Claudia Ruiz

1.4k citations

36 papers · 1.0k indexed · h-index 20

Organic Chemistry top 5%
- Synthesis and biological activity 8
- Quinazolinone synthesis and applications 4
Molecular Biology
- Melanoma and MAPK Pathways 14
- Protein Kinase Regulation and GTPase Signaling 12
Computational Theory and Mathematics top 5%
Pharmacology top 10%
- Inflammatory mediators and NSAID effects 3
- Microbial Natural Products and Biosynthesis 2
Oncology
Pathology and Forensic Medicine
- Cancer Mechanisms and Therapy 4
Genetics
- Chronic Lymphocytic Leukemia Research 2

Co-authors: Michael D. Cameron Lin Li Philip V. LoGrasso Thomas Schröter Yangbo Feng Marcel Koenig Yuanjun He Yan Yin
Cited by: Organic Chemistry Molecular Biology Computational Theory and Mathematics
Journals: Bioorganic & Medicinal Chemistry Letters (17 papers)Journal of Medicinal Chemistry (9 papers)Bioorganic & Medicinal Chemistry (3 papers)
Partner nations: United States China Austria

In The Last Decade

Claudia Ruiz

36 papers receiving 1.0k citations

Peers

Countries citing papers authored by Claudia Ruiz

Since Specialization

Citations

This map shows the geographic impact of Claudia Ruiz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Claudia Ruiz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Claudia Ruiz more than expected).

Fields of papers citing papers by Claudia Ruiz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Claudia Ruiz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Claudia Ruiz. The network helps show where Claudia Ruiz may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Claudia Ruiz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Claudia Ruiz Line = papers co-authored together Claudia Ruiz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents European Journal of Medicinal Chemistry ·Maria do Socorro Cirilo-Sousa,柏士珍,Marina Candido Primi,Minkoo Kang,Claudia Ruiz,Thales Kronenberger,Stefan Laufer,Márcia Inês Goettert,Antti Poso,Hafizhu Khofaria,Ding Liu,Eva Rothmeier,Neuza Mariko Aymoto Hassimotto,Michael D. Cameron,Thomas D. Bannister,Letícia V. Costa‐Lotufo,João Agostinho Machado‐Neto,Maurício T. Tavares,Roberto Parise‐Filho	2023	4
2	Development of a putative Zn2+-chelating but highly selective MMP-13 inhibitor Bioorganic & Medicinal Chemistry Letters ·Rita Fuerst,秀文山口,Anna M. Knapinska,Michael D. Cameron,Claudia Ruiz,Amber L. Delmas,Mark S. Sundrud,Gregg Fields,William Roush	2022	8
3	Structure–Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production Journal of Medicinal Chemistry ·Hua Lin,Kfir Sharabi,Lin Li,Claudia Ruiz,Di Zhu,Michael D. Cameron,Scott J. Novick,Patrick R. Griffin,Pere Puigserver,Theodore M. Kamenecka	2021	4
4	Development of matrix metalloproteinase-13 inhibitors – A structure-activity/structure-property relationship study Bioorganic & Medicinal Chemistry ·Rita Fuerst,秀文山口,Anna M. Knapinska,Lyndsay Smith,Michael D. Cameron,Claudia Ruiz,Gregg Fields,William Roush	2018	17
5	In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin Bioorganic & Medicinal Chemistry ·Liao‐Bin Dong,Jeffrey D. Rudolf,Li Lin,Claudia Ruiz,Michael D. Cameron,Ben Shen	2017	23
6	Amino acid derived quinazolines as Rock/PKA inhibitors Bioorganic & Medicinal Chemistry Letters ·Sarwat Chowdhury,Yen‐Ting Chen,X. M. Fang,Wayne Grant,Jennifer Pocas,Michael D. Cameron,Claudia Ruiz,Li Lin,HaJeung Park,Thomas Schröter,Thomas D. Bannister,Philip V. LoGrasso,Yangbo Feng	2013	13
7	Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors Bioorganic & Medicinal Chemistry Letters ·Yuanjun He,Derek R. Duckett,Wei‐Min Chen,Yuan Yuan Ling,Michael D. Cameron,Lin Li,Claudia Ruiz,Philip V. LoGrasso,Theodore M. Kamenecka,Marcel Koenig	2013	19
8	Imidazopyridines as selective CYP3A4 inhibitors Bioorganic & Medicinal Chemistry Letters ·Xinyi Song,Xiaohai Li,Claudia Ruiz,Yan Yin,Yangbo Feng,Theodore M. Kamenecka,Michael D. Cameron	2012	5
9	Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists Bioorganic & Medicinal Chemistry Letters ·Romain Noël,Xinyi Song,Youseung Shin,Subhashis Banerjee,Douglas J. Kojetin,Lin Li,Claudia Ruiz,Michael D. Cameron,Thomas P. Burris,Theodore M. Kamenecka	2012	22
10	Small molecule amides as potent ROR-γ selective modulators Bioorganic & Medicinal Chemistry Letters ·Maria‐Janieire de Nazaré Nunes Alves,Bahaa Elgendy,Naresh Kumar,Rubén D. Garcia-Ordoñez,Lin Li,Claudia Ruiz,Michael D. Cameron,Patrick R. Griffin,Theodore M. Kamenecka	2012	26
11	Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·X. M. Fang,Yen‐Ting Chen,E. Hampton Sessions,Sarwat Chowdhury,Tomáš Vojkovský,Yan Yin,Jennifer Pocas,Wayne Grant,Thomas Schröter,Lin Li,Claudia Ruiz,Michael D. Cameron,Philip V. LoGrasso,Thomas D. Bannister,Yangbo Feng	2011	27
12	Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I) Bioorganic & Medicinal Chemistry Letters ·Sarwat Chowdhury,E. Hampton Sessions,Jennifer Pocas,Wayne Grant,Thomas Schröter,Lin Li,Claudia Ruiz,Michael D. Cameron,Stephan C. Schürer,Philip V. LoGrasso,Thomas D. Bannister,Yangbo Feng	2011	38
13	Small Molecule c-jun-N-Terminal Kinase Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson’s Disease ACS Chemical Neuroscience ·Jeremy W. Chambers,Alok S. Pachori,Shannon Howard,Michelle L. Ganno,Albert Vierin,Ted Kamenecka,Xinyi Song,Derek R. Duckett,Wei‐Min Chen,Yuan Yuan Ling,Lisa Cherry,Michael D. Cameron,Li Lin,Claudia Ruiz,Philip V. LoGrasso	2011	52
14	Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Romain Noël,Youseung Shin,Xinyi Song,Yuanjun He,Marcel Koenig,Wei‐Min Chen,Yuan Yuan Ling,Lin Li,Claudia Ruiz,M.H. Balk,Michael D. Cameron,Derek R. Duckett,Theodore M. Kamenecka	2010	15
15	The development of benzimidazoles as selective rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·E. Hampton Sessions,Michael Smolinski,Bo Wang,Simona Frezzotti,Sarwat Chowdhury,Yan Yin,Yen‐Ting Chen,Claudia Ruiz,Lin Li,Jennifer Pocas,Thomas Schröter,Michael D. Cameron,Philip V. LoGrasso,Yangbo Feng,Thomas D. Bannister	2010	20
16	Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors Bioorganic & Medicinal Chemistry Letters ·Yan Yin,Lin Li,Claudia Ruiz,Michael D. Cameron,Jennifer Pocas,Wayne Grant,Thomas Schröter,Wei‐Min Chen,Derek R. Duckett,Stephan C. Schürer,Philip V. LoGrasso,Yangbo Feng	2009	40
17	Characterization of Dasatinib and Its Structural Analogs as CYP3A4 Mechanism-Based Inactivators and the Proposed Bioactivation Pathways Drug Metabolism and Disposition ·Xiaohai Li,Yuanjun He,Claudia Ruiz,Marcel Koenig,Michael D. Cameron	2009	134
18	Benzimidazole- and benzoxazole-based inhibitors of Rho kinase Bioorganic & Medicinal Chemistry Letters ·E. Hampton Sessions,Yan Yin,Thomas D. Bannister,Amiee Weiser,Выгодянский Алексей Валерьевич,Jennifer Pocas,Michael D. Cameron,Claudia Ruiz,Lin Li,Stephan C. Schürer,Thomas Schröter,Philip V. LoGrasso,Yangbo Feng	2008	82
19	Chroman-3-amides as potent Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Yen‐Ting Chen,Thomas D. Bannister,Amiee Weiser,Выгодянский Алексей Валерьевич,Lin Li,Claudia Ruiz,Michael D. Cameron,Stephan C. Schürer,Derek R. Duckett,Thomas Schröter,Philip V. LoGrasso,Yangbo Feng	2008	45
20	Structure–activity relationships, and drug metabolism and pharmacokinetic properties for indazole piperazine and indazole piperidine inhibitors of ROCK-II Bioorganic & Medicinal Chemistry Letters ·Yangbo Feng,Michael D. Cameron,Simona Frezzotti,Выгодянский Алексей Валерьевич,Lin Li,Claudia Ruiz,Thomas Schröter,Philip V. LoGrasso	2006	39

About Claudia Ruiz

Claudia Ruiz is a scholar working on Organic Chemistry, Molecular Biology and Pharmacology, having authored 36 papers that have together received 1.0k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (14 papers), Protein Kinase Regulation and GTPase Signaling (12 papers), Synthesis and biological activity (8 papers), Cancer Mechanisms and Therapy (4 papers), Quinazolinone synthesis and applications (4 papers), Inflammatory mediators and NSAID effects (3 papers), Chronic Lymphocytic Leukemia Research (2 papers) and Microbial Natural Products and Biosynthesis (2 papers). The work is most often cited by research in Organic Chemistry (399 citations), Molecular Biology (616 citations) and Computational Theory and Mathematics (126 citations). Claudia Ruiz has collaborated with scholars based in United States, China and Austria. Frequent co-authors include Michael D. Cameron, Lin Li, Philip V. LoGrasso, Thomas Schröter, Yangbo Feng, Marcel Koenig, Yuanjun He, Yan Yin, Xiaohai Li and Stephan C. Schürer. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, European Journal of Medicinal Chemistry and ACS Chemical Neuroscience.

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