Richard M. Locksley

64.2k total citations · 31 hit papers
271 papers, 51.4k citations indexed

About

Richard M. Locksley is a scholar working on Immunology, Public Health, Environmental and Occupational Health and Surgery. According to data from OpenAlex, Richard M. Locksley has authored 271 papers receiving a total of 51.4k indexed citations (citations by other indexed papers that have themselves been cited), including 182 papers in Immunology, 60 papers in Public Health, Environmental and Occupational Health and 48 papers in Surgery. Recurrent topics in Richard M. Locksley's work include Immune Cell Function and Interaction (97 papers), IL-33, ST2, and ILC Pathways (68 papers) and Research on Leishmaniasis Studies (56 papers). Richard M. Locksley is often cited by papers focused on Immune Cell Function and Interaction (97 papers), IL-33, ST2, and ILC Pathways (68 papers) and Research on Leishmaniasis Studies (56 papers). Richard M. Locksley collaborates with scholars based in United States, France and Germany. Richard M. Locksley's co-authors include Hong-Erh Liang, Nigel Killeen, Steven L. Reiner, Michael J. Lenardo, Ari B. Molofsky, Douglas T. Fearon, Steven J. Van Dyken, Ajay Chawla, M D Sadick and Frederick P. Heinzel and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Richard M. Locksley

267 papers receiving 50.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 3.0k citations Richard M. Locksley et al. Immunity profile →
The TNF and TNF Receptor Superfamilies

2001 2.9k citations Richard M. Locksley et al. Cell profile →
Innate lymphoid cells — a proposal for uniform nomenclature

2013 1.8k citations Richard M. Locksley et al. profile →
Requirement for IL-13 Independently of IL-4 in Experimental Asthma

1998 1.6k citations Markus Mohrs, Richard M. Locksley et al. Science profile →
Innate Lymphoid Cells: 10 Years On

2018 1.5k citations Richard M. Locksley et al. Cell profile →
The Instructive Role of Innate Immunity in the Acquired Immune Response

1996 1.3k citations Richard M. Locksley et al. Science profile →
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 1.3k citations B J Holaday, Richard M. Locksley et al. The Journal of Experimental Medicine profile →
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

2007 1.1k citations Richard M. Locksley et al. profile →
The Regulation of Immunity to Leishmania Major

1995 1.1k citations Richard M. Locksley et al. profile →
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

2011 1.1k citations Ari B. Molofsky, Hong-Erh Liang et al. Science profile →
Systemically dispersed innate IL-13–expressing cells in type 2 immunity

2010 902 citations Hong-Erh Liang, Brandon M. Sullivan et al. Proceedings of the National Academy of Sciences profile →
Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

2015 873 citations Jakob von Moltke, Hong-Erh Liang et al. profile →
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

2011 846 citations Richard M. Locksley et al. profile →
Type 2 innate lymphoid cells control eosinophil homeostasis

2013 831 citations Steven J. Van Dyken, Jakob von Moltke et al. profile →
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

2013 712 citations Ari B. Molofsky, Hong-Erh Liang et al. The Journal of Experimental Medicine profile →
Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

2014 682 citations Richard M. Locksley et al. Cell profile →
Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

2000 647 citations Gabriela G. Loots, Richard M. Locksley et al. Science profile →
Cytokine-secreting follicular T cells shape the antibody repertoire

2009 630 citations Hong-Erh Liang, Richard M. Locksley et al. profile →
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

2005 627 citations Richard M. Locksley et al. profile →
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1996 626 citations Richard M. Locksley et al. The Journal of Experimental Medicine profile →
Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

2013 601 citations Richard M. Locksley et al. Cell profile →
Chitin induces accumulation in tissue of innate immune cells associated with allergy

2007 597 citations Hong-Erh Liang, Nico van Rooijen et al. profile →
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 564 citations B J Holaday, Richard M. Locksley et al. The Journal of Experimental Medicine profile →
Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

2013 555 citations Steven J. Van Dyken, Richard M. Locksley profile →
Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

2014 543 citations Ari B. Molofsky, Richard M. Locksley et al. Cell profile →
Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

2008 500 citations Richard M. Locksley et al. Cell profile →
Interleukin-33 in Tissue Homeostasis, Injury, and Inflammation

2015 484 citations Ari B. Molofsky, Richard M. Locksley et al. Immunity profile →
Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

2018 374 citations Christoph Schneider, Richard M. Locksley et al. Immunity profile →
A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

2018 335 citations Christoph Schneider, Jakob von Moltke et al. Cell profile →
Tissue signals imprint ILC2 identity with anticipatory function

2018 327 citations Steven J. Van Dyken, Christoph Schneider et al. profile →
Pulmonary neuroendocrine cells amplify allergic asthma responses

2018 295 citations Steven J. Van Dyken, Richard M. Locksley et al. Science profile →

Peers

Countries citing papers authored by Richard M. Locksley

Since Specialization

Citations

This map shows the geographic impact of Richard M. Locksley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard M. Locksley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard M. Locksley more than expected).

Fields of papers citing papers by Richard M. Locksley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard M. Locksley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard M. Locksley. The network helps show where Richard M. Locksley may publish in the future.

Co-authorship network of co-authors of Richard M. Locksley

This figure shows the co-authorship network connecting the top 25 collaborators of Richard M. Locksley. A scholar is included among the top collaborators of Richard M. Locksley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Richard M. Locksley. Richard M. Locksley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB 2025 ·Cell ·(unknown), Tomoe Ishikawa, Hyeseung Lee, Byeongjun Lee, Changhyeon Ryu, (unknown), Minjin Kim, (unknown), Yujin Hong, Mengyang Feng, Hainsworth Y. Shin, Sylvain Meloche, Richard M. Locksley, Ekaterina K. Koltsova, Sergei I. Grivennikov, Myriam Heiman, Gloria B. Choi, Jun R. Huh	10
2	Interleukin-33–activated basophils promote asthma by regulating Th2 cell entry into lung tissue 2024 ·The Journal of Experimental Medicine ·Martijn J. Schuijs, (unknown), (unknown), Justine Van Moorleghem, Manon Vanheerswynghels, Geert Loo, Rudi Beyaert, David Voehringer, Richard M. Locksley, Hamida Hammad, Bart N. Lambrecht	19
3	Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites 2023 ·The Journal of Experimental Medicine ·(unknown), (unknown), (unknown), Martina Becker, (unknown), (unknown), (unknown), Wiebke Hartmann, (unknown), Tobias B. Huber, Christian F. Krebs, Ulf Panzer, Richard M. Locksley, Christoph Wilhelm, Minka Breloer, Jan‐Eric Turner	4
4	Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase 2023 ·eLife ·Roberto Efraín Díaz, (unknown), G.J. Correy, (unknown), I.D. Young, Bryan Faust, Michael C. Thompson, Ian B. Seiple, Steven J. Van Dyken, Richard M. Locksley, James S. Fraser	1
5	IL-13–programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function 2022 ·JCI Insight ·Maya E. Kotas, Camille M. Moore, José Gurrola, Steven D. Pletcher, Andrew N. Goldberg, (unknown), (unknown), Preston E. Bratcher, Ciarán A. Shaughnessy, Pamela L. Zeitlin, (unknown), Yingchun Li, Michael T. Montgomery, Keehoon Lee, Emily K. Cope, Richard M. Locksley, Max A. Seibold, Erin Gordon	27
6	Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation 2022 ·Immunity ·Kelly M. Cautivo, (unknown), Carlos O. Lizama, (unknown), Madelene W. Dahlgren, (unknown), (unknown), Marcela T Taruselli, Jeremy F. Brooks, (unknown), (unknown), (unknown), Hong-Erh Liang, Julie Zikherman, Richard M. Locksley, Ari B. Molofsky	37
7	Differences in the chitinolytic activity of mammalian chitinases on soluble and insoluble substrates 2020 ·Protein Science ·Benjamin A. Barad, Lin Liu, Roberto Efraín Díaz, (unknown), Steven J. Van Dyken, Richard M. Locksley, James S. Fraser	19
8	MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation 2017 ·The Journal of Experimental Medicine ·(unknown), Heather H. Pua, Hannah C. Happ, Christoph Schneider, Jakob von Moltke, Richard M. Locksley, Dirk Baumjohann, K. Mark Ansel	68
9	IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function 2015 ·The Journal of Experimental Medicine ·Laurence E. Cheng, Brandon M. Sullivan, (unknown), Christopher D.C. Allen, Hong-Erh Liang, Richard M. Locksley	65
10	Eosinophils Are Recruited in Response to Chitin Exposure and Enhance Th2-Mediated Immune Pathology in Aspergillus fumigatus Infection 2014 ·PMC ·(unknown), (unknown), Hongtao Li, (unknown), (unknown), Steven J. Van Dyken, Richard M. Locksley, Steven P. Templeton	1
11	Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages 2007 ·Journal of Leukocyte Biology ·David Voehringer, Nico van Rooijen, Richard M. Locksley	127
12	Replication Initiation from a Novel Origin Identified in the Th2 Cytokine Cluster Locus Requires a Distant Conserved Noncoding Sequence 2006 ·The Journal of Immunology ·Toshiro Hayashida, Masako Oda, (unknown), Atsumi Yamaguchi, (unknown), Richard M. Locksley, Mauro Giacca, Hisao Masai, Shoichiro Miyatake	15
13	Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection 2005 ·Proceedings of the National Academy of Sciences ·P’ng Loke, Xingxing Zang, (unknown), Rebecca Waitz, Richard M. Locksley, Judith E. Allen, James P. Allison	20
14	Mouse Vα14 i natural killer T cells are resistant to cytokine polarization in vivo 2003 ·Proceedings of the National Academy of Sciences ·Jennifer L. Matsuda, Laurent Gapin, Jody L. Baron, Stéphane Sidobre, Daniel B. Stetson, Markus Mohrs, Richard M. Locksley, Mitchell Kronenberg	203
15	Basal Chromatin Modification at the IL-4 Gene in Helper T Cells 2003 ·The Journal of Immunology ·Jane L. Grogan, Zhi‐En Wang, Sarah A. Stanley, (unknown), Gabriela G. Loots, Edward M. Rubin, Richard M. Locksley	32
16	Modulation of Blood Fluke Development in the Liver by Hepatic CD4 ⁺ Lymphocytes 2001 ·Science ·Stephen J. Davies, Jane L. Grogan, Rebecca B. Blank, K. C. Lim, Richard M. Locksley, James H. McKerrow	119
17	Coordinate Regulation of the IL-4, IL-13, and IL-5 Cytokine Cluster in Th2 Clones Revealed by Allelic Expression Patterns 2000 ·The Journal of Immunology ·Ben L. Kelly, Richard M. Locksley	105
18	Faithful Expression of the Human 5q31 Cytokine Cluster in Transgenic Mice 2000 ·The Journal of Immunology ·(unknown), Zhi‐En Wang, Derek J. Symula, (unknown), Edward M. Rubin, Kelly A. Frazer, Richard M. Locksley	15
19	Potential role for interleukin-10 in the immunosuppression associated with kala azar. 1993 ·Journal of Clinical Investigation ·B J Holaday, Margarida Maria de Lima Pompeu, Selma M. B. Jerônimo, (unknown), (unknown), A. W. Vasconcelos, Richard D. Pearson, J S Abrams, Richard M. Locksley	106
20	Acylation of monocyte and glomerular mesangial cell proteins. Myristyl acylation of the interleukin 1 precursors. 1988 ·Journal of Clinical Investigation ·Stuart L. Bursten, Richard M. Locksley, John L. Ryan, David H. Lovett	50

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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