P. Filippakopoulos

18.1k citations

87 papers · 9.8k indexed · 3 hit papers · h-index 53

Hematology top 0.2%
- Multiple Myeloma Research and Treatments 22
Molecular Biology top 0.5%
- Protein Degradation and Inhibitors 47
- Histone Deacetylase Inhibitors Research 19
- Ubiquitin and proteasome pathways 16
- Genomics and Chromatin Dynamics 8
- Protein Kinase Regulation and GTPase Signaling 7
Oncology top 2%
- Peptidase Inhibition and Analysis 10
Virology top 2%
Cell Biology top 2%
Pathology and Forensic Medicine
- Cancer Mechanisms and Therapy 7

Co-authors: Stefan Knapp Susanne Müller S. Picaud Takao Fujisawa O. Fedorov I. Felletar Anne‐Claude Gingras Tracy Keates
Cited by: Hematology Molecular Biology Oncology
Journals: Cell (4 papers)Proceedings of the National Academy of Sciences (4 papers)Journal of the American Chemical Society (2 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

P. Filippakopoulos

85 papers receiving 9.6k citations

Hit Papers

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Peers

Countries citing papers authored by P. Filippakopoulos

Since Specialization

Citations

This map shows the geographic impact of P. Filippakopoulos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by P. Filippakopoulos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites P. Filippakopoulos more than expected).

Fields of papers citing papers by P. Filippakopoulos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by P. Filippakopoulos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by P. Filippakopoulos. The network helps show where P. Filippakopoulos may publish in the future.

Co-authorship network

The 25 scholars most cited alongside P. Filippakopoulos, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with P. Filippakopoulos Line = papers co-authored together P. Filippakopoulos links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Water Networks as Hydrophobic Recognition Motifs in Proteins Angewandte Chemie International Edition ·Serena G. Piticchio,Miriam Martínez‐Cartró,Salvatore Scaffidi,Sergio Rodríguez‐Arévalo,Andrea Bagán,Ainoa Sánchez‐Arfelis,S. Picaud,T. Krojer,P. Filippakopoulos,F. von Delft,Carmen Escolano,Carles Galdeano,Xavier Barril	2025	1
2	Acetylation reprograms MITF target selectivity and residence time Nature Communications ·Pakavarin Louphrasitthiphol,Alessia Loffreda,Vivian Pogenberg,S. Picaud,Alexander Schepsky,Hans Friedrichsen,Zhiqiang Zeng,Anahita Lashgari,Benjamin Thomas,E. Elizabeth Patton,Matthias Wilmanns,P. Filippakopoulos,Jean‐Philippe Lambert,Eirı́kur Steingrı́msson,Davide Mazza,Colin R. Goding	2023	10
3	Discovery of Benzo[d]imidazole‐6‐sulfonamides as Bromodomain and Extra‐Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain ChemMedChem ·Alessandra Cipriano,Ciro Milite,Alessandra Feoli,Monica Viviano,Giacomo Pepe,Pietro Campiglia,Giuliana Sarno,S. Picaud,Satomi Imaide,Nikolai Makukhin,P. Filippakopoulos,Alessio Ciulli,Sabrina Castellano,Gianluca Sbardella	2022	9
4	Probing BRD Inhibition Substituent Effects in Bulky Analogues of (+)‐JQ1 Helvetica Chimica Acta ·Storm Hassell‐Hart,S. Picaud,Raphael Lengacher,Joshua Csucker,Régis Millet,Gilles Gasser,Roger Alberto,Hannah J. Maple,Robert Felix,Zbigniew J. Leśnikowski,Helen Stewart,Timothy Chevassut,Simon Morley,P. Filippakopoulos,John Spencer	2021	1
5	The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif PLoS ONE ·Petra Lukacik,David Owen,Gemma Harris,Jani Reddy Bolla,S. Picaud,Irfan Alibay,Joanne E. Nettleship,Louise E. Bird,Raymond J. Owens,Philip C. Biggin,P. Filippakopoulos,Carol V. Robinson,Martin Walsh	2021	7
6	Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function Frontiers in Immunology ·Adam P. Cribbs,P. Filippakopoulos,Martin Philpott,Graham Wells,Henry Penn,Henrik Oerum,Viia Valge-Archer,Marc Feldmann,Udo Oppermann	2021	19
7	BET inhibition disrupts transcription but retains enhancer-promoter contact Nature Communications ·Nicholas T. Crump,Erica Ballabio,Laura Godfrey,Ross Thorne,Emmanouela Repapi,Jon Kerry,Marta Tapia,Hua Peng,B. Christoffer Lagerholm,P. Filippakopoulos,James Davies,Thomas A. Milne	2021	76
8	Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma Leukemia ·Yan Song,Paul M.C. Park,Lei Wu,Arghya Ray,S. Picaud,Deyao Li,Virangika K. Wimalasena,Ting Du,P. Filippakopoulos,Kenneth C. Anderson,Jun Qi,Dharminder Chauhan	2019	31
9	The C-terminal extension landscape of naturally presented HLA-I ligands Proceedings of the National Academy of Sciences ·Philippe Guillaume,S. Picaud,Petra Baumgaertner,Nicole Montandon,Julien Schmidt,Daniel E. Speiser,George Coukos,Michal Bassani‐Sternberg,P. Filippakopoulos,David Gfeller	2018	35
10	A TFEB nuclear export signal integrates amino acid supply and glucose availability Nature Communications ·Linxin Li,Hans Friedrichsen,S. D. Andrews,S. Picaud,Laurent Volpon,Kao Chin Ngeow,Georgina Berridge,Román Fischer,Katherine L.B. Borden,P. Filippakopoulos,Colin R. Goding	2018	95
11	Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors Oncogenesis ·Kate E Lines,Mark Stevenson,P. Filippakopoulos,Susanne Müller,Helen Lockstone,Benjamin Wright,Simona Grozinsky‐Glasberg,Ashley Grossman,Stefan Knapp,David Buck,C. Bountra,Rajesh V. Thakker	2017	39
12	Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells Molecular Cancer Therapeutics ·Lars Tögel,Rebecca Nightingale,Anderly C. Chüeh,Aparna Jayachandran,Hoanh Tran,Toby J. Phesse,Rui Wu,Oliver M. Sieber,Diego Arango,Amardeep S. Dhillon,Mark A. Dawson,Beatriz Díez-Dacal,Timothy C. Gahman,P. Filippakopoulos,Andrew K. Shiau,John M. Mariadason	2016	74
13	A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction Angewandte Chemie ·Timothy P. C. Rooney,P. Filippakopoulos,O. Fedorov,S. Picaud,Wilian A. Cortopassi,Duncan A. Hay,Sarah Martin,Anthony Tumber,Catherine Rogers,Martin Philpott,Minghua Wang,Amber L. Thompson,Tom D. Heightman,David C. Pryde,Andrew S. Cook,Robert S. Paton,Susanne Müller,Stefan Knapp,Paul E. Brennan,Stuart J. Conway	2014	13
14	A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction Angewandte Chemie International Edition ·Timothy P. C. Rooney,P. Filippakopoulos,O. Fedorov,S. Picaud,Wilian A. Cortopassi,Duncan A. Hay,Sarah Martin,Anthony Tumber,Catherine Rogers,Martin Philpott,Minghua Wang,Amber L. Thompson,Tom D. Heightman,David C. Pryde,Andrew S. Cook,Robert S. Paton,Susanne Müller,Stefan Knapp,Paul E. Brennan,Stuart J. Conway	2014	93
15	Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Familybreakdown → Cell ·P. Filippakopoulos,S. Picaud,Maria Mangos,Tracy Keates,Jean‐Philippe Lambert,Dalia Baršytė-Lovejoy,I. Felletar,Rudolf Volkmer,Susanne Müller,Tony Pawson,Anne‐Claude Gingras,C.H. Arrowsmith,Stefan Knapp	2012	1230
16	Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery Molecular BioSystems ·Martin Philpott,Jing Yang,Tony Tumber,O. Fedorov,Sagar Uttarkar,P. Filippakopoulos,S. Picaud,Tracy Keates,I. Felletar,Alessio Ciulli,Stefan Knapp,Tom D. Heightman	2011	107
17	Bromodomains as therapeutic targets Expert Reviews in Molecular Medicine ·Susanne Müller,P. Filippakopoulos,Stefan Knapp	2011	343
18	Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family Bioorganic & Medicinal Chemistry ·P. Filippakopoulos,S. Picaud,O. Fedorov,Marco Keller,Matthias Wrobel,Olaf Morgenstern,Franz Bracher,Stefan Knapp	2011	97
19	Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function Nature Chemical Biology ·Nicholas Kwiatkowski,Nannette Jelluma,P. Filippakopoulos,M. Soundararajan,Michael S. Manak,Mijung Kwon,Hwan Geun Choi,Taebo Sim,Quinn L. Deveraux,Sabine Rottmann,David Pellman,Jagesh V. Shah,Geert J.P.L. Kops,Stefan Knapp,Nathanael S. Gray	2010	177
20	Structural Analysis Identifies Imidazo[1,2- b ]Pyridazines as PIM Kinase Inhibitors with In vitro Antileukemic Activity Cancer Research ·Vanda Pogačić,Alex N. Bullock,O. Fedorov,P. Filippakopoulos,Christelle Gasser,Andrea Biondi,Sandrine Meyer‐Monard,Stefan Knapp,Juerg Schwaller	2007	169

About P. Filippakopoulos

P. Filippakopoulos is a scholar working on Hematology, Molecular Biology and Oncology, having authored 87 papers that have together received 9.8k indexed citations. Recurring topics across this work include Protein Degradation and Inhibitors (47 papers), Multiple Myeloma Research and Treatments (22 papers), Histone Deacetylase Inhibitors Research (19 papers), Ubiquitin and proteasome pathways (16 papers), Peptidase Inhibition and Analysis (10 papers), Genomics and Chromatin Dynamics (8 papers), Protein Kinase Regulation and GTPase Signaling (7 papers) and Cancer Mechanisms and Therapy (7 papers). The work is most often cited by research in Hematology (2.4k citations), Molecular Biology (8.3k citations) and Oncology (1.6k citations). P. Filippakopoulos has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Stefan Knapp, Susanne Müller, S. Picaud, Takao Fujisawa, O. Fedorov, I. Felletar, Anne‐Claude Gingras, Tracy Keates, Tony Pawson and Jean‐Philippe Lambert. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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