P. Filippakopoulos

18.1k citations

87 papers · 9.8k indexed · 3 hit papers · h-index 53

Molecular Biology top 0.5%
Hematology top 0.2%
Oncology top 2%
Organic Chemistry top 2%
Immunology top 5%

Co-authors: Stefan Knapp Susanne Müller S. Picaud Takao Fujisawa O. Fedorov I. Felletar Anne‐Claude Gingras Tracy Keates
Topics: Protein Degradation and Inhibitors (47 papers)Multiple Myeloma Research and Treatments (22 papers)Histone Deacetylase Inhibitors Research (19 papers)
Cited by: Hematology Molecular Biology Oncology
Journals: Cell Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United Kingdom United States Germany

In The Last Decade

P. Filippakopoulos

85 papers receiving 9.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

2012 1.2k citations P. Filippakopoulos, S. Picaud et al. Cell profile →
Targeting bromodomains: epigenetic readers of lysine acetylation

2014 957 citations P. Filippakopoulos, Stefan Knapp profile →
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

2017 419 citations P. Filippakopoulos et al. profile →

Peers

Countries citing papers authored by P. Filippakopoulos

Since Specialization

Citations

This map shows the geographic impact of P. Filippakopoulos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by P. Filippakopoulos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites P. Filippakopoulos more than expected).

Fields of papers citing papers by P. Filippakopoulos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by P. Filippakopoulos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by P. Filippakopoulos. The network helps show where P. Filippakopoulos may publish in the future.

Co-authorship network of co-authors of P. Filippakopoulos

This figure shows the co-authorship network connecting the top 25 collaborators of P. Filippakopoulos. A scholar is included among the top collaborators of P. Filippakopoulos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with P. Filippakopoulos. P. Filippakopoulos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Water Networks as Hydrophobic Recognition Motifs in Proteins 2025 ·Angewandte Chemie International Edition ·(unknown),(unknown),Salvatore Scaffidi,(unknown),(unknown),(unknown),S. Picaud,T. Krojer,P. Filippakopoulos,F. von Delft,Carmen Escolano,Carles Galdeano,Xavier Barril	1
2	Acetylation reprograms MITF target selectivity and residence time 2023 ·Nature Communications ·Pakavarin Louphrasitthiphol,Alessia Loffreda,Vivian Pogenberg,S. Picaud,Alexander Schepsky,Hans Friedrichsen,Zhiqiang Zeng,Anahita Lashgari,Benjamin Thomas,E. Elizabeth Patton,Matthias Wilmanns,P. Filippakopoulos,Jean‐Philippe Lambert,Eirı́kur Steingrı́msson,Davide Mazza,Colin R. Goding	10
3	Discovery of Benzo[d]imidazole‐6‐sulfonamides as Bromodomain and Extra‐Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain 2022 ·ChemMedChem ·Alessandra Cipriano,Ciro Milite,Alessandra Feoli,Monica Viviano,Giacomo Pepe,Pietro Campiglia,(unknown),S. Picaud,Satomi Imaide,Nikolai Makukhin,P. Filippakopoulos,Alessio Ciulli,Sabrina Castellano,Gianluca Sbardella	9
4	Probing BRD Inhibition Substituent Effects in Bulky Analogues of (+)‐JQ1 2021 ·Helvetica Chimica Acta ·(unknown),S. Picaud,(unknown),(unknown),Régis Millet,Gilles Gasser,Roger Alberto,Hannah J. Maple,Robert Felix,Zbigniew J. Leśnikowski,Helen Stewart,Timothy Chevassut,Simon Morley,P. Filippakopoulos,John Spencer	1
5	The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif 2021 ·PLoS ONE ·Petra Lukacik,David Owen,Gemma Harris,Jani Reddy Bolla,S. Picaud,(unknown),Joanne E. Nettleship,Louise E. Bird,Raymond J. Owens,Philip C. Biggin,P. Filippakopoulos,Carol V. Robinson,Martin Walsh	7
6	Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function 2021 ·Frontiers in Immunology ·Adam P. Cribbs,P. Filippakopoulos,Martin Philpott,Graham Wells,Henry Penn,Henrik Oerum,Viia Valge-Archer,Marc Feldmann,Udo Oppermann	19
7	BET inhibition disrupts transcription but retains enhancer-promoter contact 2021 ·Nature Communications ·Nicholas T. Crump,Erica Ballabio,Laura Godfrey,Ross Thorne,Emmanouela Repapi,Jon Kerry,Marta Tapia,Hua Peng,B. Christoffer Lagerholm,P. Filippakopoulos,James Davies,Thomas A. Milne	76
8	Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma 2019 ·Leukemia ·Yan Song,Paul M.C. Park,Lei Wu,Arghya Ray,S. Picaud,Deyao Li,(unknown),Ting Du,P. Filippakopoulos,Kenneth C. Anderson,Jun Qi,Dharminder Chauhan	31
9	The C-terminal extension landscape of naturally presented HLA-I ligands 2018 ·Proceedings of the National Academy of Sciences ·Philippe Guillaume,S. Picaud,Petra Baumgaertner,Nicole Montandon,Julien Schmidt,Daniel E. Speiser,George Coukos,Michal Bassani‐Sternberg,P. Filippakopoulos,David Gfeller	35
10	A TFEB nuclear export signal integrates amino acid supply and glucose availability 2018 ·Nature Communications ·(unknown),Hans Friedrichsen,(unknown),S. Picaud,Laurent Volpon,Kao Chin Ngeow,(unknown),Román Fischer,Katherine L.B. Borden,P. Filippakopoulos,Colin R. Goding	95
11	Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors 2017 ·Oncogenesis ·Kate E Lines,Mark Stevenson,P. Filippakopoulos,Susanne Müller,Helen Lockstone,Benjamin Wright,Simona Grozinsky‐Glasberg,Ashley Grossman,Stefan Knapp,David Buck,C. Bountra,Rajesh V. Thakker	39
12	Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells 2016 ·Molecular Cancer Therapeutics ·Lars Tögel,(unknown),Anderly C. Chüeh,Aparna Jayachandran,Hoanh Tran,Toby J. Phesse,Rui Wu,Oliver M. Sieber,Diego Arango,Amardeep S. Dhillon,Mark A. Dawson,Beatriz Díez-Dacal,Timothy C. Gahman,P. Filippakopoulos,Andrew K. Shiau,John M. Mariadason	74
13	A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction 2014 ·Angewandte Chemie ·Timothy P. C. Rooney,P. Filippakopoulos,O. Fedorov,S. Picaud,(unknown),Duncan A. Hay,Sarah Martin,Anthony Tumber,Catherine Rogers,Martin Philpott,Minghua Wang,Amber L. Thompson,Tom D. Heightman,David C. Pryde,Andrew S. Cook,Robert S. Paton,Susanne Müller,Stefan Knapp,Paul E. Brennan,Stuart J. Conway	13
14	A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction 2014 ·Angewandte Chemie International Edition ·Timothy P. C. Rooney,P. Filippakopoulos,O. Fedorov,S. Picaud,Wilian A. Cortopassi,Duncan A. Hay,Sarah Martin,Anthony Tumber,Catherine Rogers,Martin Philpott,Minghua Wang,Amber L. Thompson,Tom D. Heightman,David C. Pryde,Andrew S. Cook,Robert S. Paton,Susanne Müller,Stefan Knapp,Paul E. Brennan,Stuart J. Conway	93
15	Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Familybreakdown → 2012 ·Cell ·P. Filippakopoulos,S. Picaud,Maria Mangos,Tracy Keates,Jean‐Philippe Lambert,Dalia Baršytė-Lovejoy,I. Felletar,Rudolf Volkmer,Susanne Müller,Tony Pawson,Anne‐Claude Gingras,C.H. Arrowsmith,Stefan Knapp	1230
16	Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery 2011 ·Molecular BioSystems ·Martin Philpott,Jing Yang,(unknown),O. Fedorov,Sagar Uttarkar,P. Filippakopoulos,S. Picaud,Tracy Keates,I. Felletar,Alessio Ciulli,Stefan Knapp,Tom D. Heightman	107
17	Bromodomains as therapeutic targets 2011 ·Expert Reviews in Molecular Medicine ·Susanne Müller,P. Filippakopoulos,Stefan Knapp	343
18	Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family 2011 ·Bioorganic & Medicinal Chemistry ·P. Filippakopoulos,S. Picaud,O. Fedorov,Marco Keller,(unknown),Olaf Morgenstern,Franz Bracher,Stefan Knapp	97
19	Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function 2010 ·Nature Chemical Biology ·Nicholas Kwiatkowski,Nannette Jelluma,P. Filippakopoulos,M. Soundararajan,Michael S. Manak,Mijung Kwon,Hwan Geun Choi,Taebo Sim,Quinn L. Deveraux,Sabine Rottmann,David Pellman,Jagesh V. Shah,Geert J.P.L. Kops,Stefan Knapp,Nathanael S. Gray	177
20	Structural Analysis Identifies Imidazo[1,2- b ]Pyridazines as PIM Kinase Inhibitors with In vitro Antileukemic Activity 2007 ·Cancer Research ·Vanda Pogačić,Alex N. Bullock,O. Fedorov,P. Filippakopoulos,Christelle Gasser,Andrea Biondi,Sandrine Meyer‐Monard,Stefan Knapp,Juerg Schwaller	169

About P. Filippakopoulos

P. Filippakopoulos is a scholar working on Hematology, Molecular Biology and Oncology, having authored 87 papers that have together received 9.8k indexed citations. Recurring topics across this work include Protein Degradation and Inhibitors (47 papers), Multiple Myeloma Research and Treatments (22 papers) and Histone Deacetylase Inhibitors Research (19 papers). The work is most often cited by research in Hematology (2.4k citations), Molecular Biology (8.3k citations) and Oncology (1.6k citations). P. Filippakopoulos has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Stefan Knapp, Susanne Müller, S. Picaud, Takao Fujisawa, O. Fedorov, I. Felletar, Anne‐Claude Gingras, Tracy Keates, Tony Pawson and Jean‐Philippe Lambert. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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