Dean C. Singleton

2.2k total citations · 1 hit paper
24 papers, 1.6k citations indexed

About

Dean C. Singleton is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Dean C. Singleton has authored 24 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 10 papers in Cancer Research and 8 papers in Oncology. Recurrent topics in Dean C. Singleton's work include Cancer, Hypoxia, and Metabolism (8 papers), Cancer Research and Treatments (5 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Dean C. Singleton is often cited by papers focused on Cancer, Hypoxia, and Metabolism (8 papers), Cancer Research and Treatments (5 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Dean C. Singleton collaborates with scholars based in New Zealand, United States and United Kingdom. Dean C. Singleton's co-authors include Adrian L. Harris, William R. Wilson, Andrew Macann, Tomasz Rzymski, Manuela Milani, Catherine Rogers, Stefan Knapp, Susanne Müller, C. Tallant and Octovia Monteiro and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and SHILAP Revista de lepidopterología.

In The Last Decade

Dean C. Singleton

22 papers receiving 1.6k citations

Hit Papers

Therapeutic targeting of the hypoxic tumour microenvironment 2021 2026 2022 2024 2021 100 200 300
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Therapeutic targeting of the hypoxic tumour microenvironment
    2021 338 citations Dean C. Singleton, Andrew Macann et al. Nature Reviews Clinical Oncology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Dean C. Singleton New Zealand 14 1.0k 367 272 243 215 24 1.6k
Metin Kurtoğlu United States 20 1.2k 1.1× 796 2.2× 423 1.6× 243 1.0× 180 0.8× 38 2.0k
Kristina Viktorsson Sweden 27 1.5k 1.5× 469 1.3× 637 2.3× 146 0.6× 159 0.7× 70 2.2k
Malin Wickström Sweden 27 1.3k 1.3× 420 1.1× 650 2.4× 158 0.7× 116 0.5× 63 2.2k
Melissa Millard United States 14 1.1k 1.1× 228 0.6× 298 1.1× 145 0.6× 151 0.7× 18 1.9k
Fernando Doñate United States 22 897 0.9× 341 0.9× 508 1.9× 69 0.3× 83 0.4× 56 1.8k
Rima Al‐awar Canada 29 1.3k 1.3× 261 0.7× 498 1.8× 75 0.3× 63 0.3× 65 2.2k
J I Johnson United States 7 1.3k 1.2× 316 0.9× 853 3.1× 118 0.5× 102 0.5× 7 2.0k
Evan R. Lewis United States 13 1.3k 1.3× 701 1.9× 467 1.7× 115 0.5× 48 0.2× 20 2.0k
Dong Soon Choi United States 15 566 0.5× 214 0.6× 445 1.6× 127 0.5× 246 1.1× 29 1.3k
Carolyn Sidor United States 20 871 0.8× 433 1.2× 553 2.0× 111 0.5× 45 0.2× 42 1.6k

Countries citing papers authored by Dean C. Singleton

Since Specialization
Citations

This map shows the geographic impact of Dean C. Singleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dean C. Singleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dean C. Singleton more than expected).

Fields of papers citing papers by Dean C. Singleton

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dean C. Singleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dean C. Singleton. The network helps show where Dean C. Singleton may publish in the future.

Co-authorship network of co-authors of Dean C. Singleton

This figure shows the co-authorship network connecting the top 25 collaborators of Dean C. Singleton. A scholar is included among the top collaborators of Dean C. Singleton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dean C. Singleton. Dean C. Singleton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Kalev‐Zylinska, Maggie L., et al.. (2024). Megakaryocyte maturation involves activation of the adaptive unfolded protein response. Genes to Cells. 29(10). 889–901. 1 indexed citations
3.
Lee, Tet Woo, Dean C. Singleton, Moana Tercel, et al.. (2024). Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models. Molecular Oncology. 18(8). 1885–1903. 1 indexed citations
4.
5.
Singleton, Dean C., Andrew Macann, & William R. Wilson. (2021). Therapeutic targeting of the hypoxic tumour microenvironment. Nature Reviews Clinical Oncology. 18(12). 751–772. 338 indexed citations breakdown →
6.
Singleton, Dean C., Alexandra M. Mowday, Christopher P. Guise, et al.. (2021). Bioreductive prodrug PR-104 improves the tumour distribution and titre of the nitroreductase-armed oncolytic adenovirus ONYX-411NTR leading to therapeutic benefit. Cancer Gene Therapy. 29(7). 1021–1032. 6 indexed citations
7.
8.
Singleton, Dean C., et al.. (2020). Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer. BMC Cancer. 20(1). 470–470. 29 indexed citations
9.
Green, Taryn N., Martin Chopra, Nicholas Knowlton, et al.. (2020). N-Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation. Thrombosis and Haemostasis. 120(4). 671–686. 11 indexed citations
10.
Singleton, Dean C., et al.. (2019). Hypoxia‐Activated Prodrugs of PERK Inhibitors. Chemistry - An Asian Journal. 14(8). 1238–1248. 11 indexed citations
11.
Leung, Euphemia, Marjan Askarian-Amiri, Dean C. Singleton, et al.. (2018). Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations. Frontiers in Oncology. 8. 425–425. 13 indexed citations
12.
McIntyre, Alan, Alžbeta Hulı́ková, Ioanna Ledaki, et al.. (2016). Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth. Cancer Research. 76(13). 3744–3755. 77 indexed citations
13.
Clark, Peter G. K., Lucas Campos Curcino Vieira, C. Tallant, et al.. (2015). LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Angewandte Chemie. 127(21). 6315–6319. 111 indexed citations
14.
Clark, Peter G. K., Lucas Campos Curcino Vieira, C. Tallant, et al.. (2015). LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Angewandte Chemie International Edition. 54(21). 6217–6221. 134 indexed citations
15.
Singleton, Dean C., Pegah Rouhi, Christos E. Zois, et al.. (2014). Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. Oncogene. 34(36). 4713–4722. 36 indexed citations
16.
Kumar, Krishan, Simon Wigfield, Harriet E. Gee, et al.. (2013). Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine. 91(6). 749–758. 63 indexed citations
17.
Singleton, Dean C. & Adrian L. Harris. (2012). Targeting the ATF4 pathway in cancer therapy. Expert Opinion on Therapeutic Targets. 16(12). 1189–1202. 109 indexed citations
18.
Rzymski, Tomasz, Manuela Milani, Dean C. Singleton, & Adrian L. Harris. (2009). Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia. Cell Cycle. 8(23). 3838–3847. 163 indexed citations
19.
Dachs, Gabi U., et al.. (2009). Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy. Molecules. 14(11). 4517–4545. 91 indexed citations
20.
Singleton, Dean C., Sophie P. Syddall, Jeff B. Smaill, et al.. (2007). The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411NTR. Cancer Gene Therapy. 14(12). 953–967. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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