Carsten Scaffidi

11.1k total citations · 5 hit papers
22 papers, 9.5k citations indexed

About

Carsten Scaffidi is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Carsten Scaffidi has authored 22 papers receiving a total of 9.5k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 11 papers in Immunology and 4 papers in Oncology. Recurrent topics in Carsten Scaffidi's work include Cell death mechanisms and regulation (15 papers), RNA Interference and Gene Delivery (8 papers) and Phagocytosis and Immune Regulation (4 papers). Carsten Scaffidi is often cited by papers focused on Cell death mechanisms and regulation (15 papers), RNA Interference and Gene Delivery (8 papers) and Phagocytosis and Immune Regulation (4 papers). Carsten Scaffidi collaborates with scholars based in Germany, United States and France. Carsten Scaffidi's co-authors include Marcus E. Peter, Peter H. Krammer, Ingo Schmitz, Frank Kischkel, Jian Ni, Andrej Shevchenko, Vishva M. Dixit, James D. Bretz, Karen O’Rourke and Matthias Mann and has published in prestigious journals such as Nature, Cell and Journal of Biological Chemistry.

In The Last Decade

Carsten Scaffidi

22 papers receiving 9.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 2.6k citations Marta Muzio, Arul M. Chinnaiyan et al. Cell profile →
Two CD95 (APO-1/Fas) signaling pathways

1998 2.5k citations Carsten Scaffidi The EMBO Journal profile →
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 1.1k citations Margot Thome, Pascal Schneider et al. Nature profile →
The Role of c-FLIP in Modulation of CD95-induced Apoptosis

1999 687 citations Carsten Scaffidi, Ingo Schmitz et al. Journal of Biological Chemistry profile →
Differential Modulation of Apoptosis Sensitivity in CD95 Type I and Type II Cells

1999 523 citations Carsten Scaffidi, Ingo Schmitz et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Carsten Scaffidi

Since Specialization

Citations

This map shows the geographic impact of Carsten Scaffidi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carsten Scaffidi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carsten Scaffidi more than expected).

Fields of papers citing papers by Carsten Scaffidi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carsten Scaffidi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carsten Scaffidi. The network helps show where Carsten Scaffidi may publish in the future.

Co-authorship network of co-authors of Carsten Scaffidi

This figure shows the co-authorship network connecting the top 25 collaborators of Carsten Scaffidi. A scholar is included among the top collaborators of Carsten Scaffidi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carsten Scaffidi. Carsten Scaffidi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Phosphorylation of FADD/ MORT1 at Serine 194 and Association with a 70-kDa Cell Cycle-Regulated Protein Kinase 2000 ·The Journal of Immunology ·Carsten Scaffidi, Jörg Volkland, (unknown), Ingrid Hoffmann, Peter H. Krammer, Marcus E. Peter	137
2	Analysis of the CD95 (APO-1/Fas) Death-Inducing Signaling Complex by High-Resolution Two-Dimensional Gel Electrophoresis 2000 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Carsten Scaffidi, Frank Kischkel, Peter H. Krammer, Marcus E. Peter	21
3	Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide 2000 ·Blood ·Fabienne Willems, Zoulikha Amraoui, Nathalie Vanderheyde, Valérie Verhasselt, Ezra Aksoy, Carsten Scaffidi, Marcus E. Peter, Peter H. Krammer, Michel Goldman	93
4	Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide 2000 ·Blood ·Fabienne Willems, Zoulikha Amraoui, Nathalie Vanderheyde, Valérie Verhasselt, Ezra Aksoy, Carsten Scaffidi, Marcus E. Peter, Peter H. Krammer, Michel Goldman	101
5	Apoptosis signaling in lymphocytes 1999 ·Current Opinion in Immunology ·Carsten Scaffidi, (unknown), Peter H. Krammer, Marcus E. Peter	178
6	Differential Modulation of Apoptosis Sensitivity in CD95 Type I and Type II Cells breakdown → 1999 ·Journal of Biological Chemistry ·Carsten Scaffidi, Ingo Schmitz, Jiping Zha, Stanley J. Korsmeyer, Peter H. Krammer, Marcus E. Peter	523
7	The Death Receptors 1999 ·Results and problems in cell differentiation ·Marcus E. Peter, Carsten Scaffidi, Jan Paul Medema, Frank Kischkel, Peter H. Krammer	69
8	Isolation and Analysis of Components of CD95 (APO-1/Fas) Death-Inducing Signaling Complex 1999 ·Methods ·Carsten Scaffidi, Peter H. Krammer, Marcus E. Peter	49
9	The Role of c-FLIP in Modulation of CD95-induced Apoptosis breakdown → 1999 ·Journal of Biological Chemistry ·Carsten Scaffidi, Ingo Schmitz, Peter H. Krammer, Marcus E. Peter	687
10	Activation of the CD95 (APO-1/Fas) pathway in drug- and γ-irradiation-induced apoptosis of brain tumor cells 1998 ·Cell Death and Differentiation ·Simone Fulda, Carsten Scaffidi, Torsten Pietsch, Peter H. Krammer, Marcus E. Peter, Klaus‐Michael Debatin	108
11	Bcl-xL Acts Downstream of Caspase-8 Activation by the CD95 Death-inducing Signaling Complex 1998 ·Journal of Biological Chemistry ·Jan Paul Medema, Carsten Scaffidi, Peter H. Krammer, Marcus E. Peter	104
12	Two CD95 (APO-1/Fas) signaling pathways breakdown → 1998 ·The EMBO Journal ·Carsten Scaffidi	2471
13	Caspase Activation Is Required for Nitric Oxide–Mediated, CD95(APO-1/Fas)–Dependent and Independent Apoptosis in Human Neoplastic Lymphoid Cells 1998 ·Blood ·Katerina Chlichlia, Marcus E. Peter, Marian Rocha, Carsten Scaffidi, Mariana Bucur, Peter H. Krammer, Volker Schirrmacher, Victor Umansky	68
14	Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid 1998 ·Journal of Biological Chemistry ·Simone Fulda, Carsten Scaffidi, Santos A. Susín, Peter H. Krammer, Guido Kroemer, Marcus E. Peter, Klaus‐Michael Debatin	325
15	Caspase Activation Is Required for Nitric Oxide–Mediated, CD95(APO-1/Fas)–Dependent and Independent Apoptosis in Human Neoplastic Lymphoid Cells 1998 ·Blood ·Katerina Chlichlia, Marcus E. Peter, Marian Rocha, Carsten Scaffidi, Mariana Bucur, Peter H. Krammer, Volker Schirrmacher, Victor Umansky	3
16	The role of p53 and the CD95 (APO-1/Fas) death system in chemotherapy-induced apoptosis. 1998 ·PubMed ·Martina Müller, Carsten Scaffidi, Peter R. Galle, Wolfgang Stremmel, Peter H. Krammer	38
17	Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors breakdown → 1997 ·Nature ·Margot Thome, Pascal Schneider, Kay Hofmann, Helmut Fickenscher, Edgar Meinl, Frank Neipel, Chantal Mattmann, Kim Burns, Jean-Luc Bodmer, Michael Schröter, Carsten Scaffidi, Peter H. Krammer, Marcus E. Peter, Jürg Tschopp	1066
18	FLICE Is Predominantly Expressed as Two Functionally Active Isoforms, Caspase-8/a and Caspase-8/b 1997 ·Journal of Biological Chemistry ·Carsten Scaffidi, Jan Paul Medema, Peter H. Krammer, Marcus E. Peter	359
19	Cleavage of FLICE (caspase‐8) by granzyme B during cytotoxic T lymphocyte‐induced apoptosis 1997 ·European Journal of Immunology ·Jan Paul Medema, René E. M. Toes, Carsten Scaffidi, Timothy S. Zheng, Richard A. Flavell, C.J.M. Melief, Marcus E. Peter, Rienk Offringa, Peter H. Krammer	126
20	FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex breakdown → 1996 ·Cell ·Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel, Karen O’Rourke, Andrej Shevchenko, Jian Ni, Carsten Scaffidi, James D. Bretz, Mei Zhang, Reiner Gentz, Matthias Mann, Peter H. Krammer, Marcus E. Peter, Vishva M. Dixit	2620

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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