Jason K. Yano

4.9k total citations · 1 hit paper
29 papers, 3.6k citations indexed

About

Jason K. Yano is a scholar working on Molecular Biology, Oncology and Computational Theory and Mathematics. According to data from OpenAlex, Jason K. Yano has authored 29 papers receiving a total of 3.6k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 12 papers in Oncology and 11 papers in Computational Theory and Mathematics. Recurrent topics in Jason K. Yano's work include Computational Drug Discovery Methods (11 papers), Pharmacogenetics and Drug Metabolism (11 papers) and Drug Transport and Resistance Mechanisms (5 papers). Jason K. Yano is often cited by papers focused on Computational Drug Discovery Methods (11 papers), Pharmacogenetics and Drug Metabolism (11 papers) and Drug Transport and Resistance Mechanisms (5 papers). Jason K. Yano collaborates with scholars based in United States, Japan and Netherlands. Jason K. Yano's co-authors include Eric F. Johnson, Keith J. Griffin, G. Schoch, Michael R. Wester, C.D. Stout, C.D. Stout, Stefaan Sansen, T.L. Poulos, Kathleen Aertgeerts and Christine Yang and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Scientific Reports.

In The Last Decade

Jason K. Yano

27 papers receiving 3.5k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution

2004 585 citations Jason K. Yano, Michael R. Wester et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jason K. Yano United States	20	1.9k	1.6k	1.1k	1.0k	466	29	3.6k
Barry Jones United Kingdom	29	2.1k 1.1×	1.1k 0.7×	914 0.8×	1.1k 1.1×	213 0.5×	63	3.6k
Emily E. Scott United States	34	2.1k 1.1×	1.7k 1.0×	759 0.7×	760 0.7×	243 0.5×	86	3.9k
Deepak Dalvie United States	33	1.5k 0.8×	1.7k 1.1×	607 0.6×	609 0.6×	831 1.8×	76	4.0k
Irina F. Sevrioukova United States	33	1.6k 0.8×	1.8k 1.1×	566 0.5×	569 0.6×	254 0.5×	74	3.4k
Kenneth R. Korzekwa United States	34	2.7k 1.4×	1.1k 0.7×	658 0.6×	1.2k 1.2×	262 0.6×	63	3.9k
Ken Korzekwa United States	27	2.2k 1.2×	937 0.6×	461 0.4×	1.6k 1.5×	170 0.4×	67	3.4k
Keith J. Griffin United States	34	2.6k 1.4×	2.6k 1.6×	871 0.8×	1.3k 1.3×	143 0.3×	46	5.6k
G. Schoch France	18	1.5k 0.8×	1.5k 0.9×	729 0.7×	563 0.6×	129 0.3×	21	2.8k
Ronald E. White United States	28	1.5k 0.8×	1.5k 0.9×	296 0.3×	668 0.7×	581 1.2×	70	3.8k
Dijana Matak‐Vinković United Kingdom	24	976 0.5×	1.9k 1.2×	488 0.4×	556 0.5×	199 0.4×	41	3.2k

Countries citing papers authored by Jason K. Yano

Since Specialization

Citations

This map shows the geographic impact of Jason K. Yano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason K. Yano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason K. Yano more than expected).

Fields of papers citing papers by Jason K. Yano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason K. Yano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason K. Yano. The network helps show where Jason K. Yano may publish in the future.

Co-authorship network of co-authors of Jason K. Yano

This figure shows the co-authorship network connecting the top 25 collaborators of Jason K. Yano. A scholar is included among the top collaborators of Jason K. Yano based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jason K. Yano. Jason K. Yano is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tomlinson, Aidan C.A., John E. Knox, Luc Brunsveld, Christian Ottmann, & Jason K. Yano. (2025). The “three body solution”: Structural insights into molecular glues. Current Opinion in Structural Biology. 91. 103007–103007. 4 indexed citations

ITO, Y., Eiji Kimura, Izumi Nomura, et al.. (2025). Design and identification of brain-penetrant, potent, and selective 1,3-oxazole-based cholesterol 24-hydroxylase (CH24H) inhibitors. Bioorganic & Medicinal Chemistry. 124. 118182–118182.

Kajita, Y., Shuhei Ikeda, Masato Yoshikawa, et al.. (2022). Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. Journal of Medicinal Chemistry. 65(4). 3343–3358. 8 indexed citations

Nishi, Toshiya, Shinichi Kondo, Maki Miyamoto, et al.. (2020). Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice. Scientific Reports. 10(1). 17081–17081. 61 indexed citations

Aikawa, Katsuji, Koji Ono, Noriyuki Habuka, et al.. (2017). Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate. Bioorganic & Medicinal Chemistry. 25(13). 3330–3349. 36 indexed citations

Srivastava, Ankita, Jason K. Yano, Yoshihiko Hirozane, et al.. (2014). High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. Nature. 513(7516). 124–127. 288 indexed citations

Okaniwa, Masanori, Masaaki Hirose, Takeo Arita, et al.. (2013). Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives. Journal of Medicinal Chemistry. 56(16). 6478–6494. 90 indexed citations

Ishikawa, Tomoyasu, Masaki Seto, Hiroshi Banno, et al.. (2011). Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold. Journal of Medicinal Chemistry. 54(23). 8030–8050. 180 indexed citations

Maezaki, Hironobu, Yasufumi Miyamoto, Tomoko Asakawa, et al.. (2011). Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554. Bioorganic & Medicinal Chemistry. 19(15). 4482–4498. 28 indexed citations

10.

Aertgeerts, Kathleen, R.J. Skene, Jason K. Yano, et al.. (2011). Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. Journal of Biological Chemistry. 286(21). 18756–18765. 310 indexed citations

11.

Miyamoto, Yasufumi, Takashi Yamashita, Tatsuhiko Fujimoto, et al.. (2010). Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125. Bioorganic & Medicinal Chemistry. 19(1). 172–185. 23 indexed citations

12.

Schoch, G., Jason K. Yano, Stefaan Sansen, et al.. (2008). Determinants of Cytochrome P450 2C8 Substrate Binding. Journal of Biological Chemistry. 283(25). 17227–17237. 132 indexed citations

13.

Sansen, Stefaan, Jason K. Yano, G. Schoch, et al.. (2007). Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2. Journal of Biological Chemistry. 282(19). 14348–14355. 392 indexed citations

14.

Yano, Jason K., et al.. (2005). Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nature Structural & Molecular Biology. 12(9). 822–823. 245 indexed citations

15.

Yano, Jason K., Michael R. Wester, G. Schoch, et al.. (2004). The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution. Journal of Biological Chemistry. 279(37). 38091–38094. 585 indexed citations breakdown →

16.

Wester, Michael R., Jason K. Yano, G. Schoch, et al.. (2004). The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Å Resolution. Journal of Biological Chemistry. 279(34). 35630–35637. 361 indexed citations

17.

Schoch, G., Jason K. Yano, Michael R. Wester, et al.. (2004). Structure of Human Microsomal Cytochrome P450 2C8. Journal of Biological Chemistry. 279(10). 9497–9503. 314 indexed citations

18.

Yano, Jason K. & T.L. Poulos. (2003). New understandings of thermostable and peizostable enzymes. Current Opinion in Biotechnology. 14(4). 360–365. 65 indexed citations

19.

Li, Huiying, Jason K. Yano, & T.L. Poulos. (2002). Molecular replacement in P450 crystal structure determinations. Methods in enzymology on CD-ROM/Methods in enzymology. 357. 79–93. 4 indexed citations

20.

Yano, Jason K., Laura S. Koo, David J. Schuller, et al.. (2000). Crystal Structure of a Thermophilic Cytochrome P450 from the Archaeon Sulfolobus solfataricus. Journal of Biological Chemistry. 275(40). 31086–31092. 153 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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