelkovic, Ganessan Kichenadasse, et al.. (2023). 88TiP A phase Ib study of HMBD-001, a monoclonal antibody targeting HER3, with or without chemotherapy in patients with genetic aberrations in HER3 signaling. Annals of Oncology. 34. S1501–S1501.

Irani, Seema, Qing Li, Weiyi Toy, et al.. (2023). Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation. Journal of Clinical Investigation. 134(1). 9 indexed citations

Kingston, Belinda, Alex Pearson, María Teresa Herrera-Abreu, et al.. (2023). ESR1 F404 Mutations and Acquired Resistance to Fulvestrant in ESR1 -Mutant Breast Cancer. Cancer Discovery. 14(2). 274–289. 21 indexed citations

Mayne, Christopher G., Weiyi Toy, Kathryn E. Carlson, et al.. (2021). Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular Cancer Research. 19(9). 1559–1570. 10 indexed citations

Toy, Weiyi, Pedram Razavi, Michael F. Berger, et al.. (2019). Abstract P5-04-11: Non-canonical, clinical ESR1 mutations promote resistance to antiestrogen therapies. Cancer Research. 79(4_Supplement). P5–4.

Ross, Dara S., Ahmet Zehir, Edi Brogi, et al.. (2018). Immunohistochemical analysis of estrogen receptor in breast cancer with ESR1 mutations detected by hybrid capture-based next-generation sequencing. Modern Pathology. 32(1). 81–87. 14 indexed citations

Toy, Weiyi, Hazel M. Weir, Pedram Razavi, et al.. (2016). Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists. Cancer Discovery. 7(3). 277–287. 269 indexed citations

Fanning, Sean W., Christopher G. Mayne, Venkatasubramanian Dharmarajan, et al.. (2016). Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. eLife. 5. 215 indexed citations

10.

Toy, Weiyi, Hazel M. Weir, Pedram Razavi, et al.. (2016). Abstract 863: Differential activity and SERD sensitivity of clinical ESR1 mutations. Cancer Research. 76(14_Supplement). 863–863. 1 indexed citations

11.

Fanning, Sean W., Christopher G. Mayne, Weiyi Toy, et al.. (2016). Abstract 4854: Bazedoxifene inhibits ESR1 somatic mutants with improved potency compared to tamoxifene and raloxifene. Cancer Research. 76(14_Supplement). 4854–4854. 2 indexed citations

12.

Will, Marie, Alice Can Ran Qin, Weiyi Toy, et al.. (2014). Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS–ERK Signaling. Cancer Discovery. 4(3). 334–347. 158 indexed citations

13.

Toy, Weiyi, Yang Shen, Helen Won, et al.. (2013). ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nature Genetics. 45(12). 1439–1445. 855 indexed citations breakdown →

14.

Toy, Weiyi, et al.. (2013). Elevated Undercarboxylated and Reduced Carboxylated Osteocalcin are Associated with Metabolic Syndrome in Middle Age Asian Females. Experimental and Clinical Endocrinology & Diabetes. 121(6). 329–333. 12 indexed citations

15.

Yang, Yixuan, Weiyi Toy, Peiling Hou, et al.. (2012). Discovery of SLC3A2 Cell Membrane Protein as a Potential Gastric Cancer Biomarker: Implications in Molecular Imaging. Journal of Proteome Research. 11(12). 5736–5747. 51 indexed citations

16.

Lim, Su Lin, et al.. (2011). Elevated NRD1 metalloprotease expression plays a role in breast cancer growth and proliferation. Genes Chromosomes and Cancer. 50(10). 837–847. 7 indexed citations

17.

Lim, Shen Kiat, et al.. (2011). Tyrosine phosphorylation of transcriptional coactivator WW‐domain binding protein 2 regulates estrogen receptor α function in breast cancer via the Wnt pathway. The FASEB Journal. 25(9). 3004–3018. 47 indexed citations

18.

Toy, Weiyi, et al.. (2009). EGF-induced tyrosine phosphorylation of Endofin is dependent on PI3K activity and proper localization to endosomes. Cellular Signalling. 22(3). 437–446. 7 indexed citations

19.

Toy, Weiyi, et al.. (2008). Novel Breast Cancer Metastasis-Associated Proteins. Journal of Proteome Research. 8(2). 583–594. 105 indexed citations

20.

Chen, Yunhao, Teck Yew Low, Rajarshi Ray, et al.. (2007). Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells. PROTEOMICS. 7(14). 2384–2397. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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