Mark D. Fleming

32.0k total citations · 12 hit papers
227 papers, 22.4k citations indexed

About

Mark D. Fleming is a scholar working on Hematology, Genetics and Molecular Biology. According to data from OpenAlex, Mark D. Fleming has authored 227 papers receiving a total of 22.4k indexed citations (citations by other indexed papers that have themselves been cited), including 103 papers in Hematology, 73 papers in Genetics and 60 papers in Molecular Biology. Recurrent topics in Mark D. Fleming's work include Iron Metabolism and Disorders (76 papers), Hemoglobinopathies and Related Disorders (67 papers) and Trace Elements in Health (38 papers). Mark D. Fleming is often cited by papers focused on Iron Metabolism and Disorders (76 papers), Hemoglobinopathies and Related Disorders (67 papers) and Trace Elements in Health (38 papers). Mark D. Fleming collaborates with scholars based in United States, Germany and Canada. Mark D. Fleming's co-authors include Nancy C. Andrews, Dean R. Campagna, Marian H. Harris, Maureen A. Su, Robert E. Gerszten, Arvind Ramanathan, Heather R. Christofk, Matthew G. Vander Heiden, Ru Wei and Stuart L. Schreiber and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Mark D. Fleming

221 papers receiving 22.0k citations

Hit Papers

The M2 splice isoform of pyruvate kinase is important... 1997 2026 2006 2016 2008 1998 2000 2008 1997 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
    2008 2.2k citations Mark D. Fleming et al. profile →
  2. p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities
    1998 1.8k citations Mark D. Fleming, Nancy C. Andrews et al. profile →
  3. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
    2000 1.3k citations Geraldine S. Pinkus, Jack L. Pinkus et al. profile →
  4. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    2008 978 citations Mark D. Fleming et al. profile →
  5. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
    1997 975 citations Mark D. Fleming, Nancy C. Andrews et al. profile →
  6. Nramp 2 is mutated in the anemic Belgrade ( b ) rat: Evidence of a role for Nramp2 in endosomal iron transport
    1998 783 citations Mark D. Fleming, Nancy C. Andrews et al. profile →
  7. Recurrent BRAF mutations in Langerhans cell histiocytosis
    2010 742 citations Gayane Badalian‐Very, Jo‐Anne Vergilio et al. Blood profile →
  8. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    2001 677 citations Mark D. Fleming, William C. Hahn et al. profile →
  9. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
    2005 563 citations Dean R. Campagna, Yuko Fujiwara et al. profile →
  10. Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts
    2001 562 citations Mark D. Fleming et al. Blood profile →
  11. The Steap proteins are metalloreductases
    2006 539 citations Dean R. Campagna, Mark D. Fleming et al. Blood profile →
  12. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease
    2002 514 citations Mark D. Fleming, Nancy C. Andrews et al. Blood profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mark D. Fleming United States 67 9.2k 7.8k 5.5k 4.9k 3.5k 227 22.4k
Nancy C. Andrews United States 72 7.8k 0.8× 15.3k 2.0× 11.0k 2.0× 11.0k 2.2× 1.8k 0.5× 169 28.1k
Matthias W. Hentze Germany 107 25.4k 2.8× 11.6k 1.5× 6.9k 1.3× 7.6k 1.5× 4.7k 1.3× 306 40.1k
Earl W. Davie United States 81 6.4k 0.7× 12.0k 1.5× 5.7k 1.0× 2.0k 0.4× 1.9k 0.5× 189 21.3k
Ugo Testa Italy 68 8.7k 0.9× 4.9k 0.6× 2.3k 0.4× 597 0.1× 2.7k 0.8× 423 16.9k
Bernhard Nieswandt Germany 81 5.1k 0.6× 11.0k 1.4× 2.3k 0.4× 614 0.1× 1.2k 0.3× 321 22.9k
Hal E. Broxmeyer United States 89 10.1k 1.1× 9.6k 1.2× 4.2k 0.8× 618 0.1× 2.2k 0.6× 570 30.4k
David W. Golde United States 74 4.8k 0.5× 3.5k 0.5× 1.9k 0.3× 2.0k 0.4× 1.3k 0.4× 257 19.1k
Hidehiko Saito Japan 67 6.9k 0.7× 7.6k 1.0× 3.3k 0.6× 530 0.1× 1.2k 0.4× 484 18.5k
Søren K. Moestrup Denmark 85 7.7k 0.8× 2.3k 0.3× 1.3k 0.2× 963 0.2× 2.1k 0.6× 246 20.0k
C Peschle Italy 75 13.2k 1.4× 4.5k 0.6× 2.9k 0.5× 359 0.1× 5.3k 1.5× 321 22.7k

Countries citing papers authored by Mark D. Fleming

Since Specialization
Citations

This map shows the geographic impact of Mark D. Fleming's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark D. Fleming with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark D. Fleming more than expected).

Fields of papers citing papers by Mark D. Fleming

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark D. Fleming. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark D. Fleming. The network helps show where Mark D. Fleming may publish in the future.

Co-authorship network of co-authors of Mark D. Fleming

This figure shows the co-authorship network connecting the top 25 collaborators of Mark D. Fleming. A scholar is included among the top collaborators of Mark D. Fleming based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark D. Fleming. Mark D. Fleming is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cohen, Jennifer L., Michael Duyzend, Mark D. Fleming, et al.. (2025). Advancing precision care in pregnancy through a treatable fetal findings list. The American Journal of Human Genetics. 112(6). 1251–1269.
2.
Ducamp, Sarah, Min Wu, Juan Putra, et al.. (2025). The GLYT1 inhibitor bitopertin mitigates erythroid PPIX production and liver disease in erythroid protoporphyria. Journal of Clinical Investigation. 135(18). 1 indexed citations
3.
Ducamp, Sarah, Anoop K. Sendamarai, Dean R. Campagna, et al.. (2024). Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine. Blood. 144(13). 1418–1432. 4 indexed citations
4.
Petrova, Boryana, Alan Y. Wong, Peng Wang, et al.. (2024). Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis. Science Advances. 10(5). eadj9479–eadj9479. 6 indexed citations
5.
Bick, Nolan, et al.. (2024). Engineered bacterial lipoate protein ligase A (lplA) restores lipoylation in cell models of lipoylation deficiency. Journal of Biological Chemistry. 300(12). 107995–107995. 3 indexed citations
6.
Dickey, Amy K., Corbin Quick, Sarah Ducamp, et al.. (2020). Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria. Genetics in Medicine. 23(1). 140–148. 22 indexed citations
7.
Nguyen, Anthony T., Miguel A. Prado, Paul J. Schmidt, et al.. (2017). UBE2O remodels the proteome during terminal erythroid differentiation. Science. 357(6350). 118 indexed citations
8.
Fleming, Mark D., Manju Kalra, Gustavo S. Oderich, et al.. (2016). VESS24. Outcome of Peripheral Venous Reconstructions During Tumor Resection. Journal of Vascular Surgery. 63(6). 33S–33S. 2 indexed citations
9.
DeMartino, Randall R., Ying Huang, Mark D. Fleming, et al.. (2016). Outcomes of Women Treated for Popliteal Artery Aneurysms. Annals of Vascular Surgery. 34. 187–192. 7 indexed citations
10.
Gifford, Shaun M., Audra A. Duncan, Péter Gloviczki, et al.. (2016). The natural history and outcomes for thoracic and abdominal penetrating aortic ulcers. Journal of Vascular Surgery. 63(5). 1182–1188. 25 indexed citations
11.
Gifford, Shaun M., Thomas C. Bower, Audra A. Duncan, et al.. (2014). RR24. Long-Term Benefit of Open Renal Revascularization for Stent Failure. Journal of Vascular Surgery. 59(6). 105S–105S.
12.
Crompton, Brian D., Aaron R. Thorner, Amanda L. Christie, et al.. (2013). High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma. Cancer Research. 73(9). 2873–2883. 42 indexed citations
13.
Duncan, Audra A., Manju Kalra, William S. Harmsen, et al.. (2013). Single-Center Thirty-Two-Year Experience in the Treatment of Ruptured Abdominal Aortic Aneurysms. Journal of Vascular Surgery. 58(5). 1436–1437. 1 indexed citations
14.
Anderson, Sheila A., Christopher P. Nizzi, Yuan-I Chang, et al.. (2013). The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption. Cell Metabolism. 17(2). 282–290. 169 indexed citations
15.
Badalian‐Very, Gayane, Jo‐Anne Vergilio, Barbara Degar, et al.. (2010). Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 116(11). 1919–1923. 742 indexed citations breakdown →
16.
Kharas, Michael G., Christopher J. Lengner, Fátima Al‐Shahrour, et al.. (2010). Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. DSpace@MIT (Massachusetts Institute of Technology). 2 indexed citations
17.
Andrews, Nancy C., Mark D. Fleming, & Hiromi Gunshin. (2009). Iron Transport Across Biologic Membranes. Nutrition Reviews. 57(4). 114–123. 14 indexed citations
18.
Coughlin, Christina, Mark D. Fleming, Richard G. Carroll, et al.. (2006). Immunosurveillance and Survivin-Specific T-Cell Immunity in Children With High-Risk Neuroblastoma. Journal of Clinical Oncology. 24(36). 5725–5734. 73 indexed citations
19.
MacPherson, David, Jungho Kim, Teresa S. Kim, et al.. (2004). Defective apoptosis and B‐cell lymphomas in mice with p53 point mutation at Ser 23. The EMBO Journal. 23(18). 3689–3699. 94 indexed citations
20.
Canonne‐Hergaux, François, Mark D. Fleming, Joanne E. Levy, et al.. (2000). The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border.. Blood. 96(12). 3964–70. 91 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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