Isaac Hoffman

590 total citations
13 papers, 227 citations indexed

About

Isaac Hoffman is a scholar working on Molecular Biology, Organic Chemistry and Surgery. According to data from OpenAlex, Isaac Hoffman has authored 13 papers receiving a total of 227 indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 6 papers in Organic Chemistry and 2 papers in Surgery. Recurrent topics in Isaac Hoffman's work include Synthesis and Reactivity of Heterocycles (2 papers), Synthesis and Catalytic Reactions (2 papers) and Quinazolinone synthesis and applications (2 papers). Isaac Hoffman is often cited by papers focused on Synthesis and Reactivity of Heterocycles (2 papers), Synthesis and Catalytic Reactions (2 papers) and Quinazolinone synthesis and applications (2 papers). Isaac Hoffman collaborates with scholars based in United States and Japan. Isaac Hoffman's co-authors include Hua Zou, Leslie W. Tari, Ronald V. Swanson, Michael J. Hunter, R.J. Skene, Kirk Nelson, Bi‐Ching Sang, Duncan E. McRee, Jay C. Nix and Daniel C. Bensen and has published in prestigious journals such as Journal of Medicinal Chemistry, Journal of Orthopaedic Research® and Bioorganic & Medicinal Chemistry.

In The Last Decade

Isaac Hoffman

13 papers receiving 215 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Isaac Hoffman United States 11 133 68 51 26 19 13 227
Preetpal S. Sidhu United States 11 103 0.8× 91 1.3× 21 0.4× 35 1.3× 19 1.0× 18 315
Jaclyn R. Patterson United States 8 225 1.7× 71 1.0× 28 0.5× 15 0.6× 16 0.8× 9 360
Matthew W. Martin United States 12 204 1.5× 107 1.6× 84 1.6× 14 0.5× 36 1.9× 19 338
Qiao Sun China 7 154 1.2× 138 2.0× 34 0.7× 22 0.8× 19 1.0× 8 311
Misaki Homma Japan 6 146 1.1× 51 0.8× 37 0.7× 21 0.8× 13 0.7× 7 258
Kelly A. Teske United States 11 197 1.5× 76 1.1× 36 0.7× 19 0.7× 6 0.3× 22 332
Daniele Volpi Italy 8 119 0.9× 70 1.0× 37 0.7× 15 0.6× 34 1.8× 13 254
Soumasree De India 9 231 1.7× 26 0.4× 24 0.5× 46 1.8× 16 0.8× 12 359
Rong Qu China 11 174 1.3× 110 1.6× 66 1.3× 12 0.5× 37 1.9× 15 347
Aikaterini Nikolaou Greece 9 196 1.5× 55 0.8× 31 0.6× 38 1.5× 44 2.3× 12 329

Countries citing papers authored by Isaac Hoffman

Since Specialization
Citations

This map shows the geographic impact of Isaac Hoffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac Hoffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac Hoffman more than expected).

Fields of papers citing papers by Isaac Hoffman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac Hoffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac Hoffman. The network helps show where Isaac Hoffman may publish in the future.

Co-authorship network of co-authors of Isaac Hoffman

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac Hoffman. A scholar is included among the top collaborators of Isaac Hoffman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac Hoffman. Isaac Hoffman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

13 of 13 papers shown
1.
Hudkins, Robert L., Eric Allen, Isaac Hoffman, et al.. (2024). Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia. Journal of Medicinal Chemistry. 67(18). 16737–16756. 10 indexed citations
2.
Hoffman, Isaac, et al.. (2022). Fatigue crack propagation and fracture toughness of cortical bone are radiation dose‐dependent. Journal of Orthopaedic Research®. 41(4). 823–833. 6 indexed citations
3.
Sasaki, Yusuke, Yusuke Ohba, Masaaki Nakayama, et al.. (2020). Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-oxopyrrolidine-4-carboxylates: Highly functionalized 2-pyrrolidinone enabling access to novel macrocyclic Tyk2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 30(5). 126963–126963. 14 indexed citations
4.
Kurasawa, Osamu, T. Miyazaki, Misaki Homma, et al.. (2020). Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent. Journal of Medicinal Chemistry. 63(3). 1084–1104. 16 indexed citations
5.
Fukase, Yoshiyuki, Atsuko Ochida, Kazuko Yonemori, et al.. (2017). Identification of novel quinazolinedione derivatives as RORγt inverse agonist. Bioorganic & Medicinal Chemistry. 26(3). 721–736. 17 indexed citations
6.
Kurasawa, Osamu, Yuya Oguro, T. Miyazaki, et al.. (2017). Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones. Bioorganic & Medicinal Chemistry. 25(7). 2133–2147. 14 indexed citations
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Okawa, Tomohiro, Yoshio Aramaki, Mitsuo Yamamoto, et al.. (2017). Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure. Journal of Medicinal Chemistry. 60(16). 6942–6990. 44 indexed citations
10.
Boloor, Amogh, Jason W. Brown, Andre A. Kiryanov, et al.. (2016). Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate. Bioorganic & Medicinal Chemistry Letters. 27(4). 1099–1104. 10 indexed citations
11.
Hoffman, Isaac. (2011). Protein Crystallization for Structure-Based Drug Design. Methods in molecular biology. 841. 67–91. 5 indexed citations
12.
Cianchetta, Giovanni, Terry R. Stouch, Wangsheng Yu, et al.. (2010). Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis. PubMed. 4. 19–26. 26 indexed citations
13.
Tari, Leslie W., Isaac Hoffman, Daniel C. Bensen, et al.. (2006). Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(3). 688–691. 29 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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