Takeo Arita

723 citations

11 papers · 408 indexed · 1 hit paper · h-index 7

Co-authors: Tomoyasu Ishikawa Masanori Okaniwa Sei Yoshida Akito Nakamura Masaya Nishino Akira Hamada Kenichi Suda Marco H. Hofmann
Topics: Melanoma and MAPK Pathways (7 papers)Synthesis and biological activity (5 papers)Computational Drug Discovery Methods (4 papers)
Cited by: Oncology Computational Theory and Mathematics Molecular Biology
Journals: Journal of Clinical Oncology Cancer Research Biochemical and Biophysical Research Communications
Partner nations: Japan United States Austria

In The Last Decade

Takeo Arita

11 papers receiving 404 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments

2021 167 citations T. Koga, Kenichi Suda et al. Journal of Thoracic Oncology profile →

Peers

Countries citing papers authored by Takeo Arita

Since Specialization

Citations

This map shows the geographic impact of Takeo Arita's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Takeo Arita with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Takeo Arita more than expected).

Fields of papers citing papers by Takeo Arita

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Takeo Arita. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Takeo Arita. The network helps show where Takeo Arita may publish in the future.

Co-authorship network of co-authors of Takeo Arita

This figure shows the co-authorship network connecting the top 25 collaborators of Takeo Arita. A scholar is included among the top collaborators of Takeo Arita based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Takeo Arita. Takeo Arita is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

11 of 11 papers shown

#	Work	Indexed citations
1	The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer 2024 ·Cancer Research Communications ·(unknown),Shohei Koyama,Fumitaka Suto,(unknown),(unknown),(unknown),Takeo Arita,(unknown),Hiroki Goto,Naoya Wada,Maki Kobayashi,Tomoko Shibutani,(unknown),Kenji Nakamaru,Akihito Kawazoe,Yosuke Togashi,Hiroyoshi Nishikawa,Kohei Shitara	1
2	KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experimentsbreakdown → 2021 ·Journal of Thoracic Oncology ·T. Koga,Kenichi Suda,Toshio Fujino,Shuta Ohara,Akira Hamada,Masaya Nishino,Masato Chiba,Masaki Shimoji,Toshiki Takemoto,Takeo Arita,Michael Gmachl,Marco H. Hofmann,Junichi Soh,Tetsuya Mitsudomi	167
3	Prolyl-tRNA synthetase inhibition promotes cell death in SK-MEL-2 cells through GCN2-ATF4 pathway activation 2017 ·Biochemical and Biophysical Research Communications ·Takeo Arita,Megumi Morimoto,Yukiko Yamamoto,Hitoshi Miyashita,Satoshi Kitazawa,Takaharu Hirayama,(unknown),Kazumasa Miyamoto,Ryutaro Adachi,Misa Iwatani,Takahito Hara	16
4	Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors 2016 ·Bioorganic & Medicinal Chemistry ·Taisuke Katoh,Takafumi Takai,(unknown),Tetsuya Tsukamoto,Etsurou Watanabe,Hideyuki Mototani,Takeo Arita,Hiroki Hayashi,Hideyuki Nakagawa,Michael G. Klein,Hua Zou,Bi‐Ching Sang,G. Snell,(unknown)	19
5	Antitumor Activity of the Selective Pan-RAF Inhibitor TAK-632 in BRAF Inhibitor-Resistant Melanoma 2013 ·Cancer Research ·Akito Nakamura,Takeo Arita,(unknown),Jill Donelan,(unknown),Elizabeth Carideo,Katherine Galvin,Masanori Okaniwa,Tomoyasu Ishikawa,Sei Yoshida	92
6	Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives 2013 ·Journal of Medicinal Chemistry ·Masanori Okaniwa,Masaaki Hirose,Takeo Arita,Masato Yabuki,Akito Nakamura,Terufumi Takagi,Tomohiro Kawamoto,Noriko Uchiyama,(unknown),Shunichirou Tsutsumi,(unknown),Yoshitaka Inui,Bi‐Ching Sang,Jason K. Yano,Kathleen Aertgeerts,Sei Yoshida,Tomoyasu Ishikawa	90
7	Use of combination treatment with the investigational RAF kinase inhibitor MLN2480 and the investigational MEK kinase inhibitor TAK-733 on the growth of BRAF-mutant and RAS-mutant preclinical models of melanoma and CRC. 2013 ·Journal of Clinical Oncology ·(unknown),Julie Zhang,(unknown),Jerome T. Mettetal,Kazuhide Nakamura,Takeo Arita,Akito Nakamura,Masanori Okaniwa,Tomoyasu Ishikawa,Sei Yoshida,(unknown),Patrick W. Vincent,(unknown),Khristofer Garcia,(unknown),(unknown),(unknown),Saurabh Menon,Mike Kuranda,Katherine Galvin	1
8	Abstract C255: Discovery of TAK-632: A selective kinase inhibitor of pan-RAF with potent antitumor activity against BRAF and NRAS mutant melanomas. 2013 ·Molecular Cancer Therapeutics ·Masanori Okaniwa,Masaaki Hirose,Takeo Arita,Masato Yabuki,Akito Nakamura,Terufumi Takagi,Tomohiro Kawamoto,Noriko Uchiyama,(unknown),Shunichirou Tsutsumi,(unknown),Yoshitaka Inui,Bi‐Ching Sang,Jason K. Yano,Kathleen Aertgeerts,Sei Yoshida,Tomoyasu Ishikawa	1
9	Abstract C146: Combination treatment with the investigational RAF kinase inhibitor MLN2480 and the investigational MEK kinase inhibitor TAK-733 inhibits the growth of BRAF mutant and RAS mutant preclinical models of melanoma and CRC. 2013 ·Molecular Cancer Therapeutics ·(unknown),Julie Zhang,(unknown),Jerome T. Mettetal,Kazuhide Nakamura,Takeo Arita,Akito Nakamura,Masanori Okaniwa,Tomoyasu Ishikawa,Sei Yoshida,(unknown),Patrick W. Vincent,(unknown),Khristofer Garcia,(unknown),(unknown),(unknown),Saurabh Menon,Mike Kuranda,Katherine Galvin	1
10	Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption 2012 ·Bioorganic & Medicinal Chemistry ·Masanori Okaniwa,Takashi Imada,Tomohiro Ohashi,T. Miyazaki,Takeo Arita,Masato Yabuki,(unknown),Shunichirou Tsutsumi,(unknown),Terufumi Takagi,Tomohiro Kawamoto,Yoshitaka Inui,Sei Yoshida,Tomoyasu Ishikawa	8
11	Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives 2012 ·Bioorganic & Medicinal Chemistry ·Masaaki Hirose,Masanori Okaniwa,T. Miyazaki,Takashi Imada,Tomohiro Ohashi,Yuta Tanaka,Takeo Arita,Masato Yabuki,Tomohiro Kawamoto,Shunichirou Tsutsumi,(unknown),Terufumi Takagi,Bi‐Ching Sang,Jason K. Yano,Kathleen Aertgeerts,Sei Yoshida,Tomoyasu Ishikawa	12

About Takeo Arita

Takeo Arita is a scholar working on Computational Theory and Mathematics, Gastroenterology and Organic Chemistry, having authored 11 papers that have together received 408 indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (7 papers), Synthesis and biological activity (5 papers) and Computational Drug Discovery Methods (4 papers). The work is most often cited by research in Oncology (151 citations), Computational Theory and Mathematics (74 citations) and Molecular Biology (319 citations). Takeo Arita has collaborated with scholars based in Japan, United States and Austria. Frequent co-authors include Tomoyasu Ishikawa, Masanori Okaniwa, Sei Yoshida, Akito Nakamura, Masaya Nishino, Akira Hamada, Kenichi Suda, Marco H. Hofmann, Tetsuya Mitsudomi and Michael Gmachl. Their work appears in journals such as Journal of Clinical Oncology, Cancer Research and Biochemical and Biophysical Research Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact