Noriko Uchiyama

1.3k citations

28 papers · 769 indexed · h-index 14

Molecular Biology
- Wnt/β-catenin signaling in development and cancer 4
- Melanoma and MAPK Pathways 2
Organic Chemistry top 10%
- Synthesis and biological activity 2
- Synthesis and Reactivity of Heterocycles 2
Computational Theory and Mathematics top 5%
Pharmacology top 10%
Oncology
- Cancer-related Molecular Pathways 3
Cell Biology
- Microtubule and mitosis dynamics 3
Genetics
- Chronic Lymphocytic Leukemia Research 2
- Genetic and rare skin diseases. 2

Co-authors: Tomohiro Kawamoto Morihisa Saitoh Eiji Kimura Jun Kunitomo Hiroki Iwashita Masakuni Kori Yumiko Uno Douglas R. Dougan
Cited by: Molecular Biology Organic Chemistry Computational Theory and Mathematics
Journals: The Journal of Experimental Medicine (1 paper)Brain Research (1 paper)Biochemical and Biophysical Research Communications (1 paper)
Partner nations: Japan United States Canada

In The Last Decade

Noriko Uchiyama

27 papers receiving 754 citations

Peers

Countries citing papers authored by Noriko Uchiyama

Since Specialization

Citations

This map shows the geographic impact of Noriko Uchiyama's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Noriko Uchiyama with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Noriko Uchiyama more than expected).

Fields of papers citing papers by Noriko Uchiyama

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Noriko Uchiyama. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Noriko Uchiyama. The network helps show where Noriko Uchiyama may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Noriko Uchiyama, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Noriko Uchiyama Line = papers co-authored together Noriko Uchiyama links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of Rogocekib (CTX-712): A Potent and Selective CLK Inhibitor for Cancer Treatment ACS Medicinal Chemistry Letters ·Youichi Kawakita,Takuto Kojima,Noriyuki Nii,Y. ITO,Nobuki Sakauchi,Hiroshi Banno,Xin Liu,Koji Ono,Keisuke Imamura,Shinichi Imamura,Kenichi Iwai,Yukiko Yamamoto,Misa Iwatani,Noriko Uchiyama,Midori Sugiyama,Akio Mizutani,Yoshihiko Satoh,Yasuyoshi Arikawa,Daisuke Morishita,Kenichiro Shimokawa	2025	0
2	Discovery of a Novel and Brain-Penetrant O -GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead Optimization Journal of Medicinal Chemistry ·Michiko Tawada,Makoto Fushimi,Kei Masuda,Huikai Sun,Noriko Uchiyama,Yohei Kosugi,Weston Lane,Richard Tjhen,Satoshi Endo,Tatsuki Koike	2021	10
3	Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent Journal of Medicinal Chemistry ·Osamu Kurasawa,T. Miyazaki,Misaki Homma,Yuya Oguro,Takashi Imada,Noriko Uchiyama,Kenichi Iwai,Yukiko Yamamoto,Momoko Ohori,Hideto Hara,Hiroshi Sugimoto,Kentaro Iwata,R.J. Skene,Isaac Hoffman,Akihiro Ohashi,Toshiyuki Nomura,Nobuo Cho	2020	16
4	New phenotypic cytotoxicity assay for ROS-inducing compounds using rat renal epithelial cells Toxicology Letters ·Noriko Uchiyama,Tomoya Yukawa,Yvonne P. Dragan,Matthew P. Wagoner,Russell Naven	2020	1
5	Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase Journal of Medicinal Chemistry ·Yuta Tanaka,Osamu Kurasawa,Akihiro Yokota,Michael G. Klein,Koji Ono,Bunnai Saito,Shigemitsu Matsumoto,Masanori Okaniwa,Géza Ambrus-Aikelin,Daisuke Morishita,Satoshi Kitazawa,Noriko Uchiyama,Kazumasa Ogawa,Hiromichi Kimura,Shinichi Imamura	2020	19
6	Discovery of 3-Benzyl-1-(trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors Journal of Medicinal Chemistry ·Masahiro Ito,Toshio Tanaka,Akinori Toita,Noriko Uchiyama,Hironori Kokubo,Nao Morishita,Michael G. Klein,Hua Zou,Morio Murakami,Mitsuyo Kondo,Tomoya Sameshima,Shinsuke Araki,Satoshi Endo,Tomohiro Kawamoto,Gregg B. Morin,Samuel Aparício,Atsushi Nakanishi,Hironobu Maezaki,Yasuhiro Imaeda	2018	51
7	Identification of AHCY inhibitors using novel high-throughput mass spectrometry Biochemical and Biophysical Research Communications ·Noriko Uchiyama,Douglas R. Dougan,J. David Lawson,H. Kimura,Shin-ichi Matsumoto,Yukiya Tanaka,Tomohiro Kawamoto	2017	9
8	Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders Journal of Medicinal Chemistry ·Satoshi Mikami,Shinji Nakamura,Tomoko Ashizawa,Izumi Nomura,Masanori Kawasaki,Shigekazu Sasaki,Hideyuki Oki,Hironori Kokubo,Isaac Hoffman,Hua Zou,Noriko Uchiyama,Kosuke Nakashima,Naomi Kamiguchi,Haruka Imada,Noriko Suzuki,Hiroki Iwashita,Takahiko Taniguchi	2017	26
9	Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a European Journal of Pharmacology ·Noriko Uchiyama,Yukiya Tanaka,Tomohiro Kawamoto	2017	16
10	2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase Bioorganic & Medicinal Chemistry ·Osamu Kurasawa,Misaki Homma,Yuya Oguro,T. Miyazaki,Kouji Mori,Noriko Uchiyama,Kenichi Iwai,Akihiro Ohashi,Hideto Hara,Sei Yoshida,Nobuo Cho	2017	10
11	Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Andre A. Kiryanov,Srinivasa Reddy Natala,Benjamin Jones,Christopher M. McBride,Victoria A. Feher,Betty Lam,Yan Liu,Kouhei Honda,Noriko Uchiyama,Tomohiro Kawamoto,Yuichi Hikichi,Lilly Zhang,David J. Hosfield,R.J. Skene,Hua Zou,Jeffrey A. Stafford,Xiaodong Cao,Takashi Ichikawa	2016	13
12	A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity European Journal of Cancer ·Kenji Iwai,N. Tadahiro,Osamu Kurasawa,Noriko Uchiyama,Akihiro Ohashi	2016	2
13	Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives Journal of Medicinal Chemistry ·Masanori Okaniwa,Masaaki Hirose,Takeo Arita,Masato Yabuki,Akito Nakamura,Terufumi Takagi,Tomohiro Kawamoto,Noriko Uchiyama,Akihiko Sumita,Shunichirou Tsutsumi,Tsuneaki Tottori,Yoshitaka Inui,Bi‐Ching Sang,Jason K. Yano,Kathleen Aertgeerts,Sei Yoshida,Tomoyasu Ishikawa	2013	90
14	TAK-960, a Novel, Orally Available, Selective Inhibitor of Polo-Like Kinase 1, Shows Broad-spectrum Preclinical Antitumor Activity in Multiple Dosing Regimens Molecular Cancer Therapeutics ·Yuichi Hikichi,Kohei Honda,Kouki Hikami,Hitoshi Miyashita,Isao Kaieda,Saomi Murai,Noriko Uchiyama,Maki Hasegawa,Tomohiro Kawamoto,Takashi Sato,Takashi Ichikawa,Sheldon Cao,Zhe Nie,Lilly Zhang,Johnny Yang,Keisuke Kuida,Erik Kupperman	2011	64
15	A novel glycogen synthase kinase‐3 inhibitor 2‐methyl‐5‐(3‐{4‐[(S )‐methylsulfinyl]phenyl}‐1‐benzofuran‐5‐yl)‐1,3,4‐oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer’s disease Journal of Neurochemistry ·Tomohiro Onishi,Hiroki Iwashita,Yumiko Uno,Jun Kunitomo,Morihisa Saitoh,Eiji Kimura,Hisashi Fujita,Noriko Uchiyama,Masakuni Kori,Masayuki Takizawa	2011	75
16	Design, synthesis and structure–activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3β Bioorganic & Medicinal Chemistry ·Morihisa Saitoh,Jun Kunitomo,Eiji Kimura,Yoji Hayase,Hiromi Kobayashi,Noriko Uchiyama,Tomohiro Kawamoto,Toshimasa Tanaka,Clifford D. Mol,Douglas R. Dougan,Garret S. Textor,G. Snell,Fumio Itoh	2009	91
17	Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice Brain Research ·Yumiko Uno,Hiroki Iwashita,Tetsuya Tsukamoto,Noriko Uchiyama,Tomohiro Kawamoto,Masakuni Kori,Atsushi Nakanishi	2009	23
18	2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole Derivatives as Novel Inhibitors of Glycogen Synthase Kinase-3β with Good Brain Permeability Journal of Medicinal Chemistry ·Morihisa Saitoh,Jun Kunitomo,Eiji Kimura,Hiroki Iwashita,Yumiko Uno,Tomohiro Onishi,Noriko Uchiyama,Tomohiro Kawamoto,Toshimasa Tanaka,Clifford D. Mol,Douglas R. Dougan,Garret P. Textor,G. Snell,Masayuki Takizawa,Fumio Itoh,Masakuni Kori	2009	101
19	Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment The Journal of Experimental Medicine ·Atsushi Iwama,Mitsujiro Osawa,Ryutaro Hirasawa,Noriko Uchiyama,Shin Kaneko,Masafumi Onodera,Kazuko Shibuya,Akira Shibuya,Charles Vinson,Daniel G. Tenen,Hiromitsu Nakauchi	2002	89
20	Giant Solitary Sebaceous Gland Hyperplasia on the Frontal Region Dermatology ·Noriko Uchiyama,Kazuhiko Yamaji,Yasuko Shindo	1990	7

About Noriko Uchiyama

Noriko Uchiyama is a scholar working on Organic Chemistry, Cell Biology and Toxicology, having authored 28 papers that have together received 769 indexed citations. Recurring topics across this work include Wnt/β-catenin signaling in development and cancer (4 papers), Microtubule and mitosis dynamics (3 papers), Cancer-related Molecular Pathways (3 papers), Synthesis and biological activity (2 papers), Chronic Lymphocytic Leukemia Research (2 papers), Genetic and rare skin diseases. (2 papers), Synthesis and Reactivity of Heterocycles (2 papers) and Melanoma and MAPK Pathways (2 papers). The work is most often cited by research in Molecular Biology (477 citations), Organic Chemistry (183 citations) and Computational Theory and Mathematics (100 citations). Noriko Uchiyama has collaborated with scholars based in Japan, United States and Canada. Frequent co-authors include Tomohiro Kawamoto, Morihisa Saitoh, Eiji Kimura, Jun Kunitomo, Hiroki Iwashita, Masakuni Kori, Yumiko Uno, Douglas R. Dougan, Tomohiro Onishi and Masayuki Takizawa. Their work appears in journals such as The Journal of Experimental Medicine, Brain Research and Biochemical and Biophysical Research Communications.

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