Alessio Ciulli

13.9k total citations · 5 hit papers
133 papers, 8.8k citations indexed

About

Alessio Ciulli is a scholar working on Molecular Biology, Oncology and Hematology. According to data from OpenAlex, Alessio Ciulli has authored 133 papers receiving a total of 8.8k indexed citations (citations by other indexed papers that have themselves been cited), including 128 papers in Molecular Biology, 42 papers in Oncology and 28 papers in Hematology. Recurrent topics in Alessio Ciulli's work include Protein Degradation and Inhibitors (92 papers), Ubiquitin and proteasome pathways (80 papers) and Peptidase Inhibition and Analysis (36 papers). Alessio Ciulli is often cited by papers focused on Protein Degradation and Inhibitors (92 papers), Ubiquitin and proteasome pathways (80 papers) and Peptidase Inhibition and Analysis (36 papers). Alessio Ciulli collaborates with scholars based in United Kingdom, United States and Italy. Alessio Ciulli's co-authors include Kwok-Ho Chan, Michael Zengerle, Andrea Testa, Scott J. Hughes, Morgan S. Gadd, Xavier Lucas, Chris Abell, Inge Van Molle, Chiara Maniaci and Teresa A.F. Cardote and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Alessio Ciulli

131 papers receiving 8.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis of PROTAC cooperative recognition for selective protein degradation

2017 826 citations Morgan S. Gadd, Andrea Testa et al. profile →
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

2015 760 citations Kwok-Ho Chan, Alessio Ciulli et al. profile →
E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones

2020 233 citations Tasuku Ishida, Alessio Ciulli SLAS DISCOVERY profile →
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

2021 168 citations Satomi Imaide, Nikolai Makukhin et al. profile →
Targeted protein degradation for cancer therapy

2025 27 citations Alessio Ciulli et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alessio Ciulli United Kingdom	49	8.2k	2.9k	1.8k	658	463	133	8.8k
P. Filippakopoulos United Kingdom	53	8.3k 1.0×	1.6k 0.5×	2.4k 1.3×	960 1.5×	434 0.9×	87	9.8k
O. Fedorov United Kingdom	41	4.4k 0.5×	832 0.3×	1.2k 0.6×	731 1.1×	462 1.0×	56	5.4k
Chao‐Yie Yang United States	42	5.7k 0.7×	1.9k 0.7×	789 0.4×	1.0k 1.5×	1.1k 2.5×	105	7.1k
Pascal Furet Switzerland	50	5.6k 0.7×	2.4k 0.8×	1.1k 0.6×	2.0k 3.0×	592 1.3×	125	8.6k
Chun‐wa Chung United Kingdom	32	3.4k 0.4×	735 0.3×	997 0.5×	538 0.8×	303 0.7×	76	4.3k
Lyubomir T. Vassilev United States	36	7.0k 0.9×	5.0k 1.8×	492 0.3×	887 1.3×	267 0.6×	70	9.3k
Saul H. Rosenberg United States	44	5.6k 0.7×	2.3k 0.8×	465 0.3×	1.7k 2.6×	543 1.2×	118	8.2k
Adrian M. Senderowicz United States	45	4.9k 0.6×	3.8k 1.3×	452 0.2×	602 0.9×	159 0.3×	110	8.1k
Shiro Akinaga Japan	43	3.7k 0.5×	1.8k 0.6×	459 0.2×	470 0.7×	267 0.6×	122	6.6k
Bradford Graves United States	26	5.2k 0.6×	3.6k 1.3×	289 0.2×	1.1k 1.7×	281 0.6×	45	7.3k

Countries citing papers authored by Alessio Ciulli

Since Specialization

Citations

This map shows the geographic impact of Alessio Ciulli's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessio Ciulli with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessio Ciulli more than expected).

Fields of papers citing papers by Alessio Ciulli

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessio Ciulli. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessio Ciulli. The network helps show where Alessio Ciulli may publish in the future.

Co-authorship network of co-authors of Alessio Ciulli

This figure shows the co-authorship network connecting the top 25 collaborators of Alessio Ciulli. A scholar is included among the top collaborators of Alessio Ciulli based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alessio Ciulli. Alessio Ciulli is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Payne, N. Connor, David Zollman, Mei Chen, et al.. (2025). A method for the detection and enrichment of endogenous cereblon substrates. Cell chemical biology. 32(8). 1028–1041.e13. 1 indexed citations

Wolf, Gernot, Conner Craigon, Shao Thing Teoh, et al.. (2025). The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells. Cell chemical biology. 32(2). 291–306.e6. 9 indexed citations

Ma, Ning, S. Bhattacharya, Zuzana Jandová, et al.. (2025). Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes. Nature Communications. 16(1). 8595–8595. 2 indexed citations

Đikić, Ivan, et al.. (2025). Opportunities in proximity modulation: Bridging academia and industry. Molecular Cell. 85(16). 3012–3022.

Ridewood, Sophie, Robert J. Smith, Riccardo Zenezini Chiozzi, et al.. (2025). Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV. Nature Communications. 16(1). 1484–1484. 9 indexed citations

Nakasone, Mark A., Conner Craigon, Gajanan Sathe, et al.. (2024). Mechanism of degrader-targeted protein ubiquitinability. Science Advances. 10(41). eado6492–eado6492. 25 indexed citations

Furihata, Hirotake, Sohini Chakraborti, Kevin Haubrich, et al.. (2024). Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders. Nature Communications. 15(1). 8885–8885. 10 indexed citations

Vu, Lan Phuong, Claudia J. Diehl, Ryan Casement, et al.. (2023). Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel–Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers. Journal of Medicinal Chemistry. 66(18). 12776–12811. 11 indexed citations

Ciulli, Alessio, Chun‐wa Chung, Ingo V. Hartung, et al.. (2023). The 17^th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders. ChemMedChem. 18(20). e202300464–e202300464. 7 indexed citations

10.

Cipriano, Alessandra, Ciro Milite, Alessandra Feoli, et al.. (2022). Discovery of Benzo[d]imidazole‐6‐sulfonamides as Bromodomain and Extra‐Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain. ChemMedChem. 17(20). e202200343–e202200343. 9 indexed citations

11.

Ciulli, Alessio, et al.. (2021). Estimating the cooperativity of PROTAC-induced ternary complexes using ¹⁹ F NMR displacement assay. RSC Medicinal Chemistry. 12(10). 1765–1770. 13 indexed citations

12.

Bond, Adam G., Conner Craigon, Kwok-Ho Chan, et al.. (2021). Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins. Journal of Medicinal Chemistry. 64(20). 15477–15502. 63 indexed citations

13.

Ishida, Tasuku & Alessio Ciulli. (2020). E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones. SLAS DISCOVERY. 26(4). 484–502. 233 indexed citations breakdown →

14.

Testa, Andrea, Scott J. Hughes, Xavier Lucas, Jane E. Wright, & Alessio Ciulli. (2019). Structure‐Based Design of a Macrocyclic PROTAC. Angewandte Chemie International Edition. 59(4). 1727–1734. 172 indexed citations

15.

Testa, Andrea, Scott J. Hughes, Xavier Lucas, Jane E. Wright, & Alessio Ciulli. (2019). Structure‐Based Design of a Macrocyclic PROTAC. Angewandte Chemie. 132(4). 1744–1751. 19 indexed citations

16.

Cardote, Teresa A.F., Morgan S. Gadd, & Alessio Ciulli. (2017). Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex. Structure. 25(6). 901–911.e3. 110 indexed citations

17.

Bulatov, Emil & Alessio Ciulli. (2015). Targeting Cullin–RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation. Biochemical Journal. 467(3). 365–386. 185 indexed citations

18.

Silvestre, H.L., T.L. Blundell, Chris Abell, & Alessio Ciulli. (2013). Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proceedings of the National Academy of Sciences. 110(32). 12984–12989. 81 indexed citations

19.

Buckley, Dennis L., Inge Van Molle, Peter C. Gareiss, et al.. (2012). Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction. Journal of the American Chemical Society. 134(10). 4465–4468. 402 indexed citations

20.

Philpott, Martin, Jing Yang, O. Fedorov, et al.. (2011). Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery. Molecular BioSystems. 7(10). 2899–2908. 107 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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