Samuel Aparício

84.9k citations

168 papers · 17.2k indexed · 8 hit papers · h-index 63

Impact in

Reproductive Medicine top 0.05%
- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
Cancer Research top 0.2%
- Cancer Genomics and Diagnostics

Papers in

Cancer Research 60
- Cancer Genomics and Diagnostics 42
- Breast Cancer Treatment Studies 12
Molecular Biology 120
- Single-cell and spatial transcriptomics 19
- Epigenetics and DNA Methylation 19
- Gene expression and cancer classification 17
- RNA modifications and cancer 13
- RNA Research and Splicing 12

Co-authors: Carlos Caldas Sydney Brenner Mark Carlton William H Colledge Dirk Zahn Alan G. Hendrick Rosemary R. Thresher Byrappa Venkatesh
Journals: Proceedings of the National Academy of Sciences (9 papers)Cancer Research (7 papers)PLoS ONE (7 papers)Nature Communications (6 papers)Oncogene (6 papers)
Partner nations: Canada United Kingdom United States

In The Last Decade

Samuel Aparício

163 papers receiving 16.9k citations

Hit Papers

8 papers align trajectories log scale

Breast tumor microenvironment structures are associated with genomic features and clinical outcome 2022 · 141 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Nature Genetics
2014 Nature Methods
2005 Proceedings of the National Academy of Sciences
2003 New England Journal of Medicine
2000 Nature
1995 Cell
1994 Nature
1993 Nature

Peers

Countries citing papers authored by Samuel Aparício

Since Specialization

Citations

This map shows the geographic impact of Samuel Aparício's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Samuel Aparício with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Samuel Aparício more than expected).

Fields of papers citing papers by Samuel Aparício

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Samuel Aparício. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Samuel Aparício. The network helps show where Samuel Aparício may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Samuel Aparício, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Samuel Aparício Line = papers co-authored together Samuel Aparício links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones Cell Reports ·Long Nguyen, 坂本一民, 寺尾秀三, 殷培霞, Suet‐Feung Chin, 春樹磯貝, Stephen‐John Sammut, Giulia Lerda, Daniela Virgínia Rios Dias de Medeiros, Helen Bardwell, Wendy Greenwood, Hyun Jin Shin, 서유경, Katarzyna Kania, Alejandra Bruna, Karl Strobel, 岩ケ谷愛, Samuel Aparício, Oscar M. Rueda, Carlos Caldas	2025	0
2	Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector Nature Communications ·Nicholas Ceglia, Zachary Sethna, Samuel S. Freeman, Florian Uhlitz, Viktoria Bojilova, Nicole Rusk, Xu Cheng, Andrew Chow, Sohrab Salehi, Farhia Kabeer, Samuel Aparício, Benjamin D. Greenbaum, Sohrab P. Shah, Andrew McPherson	2023	4
3	Cancer phylogenetic tree inference at scale from 1000s of single cell genomes SHILAP Revista de lepidopterología ·Sohrab Salehi, Philip Yeo, C. Chen, Farhia Kabeer, Nicole Rusk, Tyler Funnell, Marc Williams, Daniel Lai, Mirela Andronescu, Kieran R. Campbell, Andrew McPherson, Samuel Aparício, Andrew Roth, Sohrab P. Shah, Alexandre Bouchard‐Côté	2023	9
4	Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs PLoS ONE ·Yi Cui, Gaojie Yang, Daniel Goodwin, Ciara H. O’Flanagan, Anubhav Sinha, Chi Zhang, 郑静玉, Blahomil Soukup, Demian Park, Samuel Aparício, Edward S. Boyden	2023	10
5	Epiclomal: Probabilistic clustering of sparse single-cell DNA methylation data PLoS Computational Biology ·Camila P. E. de Souza, Mirela Andronescu, Tehmina Masud, Farhia Kabeer, Justina Biele, Emma Laks, Daniel Lai, ZHANG Zhihua, Jazmine Brimhall, ศิวะนัท ศรีสุนทร, 朱利东, Annmarie Meehan, Qi Cao, Anil S. Shirsat, Michelle Moksa, Richard A. Moore, Martin Hirst, Samuel Aparício, Sohrab P. Shah	2020	15
6	Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation Communications Biology ·Emad Ezzibdeh, Shinsuke Araki, Momoko Ohori, Amal M. El-Naggar, Damian Yap, Ali Bashashati, Gilda Galope Lum, Poul H. Sorensen, Atsushi Nakanishi, Sohrab P. Shah, Samuel Aparício	2019	30
7	clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers Genome biology ·Kieran R. Campbell, Adi Steif, Emma Laks, Hans Zahn, Daniel Lai, Andrew McPherson, Hossein Farahani, Farhia Kabeer, Ciara H. O’Flanagan, Justina Biele, Jazmine Brimhall, Beixi Wang, Alene Trachtenberg, Alexandre Bouchard‐Côté, Samuel Aparício, Sohrab P. Shah	2019	69
8	Discovery of 3-Benzyl-1-(trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors Journal of Medicinal Chemistry ·Masahiro Ito, Toshio Tanaka, Pisit Charo, Noriko Uchiyama, Hironori Kokubo, 孟庆方, Michael G. Klein, Hua Zou, S. Parry, Mitsuyo Kondo, Tomoya Sameshima, Shinsuke Araki, Satoshi Endo, Tomohiro Kawamoto, Gregg B. Morin, Samuel Aparício, Atsushi Nakanishi, Hironobu Maezaki, Yasuhiro Imaeda	2018	51
9	Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors Journal of Medicinal Chemistry ·Masahiro Ito, Toshio Tanaka, Douglas R. Cary, И. И. Бондарчук, Yusuke Kamada, Tomohiro Kawamoto, Samuel Aparício, Atsushi Nakanishi, Yasuhiro Imaeda	2017	28
10	Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay ACS Chemical Biology ·И. И. Бондарчук, Masahiro Ito, Yoshihiro Ishibashi, Hideyuki Oki, Toshio Tanaka, Daisuke Morishita, Takashi Ito, Hiromichi Kimura, Yasuhiro Imaeda, Samuel Aparício, Atsushi Nakanishi, Tomohiro Kawamoto	2017	30
11	ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data Genome biology ·Sohrab Salehi, Adi Steif, Andrew Roth, Samuel Aparício, Alexandre Bouchard‐Côté, Sohrab P. Shah	2017	41
12	Clonal genotype and population structure inference from single-cell tumor sequencing Nature Methods ·Andrew Roth, Andrew McPherson, Emma Laks, Justina Biele, Damian Yap, Adrian Wan, Maia A. Smith, Cydney Nielsen, Jessica N. McAlpine, Samuel Aparício, Alexandre Bouchard‐Côté, Sohrab P. Shah	2016	75
13	In Vivo Radioimaging of Bradykinin Receptor B1, a Widely Overexpressed Molecule in Human Cancer Cancer Research ·Kuo‐Shyan Lin, Jinhe Pan, Abel'tsev Np, Gulisa Turashvili, S Bindu, S. L. Wilcox, Maral Pourghiasian, Joseph Lau, Silvia Jenni, Samuel Aparício, François Bénard	2014	51
14	TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance Clinical Cancer Research ·Laxmi Silwal‐Pandit, Hans Kristian Moen Vollan, Suet‐Feung Chin, Oscar M. Rueda, Steven McKinney, Tomo Osako, David A. Quigley, Vessela N. Kristensen, Samuel Aparício, Anne‐Lise Børresen‐Dale, Carlos Caldas, Anita Langerød	2014	215
15	TDP1 and PARP1 Deficiency Are Cytotoxic to Rhabdomyosarcoma Cells Molecular Cancer Research ·黄思霞, Cheryl Walton, Kourtney Trudgen, 段冶, Tatjana Šelajeva, Kunho Choi, Guobin Sun, Syahid Abdullah, Maureen J. O’Sullivan, Gulisa Turashvili, Samuel Aparício, Timothy J. Triche, Mason Bond, Catherine J. Pallen, Cornelius F. Boerkoel	2013	33
16	High-throughput microfluidic single-cell RT-qPCR Proceedings of the National Academy of Sciences ·Adam K. White, Michael VanInsberghe, Oleh I. Petriv, Mani Hamidi, Darek Sikorski, Marco A. Marra, James M. Piret, Samuel Aparício, Carl L. Hansen	2011	355
17	Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas Cancer Research ·Jenny Potratz, Darren N. Saunders, Daniel Wai, Tony Ng, Steven McKinney, Joan M. Carboni, Marco M. Gottardis, Timothy J. Triche, Heribert Jürgens, Michaël Pollak, Samuel Aparício, Poul H. Sorensen	2010	55
18	Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene Proceedings of the National Academy of Sciences ·Xavier d’Anglemont de Tassigny, A. Illana, John Dixon, Kate Day, Harry G. Leitch, Alan G. Hendrick, Dirk Zahn, Isabelle Franceschini, Alain Caraty, Mark Carlton, Samuel Aparício, William H Colledge	2007	478
19	The GPR54 Gene as a Regulator of Puberty Obstetrical & Gynecological Survey ·Stephanie B. Seminara, Sophie Messager, Emmanouella E. Chatzidaki, Rosemary R. Thresher, James S. Acierno, Rock Xu, Carmen Mateos Alonso, Wendy Kuohung, Kristine M. Schwinof, Alan G. Hendrick, Dirk Zahn, John Dixon, Ursula B. Kaiser, Susan A. Slaugenhaupt, James F. Gusella, Stephen O’Rahilly, Mark Carlton, William F. Crowley, Samuel Aparício, William H Colledge	2004	173
20	Hiperplasia angiolinfoide con eosinofílica con buena respuesta al tratamiento con láser de colorante pulsado Actas Dermo-Sifiliográficas ·Samuel Aparício, Marcelo Moreno, Rennison Peter Lalgee, Paula Garcia, Mike Singh, P. Boixeda	2000	2

About Samuel Aparício

Samuel Aparício is a scholar working on Cancer Research, Molecular Biology, Oncology, Biophysics and Reproductive Medicine, having authored 168 papers that have together received 17.2k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (42 papers), Single-cell and spatial transcriptomics (19 papers), Epigenetics and DNA Methylation (19 papers), Gene expression and cancer classification (17 papers), Cancer Cells and Metastasis (15 papers), RNA modifications and cancer (13 papers), Breast Cancer Treatment Studies (12 papers) and RNA Research and Splicing (12 papers). The work is most often cited by research in Reproductive Medicine (3.6k citations), Cancer Research (3.7k citations), Endocrine and Autonomic Systems (1.1k citations), Molecular Biology (11.1k citations) and Genetics (3.4k citations). Samuel Aparício has collaborated with scholars based in Canada, United Kingdom and United States. Frequent co-authors include Carlos Caldas, Sydney Brenner, Mark Carlton, William H Colledge, Dirk Zahn, Alan G. Hendrick, Rosemary R. Thresher, Byrappa Venkatesh, Sohrab P. Shah and Sophie Messager. Their work appears in journals such as Proceedings of the National Academy of Sciences, Cancer Research, PLoS ONE, Nature Communications and Oncogene.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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